MA47609A - Anticorps anti-il31 à usage vétérinaire - Google Patents
Anticorps anti-il31 à usage vétérinaireInfo
- Publication number
- MA47609A MA47609A MA047609A MA47609A MA47609A MA 47609 A MA47609 A MA 47609A MA 047609 A MA047609 A MA 047609A MA 47609 A MA47609 A MA 47609A MA 47609 A MA47609 A MA 47609A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- veterinary use
- veterinary
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463543P | 2017-02-24 | 2017-02-24 | |
| PCT/US2017/023788 WO2018156180A1 (fr) | 2017-02-24 | 2017-03-23 | Anticorps anti-il31 à usage vétérinaire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA47609A true MA47609A (fr) | 2020-01-01 |
Family
ID=63245488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA047609A MA47609A (fr) | 2017-02-24 | 2018-02-09 | Anticorps anti-il31 à usage vétérinaire |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US10093731B2 (fr) |
| EP (1) | EP3585429A4 (fr) |
| JP (3) | JP7277370B2 (fr) |
| KR (1) | KR20190127703A (fr) |
| CN (2) | CN117603350A (fr) |
| AU (2) | AU2018224711B2 (fr) |
| BR (1) | BR112019017308A2 (fr) |
| CA (1) | CA3053525A1 (fr) |
| MA (1) | MA47609A (fr) |
| MX (1) | MX2024012304A (fr) |
| WO (1) | WO2018156180A1 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA037960B1 (ru) | 2016-04-27 | 2021-06-15 | Эббви Инк. | Способ лечения эозинофильного эзофагита с применением антитела против il-13 |
| US10093731B2 (en) | 2017-02-24 | 2018-10-09 | Kindred Biosciences, Inc. | Anti-IL31 antibodies for veterinary use |
| US11207390B2 (en) * | 2017-03-07 | 2021-12-28 | Universität Zürich | Treatment of pruritus in horses |
| CA3093709C (fr) | 2018-03-16 | 2024-03-26 | Zoetis Services Llc | Vaccins peptidiques contre l'interleukine-31 |
| KR20220002859A (ko) * | 2018-12-19 | 2022-01-07 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | T 세포 림프종 및 백혈병에 대한 cd2/5/7 녹-아웃 항-cd2/5/7 키메라 항원 수용체 t 세포의 용도 |
| EP4021499A4 (fr) * | 2019-08-29 | 2024-08-07 | Elanco US Inc. | Anticorps anti-il31 à usage vétérinaire |
| CN114829396A (zh) * | 2019-12-20 | 2022-07-29 | 英特维特国际股份有限公司 | 用于治疗特应性皮炎的双特异性犬源化抗体和双特异性结合伴体 |
| WO2021123089A1 (fr) | 2019-12-20 | 2021-06-24 | Intervet International B.V. | Anticorps dirigés contre le récepteur alpha de l'interleukine-4 canine |
| CN115697403A (zh) * | 2020-03-10 | 2023-02-03 | 迪赞纳生命科学公开有限公司 | Il-6/il-6r抗体的组合物及其使用方法 |
| PH12022552742A1 (en) * | 2020-04-17 | 2024-03-25 | Zoetis Services Llc | Canine antibody variants |
| EP4136109A1 (fr) * | 2020-04-17 | 2023-02-22 | Zoetis Services LLC | Variants d'anticorps félin |
| CA3173864A1 (fr) * | 2020-04-22 | 2021-10-28 | Shyr Jiann Li | Anticorps anti-il31 a action prolongee a usage veterinaire |
| WO2022010652A1 (fr) | 2020-07-10 | 2022-01-13 | Invetx Inc. | Compositions permettant d'augmenter la demi-vie d'un agent thérapeutique chez les félins et procédés d'utilisation |
