MA44386A - Systèmes et méthodes de prédiction de demi-vie vitréenne de conjugués d'agent thérapeutique et de polymère - Google Patents

Systèmes et méthodes de prédiction de demi-vie vitréenne de conjugués d'agent thérapeutique et de polymère

Info

Publication number
MA44386A
MA44386A MA044386A MA44386A MA44386A MA 44386 A MA44386 A MA 44386A MA 044386 A MA044386 A MA 044386A MA 44386 A MA44386 A MA 44386A MA 44386 A MA44386 A MA 44386A
Authority
MA
Morocco
Prior art keywords
vitrean
life
systems
methods
therapeutic agent
Prior art date
Application number
MA044386A
Other languages
English (en)
Inventor
Robert Kelley
Justin Scheer
Whitney Shatz
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MA44386A publication Critical patent/MA44386A/fr

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16CCOMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30Prediction of properties of chemical compounds, compositions or mixtures
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10Complex mathematical operations
    • G06F17/18Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Data Mining & Analysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pure & Applied Mathematics (AREA)
  • Computational Mathematics (AREA)
  • Mathematical Analysis (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Physics (AREA)
  • Computing Systems (AREA)
  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Databases & Information Systems (AREA)
  • Probability & Statistics with Applications (AREA)
  • Algebra (AREA)
  • Operations Research (AREA)
  • Evolutionary Biology (AREA)
  • Software Systems (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA044386A 2015-10-07 2016-10-05 Systèmes et méthodes de prédiction de demi-vie vitréenne de conjugués d'agent thérapeutique et de polymère MA44386A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562238393P 2015-10-07 2015-10-07

Publications (1)

Publication Number Publication Date
MA44386A true MA44386A (fr) 2019-01-23

Family

ID=57211573

Family Applications (1)

Application Number Title Priority Date Filing Date
MA044386A MA44386A (fr) 2015-10-07 2016-10-05 Systèmes et méthodes de prédiction de demi-vie vitréenne de conjugués d'agent thérapeutique et de polymère

Country Status (7)

Country Link
US (1) US20180293360A1 (fr)
EP (1) EP3360066A1 (fr)
JP (1) JP2019501864A (fr)
CN (1) CN108369611A (fr)
HK (1) HK1259021A1 (fr)
MA (1) MA44386A (fr)
WO (1) WO2017062407A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102046661A (zh) 2008-03-28 2011-05-04 加利福尼亚大学董事会 多肽-聚合物偶联物和其使用方法
ES2925248T3 (es) 2015-12-09 2022-10-14 Univ California Métodos para tratar una enfermedad o un trastorno oculares
CN114617999B (zh) 2017-03-27 2024-12-27 里珍纳龙药品有限公司 灭菌方法
CN107261124B (zh) * 2017-06-09 2020-05-22 山东大学 一种新生血管生成抑制肽及其透明质酸修饰物的制备方法与应用
WO2020005767A1 (fr) * 2018-06-25 2020-01-02 The Board Of Regents Of The University Of Oklahoma Conjugués comportant des liaisons héparosane internes et d'extrémité terminale
CN118767255A (zh) 2019-06-05 2024-10-15 里珍纳龙药品有限公司 用于精确剂量递送的装置及方法
WO2021207197A2 (fr) * 2020-04-06 2021-10-14 Drive Therapeutics L.L.C. Compositions d'aptamères bispécifiques pour le traitement de troubles de la rétine
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI955320L (fi) 1994-03-07 1995-11-24 Dow Chemical Co Bioaktiivisia ja/tai kohdennettuja dendriimikonjugaatteja
US5675063A (en) 1995-02-28 1997-10-07 Loyola University Of Chicago Immortalized rabbit hybridoma fusion partner
KR19990085365A (ko) 1998-05-16 1999-12-06 허영섭 지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법
BRPI0613401B8 (pt) * 2005-10-18 2021-05-25 Allergan Inc composição oftálmica compreendendo derivados de glicocorticoides que penetram seletivamente nos tecidos do segmento posterior
US20110064717A1 (en) 2009-08-20 2011-03-17 Ramot At Tel-Aviv University Ltd. Homing endonuclease genes and their targets
US20120282211A1 (en) 2009-11-24 2012-11-08 Carnegie Mellon University Antibodies and conjugates for modulators of angiogenesis
ES2811065T3 (es) * 2010-05-11 2021-03-10 Hutchinson Fred Cancer Res Variantes de clorotoxina, conjugados y métodos para su utilización
TW201427989A (zh) 2012-12-18 2014-07-16 Novartis Ag 長效性蛋白質之組合物及方法

Also Published As

Publication number Publication date
US20180293360A1 (en) 2018-10-11
HK1259021A1 (zh) 2019-11-22
CN108369611A (zh) 2018-08-03
EP3360066A1 (fr) 2018-08-15
WO2017062407A1 (fr) 2017-04-13
JP2019501864A (ja) 2019-01-24

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