MA42049A - Sulfones tricycliques utiles commes modulateurs ror-gamma - Google Patents

Sulfones tricycliques utiles commes modulateurs ror-gamma

Info

Publication number
MA42049A
MA42049A MA042049A MA42049A MA42049A MA 42049 A MA42049 A MA 42049A MA 042049 A MA042049 A MA 042049A MA 42049 A MA42049 A MA 42049A MA 42049 A MA42049 A MA 42049A
Authority
MA
Morocco
Prior art keywords
sulphones
ror
tricyclic
useful
gamma modulators
Prior art date
Application number
MA042049A
Other languages
English (en)
Inventor
Douglas G Batt
Bertrand Myra Beaudoin
Robert J Cherney
Lyndon A M Cornelius
T G Murali Dhar
Jingwu Duan
Qingjie Liu
David Marcoux
Qing Shi
Anurag S Srivastava
Carolyn A Weigelt
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MA42049A publication Critical patent/MA42049A/fr

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    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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MA042049A 2015-05-07 2016-05-06 Sulfones tricycliques utiles commes modulateurs ror-gamma MA42049A (fr)

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CN110049985B (zh) * 2016-10-13 2022-05-31 百时美施贵宝公司 作为RORγ调节剂的杂环砜类
DE102017010487A1 (de) * 2016-12-02 2018-06-07 Merck Patent Gmbh Monofluorierte cyclohexane
KR102829200B1 (ko) * 2018-05-17 2025-07-02 브리스톨-마이어스 스큅 컴퍼니 Ror 감마 조정제로서의 트리시클릭 술폰 화합물
IL279348B2 (en) * 2018-06-15 2026-01-01 Reata Pharmaceuticals Inc Decahydro-2h-naphth[1,2-d]imidazole compounds for inhibition of IL-17 and ROR-gamma
CN112996795B (zh) 2018-09-18 2024-11-12 尼坎治疗公司 作为src同源-2磷酸酶抑制剂的稠合的三环衍生物
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KR102114536B1 (ko) 2020-05-22
AR104555A1 (es) 2017-07-26
TN2017000464A1 (en) 2019-04-12
PH12017502012A1 (en) 2018-04-02
BR112017023780A2 (pt) 2018-07-31
MA41389A1 (fr) 2018-06-29
US10273259B2 (en) 2019-04-30
US10711020B2 (en) 2020-07-14
CA2987759A1 (fr) 2016-11-10
AU2016258087B2 (en) 2020-01-02
UY36673A (es) 2016-11-30
US9815859B2 (en) 2017-11-14
MX2017014189A (es) 2018-04-13
US20160326195A1 (en) 2016-11-10
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MY190748A (en) 2022-05-12
CO2017012545A2 (es) 2018-05-10
IL255419A0 (en) 2017-12-31
JP2018515494A (ja) 2018-06-14
AU2016258087A1 (en) 2018-01-04
JP6553746B2 (ja) 2019-07-31
ES2887087T3 (es) 2021-12-21
EP3292101A1 (fr) 2018-03-14
EA033345B1 (ru) 2019-09-30
PE20180119A1 (es) 2018-01-18
CN107709295B (zh) 2021-05-04
TW201706244A (zh) 2017-02-16
US20180002358A1 (en) 2018-01-04
US20190241588A1 (en) 2019-08-08
EP3292101B1 (fr) 2021-07-28
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