MA46570A - Procédés et compositions pharmaceutiques permettant de favoriser la réaction des lymphocytes t - Google Patents

Procédés et compositions pharmaceutiques permettant de favoriser la réaction des lymphocytes t

Info

Publication number
MA46570A
MA46570A MA046570A MA46570A MA46570A MA 46570 A MA46570 A MA 46570A MA 046570 A MA046570 A MA 046570A MA 46570 A MA46570 A MA 46570A MA 46570 A MA46570 A MA 46570A
Authority
MA
Morocco
Prior art keywords
promoting
compositions
pharmaceutical processes
lymphocytes reaction
lymphocytes
Prior art date
Application number
MA046570A
Other languages
English (en)
Other versions
MA46570B1 (fr
Inventor
Elise Chiffoleau
Vanessa Gauttier
Nicolas Poirier
Géraldine TEPPAZ
Bernard Vanhove
Original Assignee
Inst Nat Sante Rech Med
Ose Immunotherapeutics
Univ Nantes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Ose Immunotherapeutics, Univ Nantes filed Critical Inst Nat Sante Rech Med
Publication of MA46570A publication Critical patent/MA46570A/fr
Publication of MA46570B1 publication Critical patent/MA46570B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726Lectins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1732Lectins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA46570A 2016-10-21 2017-10-20 Procédés et compositions pharmaceutiques permettant de favoriser la réaction des lymphocytes t MA46570B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16306381 2016-10-21
EP17305988 2017-07-24
PCT/EP2017/076911 WO2018073440A1 (fr) 2016-10-21 2017-10-20 Procédés pour favoriser la réponse des lymphocytes t

Publications (2)

Publication Number Publication Date
MA46570A true MA46570A (fr) 2021-03-31
MA46570B1 MA46570B1 (fr) 2021-10-29

Family

ID=60293924

Family Applications (1)

Application Number Title Priority Date Filing Date
MA46570A MA46570B1 (fr) 2016-10-21 2017-10-20 Procédés et compositions pharmaceutiques permettant de favoriser la réaction des lymphocytes t

Country Status (21)

Country Link
US (3) US11365257B2 (fr)
EP (2) EP3529262B1 (fr)
JP (2) JP7032396B6 (fr)
KR (1) KR102646708B1 (fr)
CN (1) CN110291102A (fr)
AU (1) AU2017345286B2 (fr)
CA (1) CA3039348C (fr)
CY (1) CY1124584T1 (fr)
DK (1) DK3529262T3 (fr)
ES (2) ES2978486T3 (fr)
HR (1) HRP20211544T1 (fr)
HU (1) HUE056016T2 (fr)
IL (1) IL266111B (fr)
LT (1) LT3529262T (fr)
MA (1) MA46570B1 (fr)
MD (1) MD3529262T2 (fr)
PL (1) PL3529262T3 (fr)
RS (1) RS62463B1 (fr)
SI (1) SI3529262T1 (fr)
SM (1) SMT202100555T1 (fr)
WO (1) WO2018073440A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3529262T1 (sl) * 2016-10-21 2021-12-31 Inserm - Institut National De La Sante Et De La Recherche Medicale Postopki za spodbujanje odgovora T-celic
RU2019130504A (ru) 2017-02-28 2021-03-30 Вор Байофарма, Инк. Композиции и способы ингибирования линиеспецифических белков
CA3110837A1 (fr) 2018-08-28 2020-03-05 Vor Biopharma Inc. Cellules souches hematopoietiques genetiquement modifiees et utilisations associees
EP4069372A1 (fr) 2019-12-05 2022-10-12 Ose Immunotherapeutics Anticorps anti-clec-1 a et fragment de liaison à l'antigène de ceux-ci
CN113156140A (zh) * 2021-03-05 2021-07-23 青岛大学附属医院 C型凝集素样受体-1作为真菌性角膜炎的治疗标志物的应用
IL309107A (en) * 2021-06-08 2024-02-01 Ose Immunotherapeutics Humanized antibodies against CLEC-1A, antigen-binding fragments thereof and their mimetics
CN118510534A (zh) * 2021-11-09 2024-08-16 Ose免疫疗法 Clec-1配体的识别及其用途
JP2025525884A (ja) 2022-08-01 2025-08-07 オーエスイー・イミュノセラピューティクス ヘテロ二量体Fc-CLEC-1融合分子及びその使用
WO2025032213A1 (fr) 2023-08-10 2025-02-13 Ose Immunotherapeutics Identification d'hla-dra en tant que ligand de clec-1 et ses utilisations

