MA44732A - Procédés de production d'arn simple brin - Google Patents
Procédés de production d'arn simple brinInfo
- Publication number
- MA44732A MA44732A MA044732A MA44732A MA44732A MA 44732 A MA44732 A MA 44732A MA 044732 A MA044732 A MA 044732A MA 44732 A MA44732 A MA 44732A MA 44732 A MA44732 A MA 44732A
- Authority
- MA
- Morocco
- Prior art keywords
- single strand
- production processes
- strand rna
- rna production
- processes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2016059056 | 2016-04-22 | ||
| PCT/EP2017/059293 WO2017182524A1 (fr) | 2016-04-22 | 2017-04-19 | Procédés de production d'arn simple brin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA44732A true MA44732A (fr) | 2021-06-02 |
| MA44732B1 MA44732B1 (fr) | 2021-11-30 |
Family
ID=58699087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA44732A MA44732B1 (fr) | 2016-04-22 | 2017-04-19 | Procédés de production d'arn simple brin |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20190153425A1 (fr) |
| EP (2) | EP3445850B1 (fr) |
| JP (2) | JP7000343B2 (fr) |
| KR (2) | KR102378404B1 (fr) |
| CN (1) | CN109072232B (fr) |
| AU (1) | AU2017251983B2 (fr) |
| BR (1) | BR112018069417A2 (fr) |
| CA (1) | CA3020481A1 (fr) |
| CY (1) | CY1124845T1 (fr) |
| DK (1) | DK3445850T3 (fr) |
| ES (1) | ES2900272T3 (fr) |
| HR (1) | HRP20211745T1 (fr) |
| HU (1) | HUE059314T2 (fr) |
| IL (1) | IL262304A (fr) |
| LT (1) | LT3445850T (fr) |
| MA (1) | MA44732B1 (fr) |
| MD (1) | MD3445850T2 (fr) |
| MX (1) | MX2018012880A (fr) |
| NZ (1) | NZ745940A (fr) |
| PL (1) | PL3445850T3 (fr) |
| PT (1) | PT3445850T (fr) |
| RS (1) | RS62612B1 (fr) |
| RU (2) | RU2021134269A (fr) |
| SG (2) | SG11201807573VA (fr) |
| SI (1) | SI3445850T1 (fr) |
| SM (1) | SMT202100681T1 (fr) |
| WO (1) | WO2017182524A1 (fr) |
| ZA (2) | ZA201805949B (fr) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102378404B1 (ko) | 2016-04-22 | 2022-03-24 | 비온테크 에스이 | 단일가닥 rna 제공 방법 |
| WO2018188730A1 (fr) | 2017-04-11 | 2018-10-18 | Biontech Rna Pharmaceuticals Gmbh | Arn pour le traitement de maladies auto-immunes |
| EP3668979A4 (fr) | 2017-08-18 | 2021-06-02 | Modernatx, Inc. | Procédés pour analyse par clhp |
| CN113874502A (zh) | 2019-03-11 | 2021-12-31 | 摩登纳特斯有限公司 | 补料分批体外转录方法 |
| AU2020233995A1 (en) * | 2019-03-12 | 2021-09-23 | BioNTech SE | Therapeutic RNA for prostate cancer |
| KR20220010500A (ko) * | 2019-05-20 | 2022-01-25 | 비온테크 에스이 | 난소암 치료용 rna |
| CN214973877U (zh) * | 2019-08-09 | 2021-12-03 | 胡桃钳医疗公司 | 用于形成治疗性多核苷酸的微流体设备及微流体路径装置 |
| WO2021050989A1 (fr) | 2019-09-13 | 2021-03-18 | Duke University | Anticorps zika et leur utilisation |
| WO2021081437A2 (fr) | 2019-10-23 | 2021-04-29 | Duke University | Compositions comprenant des enveloppes de vih opt v2 |
| BR112022014513A2 (pt) * | 2020-02-07 | 2022-09-20 | Ultragenyx Pharmaceutical Inc | Agentes caotrópicos para reduzir a formação de rna de fita dupla |
