MA42692A - Compositions biopharmaceutiques - Google Patents

Compositions biopharmaceutiques

Info

Publication number
MA42692A
MA42692A MA042692A MA42692A MA42692A MA 42692 A MA42692 A MA 42692A MA 042692 A MA042692 A MA 042692A MA 42692 A MA42692 A MA 42692A MA 42692 A MA42692 A MA 42692A
Authority
MA
Morocco
Prior art keywords
biopharmaceutical compositions
biopharmaceutical
compositions
Prior art date
Application number
MA042692A
Other languages
English (en)
Inventor
Narendra B Bam
Jennifer Dally
Myrna A Monck
Michelle Spatara
Original Assignee
Glaxosmithkline Ip No 2 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56877084&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA42692(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Ip No 2 Ltd filed Critical Glaxosmithkline Ip No 2 Ltd
Publication of MA42692A publication Critical patent/MA42692A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA042692A 2015-08-24 2016-08-22 Compositions biopharmaceutiques MA42692A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562209000P 2015-08-24 2015-08-24
US201562240131P 2015-10-12 2015-10-12
US201562247906P 2015-10-29 2015-10-29
US201562249497P 2015-11-02 2015-11-02

Publications (1)

Publication Number Publication Date
MA42692A true MA42692A (fr) 2018-07-04

Family

ID=56877084

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042692A MA42692A (fr) 2015-08-24 2016-08-22 Compositions biopharmaceutiques

Country Status (23)

Country Link
US (11) US10870695B2 (fr)
EP (3) EP3341409B1 (fr)
JP (5) JP6821659B2 (fr)
KR (3) KR20250086801A (fr)
CN (5) CN116327922A (fr)
AU (1) AU2016311385C1 (fr)
BR (1) BR112018003741A2 (fr)
CA (1) CA2996088A1 (fr)
CL (1) CL2018000499A1 (fr)
CO (1) CO2018001840A2 (fr)
CR (1) CR20180115A (fr)
DO (1) DOP2018000057A (fr)
EA (1) EA037487B1 (fr)
ES (1) ES3053874T3 (fr)
IL (2) IL326469A (fr)
MA (1) MA42692A (fr)
MX (2) MX2018002319A (fr)
PE (1) PE20181176A1 (fr)
PH (1) PH12018500379B1 (fr)
TW (2) TWI750133B (fr)
UY (1) UY36868A (fr)
WO (1) WO2017033121A1 (fr)
ZA (1) ZA201801158B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116327922A (zh) * 2015-08-24 2023-06-27 葛兰素史密斯克莱知识产权(第2 号)有限公司 生物医药组合物
SG11201802769RA (en) 2015-10-29 2018-05-30 Novartis Ag Antibody conjugates comprising toll-like receptor agonist
TWI798179B (zh) * 2016-06-17 2023-04-11 美商建南德克公司 多特異性抗體之純化
CA3048186A1 (fr) 2016-12-23 2018-06-28 Cephalon, Inc. Anticorps anti-il-5
WO2018215964A1 (fr) * 2017-05-26 2018-11-29 Glaxosmithkline Intellectual Property Development Limited Compositions biopharmaceutiques et procédés associés
WO2018226339A1 (fr) * 2017-06-06 2018-12-13 Glaxosmithkline Llc Compositions biopharmaceutiques et procédés pour patients pédiatriques
JP7307720B2 (ja) 2017-09-29 2023-07-12 江蘇恒瑞医薬股▲ふん▼有限公司 Il-5抗体、その抗原結合フラグメント、およびそれらの医薬適用
WO2019224724A1 (fr) * 2018-05-23 2019-11-28 Glaxosmithkline Intellectual Property Development Limited Compositions biopharmaceutiques comprenant des variants d'anticorps
CA3134401A1 (fr) * 2019-03-29 2020-10-08 Jiangsu Hengrui Medicine Co., Ltd. Composition pharmaceutique contenant un anticorps anti-il-5 et son utilisation
JP2022540148A (ja) * 2019-07-10 2022-09-14 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 低減したレベルの宿主細胞タンパク質を含む方法および組成物
EP4077388A1 (fr) * 2019-12-18 2022-10-26 Tesaro, Inc. Compositions biopharmaceutiques et procédés associés
EP4272756A4 (fr) * 2021-02-05 2024-12-11 Bio-Thera Solutions, Ltd. Formulation d'anticorps anti-il-5, son procédé de préparation et son utilisation
CN118139883A (zh) * 2021-07-09 2024-06-04 詹森生物科技公司 用于生产抗tnf抗体组合物的制造方法
CN118251407A (zh) * 2021-09-22 2024-06-25 索诺玛生物治疗公司 Il5ra细胞表面标记物