| US12577310B2 (en) | 2020-10-15 | 2026-03-17 | Intervet Inc. | Caninized antibodies to canine interleukin-31 receptor alpha |
| EP4247848A4 (fr) * | 2020-11-23 | 2025-10-01 | Scout Bio Inc | Molécules de liaison à l'antigène et leurs utilisations |
| US20220273793A1 (en) * | 2021-02-22 | 2022-09-01 | Zoetis Services Llc | Horse il-31 induced pruritus model |
| EP4388006A1 (fr) | 2021-08-20 | 2024-06-26 | Intervet International B.V. | Protéines de fusion homodimères pour le traitement de la dermatite atopique |
| US20250340654A1 (en) | 2021-12-16 | 2025-11-06 | Intervet Inc. | Caninized antibodies to canine interleukin-31 receptor alpha ii |
| WO2024145280A2 (fr) | 2022-12-27 | 2024-07-04 | Invetx, Inc. | Polypeptides à liaison modifiée au récepteur fc néonatal (fcrn) et procédés d'utilisation |
| EP4642795A2 (fr) | 2022-12-27 | 2025-11-05 | Invetx, Inc. | Polypeptides à liaison modifiée au récepteur fc néonatal (fcrn) et procédés d'utilisation |
| KR20250151402A (ko) | 2023-01-20 | 2025-10-21 | 인베티엑스 인코포레이티드 | 반려 동물에서 사용하기 위한 이중특이적 결합제 |
| CN120897928A (zh) | 2023-02-13 | 2025-11-04 | 英特维特国际股份有限公司 | 针对犬il-4的犬抗体 |
| JP2026508149A (ja) | 2023-02-13 | 2026-03-10 | インターベット インターナショナル ベー. フェー. | イヌil-13に対するイヌ抗体 |
| CN120865402A (zh) * | 2023-11-27 | 2025-10-31 | 宁波贝安生物科技有限公司 | 抗il-31的抗体及其用途 |
| CN118667001B (zh) * | 2024-07-16 | 2025-05-06 | 华中农业大学 | 一种抗犬il-31的单克隆抗体及其应用 |
| CN120209126B (zh) * | 2025-05-28 | 2025-09-16 | 中国医学科学院医学生物学研究所 | 人偏肺病毒单克隆抗体及其应用 |
Family Cites Families (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2134212T3 (es) | 1991-04-25 | 1999-10-01 | Chugai Pharmaceutical Co Ltd | Anticuerpo humano reconstituido contra el receptor de la interleuquina 6 humano. |
| JP3919830B2 (ja) | 1992-11-28 | 2007-05-30 | 財団法人化学及血清療法研究所 | 抗ネコヘルペスウイルス−1組換え抗体および該抗体をコードする遺伝子断片 |
| CA2163976C (fr) | 1993-05-28 | 2010-06-29 | Didier J. Leturcq | Methodes et compositions pour inhiber l'activation de cellules via cd14 |
| EP2305027B1 (fr) | 1996-12-03 | 2014-07-02 | Amgen Fremont Inc. | Mammifères trangèniques obtenus par génie génétique contenant des loci des immunoglobulines humaines qui comprennent plusieurs régions de VH et de Vkappa, et anticorps aussi obtenus. |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| CA2401491C (fr) | 2000-03-03 | 2011-07-05 | Kyowa Kirin Co., Ltd. | Anticorps fixateur ccr4 et ses utilisations diagnostiques et therapeutiques |
| IL161677A0 (en) | 2001-11-08 | 2004-09-27 | Protein Design Labs | Stable liquid pharmaceutical formulation of igg antibodies |
| EP1485126A4 (fr) | 2001-12-21 | 2007-03-21 | Idexx Lab Inc | Domaines variable d'immunoglobuline canine, anticorps caninises, et procede de production et d'utilisation associes |