| WO2021160346A1 (fr) | 2020-02-13 | 2021-08-19 | Institut Pasteur | Vaccin à base d'acide nucléique contre le coronavirus sars-cov-2 |
| IL296781A (en) | 2020-03-30 | 2022-11-01 | BioNTech SE | Rna compositions targeting claudin-18.2 |
| EP3896160B1 (fr) * | 2020-04-17 | 2025-06-04 | Sartorius BIA Separations d.o.o. | Procédé de purification d'arn simple brin |
| EP3896161A1 (fr) * | 2020-04-17 | 2021-10-20 | Bia Separations D.O.O. | Procédé de purification d'arn simple brin |
| EP3896159B1 (fr) * | 2020-04-17 | 2025-05-28 | Sartorius BIA Separations d.o.o. | Procédé de purification d'arn simple brin utilisant un échangeur d'anions |
| CN115715324A (zh) * | 2020-06-19 | 2023-02-24 | 伊泽阿恩埃免疫疗法股份有限公司 | Rna纯化方法 |
| WO2025056938A1 (fr) | 2023-09-11 | 2025-03-20 | BioNTech SE | Compositions d'arn pour l'administration d'agents d'incrétine |
| EP4229208A4 (fr) | 2020-10-14 | 2024-10-30 | George Mason Research Foundation, Inc. | Méthodes de fabrication de nanoparticules lipidiques et compositions dérivées de celles-ci |
| WO2022218503A1 (fr) | 2021-04-12 | 2022-10-20 | BioNTech SE | Compositions de npl comprenant de l'arn et procédés de préparation, de stockage et d'utilisation de celles-ci |
| CA3198309A1 (fr) | 2020-11-16 | 2022-05-19 | Heinrich Haas | Compositions pharmaceutiques comprenant des particules et de l'arnm et leurs procedes de preparation et de stockage |
| AU2021379090A1 (en) | 2020-11-16 | 2023-06-15 | BioNTech SE | Lnp compositions comprising rna and methods for preparing, storing and using the same |
| EP4087938A2 (fr) | 2021-01-27 | 2022-11-16 | CureVac AG | Procédé de réduction des propriétés immunostimulatrices d'arn transcrit in vitro |
| CN115197935B (zh) * | 2021-04-08 | 2025-10-21 | 上海细胞治疗集团股份有限公司 | 纤维素色谱纯化rna的方法 |
| EP4322925A2 (fr) | 2021-04-12 | 2024-02-21 | BioNTech SE | Compositions d'arn comprenant une substance tampon et procédés de préparation, de stockage et d'utilisation de celles-ci |
| JP2024518335A (ja) | 2021-04-26 | 2024-05-01 | アンスティチュ パスツール | ＳＡＲＳ－ＣｏＶ－２に対するヒト中和モノクローナル抗体、及びそれらの使用 |
| KR20240021235A (ko) * | 2021-06-14 | 2024-02-16 | 2세븐티 바이오, 인코포레이티드 | 단일 가닥 rna 정제 방법 |
| US20240218353A1 (en) * | 2021-06-17 | 2024-07-04 | Modernatx, Inc. | Alternative rna purification strategies |
| CN113584014B (zh) * | 2021-07-27 | 2023-01-20 | 上海兆维科技发展有限公司 | 一种rna的制备方法、合成蛋白质的方法以及转录反应液 |
| TW202320842A (zh) | 2021-07-29 | 2023-06-01 | 德商拜恩技術股份公司 | 用於治療黑色素瘤之組合物及方法 |
| WO2023030635A1 (fr) | 2021-09-02 | 2023-03-09 | BioNTech SE | Test d'activité pour potentiel thérapeutique d'acide nucléique codant |
| JP2024535766A (ja) | 2021-09-10 | 2024-10-02 | バイオエヌテック エスエー | 治療に適した脂質ベースのｒｎａ製剤 |
| WO2023051926A1 (fr) | 2021-09-30 | 2023-04-06 | BioNTech SE | Traitement impliquant un arn non immunogène pour vaccination antigénique et antagonistes liant l'axe pd-1 |
| JP2024540948A (ja) | 2021-10-22 | 2024-11-06 | ビオンテック・ソシエタス・エウロパエア | 異なる投与のｒｎａを投与するための組成物 |
| US20250027108A1 (en) | 2021-10-29 | 2025-01-23 | CureVac SE | Improved circular rna for expressing therapeutic proteins |
