MA44518A - Procédés d'inhibition d'angiogenèse chez un sujet qui en a besoin - Google Patents

Procédés d'inhibition d'angiogenèse chez un sujet qui en a besoin

Info

Publication number
MA44518A
MA44518A MA044518A MA44518A MA44518A MA 44518 A MA44518 A MA 44518A MA 044518 A MA044518 A MA 044518A MA 44518 A MA44518 A MA 44518A MA 44518 A MA44518 A MA 44518A
Authority
MA
Morocco
Prior art keywords
subject
needs
angiogenesis inhibition
inhibition processes
processes
Prior art date
Application number
MA044518A
Other languages
English (en)
Inventor
Gregory A Demopulos
Thomas Dudler
Hans-Wilhelm Schwaeble
Larry Tjoelker
Original Assignee
Omeros Corp
Univ Leicester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omeros Corp, Univ Leicester filed Critical Omeros Corp
Publication of MA44518A publication Critical patent/MA44518A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA044518A 2016-03-31 2017-03-31 Procédés d'inhibition d'angiogenèse chez un sujet qui en a besoin MA44518A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662315857P 2016-03-31 2016-03-31

Publications (1)

Publication Number Publication Date
MA44518A true MA44518A (fr) 2019-02-06

Family

ID=59959191

Family Applications (1)

Application Number Title Priority Date Filing Date
MA044518A MA44518A (fr) 2016-03-31 2017-03-31 Procédés d'inhibition d'angiogenèse chez un sujet qui en a besoin

Country Status (20)