| ATE401390T1 (de) | 2002-01-18 | 2008-08-15 | Zymogenetics Inc | Zytokin (zcytor17-ligand) |
| MXPA05003884A (es) | 2002-10-16 | 2005-10-05 | Euro Celtique Sa | Anticuerpos que enlazan polipeptidos ca 125/0772p a celulas asociadas y metodos de uso de los mismos. |
| AR049390A1 (es) | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| EP1671642A1 (fr) | 2004-12-15 | 2006-06-21 | Universite D'angers | Composés contenant des (ant)agonistes de l'oncostatin M (OSM), IL-31 et IFN-gamma pour moduler la migration et fonction de keratinocytes au moyen d'un recepteur comprenant l'OSMRbeta comme sousunité, et applications correspondantes |
| AU2006207945B2 (en) | 2005-01-28 | 2012-02-09 | Zymogenetics, Inc. | Homogeneous preparations of IL-31 |
| CA2594490A1 (fr) | 2005-02-14 | 2006-08-24 | Zymogenetics Inc. | Methodes de traitement d'affections de la peau en employant un antagoniste de il-31ra |
| EP1856150A2 (fr) | 2005-02-14 | 2007-11-21 | ZymoGenetics, Inc. | Methodes de traitement des maladies mediees par des cellules positives a l'egard de l'antigene lymphocytaire cutane |
| JP2008532559A (ja) | 2005-03-19 | 2008-08-21 | メディカル リサーチ カウンシル | ウイルス感染の治療及び予防又は治療及び予防の改善 |
| US20100104564A1 (en) | 2005-03-29 | 2010-04-29 | Genevieve Hansen | Altered Antibody Fc Regions and Uses Thereof |
| KR101446989B1 (ko) | 2005-05-06 | 2014-10-15 | 지모제넥틱스, 인코포레이티드 | Il-31 단클론성 항체 및 사용법 |
| RU2444528C2 (ru) | 2005-05-06 | 2012-03-10 | Займоджинетикс, Инк. | Моноклональные антитела против il-31 и способы применения |
| US8101183B2 (en) | 2005-05-06 | 2012-01-24 | Zymogentics, Inc. | Variable region sequences of IL-31 monoclonal antibodies |
| US20130216542A1 (en) | 2005-05-06 | 2013-08-22 | Zymogenetics, Inc. | Variable region sequences of il-31 monoclonal antibodies and methods of use |
| CN1896229A (zh) | 2005-06-29 | 2007-01-17 | 北京天广实生物技术有限公司 | 一种新型抗cd20嵌合抗体的制备及其用途 |
| JP5289963B2 (ja) | 2005-10-21 | 2013-09-11 | メルク・シャープ・アンド・ドーム・コーポレーション | 抗addlモノクローナル抗体およびその使用 |
| CA2636288C (fr) | 2006-01-10 | 2015-02-24 | Zymogenetics, Inc. | Procedes de traitement de la douleur et de l'inflammation dans les tissus neuronaux au moyen d'antagonistes de l'il-31 |
| NZ574215A (en) | 2006-07-18 | 2012-07-27 | Sanofi Aventis | Antagonist antibody against epha2 for the treatment of cancer |
| RU2009111884A (ru) | 2006-09-01 | 2010-10-10 | Займоджинетикс, Инк. (Us) | Последовательности вариабельных областей моноклональных антител против il-31 и способы использования |
| KR101544108B1 (ko) | 2006-09-08 | 2015-08-13 | 애브비 바하마스 리미티드 | 인터루킨-13 결합 단백질 |
| AU2007319604B2 (en) | 2006-10-19 | 2011-03-24 | Csl Limited | High affinity antibody antagonists of interleukin-13 receptor alpha 1 |
| EP2061496A2 (fr) | 2007-01-10 | 2009-05-27 | Zymogenetics, Inc. | Méthodes d'utilisation de il-31 pour le traitement de l'hyper-réactivité des voies respiratoires et de l'asthme |