| AU2022380858A1 (en) * | 2021-11-08 | 2024-05-30 | Seattle Project Corp. | Self-amplifying rna compositions and methods of use thereof |
| WO2023083434A1 (fr) | 2021-11-09 | 2023-05-19 | BioNTech SE | Arn codant pour la peptidoglycane hydrolase et son utilisation pour le traitement d'une infection bactérienne |
| US12529047B1 (en) | 2021-12-21 | 2026-01-20 | Modernatx, Inc. | mRNA quantification methods |
| WO2023126053A1 (fr) | 2021-12-28 | 2023-07-06 | BioNTech SE | Formulations à base de lipides pour administration d'arn |
| US20250345416A1 (en) | 2022-01-27 | 2025-11-13 | BioNTech SE | Pharmaceutical compositions for delivery of herpes simplex virus antigens and related methods |
| CN118785975A (zh) * | 2022-02-28 | 2024-10-15 | 瑞孚迪健康科学有限公司 | 用于分离和检测双链和单链核糖核酸(rna)的方法 |
| WO2023165681A1 (fr) | 2022-03-01 | 2023-09-07 | BioNTech SE | Nanoparticules lipidiques (npl) d'arn comprenant un polymère de polyoxazoline et/ou de polyoxazine |
| KR20230142248A (ko) | 2022-04-01 | 2023-10-11 | 주식회사 엘지에너지솔루션 | 연성회로기판을 포함하는 파우치형 전지셀 |
| WO2023193892A1 (fr) | 2022-04-05 | 2023-10-12 | BioNTech SE | Compositions d'acide nucléique comprenant un polyphosphate inorganique et procédés de préparation, de stockage et d'utilisation de celles-ci |
| JP2025516674A (ja) | 2022-05-13 | 2025-05-30 | ビオンテック エスエー | Ｈｉｖを標的とするｒｎａ組成物 |
| CN114921457B (zh) * | 2022-05-16 | 2023-09-29 | 硅羿科技（上海）有限公司 | 一种提取dsRNA的方法 |
| IL316504A (en) | 2022-05-25 | 2024-12-01 | BioNTech SE | RNA compositions for the delivery of monkeypox antigens and related methods |
| WO2024017479A1 (fr) | 2022-07-21 | 2024-01-25 | BioNTech SE | Cellules multifonctionnelles exprimant de manière transitoire un récepteur immunitaire et une ou plusieurs cytokines, leur utilisation et leurs procédés de production |
| WO2024028325A1 (fr) | 2022-08-01 | 2024-02-08 | BioNTech SE | Compositions d'acide nucléique contenant des composés conjugués-oligo éthylène glycol (oeg) amphiphiles et procédés d'utilisation de tels composés et compositions |
| EP4565266A1 (fr) | 2022-08-03 | 2025-06-11 | Nanoramic, Inc. | Arn pour la prévention ou le traitement de la tuberculose |
| WO2024027910A1 (fr) | 2022-08-03 | 2024-02-08 | BioNTech SE | Arn pour la prévention ou le traitement de la tuberculose |
| WO2024063789A1 (fr) | 2022-09-23 | 2024-03-28 | BioNTech SE | Compositions pour l'administration d'antigènes du paludisme et méthodes associées |
| AU2023347390A1 (en) | 2022-09-23 | 2025-04-10 | BioNTech SE | Compositions for delivery of plasmodium csp antigens and related methods |
| AU2023347387A1 (en) | 2022-09-23 | 2025-04-10 | BioNTech SE | Compositions for delivery of liver stage antigens and related methods |
| WO2024063788A1 (fr) | 2022-09-23 | 2024-03-28 | BioNTech SE | Compositions pour l'administration d'antigènes du paludisme et méthodes associées |
| WO2024074211A1 (fr) | 2022-10-06 | 2024-04-11 | BioNTech SE | Compositions d'arn ciblant la claudine-18.2 |
