MA46568A - Dosage biologique de formulations d'insuline - Google Patents
Dosage biologique de formulations d'insulineInfo
- Publication number
- MA46568A MA46568A MA046568A MA46568A MA46568A MA 46568 A MA46568 A MA 46568A MA 046568 A MA046568 A MA 046568A MA 46568 A MA46568 A MA 46568A MA 46568 A MA46568 A MA 46568A
- Authority
- MA
- Morocco
- Prior art keywords
- insulin formulations
- biological dosage
- dosage
- biological
- insulin
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/62—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16195387 | 2016-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46568A true MA46568A (fr) | 2019-08-28 |
Family
ID=57208127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046568A MA46568A (fr) | 2016-10-24 | 2017-10-24 | Dosage biologique de formulations d'insuline |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10914728B2 (fr) |
| EP (1) | EP3529615A1 (fr) |
| JP (1) | JP7022746B2 (fr) |
| CN (1) | CN109891237B (fr) |
| MA (1) | MA46568A (fr) |
| WO (1) | WO2018077851A1 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210371489A1 (en) * | 2018-09-21 | 2021-12-02 | Case Western Reserve University | Site 2 single-chain insulin analogues |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2136595T5 (es) | 1989-04-19 | 2004-04-01 | Enzon, Inc. | Carbonatos activos de oxidos de polialquileno para la modificacion de polipeptidos. |
| US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| JP2000502097A (ja) | 1995-12-20 | 2000-02-22 | メディカル、リサーチ、カウンシル | タンパク質合成の制御、および作用薬のスクリーニング法 |
| GB0007915D0 (en) | 2000-03-31 | 2000-05-17 | Univ Bristol | Protein kinase assay |
| AU2003223495A1 (en) | 2002-04-05 | 2003-10-27 | Cell Signaling Technology, Inc. | Molecular profiling of disease and therapeutic response using phospho-specific antibodies |
| JP2005528921A (ja) | 2002-06-10 | 2005-09-29 | メタボレックス インコーポレーティッド | Cx3cr1修飾物質を用いる糖尿病の治療および診断の方法 |
| US7220539B1 (en) | 2002-06-12 | 2007-05-22 | The Salk Institute For Biological Studies | Protein kinase B/Akt modulators and methods for the use thereof |
| US20050014682A1 (en) * | 2003-07-16 | 2005-01-20 | Mike Mueckler | Cell-free assay for insulin signaling |
| GB0328157D0 (en) * | 2003-12-04 | 2004-01-07 | Imp College Innovations Ltd | Compounds |
| US20080207490A1 (en) | 2005-07-07 | 2008-08-28 | Postech Foundation | Glucose Uptake Modulator and Method for Treating Diabetes or Diabetic Complications |
| RU2524150C2 (ru) * | 2006-09-22 | 2014-07-27 | Ново Нордиск А/С | Аналоги инсулина, устойчивые к протеазам |
| HUE032284T2 (en) | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| WO2010139075A1 (fr) | 2009-06-05 | 2010-12-09 | Mcmaster University | Synthèse et utilisation d'analogues d'insuline radiomarqués |
| US8926976B2 (en) | 2009-09-25 | 2015-01-06 | Xoma Technology Ltd. | Modulators |
| EA027744B1 (ru) | 2011-10-31 | 2017-08-31 | Ксерис Фармасьютикалс, Инк. | Лекарственные формы для лечения сахарного диабета |
| WO2014093696A2 (fr) | 2012-12-12 | 2014-06-19 | Massachusetts Institute Of Technology | Dérivés d'insuline pour le traitement du diabète |
| BR112015023672A2 (pt) | 2013-03-15 | 2017-07-18 | Univ Case Western Reserve | análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina. |
| CN105392475A (zh) | 2013-07-24 | 2016-03-09 | 诺和诺德股份有限公司 | 包含片剂核和阴离子共聚物涂层的用于口服胰岛素给药的药学组合物 |
| TN2017000178A1 (en) * | 2014-11-21 | 2018-10-19 | Merck Sharp & Dohme | Insulin receptor partial agonists |
-
2017
- 2017-10-24 MA MA046568A patent/MA46568A/fr unknown
- 2017-10-24 EP EP17794930.2A patent/EP3529615A1/fr not_active Withdrawn
- 2017-10-24 US US16/335,060 patent/US10914728B2/en not_active Expired - Fee Related
- 2017-10-24 JP JP2019521689A patent/JP7022746B2/ja not_active Expired - Fee Related
- 2017-10-24 WO PCT/EP2017/077120 patent/WO2018077851A1/fr not_active Ceased
- 2017-10-24 CN CN201780065928.XA patent/CN109891237B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP7022746B2 (ja) | 2022-02-18 |
| WO2018077851A1 (fr) | 2018-05-03 |
| US20190361007A1 (en) | 2019-11-28 |
| EP3529615A1 (fr) | 2019-08-28 |
| CN109891237A (zh) | 2019-06-14 |
| CN109891237B (zh) | 2022-08-23 |
| JP2020502489A (ja) | 2020-01-23 |
| US10914728B2 (en) | 2021-02-09 |
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