| JOP20080381B1 (ar) | 2007-08-23 | 2023-03-28 | Amgen Inc | بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9) |
| LT2796466T (lt) | 2007-12-07 | 2018-02-26 | Zymogenetics, Inc. | Humanizuotų antikūnų molekulės, specifinės il-31 atžvilgiu |
| TWI700293B (zh) | 2008-04-11 | 2020-08-01 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗體 |
| EP2384326B1 (fr) | 2008-08-20 | 2014-04-23 | Zoetis LLC | Composés pyrrolo[2,3-d]pyrimidines |
| US8337842B2 (en) | 2008-09-04 | 2012-12-25 | Vet Therapeutics, Inc. | Monoclonal antibodies |
| CN102131524B (zh) | 2008-11-07 | 2014-05-14 | 星系生物科技责任有限公司 | 成纤维细胞生长因子受体2的单克隆抗体 |
| US20110287454A1 (en) | 2008-11-25 | 2011-11-24 | Cornell University | Methods for monoclonal antibody production |
| WO2011065935A1 (fr) | 2009-11-24 | 2011-06-03 | Cornell University | Procédés de production d'anticorps monoclonaux |
| AU2013203075A1 (en) | 2008-11-28 | 2013-05-02 | Abbott Laboratories | Stable antibody compositions and methods for stabilizing same |
| US20110165063A1 (en) | 2009-01-29 | 2011-07-07 | Abbott Laboratories | Il-1 binding proteins |
| WO2010117448A2 (fr) | 2009-04-05 | 2010-10-14 | Provenance Biopharmaceuticals Corp. | Immunocytokines chimériques et leurs procédés d'utilisation |
| CN102459339A (zh) | 2009-06-22 | 2012-05-16 | 派特塞尔有限公司 | 药物制剂 |
| TW201119676A (en) | 2009-10-15 | 2011-06-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| TWI672318B (zh) | 2010-02-24 | 2019-09-21 | 美商免疫遺傳股份有限公司 | 葉酸受體1抗體類和免疫共軛物類及彼等之用途 |
| MY161302A (en) | 2010-05-14 | 2017-04-14 | Abbvie Inc | IL-1 binding proteins |
| TWI560199B (en) | 2010-08-31 | 2016-12-01 | Sanofi Sa | Peptide or peptide complex binding to α2 integrin and methods and uses involving the same |
| US9255925B2 (en) | 2010-10-20 | 2016-02-09 | Medical Diagnostic Laboratories, Llc | ELISA detection of urine DEK to predict and diagnose bladder cancer in humans |
| JP6013915B2 (ja) | 2010-11-17 | 2016-10-25 | 中外製薬株式会社 | 血液凝固第viii因子の機能を代替する機能を有する多重特異性抗原結合分子 |
| AR084210A1 (es) | 2010-12-08 | 2013-05-02 | Abbott Lab | PROTEINAS DE UNION AL TNF-a |
| TW201307388A (zh) | 2010-12-21 | 2013-02-16 | Abbott Lab | Il-1結合蛋白 |
| ES2667568T3 (es) | 2011-04-25 | 2018-05-11 | Daiichi Sankyo Company, Limited | Anticuerpo anti-B7-H3 |
| AR086250A1 (es) | 2011-05-05 | 2013-11-27 | Hoffmann La Roche | Polipeptido de fusion presentador de una secuencia de aminoacidos y utilizacion del mismo |
| CN103732621B (zh) | 2011-05-06 | 2020-04-24 | 內克斯威特澳大利亚私人有限公司 | 抗神经生长因子抗体及其制备和使用方法 |
| EP2710040B1 (fr) | 2011-05-19 | 2017-07-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anticorps anti-her3 humain et leurs utilisations |
| US8790651B2 (en) | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
