MA46205A - Composés 1,2-dithiolane utiles dans la neuroprotection, les maladies et les états auto-immuns et cancéreux - Google Patents
Composés 1,2-dithiolane utiles dans la neuroprotection, les maladies et les états auto-immuns et cancéreuxInfo
- Publication number
- MA46205A MA46205A MA046205A MA46205A MA46205A MA 46205 A MA46205 A MA 46205A MA 046205 A MA046205 A MA 046205A MA 46205 A MA46205 A MA 46205A MA 46205 A MA46205 A MA 46205A
- Authority
- MA
- Morocco
- Prior art keywords
- neuroprotection
- autoimmune
- diseases
- compounds useful
- cancer conditions
- Prior art date
Links
- 150000004864 1,2-dithiolanes Chemical class 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 230000001363 autoimmune Effects 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000004112 neuroprotection Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
- C07C43/29—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662384813P | 2016-09-08 | 2016-09-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46205A true MA46205A (fr) | 2019-07-17 |
Family
ID=61562330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046205A MA46205A (fr) | 2016-09-08 | 2017-09-08 | Composés 1,2-dithiolane utiles dans la neuroprotection, les maladies et les états auto-immuns et cancéreux |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10844038B2 (fr) |
| EP (1) | EP3509599A4 (fr) |
| JP (1) | JP7201586B6 (fr) |
| MA (1) | MA46205A (fr) |
| WO (1) | WO2018049127A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3740491A1 (fr) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Composés de pyrrolo[2,3-d]pyrimidines substitués utilisés en tant qu'inhibiteurs de la kinase ret |
| EP3740486A1 (fr) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Composés de pyrazolyl[4,3-c]pyridine substitués utilisés en tant qu'inhibiteurs de la kinase ret |
| CN111630054B (zh) * | 2018-01-18 | 2023-05-09 | 奥瑞生物药品公司 | 作为RET激酶抑制剂的取代的吡唑并[3,4-d]嘧啶化合物 |
| CA3108065C (fr) | 2018-07-31 | 2025-10-07 | Loxo Oncology, Inc. | Dispersions séchées par pulvérisation, formulations et polymorphies de (s)-5-amino-3-(4-((5 fluoro-2-méthoxybenzamido)méthyle)phényle)(1,1,1-trifluoropropane-2-yl)-1h-pyrazole-4-carboxamide |
| CN109134472B (zh) * | 2018-09-20 | 2020-02-11 | 浙江理工大学 | 一种3-(4-苯氧基苯基)-1H-吡唑并[3,4-d]嘧啶-4-胺的合成工艺 |
| KR20210145773A (ko) | 2019-03-28 | 2021-12-02 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | 티에노헤테로고리형 유도체, 이의 제조 방법 및 이의 의약적 용도 |
| WO2020200069A1 (fr) | 2019-03-29 | 2020-10-08 | 江苏恒瑞医药股份有限公司 | Dérivé pyrrolohétérocyclique, son procédé de préparation et son application en médecine |
| EP3950685A4 (fr) | 2019-04-03 | 2022-12-14 | Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory | Composé de pyrazolopyridine utilisé comme inhibiteur de ret et son application |
| EP3978498A1 (fr) | 2019-05-24 | 2022-04-06 | Jiangsu Hengrui Medicine Co., Ltd. | Dérivé bicyclicque condensé substituté, son procédé de préparation et son application en médecine |
| US20230331731A1 (en) | 2020-09-29 | 2023-10-19 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Crystal form of pyrrolo heterocyclic derivative and preparation method therefor |
| ES3072864T3 (en) * | 2020-09-29 | 2026-07-06 | Guangzhou Baiyunshan Pharmaceutical Holdings Co Ltd Baiyunshan Pharmaceutical General Factory | Crystal forms of pyridopyrazole compounds and preparation method therefor |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993002076A1 (fr) * | 1991-07-18 | 1993-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Compose de 1,2-dithiolane |
| EP2139487B1 (fr) * | 2007-03-28 | 2015-11-11 | Pharmacyclics LLC | Inhibiteurs de la tyrosine kinase de bruton |
| US8242271B2 (en) * | 2007-06-04 | 2012-08-14 | Avila Therapeutics, Inc. | Heterocyclic compounds and uses thereof |
| US8476431B2 (en) * | 2008-11-03 | 2013-07-02 | Itellikine LLC | Benzoxazole kinase inhibitors and methods of use |
| EP3069612A3 (fr) | 2009-06-15 | 2016-10-19 | Encore Health, LLC | Composés dithiols, dérivés et leurs utilisations |
| WO2011141909A2 (fr) * | 2010-05-10 | 2011-11-17 | Radikal Therapeutics Inc. | Dérivés d'acide lipoïque et de nitroxide et leurs utilisations |
| US8377946B1 (en) * | 2011-12-30 | 2013-02-19 | Pharmacyclics, Inc. | Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors |
| WO2014078623A2 (fr) * | 2012-11-15 | 2014-05-22 | Brandeis University | Amarrage de résidus de cystéine à l'aide de bisulfures cycliques |
-
2017
- 2017-09-08 MA MA046205A patent/MA46205A/fr unknown
- 2017-09-08 WO PCT/US2017/050634 patent/WO2018049127A1/fr not_active Ceased
- 2017-09-08 US US16/331,321 patent/US10844038B2/en active Active
- 2017-09-08 JP JP2019513394A patent/JP7201586B6/ja active Active
- 2017-09-08 EP EP17849588.3A patent/EP3509599A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019534857A (ja) | 2019-12-05 |
| US20200010442A1 (en) | 2020-01-09 |
| WO2018049127A1 (fr) | 2018-03-15 |
| JP7201586B2 (ja) | 2023-01-10 |
| US10844038B2 (en) | 2020-11-24 |
| EP3509599A1 (fr) | 2019-07-17 |
| EP3509599A4 (fr) | 2020-02-19 |
| CA3036079A1 (fr) | 2018-03-15 |
| JP7201586B6 (ja) | 2024-02-08 |
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