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5567610A (en) 1986-09-04 1996-10-22 Bioinvent International Ab Method of producing human monoclonal antibodies and kit therefor
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5175384A (en) 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5229275A (en) 1990-04-26 1993-07-20 Akzo N.V. In-vitro method for producing antigen-specific human monoclonal antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
DK1621554T4 (da) 1992-08-21 2012-12-17 Univ Bruxelles Immunoglobuliner blottet for lette kæder
US5618829A (en) 1993-01-28 1997-04-08 Mitsubishi Chemical Corporation Tyrosine kinase inhibitors and benzoylacrylamide derivatives
ATE361759T1 (de) 1993-07-15 2007-06-15 Cancer Res Campaign Tech Verbindungen die zur herstellung von protein- tyrosin-kinase-inhibitor-prodrogen verwendet werden können
EP0690452A3 (fr) 1994-06-28 1999-01-07 Advanced Micro Devices, Inc. Mémoire électriquement effaçable et procédé d'effacement
US5804396A (en) 1994-10-12 1998-09-08 Sugen, Inc. Assay for agents active in proliferative disorders
EP0739981A1 (fr) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Fragments variables d'immunoglobulines-utilisation thérapeutique ou vétérinaire
US5639757A (en) 1995-05-23 1997-06-17 Pfizer Inc. 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors
EA001595B1 (ru) 1996-04-12 2001-06-25 Варнер-Ламберт Компани Необратимые ингибиторы тирозинкиназ
ZA986732B (en) 1997-07-29 1999-02-02 Warner Lambert Co Irreversible inhibitiors of tyrosine kinases
US6100254A (en) 1997-10-10 2000-08-08 Board Of Regents, The University Of Texas System Inhibitors of protein tyrosine kinases
US6740665B1 (en) 1999-02-10 2004-05-25 Ramachandran Murali Tyrosine kinase inhibitors and methods of using the same
US6245759B1 (en) 1999-03-11 2001-06-12 Merck & Co., Inc. Tyrosine kinase inhibitors
EP1194152A4 (fr) 1999-06-30 2002-11-06 Merck & Co Inc Composes inhibiteurs de la kinase src
EP1206260A4 (fr) 1999-06-30 2002-10-30 Merck & Co Inc Composes inhibiteurs de la src kinase
WO2001000213A1 (fr) 1999-06-30 2001-01-04 Merck & Co., Inc. Composes inhibiteurs de la src kinase
AU779908B2 (en) 1999-09-10 2005-02-17 Merck & Co., Inc. Tyrosine kinase inhibitors
CA2387351C (fr) 1999-10-19 2009-09-08 Merck & Co., Inc. Derives d'indole servant d'inhibiteurs de la tyrosine kinase
US6794393B1 (en) 1999-10-19 2004-09-21 Merck & Co., Inc. Tyrosine kinase inhibitors
AU778042B2 (en) 1999-10-19 2004-11-11 Merck & Co., Inc. Tyrosine kinase inhibitors
CN1454215B (zh) * 1999-11-15 2013-01-02 米勒腾尼生物技术有限公司 树突状细胞特异的抗原结合片段、组合物及其使用方法、被其识别的抗原及由其获得的细胞
US6313138B1 (en) 2000-02-25 2001-11-06 Merck & Co., Inc. Tyrosine kinase inhibitors
US6420382B2 (en) 2000-02-25 2002-07-16 Merck & Co., Inc. Tyrosine kinase inhibitors
CA2450562A1 (fr) 2001-06-22 2003-01-03 Merck & Co., Inc. Inhibiteurs de tyrosine kinase
US6958340B2 (en) 2001-08-01 2005-10-25 Merck & Co., Inc. Tyrosine kinase inhibitors
US6927293B2 (en) 2001-08-30 2005-08-09 Merck & Co., Inc. Tyrosine kinase inhibitors
US8246959B1 (en) * 2003-08-01 2012-08-21 University Of Washington Dendritic cell-associated lectin-like molecules, compositions and methods of use
WO2007109571A2 (fr) 2006-03-17 2007-09-27 Prometheus Laboratories, Inc. Procédés de prédiction et de suivi de la thérapie par l'inhibiteur de la tyrosine kinase
NZ595319A (en) * 2007-02-23 2012-09-28 Baylor Res Inst Activation of human antigen-presenting cells through clec-6
WO2011105424A1 (fr) * 2010-02-23 2011-09-01 国立大学法人東京大学 Stimulant d'immunorécepteur de cellules dendritiques
SG10201913782UA (en) * 2014-07-21 2020-03-30 Novartis Ag Treatment of cancer using a cll-1 chimeric antigen receptor
SI3529262T1 (sl) 2016-10-21 2021-12-31 Inserm - Institut National De La Sante Et De La Recherche Medicale Postopki za spodbujanje odgovora T-celic