| KR20130036993A (ko) | 2011-10-05 | 2013-04-15 | 삼성전자주식회사 | c-Met의 SEMA 도메인 내의 에피토프에 특이적으로 결합하는 항체 |
| JO3532B1 (ar) * | 2013-03-13 | 2020-07-05 | Regeneron Pharma | الأجسام المضادة لمضاد انترلوكين-33 واستعمالاتها |
| CN113788897A (zh) | 2013-03-15 | 2021-12-14 | 拜尔健康护理有限责任公司 | 改善药代动力学的具有跨pH范围差异结合的抗TFPI抗体变体 |
| KR20150127591A (ko) | 2013-03-15 | 2015-11-17 | 리제너론 파아마슈티컬스, 인크. | Il-33 길항제 및 이의 용도 |
| KR20240122922A (ko) | 2013-03-27 | 2024-08-13 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| US20160102127A1 (en) | 2013-05-27 | 2016-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Targeted modulation of macrophages |
| CN110511279B (zh) * | 2013-05-30 | 2024-03-29 | 基尼克萨制药有限公司 | 制瘤素m受体抗原结合蛋白 |
| TW201537175A (zh) | 2013-06-28 | 2015-10-01 | Chugai Pharmaceutical Co Ltd | 預測罹患具皮膚搔癢之疾病的患者對il-31拮抗劑之治療的反應之方法 |
| US20150004161A1 (en) | 2013-07-01 | 2015-01-01 | University Of Maryland | Fc Coupled Compositions and Methods of Their Use |
| WO2015042596A1 (fr) * | 2013-09-23 | 2015-03-26 | Kindred Biosciences, Inc | Traitement de la dermite atopique chez des animaux non humains |
| WO2015067755A2 (fr) | 2013-11-07 | 2015-05-14 | Novo Nordisk A/S | Nouvelles méthodes et nouveaux anticorps destinés au traitement d'une coagulopathie |
| WO2015086830A1 (fr) | 2013-12-13 | 2015-06-18 | Delenex Therapeutics Ag | Polypeptides pénétrant dans la peau |
| CN103965357B (zh) | 2013-12-31 | 2016-08-17 | 嘉和生物药业有限公司 | 一种抗人rankl抗体 |
| TWI694836B (zh) * | 2014-05-16 | 2020-06-01 | 英商葛蘭素史克智慧財產管理有限公司 | 抗體調配物 |
| AU2015292406B2 (en) | 2014-07-25 | 2021-03-11 | Cytomx Therapeutics, Inc | Anti-CD3 antibodies, activatable anti-CD3 antibodies, multispecific anti-CD3 antibodies, multispecific activatable anti-CD3 antibodies, and methods of using the same |
| CN104403004B (zh) | 2014-11-24 | 2017-10-13 | 苏州丁孚靶点生物技术有限公司 | 抗体‑干扰素异二聚体的制备和用途 |
| EP3250589A4 (fr) | 2015-01-29 | 2018-06-20 | Nexvet Australia Pty Ltd | Agents diagnostiques et thérapeutiques |
| CN104710528B (zh) * | 2015-03-13 | 2019-02-15 | 西北农林科技大学 | 一种特异性结合PRRS病毒非结构蛋白Nsp9纳米抗体及其应用 |
| MA43918A (fr) | 2015-04-14 | 2018-12-05 | Chugai Pharmaceutical Co Ltd | Composition pharmaceutique pour la prã‰vention et/ou le traitement de la dermatite atopique contenant comme principe actif un antagoniste de l'il-31 |
| WO2016170176A1 (fr) * | 2015-04-22 | 2016-10-27 | Curevac Ag | Composition contenant de l'arn pour le traitement de maladies tumorales |
| WO2015151079A2 (fr) | 2015-06-20 | 2015-10-08 | Hangzhou Dac Biotech Co, Ltd | Analogues d'auristatine et leur conjugués avec des molécules de liaison cellulaire |
| WO2017025698A1 (fr) | 2015-08-11 | 2017-02-16 | Queen Mary University Of London | Anticorps bispécifiques, clivables |
| TW201729810A (zh) | 2015-10-26 | 2017-09-01 | 札爾科製藥公司 | 嘧啶組成物、其超純組成物及鹽類、製造彼之方法、及使用彼於治療組織胺h4受體(h 4 )仲介之疾病與病情之方法 |