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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SG49597A1 (en) 1992-02-06 1998-06-15 Schering Corp Design cloning and expression of humanized monoclonal antibodies against human interleukin-5
WO1995014040A1 (fr) * 1993-11-19 1995-05-26 Baylor College Of Medicine Anticorps monoclonaux specifiques de l'interleukine humaine 5
GB9412230D0 (en) 1994-06-17 1994-08-10 Celltech Ltd Interleukin-5 specific recombiant antibodies
US6056957A (en) 1994-08-04 2000-05-02 Schering Corporation Humanized monoclonal antibodies against human interleukin-5
ATE346867T1 (de) 1994-12-23 2006-12-15 Smithkline Beecham Corp Rekombinante il-5 antagonisten für die behandlung von il-5 bedingten krankheiten
US5683892A (en) 1994-12-23 1997-11-04 Smithkline Beecham Corporation DNA encoding recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
US5783184A (en) 1994-12-23 1998-07-21 Smithkline Beecham Corporation Method for treatment and diagnosis of IL-5 mediated disorders
US7399837B2 (en) 1995-12-22 2008-07-15 Smithkline Beecham Corporation Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
GB9712410D0 (en) 1997-06-14 1997-08-13 Glaxo Group Ltd Peptides and compounds that bind to the il-5 receptor
CA2559809A1 (fr) * 2004-03-12 2005-11-10 Human Genome Sciences, Inc. Anticorps diriges contre le polypeptide humain hdgnr10, un recepteur de chimiokine (ccr5) couple a des proteines-g
EP1739078A1 (fr) 2005-05-30 2007-01-03 Jerini AG Antagonistes du recepteur C5a
EP1988910B1 (fr) 2006-02-28 2017-12-06 Kodiak Sciences Inc. Conjugués de polymères contenant de l'acryloyloxyéthylphosphorylcholine et leur préparation
JP2010526087A (ja) 2007-04-30 2010-07-29 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗il−5抗体を投与するための方法
WO2009070642A1 (fr) 2007-11-28 2009-06-04 Medimmune, Llc Formulation de protéine
EP2222709B1 (fr) 2007-11-30 2016-11-23 Glaxo Group Limited Produits de construction de liaison à un antigène
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至her2結構域ii之抗體及其酸性變異體的組合物
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FR2944448B1 (fr) 2008-12-23 2012-01-13 Adocia Composition pharmaceutique stable comprenant au moins un anticorps monodonal et au moins un polysacharide amphiphile comprenant des substituants derives d'alcools hydrofobes ou d'amines hydrophobes.
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WO2012138958A1 (fr) * 2011-04-07 2012-10-11 Glaxosmithkline Llc Formulations ayant une viscosité réduite
SG193964A1 (en) 2011-04-07 2013-11-29 Glaxosmithkline Llc Formulations with reduced viscosity
EP2738172A1 (fr) 2012-11-28 2014-06-04 Almirall, S.A. Nouveaux composés bicycliques utilisés comme modulateurs du canal crac
KR20150129033A (ko) * 2013-03-14 2015-11-18 애브비 인코포레이티드 저 산성 종 조성물 및 이의 제조 및 사용 방법
WO2014141149A1 (fr) 2013-03-15 2014-09-18 Glaxosmithkline Intellectual Property (No.2) Limited Formulations présentant une viscosité réduite
EP2848615A1 (fr) 2013-07-03 2015-03-18 Almirall, S.A. Nouveaux dérivés de pyrazole utilisés comme modulateurs du canal CRAC
US20160235667A1 (en) 2013-10-02 2016-08-18 Vectura Limited Method and apparatus for making compositions for pulmonary administration
PL3097122T3 (pl) 2014-01-24 2020-10-19 Ngm Biopharmaceuticals, Inc. Przeciwciała wiążące domenę 2 beta klotho oraz sposoby ich stosowania
CA2935532A1 (fr) 2014-02-06 2015-08-13 Arsanis Biosciences Gmbh Sequences d'anticorps specifiques diriges contre e. coli
TW201705961A (zh) 2015-06-11 2017-02-16 阿爾米雷爾有限公司 作為jak抑制劑的2-(吡唑并吡啶-3-基)嘧啶衍生物
CN116327922A (zh) 2015-08-24 2023-06-27 葛兰素史密斯克莱知识产权(第2 号)有限公司 生物医药组合物

