MA47605A - Procédés de purification d'arn messager - Google Patents
Procédés de purification d'arn messagerInfo
- Publication number
- MA47605A MA47605A MA047605A MA47605A MA47605A MA 47605 A MA47605 A MA 47605A MA 047605 A MA047605 A MA 047605A MA 47605 A MA47605 A MA 47605A MA 47605 A MA47605 A MA 47605A
- Authority
- MA
- Morocco
- Prior art keywords
- messenger rna
- purification processes
- rna purification
- processes
- messenger
- Prior art date
Links
- 238000000746 purification Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/10—Characterised by chemical treatment
- C12Q2523/113—Denaturating agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/30—Characterised by physical treatment
- C12Q2523/308—Adsorption or desorption
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/03—Carboxy- and carbamoyltransferases (2.1.3)
- C12Y201/03003—Ornithine carbamoyltransferase (2.1.3.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463998P | 2017-02-27 | 2017-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA47605A true MA47605A (fr) | 2020-01-01 |
Family
ID=61628474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA047605A MA47605A (fr) | 2017-02-27 | 2018-02-27 | Procédés de purification d'arn messager |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10808241B2 (fr) |
| EP (2) | EP3585891B1 (fr) |
| AU (1) | AU2018224843B2 (fr) |
| CA (1) | CA3054321A1 (fr) |
| CY (1) | CY1124735T1 (fr) |
| DK (1) | DK3585891T3 (fr) |
| ES (1) | ES2899323T3 (fr) |
| HU (1) | HUE059025T2 (fr) |
| IL (1) | IL268857B2 (fr) |
| MA (1) | MA47605A (fr) |
| WO (1) | WO2018157133A1 (fr) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3998064A1 (fr) | 2011-06-08 | 2022-05-18 | Translate Bio, Inc. | Lipides clivables |
| KR20150128687A (ko) | 2013-03-14 | 2015-11-18 | 샤이어 휴먼 지네틱 테라피즈 인크. | 메신저 rna의 정제 방법 |
| WO2018157133A1 (fr) * | 2017-02-27 | 2018-08-30 | Translate Bio, Inc. | Procédés de purification d'arn messager |
| JP7423522B2 (ja) | 2017-11-22 | 2024-01-29 | モダーナティエックス・インコーポレイテッド | 尿素サイクル異常症の治療のためのオルニチントランスカルバミラーゼをコードするポリヌクレオチド |
| EP3793689A1 (fr) * | 2018-05-15 | 2021-03-24 | Translate Bio, Inc. | Administration sous-cutanée d'arn messager |
| WO2020041793A1 (fr) * | 2018-08-24 | 2020-02-27 | Translate Bio, Inc. | Procédés de purification d'arn messager |
| AU2019376004B2 (en) * | 2018-11-08 | 2025-12-18 | Translate Bio, Inc. | Methods and compositions for messenger RNA purification |
| CN113396219A (zh) | 2019-02-11 | 2021-09-14 | 埃泽瑞斯公司 | 通过切向流过滤纯化mRNA |
| CA3139679A1 (fr) * | 2019-05-15 | 2020-11-19 | Translate Bio, Inc. | Procedes de purification d'arn messager |
| IL294073A (en) | 2019-12-20 | 2022-08-01 | Translate Bio Inc | Rectal administration of messenger rna |
| WO2021127641A1 (fr) | 2019-12-20 | 2021-06-24 | Translate Bio, Inc. | Procédé amélioré de préparation de nanoparticules lipidiques chargées d'arnm |
| EP4103712A1 (fr) | 2020-02-10 | 2022-12-21 | Translate Bio, Inc. | Procédés et compositions pour purification d'arn messager |