| IL319682A (en) | 2022-10-06 | 2025-05-01 | BioNTech SE | RNA complexes targeting claudin-18.2 |
| WO2024141955A1 (fr) | 2022-12-28 | 2024-07-04 | BioNTech SE | Compositions d'arn ciblant le vih |
| WO2024153324A1 (fr) | 2023-01-18 | 2024-07-25 | BioNTech SE | Formulations d'arn à usage pharmaceutique |
| JP2026508330A (ja) | 2023-02-28 | 2026-03-10 | バイオンテック・エスイー | 多重コーディング核酸のリンカー配列効力アッセイ |
| WO2024180363A1 (fr) | 2023-02-28 | 2024-09-06 | BioNTech SE | Dosages de puissance de séquence de lieur pour de multiples acides nucléiques codants |
| AU2024234022A1 (en) | 2023-03-09 | 2025-08-28 | BioNTech SE | Peptidoglycan hydrolases with bactericidal activity |
| EP4442276A1 (fr) | 2023-04-07 | 2024-10-09 | Institut Pasteur | Anticorps combinés contre les sarcovirus et leurs utilisations |
| WO2024216214A1 (fr) | 2023-04-14 | 2024-10-17 | BioNTech SE | Arn pour la prévention ou le traitement de la tuberculose |
| WO2024213776A1 (fr) | 2023-04-14 | 2024-10-17 | BioNTech SE | Arn pour prévenir ou traiter la tuberculose |
| EP4694919A1 (fr) | 2023-04-14 | 2026-02-18 | BioNTech SE | Arn pour la prévention ou le traitement de la tuberculose |
| WO2024228044A1 (fr) | 2023-05-03 | 2024-11-07 | BioNTech SE | Variants de csp optimisés et méthodes associées |
| AU2024265158A1 (en) | 2023-05-03 | 2025-11-06 | BioNTech SE | Optimized csp variants and related methods |
| WO2024230783A1 (fr) * | 2023-05-11 | 2024-11-14 | 中国科学院过程工程研究所 | Procédé à haut rendement et kit de préparation d'arnm par réduction ou inhibition de la formation d'arn double brin pendant une transcription in vitro |
| WO2024236192A1 (fr) | 2023-05-17 | 2024-11-21 | Institut Pasteur | Hétérodimère de protéines a16 et g9 de poxvirus en tant qu'agent immunogène |
| WO2025003406A1 (fr) | 2023-06-29 | 2025-01-02 | BioNTech SE | Système multiplateforme modulaire pour la production de médicament à arnm |
| WO2025024324A1 (fr) | 2023-07-21 | 2025-01-30 | BioNTech SE | Compositions d'administration d'antigènes de plasmodium et méthodes associées |
| WO2025024335A2 (fr) | 2023-07-21 | 2025-01-30 | BioNTech SE | Compositions pour l'administration d'antigènes de plasmodium et méthodes associées |
| AU2024299365A1 (en) | 2023-07-24 | 2026-01-08 | BioNTech SE | Compositions for delivery of plasmodium antigens and related methods |
| WO2025026866A1 (fr) | 2023-07-28 | 2025-02-06 | BioNTech SE | Agents thérapeutiques à base d'arn à toxicité réduite |
| AU2024316307A1 (en) | 2023-08-03 | 2026-02-26 | BioNTech SE | Pharmaceutical compositions for delivery of herpes simplex virus antigens and related methods |
| WO2025027576A2 (fr) | 2023-08-03 | 2025-02-06 | BioNTech SE | Compositions d'arn ciblant le vih |
| WO2025027579A2 (fr) | 2023-08-03 | 2025-02-06 | BioNTech SE | Compositions d'arn ciblant le vih |
| WO2025030154A1 (fr) | 2023-08-03 | 2025-02-06 | The Trustees Of The University Of Pennsylvania | Compositions pharmaceutiques pour l'administration d'antigènes de glycoprotéine b du virus herpès simplex et méthodes associées |