Country Link
US (3) US10870708B2 (fr)
EP (1) EP3436072A4 (fr)
JP (3) JP6865767B2 (fr)
KR (4) KR20180128941A (fr)
CN (3) CN117582494A (fr)
AU (2) AU2017240129B2 (fr)
BR (1) BR112018069732A2 (fr)
CA (2) CA3096270C (fr)
CL (1) CL2018002708A1 (fr)
EA (2) EA202191185A1 (fr)
GE (2) GEAP202214913A (fr)
IL (2) IL305200B2 (fr)
MA (1) MA44518A (fr)
MX (2) MX2018011648A (fr)
MY (1) MY195432A (fr)
NZ (1) NZ745531A (fr)
PH (1) PH12018502046B1 (fr)
SG (2) SG10202009886SA (fr)
WO (1) WO2017173290A1 (fr)
ZA (1) ZA202500956B (fr)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107638565B (zh) * 2011-04-08 2021-12-21 莱斯特大学 用于治疗与masp-2依赖性补体活化相关的状况的方法
JOP20170170B1 (ar) 2016-08-31 2022-09-15 Omeros Corp صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق
CN107537026A (zh) * 2017-08-31 2018-01-05 中山大学中山眼科中心 Vegf‑b的应用
CN107661492A (zh) * 2017-08-31 2018-02-06 中山大学中山眼科中心 Vegf‑b的新用途
US11584714B2 (en) 2018-05-29 2023-02-21 Omeros Corporation MASP-2 inhibitors and methods of use
CN118373875A (zh) 2018-05-29 2024-07-23 奥默罗斯公司 Masp-2抑制剂和使用方法
US11471729B2 (en) 2019-03-11 2022-10-18 Rom Technologies, Inc. System, method and apparatus for a rehabilitation machine with a simulated flywheel
US12029940B2 (en) 2019-03-11 2024-07-09 Rom Technologies, Inc. Single sensor wearable device for monitoring joint extension and flexion
US11801423B2 (en) 2019-05-10 2023-10-31 Rehab2Fit Technologies, Inc. Method and system for using artificial intelligence to interact with a user of an exercise device during an exercise session
US11433276B2 (en) 2019-05-10 2022-09-06 Rehab2Fit Technologies, Inc. Method and system for using artificial intelligence to independently adjust resistance of pedals based on leg strength
US12102878B2 (en) 2019-05-10 2024-10-01 Rehab2Fit Technologies, Inc. Method and system for using artificial intelligence to determine a user's progress during interval training
US11957960B2 (en) 2019-05-10 2024-04-16 Rehab2Fit Technologies Inc. Method and system for using artificial intelligence to adjust pedal resistance
US11904207B2 (en) 2019-05-10 2024-02-20 Rehab2Fit Technologies, Inc. Method and system for using artificial intelligence to present a user interface representing a user's progress in various domains
US11957956B2 (en) 2019-05-10 2024-04-16 Rehab2Fit Technologies, Inc. System, method and apparatus for rehabilitation and exercise
US11833393B2 (en) 2019-05-15 2023-12-05 Rehab2Fit Technologies, Inc. System and method for using an exercise machine to improve completion of an exercise
US11896540B2 (en) 2019-06-24 2024-02-13 Rehab2Fit Technologies, Inc. Method and system for implementing an exercise protocol for osteogenesis and/or muscular hypertrophy
US11071597B2 (en) 2019-10-03 2021-07-27 Rom Technologies, Inc. Telemedicine for orthopedic treatment
US12402804B2 (en) 2019-09-17 2025-09-02 Rom Technologies, Inc. Wearable device for coupling to a user, and measuring and monitoring user activity
US12176089B2 (en) 2019-10-03 2024-12-24 Rom Technologies, Inc. System and method for using AI ML and telemedicine for cardio-oncologic rehabilitation via an electromechanical machine
US11887717B2 (en) 2019-10-03 2024-01-30 Rom Technologies, Inc. System and method for using AI, machine learning and telemedicine to perform pulmonary rehabilitation via an electromechanical machine
US11282599B2 (en) 2019-10-03 2022-03-22 Rom Technologies, Inc. System and method for use of telemedicine-enabled rehabilitative hardware and for encouragement of rehabilitative compliance through patient-based virtual shared sessions
US11955220B2 (en) 2019-10-03 2024-04-09 Rom Technologies, Inc. System and method for using AI/ML and telemedicine for invasive surgical treatment to determine a cardiac treatment plan that uses an electromechanical machine
US12246222B2 (en) 2019-10-03 2025-03-11 Rom Technologies, Inc. Method and system for using artificial intelligence to assign patients to cohorts and dynamically controlling a treatment apparatus based on the assignment during an adaptive telemedical session
US12347543B2 (en) 2019-10-03 2025-07-01 Rom Technologies, Inc. Systems and methods for using artificial intelligence to implement a cardio protocol via a relay-based system
US12605613B2 (en) 2022-05-04 2026-04-21 Rom Technologies, Inc. Systems and methods for using smart exercise devices to perform cardiovascular rehabilitation
US11978559B2 (en) 2019-10-03 2024-05-07 Rom Technologies, Inc. Systems and methods for remotely-enabled identification of a user infection
US12562243B2 (en) 2019-10-03 2026-02-24 Rom Technologies, Inc. System and method for processing medical claims using biometric signatures
US12100499B2 (en) 2020-08-06 2024-09-24 Rom Technologies, Inc. Method and system for using artificial intelligence and machine learning to create optimal treatment plans based on monetary value amount generated and/or patient outcome
US11515021B2 (en) 2019-10-03 2022-11-29 Rom Technologies, Inc. Method and system to analytically optimize telehealth practice-based billing processes and revenue while enabling regulatory compliance