| US11969480B2 (en) | 2020-02-25 | 2024-04-30 | Translate Bio, Inc. | Processes of preparing mRNA-loaded lipid nanoparticles |
| EP4146680A1 (fr) | 2020-05-07 | 2023-03-15 | Translate Bio, Inc. | Composition et méthodes de traitement d'une dyskinésie ciliaire primitive |
| WO2021226436A1 (fr) | 2020-05-07 | 2021-11-11 | Translate Bio, Inc. | Séquences nucléotidiques optimisées codant pour des antigènes du sras-cov-2 |
| WO2021231901A1 (fr) | 2020-05-15 | 2021-11-18 | Translate Bio, Inc. | Formulations de nanoparticules lipidiques pour l'administration d'arnm |
| JP2023544167A (ja) * | 2020-10-01 | 2023-10-20 | トランスレイト バイオ， インコーポレイテッド | メッセンジャーｒｎａの精製のための方法 |
| JP2023544197A (ja) | 2020-10-06 | 2023-10-20 | トランスレイト バイオ， インコーポレイテッド | 脂質ナノ粒子の改善された方法および製剤 |
| US20220133631A1 (en) | 2020-10-12 | 2022-05-05 | Translate Bio, Inc. | Process of preparing ice-based lipid nanoparticles |
| WO2022081544A1 (fr) | 2020-10-12 | 2022-04-21 | Translate Bio, Inc. | Procédé amélioré de préparation de nanoparticules lipidiques chargées d'arnm |
| EP4229208A4 (fr) | 2020-10-14 | 2024-10-30 | George Mason Research Foundation, Inc. | Méthodes de fabrication de nanoparticules lipidiques et compositions dérivées de celles-ci |
| AU2021373892A1 (en) | 2020-11-09 | 2023-07-06 | Translate Bio, Inc. | Improved compositions for delivery of codon-optimized mrna |
| US20250268994A1 (en) | 2021-03-25 | 2025-08-28 | Translate Bio, Inc. | Optimized Nucleotide Sequences Encoding the Extracellular Domain of Human ACE2 Protein or a Portion Thereof |
| JP2024515668A (ja) | 2021-04-19 | 2024-04-10 | トランスレイト バイオ， インコーポレイテッド | Ｍｒｎａの送達のための改善された組成物 |
| EP4362920A1 (fr) | 2021-07-01 | 2024-05-08 | Translate Bio, Inc. | Compositions de livraison d'arnm |
| WO2023086893A1 (fr) | 2021-11-10 | 2023-05-19 | Translate Bio, Inc. | Composition et méthodes de traitement de la dyskinésie ciliaire primitive |
| IL318619A (en) | 2022-07-29 | 2025-03-01 | Sanofi Pasteur Inc | Methods for ethanol-free purification of mRNA |
| WO2024083345A1 (fr) | 2022-10-21 | 2024-04-25 | BioNTech SE | Procédés et utilisations associés à des compositions liquides |
| WO2024112652A1 (fr) | 2022-11-21 | 2024-05-30 | Translate Bio, Inc. | Compositions de formulations de poudre sèche d'arn messager et leurs procédés d'utilisation |
| AU2023394992A1 (en) | 2022-12-15 | 2025-07-31 | Sanofi Pasteur Inc. | Mrna encoding influenza virus-like particle |
| AR131438A1 (es) | 2022-12-20 | 2025-03-19 | Sanofi Sa | VACUNA DE ARNm DE RINOVIRUS |
| WO2024133884A2 (fr) | 2022-12-23 | 2024-06-27 | Sanofi | Queue optimisée d'arn messager |
| WO2024184489A1 (fr) | 2023-03-07 | 2024-09-12 | Sanofi | Fabrication d'arn messager avec kp34 polymérase |
| WO2024194767A1 (fr) | 2023-03-17 | 2024-09-26 | BioNTech SE | Système automatisé de production de médicament |
| EP4698156A1 (fr) | 2023-04-17 | 2026-02-25 | Sanofi Pasteur Inc. | Formulations de poudre sèche reconstituables et leurs procédés d'utilisation |
