MA46459A - Méthode de traitement de lésions rénales aiguës - Google Patents

Méthode de traitement de lésions rénales aiguës

Info

Publication number
MA46459A
MA46459A MA046459A MA46459A MA46459A MA 46459 A MA46459 A MA 46459A MA 046459 A MA046459 A MA 046459A MA 46459 A MA46459 A MA 46459A MA 46459 A MA46459 A MA 46459A
Authority
MA
Morocco
Prior art keywords
treatment
acute kidney
kidney damage
acute
damage
Prior art date
Application number
MA046459A
Other languages
English (en)
Other versions
MA46459B1 (fr
Inventor
Bharat Lagu
Michael Patane
Effie Tozzo
Scott Trzaska
Original Assignee
Mitobridge Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitobridge Inc filed Critical Mitobridge Inc
Publication of MA46459A publication Critical patent/MA46459A/fr
Publication of MA46459B1 publication Critical patent/MA46459B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Nutrition Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)

Abstract

La présente invention concerne des procédés de traitement d'un patient humain souffrant d'une lésion rénale aiguë.
MA46459A 2016-10-05 2017-10-05 Méthode de traitement de lésions rénales aiguës MA46459B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662404390P 2016-10-05 2016-10-05
PCT/US2017/055400 WO2018067857A1 (fr) 2016-10-05 2017-10-05 Méthode de traitement de lésions rénales aiguës

Publications (2)

Publication Number Publication Date
MA46459A true MA46459A (fr) 2019-08-14
MA46459B1 MA46459B1 (fr) 2021-03-31

Family

ID=60153507

Family Applications (1)

Application Number Title Priority Date Filing Date
MA46459A MA46459B1 (fr) 2016-10-05 2017-10-05 Méthode de traitement de lésions rénales aiguës

Country Status (33)

Country Link
US (1) US20210283116A1 (fr)
EP (1) EP3522880B1 (fr)
JP (1) JP7065839B2 (fr)
KR (1) KR20190062502A (fr)
CN (1) CN109789117B (fr)
AU (1) AU2017340760B2 (fr)
BR (1) BR112019005539A2 (fr)
CA (1) CA3036723A1 (fr)
CO (1) CO2019004561A2 (fr)
CY (1) CY1124759T1 (fr)
DK (1) DK3522880T3 (fr)
ES (1) ES2859487T3 (fr)
HR (1) HRP20210294T1 (fr)
HU (1) HUE053557T2 (fr)
IL (1) IL265749A (fr)
JO (1) JOP20190056B1 (fr)
LT (1) LT3522880T (fr)
MA (1) MA46459B1 (fr)
MD (1) MD3522880T2 (fr)
MX (1) MX387518B (fr)
MY (1) MY192385A (fr)
PH (1) PH12019500725A1 (fr)
PL (1) PL3522880T3 (fr)
PT (1) PT3522880T (fr)
RS (1) RS61573B1 (fr)
RU (1) RU2753607C2 (fr)
SG (1) SG11201901925RA (fr)
SI (1) SI3522880T1 (fr)
SM (1) SMT202100111T1 (fr)
TW (1) TWI778982B (fr)
UA (1) UA124019C2 (fr)
WO (1) WO2018067857A1 (fr)
ZA (1) ZA201901743B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016333963C1 (en) 2015-10-07 2021-05-27 The Salk Institute For Biological Studies PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
US11358954B2 (en) * 2016-04-13 2022-06-14 Mitobridge, Inc. PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
CN109843857B (zh) * 2016-10-05 2023-01-06 米托布里奇公司 Ppar激动剂化合物的结晶和盐形式
WO2021013772A1 (fr) 2019-07-19 2021-01-28 Vifor (International) Ag Inhibiteurs de ferroportine destinés à être utilisés dans la prévention et le traitement de lésions rénales
US11634387B2 (en) 2019-09-26 2023-04-25 Abionyx Pharma Sa Compounds useful for treating liver diseases
CA3212825A1 (fr) * 2021-03-08 2022-09-15 Abionyx Pharma Sa Composes utiles pour le traitement des maladies du foie
WO2022189856A1 (fr) 2021-03-08 2022-09-15 Abionyx Pharma Sa Composés utiles pour le traitement des maladies du foie
CN115813901B (zh) * 2022-10-20 2024-10-22 南京市儿童医院 3-苯基戊二酸衍生物类小分子在制备防治顺铂诱导的急性肾损伤药物中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2539403C (fr) 2003-09-19 2013-11-19 Janssen Pharmaceutica N.V. Acides 4-((phenoxyalkyl)thio)-phenoxyacetiques et analogues
RU2006145872A (ru) * 2004-05-25 2008-06-27 Метаболекс, Инк. (Us) Замещенные триазолы в качестве модуляторов ppar и способы их получения
RU2320341C1 (ru) * 2006-06-13 2008-03-27 Государственное учреждение Научный центр реконструктивной и восстановительной хирургии Восточно-Сибирского научного центра Сибирского отделения Российской Академии медицинских наук Средство для лечения острой обструкции верхних мочевыводящих путей
KR20090071829A (ko) * 2007-12-28 2009-07-02 주식회사 머젠스 신장질환의 치료 및 예방을 위한 약제 조성물
JP5694941B2 (ja) 2008-10-17 2015-04-01 シーマベイ セラピューティクス,インコーポレイティド 小型高密度ldl粒子を減少させる方法
US7928067B2 (en) * 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
JP2016512201A (ja) 2013-03-08 2016-04-25 アッヴィ・インコーポレイテッド 急性腎障害の治療方法
JP2016520552A (ja) * 2013-04-05 2016-07-14 ソーク インスティテュート フォー バイオロジカル スタディーズ Pparアゴニスト
EP2862574A1 (fr) 2013-10-15 2015-04-22 Sanofi Acide {4-[5-(3-chloro-phénoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-diméthyl-phénoxy}-acétique pour son utilisation dans la prévention ou le traitement de l'insuffisance rénale aiguë
CN110007084B (zh) * 2013-12-03 2022-11-18 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
US20170305894A1 (en) * 2014-10-08 2017-10-26 Mitobridge, Inc. Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof
WO2016057656A1 (fr) * 2014-10-08 2016-04-14 Mitobridge, Inc. Agonistes ppar-delta destinés à être utilisés pour le traitement d'affections mitochondriales, vasculaires, musculaires et démyélynisantes
AU2016333963C1 (en) * 2015-10-07 2021-05-27 The Salk Institute For Biological Studies PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof

