MA42246A - Anticorps à domaine variable unique d'immunoglobuline contre la protéine f de pré-fusion de rsv - Google Patents

Anticorps à domaine variable unique d'immunoglobuline contre la protéine f de pré-fusion de rsv

Info

Publication number: MA42246A
Authority: MA; Morocco
Prior art keywords: variable domain; single variable; domain antibodies; immunoglobulin single; fusion immunoglobulin
Prior art date: 2015-06-18

Application number

MA042246A

Other languages

English (en)

Inventor

Morgan Gilman

Barney Graham

Jason Mclellan

Iebe Rossey

Xavier Saelens

Bert Schepens

Original Assignee

Us Health

Dartmouth College

Univ Gent

Vib Vzw

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-06-18

Filing date

2016-06-20

Publication date

2018-05-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57545045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA42246(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-07-28 Priority claimed from EP15178653.0A external-priority patent/EP3124042A1/fr

2016-06-20 Application filed by Us Health, Dartmouth College, Univ Gent, Vib Vzw filed Critical Us Health

2018-05-02 Publication of MA42246A publication Critical patent/MA42246A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pulmonology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

MA042246A 2015-06-18 2016-06-20 Anticorps à domaine variable unique d'immunoglobuline contre la protéine f de pré-fusion de rsv MA42246A (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201562181522P	2015-06-18	2015-06-18
EP15178653.0A EP3124042A1 (fr)	2015-07-28	2015-07-28	Anticorps à domaine variable unique contre la protéine f prefusion du virus respiratoire syncytial (rsv)
EP15191868		2015-10-28

Publications (1)

Publication Number	Publication Date
MA42246A true MA42246A (fr)	2018-05-02

Family

ID=57545045

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA042246A MA42246A (fr)	2015-06-18	2016-06-20	Anticorps à domaine variable unique d'immunoglobuline contre la protéine f de pré-fusion de rsv

Country Status (18)

Country	Link
US (2)	US10501528B2 (fr)
EP (1)	EP3313432A1 (fr)
JP (1)	JP6836760B2 (fr)
KR (1)	KR20180056631A (fr)
CN (1)	CN108472343B (fr)
AU (1)	AU2016277887B2 (fr)
BR (1)	BR112017027303A2 (fr)
CA (1)	CA2989378A1 (fr)
CL (1)	CL2017003260A1 (fr)
HK (1)	HK1254779A1 (fr)
IL (1)	IL256315B2 (fr)
MA (1)	MA42246A (fr)
MX (1)	MX394666B (fr)
MY (1)	MY192870A (fr)
PH (1)	PH12017502356B1 (fr)
RU (1)	RU2730671C2 (fr)
UA (1)	UA123584C2 (fr)
WO (1)	WO2016203052A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HK1254779A1 (zh) *	2015-06-18	2019-07-26	Vib Vzw	抗rsv融合前f蛋白的免疫球蛋白单可变结构域抗体
WO2019024979A1 (fr) *	2017-07-31	2019-02-07	Institute For Research In Biomedicine	Anticorps à domaines fonctionnels dans la région de coude
CN114805561B (zh) *	2019-08-02	2023-07-18	苏州高泓利康生物科技有限公司	针对呼吸道合胞病毒的蛋白结合分子
CN116063468A (zh) *	2022-08-30	2023-05-05	武汉班科生物技术有限公司	中和呼吸道合胞病毒的c-型单域抗体及应用
WO2025149667A1 (fr)	2024-01-12	2025-07-17	Pheon Therapeutics Ltd	Conjugués anticorps-médicament et leurs utilisations
WO2025228370A1 (fr) *	2024-04-29	2025-11-06	星济生物(苏州)有限公司	Protéine de liaison à l'antigène neutralisant le virus respiratoire syncytial et son utilisation
CN120329397A (zh) *	2024-12-26	2025-07-18	北京华诺泰生物医药科技有限公司	一种呼吸道合胞病毒f蛋白突变体及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1997830A1 (fr)	2007-06-01	2008-12-03	AIMM Therapeutics B.V.	Molécules à liaison spécifiques RSV et leur moyen de fabrication
JP5711972B2 (ja) *	2007-12-24	2015-05-07	アイディーバイオメディカルコーポレイションオブケベック	組換えｒｓｖ抗原
ES2713864T3 (es)	2008-06-05	2019-05-24	Ablynx Nv	Secuencias de aminoácidos dirigidas contra proteínas de la envuelta de un virus y polipéptidos que comprenden las mismas para el tratamiento de enfermedades virales
EP2438087B1 (fr) *	2009-06-05	2017-05-10	Ablynx N.V.	Nanobody trivalent contre le virus respiratoire syncytial humain (hrsv) pour la prevention et / ou le traitement des infections des voies respiratoires
US8568726B2 (en)	2009-10-06	2013-10-29	Medimmune Limited	RSV specific binding molecule
WO2011064382A1 (fr) *	2009-11-30	2011-06-03	Ablynx N.V.	Séquences d'acides aminés améliorées dirigées contre le virus syncytial respiratoire humain (hrsv) et polypeptides comprenant celles-ci pour la prévention et/ou le traitement d'infections du tractus respiratoire
HK1254779A1 (zh) *	2015-06-18	2019-07-26	Vib Vzw	抗rsv融合前f蛋白的免疫球蛋白单可变结构域抗体