| TWI780045B (zh) * | 2016-03-29 | 2022-10-11 | 台灣浩鼎生技股份有限公司 | 抗體、醫藥組合物及方法 |
| US11649283B2 (en) | 2016-04-15 | 2023-05-16 | Immunext, Inc. | Anti-human vista antibodies and use thereof |
| US10836796B2 (en) | 2016-04-20 | 2020-11-17 | Hangzhou Dac Biotech Co., Ltd. | Derivatives of amanita toxins and their conjugation to a cell binding molecule |
| EP3526246A1 (fr) | 2016-10-17 | 2019-08-21 | Vetoquinol SA | Région constante modifiée d'un anticorps |
| CN116143678A (zh) | 2016-11-14 | 2023-05-23 | 杭州多禧生物科技有限公司 | 偶联连接体,含有此连接体的细胞结合分子-药物偶联物及其制备和应用 |
| TWI857389B (zh) | 2016-12-01 | 2024-10-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| US10093731B2 (en) * | 2017-02-24 | 2018-10-09 | Kindred Biosciences, Inc. | Anti-IL31 antibodies for veterinary use |
| WO2018156367A1 (fr) | 2017-02-24 | 2018-08-30 | Kindred Biosciences, Inc. | Anticorps anti-il31 à usage vétérinaire |
| EP3606922A4 (fr) | 2017-04-06 | 2021-03-03 | Hangzhou Dac Biotech Co., Ltd | Conjugaison d'un médicament cytotoxique avec une bis-liaison |
| SG11201909160WA (en) | 2017-04-11 | 2019-10-30 | Inhibrx Inc | Multispecific polypeptide constructs having constrained cd3 binding and methods of using the same |
| BR112019021812A2 (pt) | 2017-04-21 | 2020-05-26 | Kindred Biosciences, Inc. | Molécula receptora de il4/il13 para uso veterinário |
| EP3483180A1 (fr) | 2017-11-14 | 2019-05-15 | Affilogic | Molécules multispécifiques |
| MX2020006105A (es) | 2017-12-11 | 2020-11-09 | Ubi Ip Holdings | Inmunógenos peptídicos de il-31 y formulaciones de estos para el tratamiento y/o la prevención de la dermatitis atópica. |
| MX2020006192A (es) | 2017-12-31 | 2020-08-20 | Hangzhou Dac Biotech Co Ltd | Un conjugado de un analogo de tubulisina con enlazadores ramificados. |
| AU2019234220B2 (en) | 2018-03-16 | 2025-09-11 | Zoetis Services Llc | Interleukin-31 monoclonal antibodies for veterinary use |
| WO2019183449A1 (fr) | 2018-03-23 | 2019-09-26 | North Carolina State University | Méthodes et compositions pour troubles allergiques |
| WO2019200022A1 (fr) | 2018-04-11 | 2019-10-17 | Inhibrx, Inc. | Produits de recombinaison de polypeptides plurispécifiques comprenant une fixation à cd3 contrainte et méthodes d'utilisation associées |
| MX2020014083A (es) | 2018-07-05 | 2021-04-12 | Hangzhou Dac Biotech Co Ltd | Un derivado de dímero de pirrolobenzodiazepina (pbd) reticulado y sus conjugados. |
| JP2022500037A (ja) | 2018-09-14 | 2022-01-04 | キンドレッド バイオサイエンシズ インコーポレイテッド | 獣医学的使用のための抗il4受容体抗体 |
| CN113195487A (zh) | 2018-10-12 | 2021-07-30 | 杭州多禧生物科技有限公司 | 2,3-二氨基琥珀酰基偶联物连接子 |
| BR112021006977A2 (pt) | 2018-10-18 | 2021-07-27 | Kindred Biosciences, Inc. | variantes fc com ligação alterada a receptor fc neonatal (fcrn) para uso veterinário |