| WO2025017151A1 (fr) | 2023-07-18 | 2025-01-23 | Sanofi | Matrices d'arn messager codant pour le poly(a) stables |
| WO2025104351A1 (fr) | 2023-11-17 | 2025-05-22 | Sanofi Pasteur Inc. | Dosages par clhp pour détecter de multiples constructions d'arnm |
| WO2025141200A1 (fr) | 2023-12-29 | 2025-07-03 | Sanofi Pasteur Inc. | Arn polymérases modifiées |
| WO2026033123A1 (fr) | 2024-08-08 | 2026-02-12 | Sanofi Pasteur Inc. | Formulations de nanoparticules lipidiques pour l'administration d'arnm |
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| KR102739894B1 (ko) | 2014-04-25 | 2024-12-05 | 샤이어 휴먼 지네틱 테라피즈 인크. | 메신저 rna 의 정제 방법 |
| US10022455B2 (en) | 2014-05-30 | 2018-07-17 | Translate Bio, Inc. | Biodegradable lipids for delivery of nucleic acids |
| AU2015279968B2 (en) | 2014-06-24 | 2019-11-14 | Translate Bio, Inc. | Stereochemically enriched compositions for delivery of nucleic acids |
| CN106456547B (zh) | 2014-07-02 | 2021-11-12 | 川斯勒佰尔公司 | 信使rna的包封 |
| US10172924B2 (en) | 2015-03-19 | 2019-01-08 | Translate Bio, Inc. | MRNA therapy for pompe disease |
| KR101693166B1 (ko) | 2016-07-12 | 2017-01-06 | 정수영 | 분말 액체 혼합물용 누체 여과 건조 장치 |
| WO2018157133A1 (fr) * | 2017-02-27 | 2018-08-30 | Translate Bio, Inc. | Procédés de purification d'arn messager |
| EP3784284B1 (fr) | 2018-04-25 | 2023-08-02 | Ethris GmbH | Formulations a base de lipides pour la delivrance d'arn |
-
2018
- 2018-02-27 WO PCT/US2018/019954 patent/WO2018157133A1/fr not_active Ceased
- 2018-02-27 IL IL268857A patent/IL268857B2/en unknown
- 2018-02-27 MA MA047605A patent/MA47605A/fr unknown
- 2018-02-27 ES ES18711201T patent/ES2899323T3/es active Active
- 2018-02-27 DK DK18711201.6T patent/DK3585891T3/da active
- 2018-02-27 EP EP18711201.6A patent/EP3585891B1/fr active Active
- 2018-02-27 US US15/906,864 patent/US10808241B2/en active Active
- 2018-02-27 EP EP21204742.7A patent/EP3971291A1/fr not_active Withdrawn
- 2018-02-27 HU HUE18711201A patent/HUE059025T2/hu unknown
- 2018-02-27 AU AU2018224843A patent/AU2018224843B2/en active Active
- 2018-02-27 CA CA3054321A patent/CA3054321A1/fr active Pending
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2020
- 2020-10-14 US US17/070,877 patent/US11976272B2/en active Active
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2021
- 2021-11-18 CY CY20211101004T patent/CY1124735T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3585891B1 (fr) | 2021-10-27 |
| CY1124735T1 (el) | 2022-07-22 |
| WO2018157133A1 (fr) | 2018-08-30 |
| US10808241B2 (en) | 2020-10-20 |
| US20210123041A1 (en) | 2021-04-29 |
| IL268857B1 (en) | 2024-05-01 |
| DK3585891T3 (da) | 2021-11-22 |
| IL268857A (en) | 2019-10-31 |
| US20180251755A1 (en) | 2018-09-06 |
| EP3585891A1 (fr) | 2020-01-01 |
| AU2018224843A1 (en) | 2019-09-19 |
| ES2899323T3 (es) | 2022-03-10 |
| EP3971291A1 (fr) | 2022-03-23 |
| AU2018224843B2 (en) | 2024-08-15 |
| HUE059025T2 (hu) | 2022-10-28 |
| IL268857B2 (en) | 2024-09-01 |
| US11976272B2 (en) | 2024-05-07 |
| CA3054321A1 (fr) | 2018-08-30 |
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