US11923065B2 (en) 2019-10-03 2024-03-05 Rom Technologies, Inc. Systems and methods for using artificial intelligence and machine learning to detect abnormal heart rhythms of a user performing a treatment plan with an electromechanical machine
US11961603B2 (en) 2019-10-03 2024-04-16 Rom Technologies, Inc. System and method for using AI ML and telemedicine to perform bariatric rehabilitation via an electromechanical machine
US11270795B2 (en) 2019-10-03 2022-03-08 Rom Technologies, Inc. Method and system for enabling physician-smart virtual conference rooms for use in a telehealth context
US12427376B2 (en) 2019-10-03 2025-09-30 Rom Technologies, Inc. Systems and methods for an artificial intelligence engine to optimize a peak performance
US12539446B2 (en) 2019-10-03 2026-02-03 Rom Technologies, Inc. Method and system for using sensors to optimize a user treatment plan in a telemedicine environment
US11075000B2 (en) 2019-10-03 2021-07-27 Rom Technologies, Inc. Method and system for using virtual avatars associated with medical professionals during exercise sessions
US12555667B2 (en) 2019-10-03 2026-02-17 Rom Technologies, Inc. Systems and methods for using AI/ML and for cardiac and pulmonary treatment via an electromechanical machine related to urologic disorders and antecedents and sequelae of certain urologic surgeries
US12154672B2 (en) 2019-10-03 2024-11-26 Rom Technologies, Inc. Method and system for implementing dynamic treatment environments based on patient information
US11955223B2 (en) 2019-10-03 2024-04-09 Rom Technologies, Inc. System and method for using artificial intelligence and machine learning to provide an enhanced user interface presenting data pertaining to cardiac health, bariatric health, pulmonary health, and/or cardio-oncologic health for the purpose of performing preventative actions
US11317975B2 (en) 2019-10-03 2022-05-03 Rom Technologies, Inc. Method and system for treating patients via telemedicine using sensor data from rehabilitation or exercise equipment
US11101028B2 (en) 2019-10-03 2021-08-24 Rom Technologies, Inc. Method and system using artificial intelligence to monitor user characteristics during a telemedicine session
US12224052B2 (en) 2019-10-03 2025-02-11 Rom Technologies, Inc. System and method for using AI, machine learning and telemedicine for long-term care via an electromechanical machine
US12220201B2 (en) 2019-10-03 2025-02-11 Rom Technologies, Inc. Remote examination through augmented reality
US11282608B2 (en) 2019-10-03 2022-03-22 Rom Technologies, Inc. Method and system for using artificial intelligence and machine learning to provide recommendations to a healthcare provider in or near real-time during a telemedicine session
US12020799B2 (en) 2019-10-03 2024-06-25 Rom Technologies, Inc. Rowing machines, systems including rowing machines, and methods for using rowing machines to perform treatment plans for rehabilitation
US11955222B2 (en) 2019-10-03 2024-04-09 Rom Technologies, Inc. System and method for determining, based on advanced metrics of actual performance of an electromechanical machine, medical procedure eligibility in order to ascertain survivability rates and measures of quality-of-life criteria
US11265234B2 (en) 2019-10-03 2022-03-01 Rom Technologies, Inc. System and method for transmitting data and ordering asynchronous data
US12020800B2 (en) 2019-10-03 2024-06-25 Rom Technologies, Inc. System and method for using AI/ML and telemedicine to integrate rehabilitation for a plurality of comorbid conditions
US12478837B2 (en) 2019-10-03 2025-11-25 Rom Technologies, Inc. Method and system for monitoring actual patient treatment progress using sensor data
US11069436B2 (en) 2019-10-03 2021-07-20 Rom Technologies, Inc. System and method for use of telemedicine-enabled rehabilitative hardware and for encouraging rehabilitative compliance through patient-based virtual shared sessions with patient-enabled mutual encouragement across simulated social networks
US11325005B2 (en) 2019-10-03 2022-05-10 Rom Technologies, Inc. Systems and methods for using machine learning to control an electromechanical device used for prehabilitation, rehabilitation, and/or exercise
US12420143B1 (en) 2019-10-03 2025-09-23 Rom Technologies, Inc. System and method for enabling residentially-based cardiac rehabilitation by using an electromechanical machine and educational content to mitigate risk factors and optimize user behavior
US11955221B2 (en) * 2019-10-03 2024-04-09 Rom Technologies, Inc. System and method for using AI/ML to generate treatment plans to stimulate preferred angiogenesis
US12380984B2 (en) 2019-10-03 2025-08-05 Rom Technologies, Inc. Systems and methods for using artificial intelligence and machine learning to generate treatment plans having dynamically tailored cardiac protocols for users to manage a state of an electromechanical machine
US12469587B2 (en) 2019-10-03 2025-11-11 Rom Technologies, Inc. Systems and methods for assigning healthcare professionals to remotely monitor users performing treatment plans on electromechanical machines