| WO2020086886A1 (fr) | 2018-10-25 | 2020-04-30 | Kindred Biosciences, Inc. | Molécule du récepteur d'il4/il13 à usage vétérinaire |
| WO2020092015A1 (fr) | 2018-11-02 | 2020-05-07 | University Of Rochester | Atténuation thérapeutique d'une infection épithéliale |
| AU2019416344A1 (en) | 2018-12-27 | 2021-07-01 | Elanco Us Inc. | IgG Fc variants for veterinary use |
| AU2020205073A1 (en) | 2019-01-03 | 2021-08-19 | Invetx Inc. | Compositions for increasing half-life of a therapeutic agent in canines and methods of use |
| US20230057350A1 (en) | 2019-01-31 | 2023-02-23 | Hangzhou Dac Biotech Co., Ltd. | A conjugate of an amanita toxin with branched linkers |
| MA55372A (fr) | 2019-03-21 | 2022-01-26 | Regeneron Pharma | Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie |
| CN120053667A (zh) | 2019-03-25 | 2025-05-30 | 阿特根公司 | 用于皮下注射的包含人透明质酸酶ph20变体和药物的药物组合物 |
| AU2020301115B2 (en) | 2019-06-24 | 2024-05-23 | Hangzhou Dac Biotech Co., Ltd | A formulation of a conjugate of a tubulysin analog to a cell-binding molecule |
| MX2021015887A (es) | 2019-06-24 | 2022-03-22 | Hangzhou Dac Biotech Co Ltd | Un conjugado de un agente citotóxico y una molécula de unión a células con enlazadores ramificados. |
| EP4021499A4 (fr) | 2019-08-29 | 2024-08-07 | Elanco US Inc. | Anticorps anti-il31 à usage vétérinaire |
| WO2021115240A1 (fr) | 2019-12-13 | 2021-06-17 | 四川科伦博泰生物医药股份有限公司 | Anticorps anti-tslp et utilisations de celui-ci |
| CN114829396A (zh) | 2019-12-20 | 2022-07-29 | 英特维特国际股份有限公司 | 用于治疗特应性皮炎的双特异性犬源化抗体和双特异性结合伴体 |
| JP2023513952A (ja) | 2020-02-19 | 2023-04-04 | アディボ ゲーエムベーハー | 改変Fc領域 |
| MX2022011335A (es) | 2020-03-18 | 2022-10-07 | Kindred Biosciences Inc | Anticuerpos del receptor anti-interleucina 4 para uso veterinario. |
| PH12022552742A1 (en) | 2020-04-17 | 2024-03-25 | Zoetis Services Llc | Canine antibody variants |
| US20240270819A1 (en) | 2020-04-22 | 2024-08-15 | Elanco Us Inc. | Il4/il13 receptor molecules for veterinary use |
| CA3173864A1 (fr) | 2020-04-22 | 2021-10-28 | Shyr Jiann Li | Anticorps anti-il31 a action prolongee a usage veterinaire |
| US20230241241A1 (en) | 2020-06-19 | 2023-08-03 | Hangzhou Dac Biotech Co., Ltd. | Conjugates of a cell-binding molecule with camptothecin analogs |
| WO2022010652A1 (fr) | 2020-07-10 | 2022-01-13 | Invetx Inc. | Compositions permettant d'augmenter la demi-vie d'un agent thérapeutique chez les félins et procédés d'utilisation |
| GB202012331D0 (en) | 2020-08-07 | 2020-09-23 | Petmedix Ltd | Therapeutic antibodies |
| IL300694A (en) | 2020-09-01 | 2023-04-01 | Chugai Pharmaceutical Co Ltd | A pharmaceutical preparation for the prevention and/or treatment of dialysis pruritus that includes an IL-31 antagonist as an active ingredient |
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