| WO2025054556A1 (fr) | 2023-09-07 | 2025-03-13 | BioNTech SE | Compositions d'arn pour l'administration d'antigènes de mpox et méthodes associées |
| WO2025051381A1 (fr) | 2023-09-08 | 2025-03-13 | BioNTech SE | Procédés et compositions pour l'expression localisée d'arn administré |
| WO2025057088A1 (fr) | 2023-09-11 | 2025-03-20 | BioNTech SE | Compositions d'arn pour administration d'agents d'incrétine |
| EP4527937A1 (fr) | 2023-09-20 | 2025-03-26 | BioNTech SE | Transcription in vitro en un seul pot de plusieurs molécules d'adn en plusieurs molécules d'arn |
| WO2025064850A1 (fr) | 2023-09-22 | 2025-03-27 | BioNTech SE | Constructions d'arn avec des dégrons n-terminaux pour améliorer une réponse immunitaire |
| EP4689074A1 (fr) | 2023-10-13 | 2026-02-11 | SmartCella Solutions AB | Procédés et compositions pour l'administration de constructions d'arnm non modifiées à l'aide de cellules souches mésenchymateuses |
| WO2025106738A1 (fr) | 2023-11-15 | 2025-05-22 | BioNTech SE | Compositions immunogènes de sars-cov-2 |
| WO2025133908A1 (fr) * | 2023-12-20 | 2025-06-26 | Solventum Intellectual Properties Company | Procédé de séparation d'acides nucléiques |
| WO2025153707A1 (fr) | 2024-01-19 | 2025-07-24 | Spikimm | Anticorps monoclonaux neutralisants à large spectre dirigés contre le sars-cov-2 et leurs utilisations |
| WO2025202937A1 (fr) | 2024-03-26 | 2025-10-02 | BioNTech SE | Vaccins anticancéreux |
| WO2025213131A1 (fr) | 2024-04-05 | 2025-10-09 | BioNTech SE | Compositions d'arn pour l'administration d'antigènes d'orthopox et procédés associés |
| WO2025223684A1 (fr) | 2024-04-23 | 2025-10-30 | BioNTech SE | Méthodes et compositions pour stimuler une réponse immunitaire |
| WO2025264662A1 (fr) | 2024-06-18 | 2025-12-26 | BioNTech SE | Compositions et méthodes de traitement d'un mélanome |
| WO2026015882A1 (fr) | 2024-07-12 | 2026-01-15 | BioNTech SE | Fragments d'antigène hsv et procédés associés |
| WO2026041793A1 (fr) | 2024-08-23 | 2026-02-26 | BioNTech SE | Protéines chimériques comprenant des domaines protéiques non humains pour améliorer l'antigénicité |
| WO2026047153A1 (fr) | 2024-08-28 | 2026-03-05 | BioNTech SE | Test d'activité biologique pour de multiples acides nucléiques codants |
| WO2026047603A1 (fr) | 2024-08-28 | 2026-03-05 | BioNTech SE | Compositions immunogènes contre sars-cov-2 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2936240A1 (de) * | 1979-09-07 | 1981-03-26 | Bayer Ag, 51373 Leverkusen | Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens |
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US5374548A (en) | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| MX9203291A (es) | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| NL8900725A (nl) * | 1989-03-23 | 1990-10-16 | Az Univ Amsterdam | Werkwijze en combinatie van middelen voor het isoleren van nucleinezuur. |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| PT1309726E (pt) | 2000-03-30 | 2010-03-08 | Whitehead Biomedical Inst | Mediadores de interferência por rna específicos de sequência de rna |