Also Published As

Publication number Publication date
EA037487B1 (ru) 2021-04-02
TW201722473A (zh) 2017-07-01
US20240294630A1 (en) 2024-09-05
US10870695B2 (en) 2020-12-22
JP2022023049A (ja) 2022-02-07
CN116474091A (zh) 2023-07-25
US20180251539A1 (en) 2018-09-06
US12187790B2 (en) 2025-01-07
EP4056590A1 (fr) 2022-09-14
CA2996088A1 (fr) 2017-03-02
JP2024123040A (ja) 2024-09-10
US20220380452A1 (en) 2022-12-01
MX2024001617A (es) 2024-03-06
KR20250086801A (ko) 2025-06-13
CN116327921A (zh) 2023-06-27
IL257539A (en) 2018-04-30
US11286298B2 (en) 2022-03-29
US20200199219A1 (en) 2020-06-25
KR20240099511A (ko) 2024-06-28
US11459384B2 (en) 2022-10-04
JP6821659B2 (ja) 2021-01-27
US20240294629A1 (en) 2024-09-05
KR20180037275A (ko) 2018-04-11
JP2026053516A (ja) 2026-03-25
DOP2018000057A (es) 2018-03-15
EA201890572A1 (ru) 2018-10-31
AU2016311385C1 (en) 2019-08-22
NZ739899A (en) 2025-05-02
CN116327923A (zh) 2023-06-27
US20210340246A1 (en) 2021-11-04
CN108137683A (zh) 2018-06-08
EP3341409B1 (fr) 2026-02-25
WO2017033121A1 (fr) 2017-03-02
AU2016311385A1 (en) 2018-03-15
US20240294628A1 (en) 2024-09-05
US12454571B2 (en) 2025-10-28
US11274148B2 (en) 2022-03-15
BR112018003741A2 (en) 2018-09-25
TWI750133B (zh) 2021-12-21
CR20180115A (es) 2018-04-12
PH12018500379B1 (en) 2022-11-23
MX2018002319A (es) 2018-04-11
US12187789B2 (en) 2025-01-07
CO2018001840A2 (es) 2018-05-31
PE20181176A1 (es) 2018-07-20
US20260049130A1 (en) 2026-02-19
PH12018500379A1 (en) 2018-09-03
CN116327922A (zh) 2023-06-27
TW202233238A (zh) 2022-09-01
CL2018000499A1 (es) 2018-07-06
US20210340247A1 (en) 2021-11-04
ZA201801158B (en) 2019-08-28
JP7463070B2 (ja) 2024-04-08
AU2016311385B2 (en) 2019-05-09
ES3053874T3 (en) 2026-01-27
US20220185878A1 (en) 2022-06-16
EP4056590B1 (fr) 2025-10-15
JP2020033351A (ja) 2020-03-05
IL326469A (en) 2026-04-01
US11299541B2 (en) 2022-04-12
TWI780988B (zh) 2022-10-11
US12187791B2 (en) 2025-01-07
EP4717700A2 (fr) 2026-04-01
EP3341409A1 (fr) 2018-07-04
US20210332125A1 (en) 2021-10-28
JP2018526369A (ja) 2018-09-13
IL257539B1 (en) 2026-03-01
UY36868A (es) 2017-03-31

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