US11915815B2 (en) 2019-10-03 2024-02-27 Rom Technologies, Inc. System and method for using artificial intelligence and machine learning and generic risk factors to improve cardiovascular health such that the need for additional cardiac interventions is mitigated
US12191018B2 (en) 2019-10-03 2025-01-07 Rom Technologies, Inc. System and method for using artificial intelligence in telemedicine-enabled hardware to optimize rehabilitative routines capable of enabling remote rehabilitative compliance
US12062425B2 (en) 2019-10-03 2024-08-13 Rom Technologies, Inc. System and method for implementing a cardiac rehabilitation protocol by using artificial intelligence and standardized measurements
US12548656B2 (en) 2019-10-03 2026-02-10 Rom Technologies, Inc. System and method for an enhanced patient user interface displaying real-time measurement information during a telemedicine session
US12230381B2 (en) 2019-10-03 2025-02-18 Rom Technologies, Inc. System and method for an enhanced healthcare professional user interface displaying measurement information for a plurality of users
US12420145B2 (en) 2019-10-03 2025-09-23 Rom Technologies, Inc. Systems and methods of using artificial intelligence and machine learning for generating alignment plans to align a user with an imaging sensor during a treatment session
US12327623B2 (en) 2019-10-03 2025-06-10 Rom Technologies, Inc. System and method for processing medical claims
US12150792B2 (en) 2019-10-03 2024-11-26 Rom Technologies, Inc. Augmented reality placement of goniometer or other sensors
US11139060B2 (en) 2019-10-03 2021-10-05 Rom Technologies, Inc. Method and system for creating an immersive enhanced reality-driven exercise experience for a user
US11087865B2 (en) 2019-10-03 2021-08-10 Rom Technologies, Inc. System and method for use of treatment device to reduce pain medication dependency
US11282604B2 (en) 2019-10-03 2022-03-22 Rom Technologies, Inc. Method and system for use of telemedicine-enabled rehabilitative equipment for prediction of secondary disease
US11915816B2 (en) 2019-10-03 2024-02-27 Rom Technologies, Inc. Systems and methods of using artificial intelligence and machine learning in a telemedical environment to predict user disease states
US12589279B2 (en) 2019-10-03 2026-03-31 Rom Technologies, Inc. Systems and methods of using artificial intelligence and machine learning for generating an alignment plan capable of enabling the aligning of a user's body during a treatment session
US12230382B2 (en) 2019-10-03 2025-02-18 Rom Technologies, Inc. Systems and methods for using artificial intelligence and machine learning to predict a probability of an undesired medical event occurring during a treatment plan
US20230245750A1 (en) 2019-10-03 2023-08-03 Rom Technologies, Inc. Systems and methods for using elliptical machine to perform cardiovascular rehabilitation
US11826613B2 (en) 2019-10-21 2023-11-28 Rom Technologies, Inc. Persuasive motivation for orthopedic treatment
US12562271B2 (en) 2019-11-06 2026-02-24 Rom Technologies, Inc. System for remote treatment utilizing privacy controls
US12424319B2 (en) 2019-11-06 2025-09-23 Rom Technologies, Inc. System for remote treatment utilizing privacy controls
KR20220110529A (ko) * 2019-12-04 2022-08-08 오메로스 코포레이션 Masp-2 억제자 및 사용 방법
WO2021113698A1 (fr) 2019-12-04 2021-06-10 Omeros Corporation Inhibiteurs de masp-2 et procédés d'utilisation
WO2021113682A1 (fr) 2019-12-04 2021-06-10 Omeros Corporation Inhibiteurs de masp-2 et procédés d'utilisation
KR20220110531A (ko) 2019-12-04 2022-08-08 오메로스 코포레이션 Masp-2 억제자 및 사용 방법
US11107591B1 (en) 2020-04-23 2021-08-31 Rom Technologies, Inc. Method and system for describing and recommending optimal treatment plans in adaptive telemedical or other contexts
WO2021262809A1 (fr) 2020-06-26 2021-12-30 Rom Technologies, Inc. Système, procédé et appareil pour ancrer un dispositif électronique et mesurer un angle d'articulation
KR102846753B1 (ko) 2020-09-04 2025-08-13 주식회사 엘지에너지솔루션 배터리 관리 장치 및 방법
US12367960B2 (en) 2020-09-15 2025-07-22 Rom Technologies, Inc. System and method for using AI ML and telemedicine to perform bariatric rehabilitation via an electromechanical machine
CN114469949A (zh) * 2020-10-27 2022-05-13 正大天晴药业集团股份有限公司 用于治疗弥漫大b细胞淋巴瘤的喹啉衍生物
US12515104B2 (en) 2020-10-28 2026-01-06 Rom Technologies, Inc. Systems and methods for using machine learning to control a rehabilitation and exercise electromechanical device
US20220314072A1 (en) 2021-03-30 2022-10-06 Rehab2Fit Technologies, Inc. Adjustment of exercise based on artificial intelligence, exercise plan, and user feedback
PY22106817A (es) 2021-12-10 2023-12-21 Omeros Corp Anticuerpos terapéuticos que se unen al dominio serina-proteasa de masp-2 y usos de estos
JP2025541737A (ja) 2022-11-30 2025-12-23 オメロス コーポレーション Masp-2阻害物質としての縮合ピリミジン
WO2024226573A2 (fr) * 2023-04-25 2024-10-31 Nuvance Health Méthodes de traitement du cancer dirigé par masp-2
US12216123B2 (en) 2023-04-25 2025-02-04 Nuvance Health Extracellular vesicle derived MASP-2 directed cancer treatment methods
WO2025076476A2 (fr) 2023-10-06 2025-04-10 Omeros Corporation Inhibiteurs de masp-2 et procédés d'utilisation