| JP3692395B2 (ja) * | 2000-09-01 | 2005-09-07 | 独立行政法人農業・生物系特定産業技術研究機構 | ベクターモノカリオンを用いた紫紋羽病菌に対するゲノムが２本鎖ｒｎａである糸状菌に寄生するウイルスを導入する新規方法 |
| US20050059024A1 (en) * | 2003-07-25 | 2005-03-17 | Ambion, Inc. | Methods and compositions for isolating small RNA molecules |
| EP2311994A1 (fr) * | 2003-08-01 | 2011-04-20 | Life Technologies Corporation | Compositions et procédés de préparation de courtes molécules d'ARN et d'autres acides nucléiques |
| US9012219B2 (en) * | 2005-08-23 | 2015-04-21 | The Trustees Of The University Of Pennsylvania | RNA preparations comprising purified modified RNA for reprogramming cells |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| WO2007103485A2 (fr) * | 2006-03-08 | 2007-09-13 | Promega Corporation | Purification de petits arn |
| CN101086011B (zh) * | 2006-06-08 | 2010-12-08 | 河南农业大学 | 食用菌和植物双链rna病毒检测试剂盒及其应用 |
| DE102006061015A1 (de) | 2006-12-22 | 2008-06-26 | Curevac Gmbh | Verfahren zur Reinigung von RNA im präparativen Maßstab mittels HPLC |
| DK2167523T3 (da) | 2007-06-19 | 2014-09-08 | Univ Louisiana State | Syntese og anvendelse af anti-reverse phosphorothioatanaloger af messenger-rna-cappen |
| SI3112467T1 (en) | 2009-12-07 | 2018-06-29 | The Trustees Of The University Of Pennsylvania | Rna preparations comprising purified modified rna for reprogramming cells |
| EP3421601B1 (fr) | 2011-12-30 | 2019-12-04 | Cellscript, Llc | Fabrication et utilisation d'un arnss synthétisé in vitro à introduire dans des cellules de mammifères pour induire un effet biologique ou biochimique |
| WO2016193206A1 (fr) * | 2015-05-29 | 2016-12-08 | Curevac Ag | Procédé de production et de purification d'arn, comprenant au moins une étape de filtration à flux tangentiel |
| KR102378404B1 (ko) | 2016-04-22 | 2022-03-24 | 비온테크 에스이 | 단일가닥 rna 제공 방법 |
-
2017
- 2017-04-19 KR KR1020187030368A patent/KR102378404B1/ko active Active
- 2017-04-19 US US16/091,389 patent/US20190153425A1/en not_active Abandoned
- 2017-04-19 CA CA3020481A patent/CA3020481A1/fr active Pending
- 2017-04-19 AU AU2017251983A patent/AU2017251983B2/en active Active
- 2017-04-19 JP JP2018555164A patent/JP7000343B2/ja active Active
- 2017-04-19 SG SG11201807573VA patent/SG11201807573VA/en unknown
- 2017-04-19 MD MDE20190258T patent/MD3445850T2/ro unknown
- 2017-04-19 ES ES17722695T patent/ES2900272T3/es active Active
- 2017-04-19 EP EP17722695.8A patent/EP3445850B1/fr active Active
- 2017-04-19 LT LTEPPCT/EP2017/059293T patent/LT3445850T/lt unknown
- 2017-04-19 WO PCT/EP2017/059293 patent/WO2017182524A1/fr not_active Ceased
- 2017-04-19 NZ NZ745940A patent/NZ745940A/en unknown
- 2017-04-19 KR KR1020227009308A patent/KR102565881B1/ko active Active
- 2017-04-19 RU RU2021134269A patent/RU2021134269A/ru unknown