Also Published As

Publication number Publication date
US12091464B2 (en) 2024-09-17
EP3950709A1 (fr) 2022-02-09
SI3529262T1 (sl) 2021-12-31
CY1124584T1 (el) 2022-07-22
PL3529262T3 (pl) 2021-12-27
US20190309075A1 (en) 2019-10-10
EP3529262B1 (fr) 2021-07-21
US20220281983A1 (en) 2022-09-08
HUE056016T2 (hu) 2022-01-28
WO2018073440A1 (fr) 2018-04-26
AU2017345286B2 (en) 2023-08-03
CN110291102A (zh) 2019-09-27
KR20190068605A (ko) 2019-06-18
AU2017345286A1 (en) 2019-04-18
CA3039348C (fr) 2023-09-05
DK3529262T3 (da) 2021-09-20
EP3950709B1 (fr) 2024-02-14
IL266111B (en) 2022-09-01
HRP20211544T1 (hr) 2022-01-07
RS62463B1 (sr) 2021-11-30
LT3529262T (lt) 2021-11-10
US11365257B2 (en) 2022-06-21
EP3529262A1 (fr) 2019-08-28
ES2883678T3 (es) 2021-12-09
JP2020503252A (ja) 2020-01-30
IL266111A (en) 2019-06-30
US20240400695A1 (en) 2024-12-05
ES2978486T3 (es) 2024-09-13
SMT202100555T1 (it) 2021-11-12
MD3529262T2 (ro) 2022-01-31
MA46570B1 (fr) 2021-10-29
JP7032396B6 (ja) 2022-03-22
JP7032396B2 (ja) 2022-03-08
JP7404418B6 (ja) 2024-01-26
JP2022065159A (ja) 2022-04-26
JP7404418B2 (ja) 2023-12-25
KR102646708B1 (ko) 2024-03-12
CA3039348A1 (fr) 2018-04-26

Similar Documents

Publication Publication Date Title
MA46570A (fr) Procédés et compositions pharmaceutiques permettant de favoriser la réaction des lymphocytes t
EP3706784A4 (fr) Compositions et procédés de production de lymphocytes t
EP3436482A4 (fr) Anticorps, compositions pharmaceutiques et procédés
EP3562510A4 (fr) Molécules de peg ramifié, compositions et procédés associés
EP3697588A4 (fr) Procédés et appareils de coulage de produits polymères
EP3303413A4 (fr) Procédés de préparation de sugammadex et de ses intermédiaires
EP3397260A4 (fr) Procédés et compositions se rapportant à des chondrisomes provenant de produits sanguins
MA41558A (fr) Compositions d'allergènes mélangés et leurs procédés d'utilisation
EP3302507A4 (fr) Procédés de diagnostic pour thérapie par lymphocytes t
EP3389672A4 (fr) Compositions et procédés de traitement de maladies hépatiques
EP3302804A4 (fr) Porte-échantillon et système de dosage permettant de provoquer des réactions indiquées
EP3273944A4 (fr) Compositions et procédés permettant d'administrer des agents de type biomacromolécule
EP3359693A4 (fr) Procédés et compositions pour enrichissement de produits d'amplification
EP3478658A4 (fr) Compositions pharmaceutiques et procédés de potentialisation du silençage génique
EP3341392A4 (fr) Compositions et procédés de traitement de la douleur
PL3274469T3 (pl) Kompozycje i sposoby wykrywania zanieczyszczenia biologicznego
EP3247190A4 (fr) Système de dosage pour matière particulaire solide
MA45154A (fr) Procédés de préparation d'oligomères
EP3606465A4 (fr) Schémas posologiques et compositions et procédés associés
EP3528787A4 (fr) Formulations pharmaceutiques et leurs procédés de préparation
MA45861A (fr) Catalyseurs, procédés et produits réactionnels associés
EP3423404A4 (fr) Nouvelles compositions de germanosilicates et procédés de préparation de celles-ci
EP3433383A4 (fr) Procédés d'amplification quantitative
EP3606929A4 (fr) Nucléotides d'ester de bêta-nicotinate et leurs procédés de préparation
EP3302248A4 (fr) Appareil de confirmation de dosage