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331647A (en) 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5453566A (en) 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
AU632993B2 (en) 1987-12-15 1993-01-21 Gene Shears Pty. Limited Ribozymes
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB8822492D0 (en) 1988-09-24 1988-10-26 Considine J Apparatus for removing tumours from hollow organs of body
US5211657A (en) 1988-11-07 1993-05-18 The United States Government As Represented By The Secretary Of The Department Of Health And Human Services Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5549910A (en) 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
SG46445A1 (en) 1990-01-26 1998-02-20 Immunomedics Inc Vaccines against cancer and infectious diseases
JP3218637B2 (ja) 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
US5789573A (en) 1990-08-14 1998-08-04 Isis Pharmaceuticals, Inc. Antisense inhibition of ICAM-1, E-selectin, and CMV IE1/IE2
JP2958076B2 (ja) 1990-08-27 1999-10-06 株式会社ビタミン研究所 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
IL108367A0 (en) 1993-01-27 1994-04-12 Hektoen Inst For Medical Resea Antisense polynzcleotide inhibition of human growth factor-sensitive cancer cells
US5629327A (en) * 1993-03-01 1997-05-13 Childrens Hospital Medical Center Corp. Methods and compositions for inhibition of angiogenesis
US5801154A (en) 1993-10-18 1998-09-01 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of multidrug resistance-associated protein
US5741516A (en) 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US5738868A (en) 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor
US5739119A (en) 1996-11-15 1998-04-14 Galli; Rachel L. Antisense oligonucleotides specific for the muscarinic type 2 acetylcholine receptor MRNA
US6969601B2 (en) * 1997-04-03 2005-11-29 Jensenius Jens Chr MASP-2, a complement-fixing enzyme, and uses for it
US6649592B1 (en) 2000-01-14 2003-11-18 Science & Technology Corporation @ Unm Peptide inhibitors of LFA-1/ICAM-1 interaction
SG98393A1 (en) 2000-05-19 2003-09-19 Inst Materials Research & Eng Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
CA2490007C (fr) 2002-07-19 2011-05-24 Omeros Corporation Copolymeres triblocs biodegradables, procedes de synthese, et hydrogels et biomateriaux fabriques a partir de ces derniers
CN1798769A (zh) 2003-05-12 2006-07-05 内蒂穆恩公司 抗masp-2抗体
US7919094B2 (en) * 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US8840893B2 (en) * 2004-06-10 2014-09-23 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US20130266559A1 (en) * 2004-06-10 2013-10-10 University Of Leicester Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
US11130801B2 (en) * 2011-01-13 2021-09-28 Case Western Reserve University Method for inhibiting platelet derived growth factor signaling with C3aR or C5aR antibodies
CN107638565B (zh) * 2011-04-08 2021-12-21 莱斯特大学 用于治疗与masp-2依赖性补体活化相关的状况的方法
MX361175B (es) 2011-05-04 2018-11-29 Omeros Corp Composiciones para inhibir la activación del complemento dependiente de la masp-2.
EP2723361B1 (fr) * 2011-06-22 2019-10-30 Apellis Pharmaceuticals, Inc. Méthodes de traitement de troubles chroniques au moyen d'inhibiteurs de complément
EP2861246B1 (fr) * 2012-06-18 2021-01-20 Omeros Corporation Compositions et procédés pour l'inhibition de masp-1 et/ou masp-2 et/ou masp-3 pour le traitement de divers troubles et maladies
RS61351B1 (sr) * 2013-10-17 2021-02-26 Omeros Corp Postupci za lečenje stanja udruženih sa aktivacijom komplementa zavisnom od masp-2
JP6369862B2 (ja) 2014-08-06 2018-08-08 原 英彰 眼内血管新生抑制剤及びその用途