- 2017-04-19 SG SG10202010471UA patent/SG10202010471UA/en unknown
- 2017-04-19 BR BR112018069417-7A patent/BR112018069417A2/pt not_active IP Right Cessation
- 2017-04-19 CN CN201780024328.9A patent/CN109072232B/zh active Active
- 2017-04-19 PT PT177226958T patent/PT3445850T/pt unknown
- 2017-04-19 PL PL17722695T patent/PL3445850T3/pl unknown
- 2017-04-19 HR HRP20211745TT patent/HRP20211745T1/hr unknown
- 2017-04-19 SI SI201730980T patent/SI3445850T1/sl unknown
- 2017-04-19 RU RU2018136601A patent/RU2760790C2/ru active
- 2017-04-19 RS RS20211459A patent/RS62612B1/sr unknown
- 2017-04-19 DK DK17722695.8T patent/DK3445850T3/da active
- 2017-04-19 MX MX2018012880A patent/MX2018012880A/es unknown
- 2017-04-19 MA MA44732A patent/MA44732B1/fr unknown
- 2017-04-19 HU HUE17722695A patent/HUE059314T2/hu unknown
- 2017-04-19 SM SM20210681T patent/SMT202100681T1/it unknown
- 2017-04-19 EP EP21204500.9A patent/EP4008782B1/fr active Active
-
2018
- 2018-09-05 ZA ZA2018/05949A patent/ZA201805949B/en unknown
- 2018-10-11 IL IL262304A patent/IL262304A/en unknown
-
2019
- 2019-08-22 ZA ZA2019/05536A patent/ZA201905536B/en unknown
-
2021
- 2021-11-26 CY CY20211101032T patent/CY1124845T1/el unknown
- 2021-12-23 JP JP2021209047A patent/JP7335313B2/ja active Active
-
2025
- 2025-08-22 US US19/307,372 patent/US20260071201A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA44732A (fr) | Procédés de production d'arn simple brin | |
| GB2576227B (en) | Animation production system | |
| MA47606A (fr) | Procédés de purification d'arn messager | |
| MA47605A (fr) | Procédés de purification d'arn messager | |
| EP2971033A4 (fr) | Procédés de fabrication pour la production de transcrits d'arn | |
| EP3765021A4 (fr) | Nouveaux procédés | |
| EP3778914A4 (fr) | Procédé de production d'arn simple brin | |
| GB2558335B (en) | Novel processes for the production of oligonucleotides | |
| EP3302794A4 (fr) | Procédé d'époxydation | |
| EP3302441A4 (fr) | Procédés de production du brivaracetam | |
| EP3378869A4 (fr) | Procédé de production d'oligonucléotide | |
| EP3247796A4 (fr) | Nanostructructures d'acides nucléiques pourvues de motifs de noyau | |
| EP3711892A4 (fr) | Procédé d'assemblage | |
| EP3398957A4 (fr) | Procédé de synthèse de l'ételcalcétide | |
| MA48798A (fr) | Procédé de production d'ozanimod | |
| MA41842A (fr) | Nouveaux procédés de sélection d'épitope | |
| EP3314026A4 (fr) | Polymorphisme mononucléotidique danshla-b*15:02 | |
| EP3684757A4 (fr) | Procédé de production d'alkylaromatiques | |
| EP3345152A4 (fr) | Portail d'enchères continues | |
| EP3640216A4 (fr) | Procédé d'adsorption | |
| MA47014A (fr) | Procédé de purification d'antibiotiques lipopeptidiques | |
| FR3045538B1 (fr) | Moto-reducteur d'essuie-glace | |
| EP3265469A4 (fr) | Nouveaux procédés de synthèse | |
| SI3272560T1 (sl) | Veriga za pnevmatiko s 45-stopinjskim verižnim nizom | |
| GB201609403D0 (en) | Booklet production |