MA47692A - Inhibiteurs de l'intégrine (alpha-v) (bêta-6) - Google Patents

Inhibiteurs de l'intégrine (alpha-v) (bêta-6)

Info

Publication number
MA47692A
MA47692A MA047692A MA47692A MA47692A MA 47692 A MA47692 A MA 47692A MA 047692 A MA047692 A MA 047692A MA 47692 A MA47692 A MA 47692A MA 47692 A MA47692 A MA 47692A
Authority
MA
Morocco
Prior art keywords
integrin
inhibitors
beta
alpha
Prior art date
Application number
MA047692A
Other languages
English (en)
Inventor
Matthew Gregory Bursavich
Aleksey Lgorevich Gerasyuto
Kristopher Neil Hahn
Bryce Alden Harrison
Kyle David Konze
fu-yang Lin
Blaise Scott Lippa
Alexey Alexandrovich Lugovskoy
Bruce Nelsen Rogers
Mats Ake Svensson
Dawn Marie Troast
Original Assignee
Morphic Therapeutic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphic Therapeutic Inc filed Critical Morphic Therapeutic Inc
Publication of MA47692A publication Critical patent/MA47692A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA047692A 2017-02-28 2018-02-27 Inhibiteurs de l'intégrine (alpha-v) (bêta-6) MA47692A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762465047P 2017-02-28 2017-02-28

Publications (1)

Publication Number Publication Date
MA47692A true MA47692A (fr) 2020-01-08

Family

ID=63371319

Family Applications (2)

Application Number Title Priority Date Filing Date
MA052117A MA52117A (fr) 2017-02-28 2018-02-27 Inhibiteurs de l'intégrine (alpha-v) (bêta-6)
MA047692A MA47692A (fr) 2017-02-28 2018-02-27 Inhibiteurs de l'intégrine (alpha-v) (bêta-6)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA052117A MA52117A (fr) 2017-02-28 2018-02-27 Inhibiteurs de l'intégrine (alpha-v) (bêta-6)

Country Status (6)

Country Link
US (4) US11046685B2 (fr)
EP (3) EP4147698A1 (fr)
AU (3) AU2018227417B2 (fr)
CA (1) CA3054792A1 (fr)
MA (2) MA52117A (fr)
WO (1) WO2018160522A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3509590A4 (fr) 2016-09-07 2020-12-02 Pliant Therapeutics, Inc. Composés d'acides aminés n-acyle et méthodes d'utilisation
US10696672B2 (en) 2016-12-23 2020-06-30 Pliant Therapeutics, Inc. Amino acid compounds and methods of use
US11306084B2 (en) 2016-12-29 2022-04-19 Saint Louis University Integrin antagonists
MA52117A (fr) 2017-02-28 2022-04-06 Morphic Therapeutic Inc Inhibiteurs de l'intégrine (alpha-v) (bêta-6)
MX394210B (es) 2017-02-28 2025-03-04 Morphic Therapeutic Inc INHIBIDORES DE INTEGRINA AVß6.
FI3761980T3 (fi) 2018-03-07 2024-02-21 Pliant Therapeutics Inc Aminohappoyhdisteitä ja käyttömenetelmiä
TWI841573B (zh) 2018-06-27 2024-05-11 美商普萊恩醫療公司 具有未分支連接子之胺基酸化合物及使用方法
SI3844162T1 (sl) 2018-08-29 2025-06-30 Morphic Therapeutic, Inc. Zaviralci integrina alfa v beta6
WO2020047239A1 (fr) 2018-08-29 2020-03-05 Morphic Therapeutic, Inc. INHIBITION DE L'INTÉGRINE ανβ6
WO2020047208A1 (fr) 2018-08-29 2020-03-05 Morphic Therapeutic, Inc. Inhibiteurs de l'intégrine (alpha-v)(bêta-6)
TW202028179A (zh) 2018-10-08 2020-08-01 美商普萊恩醫療公司 胺基酸化合物及使用方法
ES3013256T3 (en) 2018-10-30 2025-04-11 Gilead Sciences Inc Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases
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JP7189368B2 (ja) 2018-10-30 2022-12-13 ギリアード サイエンシーズ， インコーポレイテッド アルファ４ベータ７インテグリンの阻害のための化合物
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CN113354635B (zh) * 2020-03-06 2023-04-18 清药同创(北京)药物研发中心有限公司 一种吡咯烷类整合素调节剂及其用途
WO2022022364A1 (fr) * 2020-07-29 2022-02-03 清药同创(北京)药物研发中心有限公司 Modulateur de l'intégrine pyrrolidine et son utilisation
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KR20230169979A (ko) * 2021-03-10 2023-12-18 다이스 몰레큘스 에스브이, 인크. 알파 v 베타 6 및 알파 v 베타 1 인테그린 억제제 및 그의 용도

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MX394210B (es) 2017-02-28 2025-03-04 Morphic Therapeutic Inc INHIBIDORES DE INTEGRINA AVß6.
MA52117A (fr) 2017-02-28 2022-04-06 Morphic Therapeutic Inc Inhibiteurs de l'intégrine (alpha-v) (bêta-6)
FI3761980T3 (fi) 2018-03-07 2024-02-21 Pliant Therapeutics Inc Aminohappoyhdisteitä ja käyttömenetelmiä
TWI841573B (zh) 2018-06-27 2024-05-11 美商普萊恩醫療公司 具有未分支連接子之胺基酸化合物及使用方法
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WO2020047239A1 (fr) 2018-08-29 2020-03-05 Morphic Therapeutic, Inc. INHIBITION DE L'INTÉGRINE ανβ6
WO2020047207A1 (fr) 2018-08-29 2020-03-05 Morphic Therapeutics, Inc. Inhibiteurs de l'intégrine (alpha-v)(bêta -6)
TW202028179A (zh) 2018-10-08 2020-08-01 美商普萊恩醫療公司 胺基酸化合物及使用方法
CN114173803A (zh) 2019-04-08 2022-03-11 普利安特治疗公司 氨基酸化合物的剂型和方案

Also Published As

Publication number Publication date
AU2018227417B2 (en) 2021-12-23
CA3054792A1 (fr) 2018-09-07
US11795167B2 (en) 2023-10-24
US20240116929A1 (en) 2024-04-11
US20210284640A1 (en) 2021-09-16
WO2018160522A1 (fr) 2018-09-07
AU2022201929B2 (en) 2024-03-21
US12145935B2 (en) 2024-11-19
MA52117A (fr) 2022-04-06
US20250223289A1 (en) 2025-07-10
AU2022201929A1 (en) 2022-04-14
EP3589285A4 (fr) 2020-08-12
EP4147698A1 (fr) 2023-03-15
AU2018227417A1 (en) 2019-09-19
AU2024202105A1 (en) 2024-05-02
AU2024202105B2 (en) 2026-01-29
EP3760202A1 (fr) 2021-01-06
US20200002334A1 (en) 2020-01-02
US11046685B2 (en) 2021-06-29
EP3589285A1 (fr) 2020-01-08

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