Also Published As

Publication number Publication date
KR20200113290A (ko) 2020-10-06
NZ762159A (en) 2025-05-02
CA3096270A1 (fr) 2017-10-05
KR20230019991A (ko) 2023-02-09
GEAP202214913A (en) 2022-09-26
AU2017240129A1 (en) 2018-09-06
MX2022012380A (es) 2022-10-31
CA3018774A1 (fr) 2017-10-05
US11981748B2 (en) 2024-05-14
MX2018011648A (es) 2019-01-30
US20210189009A1 (en) 2021-06-24
JP2020125332A (ja) 2020-08-20
WO2017173290A1 (fr) 2017-10-05
US10870708B2 (en) 2020-12-22
PH12018502046A1 (en) 2019-07-08
CN117582494A (zh) 2024-02-23
BR112018069732A2 (pt) 2019-02-05
KR20250007026A (ko) 2025-01-13
CA3096270C (fr) 2024-05-21
EP3436072A4 (fr) 2019-11-06
KR20180128941A (ko) 2018-12-04
CN109152834A (zh) 2019-01-04
IL305200B1 (en) 2025-11-01
IL305200B2 (en) 2026-03-01
AU2017240129B2 (en) 2020-04-02
EA201892218A1 (ru) 2019-03-29
CA3018774C (fr) 2023-02-28
JP2019513715A (ja) 2019-05-30
PH12018502046B1 (en) 2024-01-24
CL2018002708A1 (es) 2019-01-11
IL262021A (en) 2018-10-31
IL262021B1 (en) 2023-09-01
NZ745531A (en) 2020-09-25
IL262021B2 (en) 2024-01-01
EP3436072A1 (fr) 2019-02-06
SG10202009886SA (en) 2020-11-27
ZA202500956B (en) 2025-06-25
CN115137816A (zh) 2022-10-04
SG11201808242UA (en) 2018-10-30
JP2022110159A (ja) 2022-07-28
IL305200A (en) 2023-10-01
EA202191185A1 (ru) 2021-10-29
AU2020201633B2 (en) 2022-03-31
JP6865767B2 (ja) 2021-04-28
AU2020201633A1 (en) 2020-03-19
US20170283508A1 (en) 2017-10-05
MY195432A (en) 2023-01-20
GEP20237466B (en) 2023-01-25
US20240352152A1 (en) 2024-10-24

Similar Documents

Publication Publication Date Title
EP3436072A4 (fr) Procédés d'inhibition d'angiogenèse chez un sujet qui en a besoin
GB201615395D0 (en) Hose arrangements
EP3529524A4 (fr) Dispositif de déplacement de tuyau d'alimentation en béton à roues
DK3263782T3 (da) Indløbselement
EP3849533A4 (fr) Procédés d'inhibition
UA35584S (uk) Ювелірний виріб «оберіг»
UA33118S (uk) Підвіска «коловрат із зіркою русі»
UA33327S (uk) Ювелірний виріб «оберіг»
IL249690A0 (en) The clean collar sticker
UA31429S (uk) Підвісок «воля віри»
UA33828S (uk) Емблема «мегамастер»
UA34469S (uk) Брошка «шаучам»
UA34208S (uk) Пряжка «драккар»
UA29345S (uk) Логотип «redmond дарите лучшее!»
GB201620142D0 (en) Concept 31
GB201620155D0 (en) Concept 39
UA34203S (uk) Підвіска «зігфрід»
UA32360S (uk) Логотип «f1»
GB201614418D0 (en) Concept 130
GB201613364D0 (en) Concept 118
GB201613340D0 (en) Concept 117
GB201613341D0 (en) Concept 115
GB201613342D0 (en) Concept 116
GB201612833D0 (en) Concept 134
GB201612802D0 (en) Concept 115