2016
- 2016-06-20 HK HK18113825.4A patent/HK1254779A1/zh unknown
- 2016-06-20 BR BR112017027303-9A patent/BR112017027303A2/en not_active IP Right Cessation
- 2016-06-20 KR KR1020187001595A patent/KR20180056631A/ko not_active Ceased
- 2016-06-20 RU RU2018101662A patent/RU2730671C2/ru active
- 2016-06-20 MY MYPI2017001883A patent/MY192870A/en unknown
- 2016-06-20 MX MX2017016590A patent/MX394666B/es unknown
- 2016-06-20 AU AU2016277887A patent/AU2016277887B2/en not_active Ceased
- 2016-06-20 JP JP2017565829A patent/JP6836760B2/ja active Active
- 2016-06-20 EP EP16736013.0A patent/EP3313432A1/fr active Pending
- 2016-06-20 WO PCT/EP2016/064218 patent/WO2016203052A1/fr not_active Ceased
- 2016-06-20 CA CA2989378A patent/CA2989378A1/fr active Pending
- 2016-06-20 IL IL256315A patent/IL256315B2/en unknown
- 2016-06-20 CN CN201680046838.1A patent/CN108472343B/zh not_active Expired - Fee Related
- 2016-06-20 US US15/736,663 patent/US10501528B2/en active Active
- 2016-06-20 MA MA042246A patent/MA42246A/fr unknown
- 2016-06-20 UA UAA201800478A patent/UA123584C2/uk unknown
2017
- 2017-12-18 CL CL2017003260A patent/CL2017003260A1/es unknown
- 2017-12-18 PH PH12017502356A patent/PH12017502356B1/en unknown
2019
- 2019-09-10 US US16/566,542 patent/US11248039B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CL2017003260A1 (es)	2018-05-11
US11248039B2 (en)	2022-02-15
IL256315A (en)	2018-02-28
EP3313432A1 (fr)	2018-05-02
JP2018524979A (ja)	2018-09-06
CA2989378A1 (fr)	2016-12-22
CN108472343B (zh)	2021-12-10
PH12017502356A1 (en)	2018-06-25
AU2016277887B2 (en)	2022-06-09
AU2016277887A1 (en)	2018-01-18
MX2017016590A (es)	2018-11-09
BR112017027303A2 (en)	2018-09-04
UA123584C2 (uk)	2021-04-28
RU2730671C2 (ru)	2020-08-24
MX394666B (es)	2025-03-21
RU2018101662A (ru)	2019-07-22
US20180179266A1 (en)	2018-06-28
JP6836760B2 (ja)	2021-03-03
MY192870A (en)	2022-09-13
RU2018101662A3 (fr)	2019-11-06
US20200102374A1 (en)	2020-04-02
IL256315B2 (en)	2023-12-01
CN108472343A (zh)	2018-08-31
HK1254779A1 (zh)	2019-07-26
US10501528B2 (en)	2019-12-10
IL256315B1 (en)	2023-08-01
WO2016203052A1 (fr)	2016-12-22
KR20180056631A (ko)	2018-05-29
PH12017502356B1 (en)	2018-06-25

Publication	Publication Date	Title
MA42246A (fr)	2018-05-02	Anticorps à domaine variable unique d'immunoglobuline contre la protéine f de pré-fusion de rsv
DK3809884T3 (da)	2022-10-24	Nikotinposeprodukt
MA52742A (fr)	2021-04-14	Anticorps bispécifiques dll3-cd3
FR25C1022I1 (fr)	2025-08-01	Anticorps anti-pd-1
EP3817773A4 (fr)	2021-09-15	Anticorps humanisés dirigés contre c-kit
EP3500301A4 (fr)	2020-04-22	Anticorps bispécifiques de fab en tandem monovalents asymétriques
HUE051700T2 (hu)	2021-03-29	Anti-PD-1 antitestek
MA53297A (fr)	2022-05-04	Anticorps anti-icos
DK3411410T3 (da)	2021-06-07	Pd-1-antistoffer
MA42626A (fr)	2018-06-20	Nouveaux anticorps anti-pd-1
EP3334824A4 (fr)	2019-01-23	Anticorps anti-pd-1
EP3341861A4 (fr)	2019-03-06	Recommandation de vidéos d'après des titres de vidéos
EP3441086A4 (fr)	2019-11-13	Anticorps monoclonal anti-pd-1
EP3732239A4 (fr)	2021-07-07	Composition de polyéthylène
DK3649152T3 (da)	2025-11-10	ROR1-antistoffer
EP3383915A4 (fr)	2019-07-24	Anticorps anti-pd-1
IL270969A (en)	2020-01-30	Aggrecan binding immunoglobulins
IL270897A (en)	2020-01-30	Heterodimerizing ig domains
MD3475303T2 (ro)	2021-09-30	Formulări de anticorp anti-CD19
LT3652491T (lt)	2021-08-10	Produkto liofilizavimo būdas
EP3735420A4 (fr)	2021-10-06	Protéines de fusion anticorps-cytosine désaminase à domaine unique
PL3474904T3 (pl)	2024-12-16	Otrzymywanie przeciwciał monoklonalnych znakowanych 212pb
MA49250A (fr)	2021-04-14	Nouveaux anticorps anti-cd3
EP3522718A4 (fr)	2020-02-19	Récepteur d'antigène chimérique à domaine i spécifique d'icam-1
IL270908A (en)	2020-01-30	Adamts binding immunoglobulins