MA44117A - Formulations de derives de phosphoramidate de composes de nucleoside - Google Patents
Formulations de derives de phosphoramidate de composes de nucleosideInfo
- Publication number
- MA44117A MA44117A MA044117A MA44117A MA44117A MA 44117 A MA44117 A MA 44117A MA 044117 A MA044117 A MA 044117A MA 44117 A MA44117 A MA 44117A MA 44117 A MA44117 A MA 44117A
- Authority
- MA
- Morocco
- Prior art keywords
- nucleoside compounds
- phosphoramidate derivatives
- phosphoramidate
- derivatives
- nucleoside
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1522764.8A GB201522764D0 (en) | 2015-12-23 | 2015-12-23 | Formulations of phosphate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA44117A true MA44117A (fr) | 2021-03-31 |
Family
ID=55311533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA044117A MA44117A (fr) | 2015-12-23 | 2016-12-21 | Formulations de derives de phosphoramidate de composes de nucleoside |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US20180369266A1 (fr) |
| EP (1) | EP3393453A1 (fr) |
| JP (2) | JP6913095B2 (fr) |
| KR (1) | KR20180091919A (fr) |
| CN (2) | CN108697636A (fr) |
| AU (3) | AU2016375866B2 (fr) |
| BR (2) | BR122023000551B1 (fr) |
| CA (1) | CA3008751C (fr) |
| CL (1) | CL2018001672A1 (fr) |
| EA (2) | EA037320B1 (fr) |
| GB (1) | GB201522764D0 (fr) |
| HK (1) | HK1255108A1 (fr) |
| IL (1) | IL260008B2 (fr) |
| MA (1) | MA44117A (fr) |
| MX (2) | MX385935B (fr) |
| MY (1) | MY196741A (fr) |
| PH (1) | PH12018501341B1 (fr) |
| SA (1) | SA518391858B1 (fr) |
| SG (2) | SG11201805318SA (fr) |
| WO (1) | WO2017109491A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0317009D0 (en) | 2003-07-21 | 2003-08-27 | Univ Cardiff | Chemical compounds |
| DK3031812T3 (en) | 2011-03-01 | 2018-09-17 | NuCana plc | CHEMICAL COMPOUNDS |
| WO2015198059A1 (fr) | 2014-06-25 | 2015-12-30 | Nucana Biomed Limited | Formulation comprenant un promédicament de gemcitabine |
| LT3224268T (lt) | 2014-11-28 | 2019-09-25 | NuCana plc | Naujieji 2` ir (arba) 5` aminorūgšties esterio fosforamidato 3`-deoksi adenozino dariniai, kaip priešvėžiniai junginiai |
| GB201609600D0 (en) | 2016-06-01 | 2016-07-13 | Nucuna Biomed Ltd | Cancer treatments |
| GB201709471D0 (en) | 2017-06-14 | 2017-07-26 | Nucana Biomed Ltd | Diastereoselective synthesis of hosphate derivatives |
| GB201713916D0 (en) * | 2017-08-30 | 2017-10-11 | Nucana Biomed Ltd | Treatment regimens |
| CN110840907B (zh) * | 2019-08-16 | 2022-11-25 | 南京医科大学 | 一类自由基敏感的尿嘧啶类ProTide前药及其药物用途 |
| AU2023268725A1 (en) | 2022-05-12 | 2024-12-12 | NuCana plc | Cancer treatment with nuc-7738 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070058028A (ko) | 1999-05-24 | 2007-06-07 | 소너스파머슈티칼즈인코포레이티드 | 난용성 약물용 에멀젼 부형제 |
| GB0412866D0 (en) | 2004-06-09 | 2004-07-14 | Novartis Ag | Organic compounds |
| AU2006208108A1 (en) | 2005-01-27 | 2006-08-03 | Erimos Pharmaceuticals Llc | Oral formulations for delivery of catecholic butanes including NDGA compounds |
| GB0505781D0 (en) * | 2005-03-21 | 2005-04-27 | Univ Cardiff | Chemical compounds |
| KR20140093764A (ko) | 2006-02-09 | 2014-07-28 | 산텐 세이야꾸 가부시키가이샤 | 안정한 제제와 그 제조 및 사용 방법 |
| US8759318B2 (en) * | 2009-01-09 | 2014-06-24 | Inhibitex, Inc. | Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections |
| EP2393815A4 (fr) | 2009-02-06 | 2012-11-21 | Rfs Pharma Llc | Promédicaments à base de purine nucléoside monophosphate pour le traitement du cancer et des infections virales |
| KR101201956B1 (ko) | 2009-03-18 | 2012-11-19 | 신동헌 | 파카스트리사민을 유효성분으로 함유하는 과증식성 피부질환과 악성흑색종의 예방 또는 치료용 약학적 조성물 |
| JP2012521359A (ja) | 2009-03-20 | 2012-09-13 | アリオス バイオファーマ インク. | 置換されたヌクレオシドアナログおよびヌクレオチドアナログ |
| NZ607996A (en) | 2010-09-22 | 2014-07-25 | Alios Biopharma Inc | Substituted nucleotide analogs |