Also Published As

Publication number Publication date
AU2017340760A1 (en) 2019-03-21
PL3522880T3 (pl) 2021-08-23
CY1124759T1 (el) 2022-07-22
ES2859487T3 (es) 2021-10-04
RU2019111421A (ru) 2020-11-06
JP2019533660A (ja) 2019-11-21
ZA201901743B (en) 2022-04-28
MA46459B1 (fr) 2021-03-31
AU2017340760B2 (en) 2023-07-27
MY192385A (en) 2022-08-18
MX2019003949A (es) 2019-06-10
PT3522880T (pt) 2021-02-22
RS61573B1 (sr) 2021-04-29
SG11201901925RA (en) 2019-04-29
JOP20190056A1 (ar) 2019-03-24
CN109789117A (zh) 2019-05-21
RU2019111421A3 (fr) 2021-02-05
UA124019C2 (uk) 2021-07-07
EP3522880B1 (fr) 2020-12-02
WO2018067857A1 (fr) 2018-04-12
TWI778982B (zh) 2022-10-01
MD3522880T2 (ro) 2021-03-31
PH12019500725A1 (en) 2019-08-05
SMT202100111T1 (it) 2021-05-07
LT3522880T (lt) 2021-03-25
DK3522880T3 (en) 2021-01-18
TW201815391A (zh) 2018-05-01
MX387518B (es) 2025-03-18
RU2753607C2 (ru) 2021-08-18
CO2019004561A2 (es) 2019-07-31
KR20190062502A (ko) 2019-06-05
CN109789117B (zh) 2022-08-23
JP7065839B2 (ja) 2022-05-12
BR112019005539A2 (pt) 2019-06-18
SI3522880T1 (sl) 2021-07-30
JOP20190056B1 (ar) 2022-03-15
IL265749A (en) 2019-06-30
HRP20210294T1 (hr) 2021-04-16
HUE053557T2 (hu) 2021-07-28
EP3522880A1 (fr) 2019-08-14
CA3036723A1 (fr) 2018-04-12
US20210283116A1 (en) 2021-09-16

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