| DK3031812T3 (en) * | 2011-03-01 | 2018-09-17 | NuCana plc | CHEMICAL COMPOUNDS |
| EP2681162A1 (fr) * | 2011-03-02 | 2014-01-08 | Koninklijke Philips N.V. | Verre à base de phosphate d'étain dans lequel des particules de matériau luminescent sont incrustées |
| EP2776438A4 (fr) | 2011-11-10 | 2015-04-29 | Inhibitex Inc | Nucléosides de purine substitués, dérivés phosphoramidate et phosphordiamidate destinés à traiter des infections virales |
| WO2013107515A1 (fr) | 2012-01-20 | 2013-07-25 | Okapi Sciences Nv | Composition de gouttes oculaires |
| US9125805B2 (en) | 2012-06-27 | 2015-09-08 | Xeris Pharmaceuticals, Inc. | Stable formulations for parenteral injection of small molecule drugs |
| EA033537B1 (ru) | 2013-03-11 | 2019-10-31 | Durect Corp | Инъекционная композиция с контролируемым высвобождением, содержащая жидкий носитель с высокой вязкостью |
| WO2015198059A1 (fr) * | 2014-06-25 | 2015-12-30 | Nucana Biomed Limited | Formulation comprenant un promédicament de gemcitabine |
| LT3224268T (lt) * | 2014-11-28 | 2019-09-25 | NuCana plc | Naujieji 2` ir (arba) 5` aminorūgšties esterio fosforamidato 3`-deoksi adenozino dariniai, kaip priešvėžiniai junginiai |
| GB201609600D0 (en) | 2016-06-01 | 2016-07-13 | Nucuna Biomed Ltd | Cancer treatments |
| GB201709471D0 (en) | 2017-06-14 | 2017-07-26 | Nucana Biomed Ltd | Diastereoselective synthesis of hosphate derivatives |
| GB201713916D0 (en) | 2017-08-30 | 2017-10-11 | Nucana Biomed Ltd | Treatment regimens |
| GB201715011D0 (en) | 2017-09-18 | 2017-11-01 | Nucana Biomed Ltd | Floxuridine synthesis |
-
2015
- 2015-12-23 GB GBGB1522764.8A patent/GB201522764D0/en not_active Ceased
-
2016
- 2016-12-21 MY MYPI2018001014A patent/MY196741A/en unknown
- 2016-12-21 IL IL260008A patent/IL260008B2/en unknown
- 2016-12-21 BR BR122023000551-1A patent/BR122023000551B1/pt active IP Right Grant
- 2016-12-21 SG SG11201805318SA patent/SG11201805318SA/en unknown
- 2016-12-21 SG SG10202008554RA patent/SG10202008554RA/en unknown
- 2016-12-21 CA CA3008751A patent/CA3008751C/fr active Active
- 2016-12-21 WO PCT/GB2016/054025 patent/WO2017109491A1/fr not_active Ceased
- 2016-12-21 HK HK18114263.1A patent/HK1255108A1/zh unknown
- 2016-12-21 MA MA044117A patent/MA44117A/fr unknown
- 2016-12-21 KR KR1020187020169A patent/KR20180091919A/ko active Pending
- 2016-12-21 CN CN201680082281.7A patent/CN108697636A/zh active Pending
- 2016-12-21 EA EA201891471A patent/EA037320B1/ru unknown
- 2016-12-21 PH PH1/2018/501341A patent/PH12018501341B1/en unknown
- 2016-12-21 MX MX2018007794A patent/MX385935B/es unknown
- 2016-12-21 US US16/065,402 patent/US20180369266A1/en not_active Abandoned
- 2016-12-21 JP JP2018532773A patent/JP6913095B2/ja active Active
- 2016-12-21 AU AU2016375866A patent/AU2016375866B2/en active Active
- 2016-12-21 EP EP16822242.0A patent/EP3393453A1/fr active Pending
- 2016-12-21 EA EA202190058A patent/EA202190058A1/ru unknown
- 2016-12-21 BR BR112018012951-8A patent/BR112018012951B1/pt active IP Right Grant
- 2016-12-21 CN CN202511368060.3A patent/CN121512923A/zh active Pending
-
2018
- 2018-06-20 CL CL2018001672A patent/CL2018001672A1/es unknown
- 2018-06-21 SA SA518391858A patent/SA518391858B1/ar unknown
- 2018-06-22 MX MX2021010601A patent/MX2021010601A/es unknown
-
2021
- 2021-04-15 US US17/231,606 patent/US11786544B2/en active Active
- 2021-07-09 JP JP2021113985A patent/JP7648458B2/ja active Active
-
2022
- 2022-08-02 AU AU2022211797A patent/AU2022211797B2/en active Active
-
2023
- 2023-09-22 US US18/371,865 patent/US12357652B2/en active Active
-
2024
- 2024-05-30 AU AU2024203637A patent/AU2024203637B2/en active Active
-
2025
- 2025-06-12 US US19/236,685 patent/US20250302859A1/en active Pending
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