MA48944A - Forme cristalline de n-butyldéoxygalactonojirimycine - Google Patents

Forme cristalline de n-butyldéoxygalactonojirimycine

Info

Publication number
MA48944A
MA48944A MA048944A MA48944A MA48944A MA 48944 A MA48944 A MA 48944A MA 048944 A MA048944 A MA 048944A MA 48944 A MA48944 A MA 48944A MA 48944 A MA48944 A MA 48944A
Authority
MA
Morocco
Prior art keywords
butyldeoxygalactonojirimycin
crystalline form
crystalline
butyldeoxygalactonojirimycin crystalline
Prior art date
Application number
MA048944A
Other languages
English (en)
Other versions
MA48944B1 (fr
Inventor
Vitor Oliveira
Ivan Pogorelic
Jean-Paul Roduit
Original Assignee
Idorsia Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd
Publication of MA48944A publication Critical patent/MA48944A/fr
Publication of MA48944B1 publication Critical patent/MA48944B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
MA48944A 2017-06-01 2018-05-31 Forme cristalline de n-butyldéoxygalactonojirimycine MA48944B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2017063287 2017-06-01
PCT/EP2018/064365 WO2018220131A1 (fr) 2017-06-01 2018-05-31 Forme cristalline de n-butyldéoxygalactonojirimycine
EP18728624.0A EP3630725B1 (fr) 2017-06-01 2018-05-31 Forme cristalline de n-butyldéoxygalactonojirimycine

Publications (2)

Publication Number Publication Date
MA48944A true MA48944A (fr) 2020-04-08
MA48944B1 MA48944B1 (fr) 2025-12-31

Family

ID=62492649

Family Applications (1)

Application Number Title Priority Date Filing Date
MA48944A MA48944B1 (fr) 2017-06-01 2018-05-31 Forme cristalline de n-butyldéoxygalactonojirimycine

Country Status (27)

Country Link
US (2) US11306058B2 (fr)
EP (1) EP3630725B1 (fr)
JP (2) JP6937850B2 (fr)
KR (1) KR102612650B1 (fr)
CN (1) CN110799497A (fr)
AU (1) AU2018278247B2 (fr)
CA (1) CA3065147A1 (fr)
CL (1) CL2019003478A1 (fr)
DK (1) DK3630725T3 (fr)
EA (1) EA201992807A1 (fr)
ES (1) ES3059191T3 (fr)
FI (1) FI3630725T3 (fr)
HR (1) HRP20251697T1 (fr)
IL (1) IL270961B2 (fr)
LT (1) LT3630725T (fr)
MA (1) MA48944B1 (fr)
MX (1) MX2019014427A (fr)
MY (1) MY201196A (fr)
NZ (1) NZ760100A (fr)
PH (1) PH12019502635A1 (fr)
PL (1) PL3630725T3 (fr)
PT (1) PT3630725T (fr)
RS (1) RS67675B1 (fr)
SI (1) SI3630725T1 (fr)
TW (1) TWI770184B (fr)
UA (1) UA125938C2 (fr)
WO (1) WO2018220131A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20251697T1 (hr) * 2017-06-01 2026-02-27 Idorsia Pharmaceuticals Ltd Kristalni oblik n-butildeoksigalaktonojirimicina
ES3062389T3 (en) 2019-09-25 2026-04-10 Assia Chem Ind Ltd Solid state forms of lucerastat salts and process for preparation thereof
WO2025017212A1 (fr) 2023-07-20 2025-01-23 Katholieke Universiteit Leuven Inhibiteurs de synthase de glucosyltransférase de céramide d'udp-glucose (ugcg) dans le traitement du cancer
TR2024011149A1 (tr) * 2024-08-23 2026-03-23 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Mi̇galastat i̇çeren kapsül formülasyonlari

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0536402A4 (en) * 1990-06-29 1993-05-12 Nippon Shinyaku Company, Limited Piperidine derivative
US6291657B1 (en) * 1993-05-13 2001-09-18 Monsanto Company Deoxygalactonojirimycin derivatives
US6274597B1 (en) 1998-06-01 2001-08-14 Mount Sinai School Of Medicine Of New York University Method of enhancing lysosomal α-Galactosidase A
GB0100889D0 (en) 2001-01-12 2001-02-21 Oxford Glycosciences Uk Ltd Compounds
GB0229476D0 (en) * 2002-12-17 2003-01-22 Oxford Glycosciences Uk Ltd Novel process
FR2861991B1 (fr) * 2003-11-07 2008-01-18 Centre Nat Rech Scient Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose
WO2006037069A1 (fr) 2004-09-28 2006-04-06 Allergan, Inc. Compositions comprenant nb-dnj, ne-dnj ou d-glucaro-delta-lactame et leurs utilisations pour le traitement de la douleur et autres etats neurologiques
EP3782655A1 (fr) 2005-05-17 2021-02-24 Amicus Therapeutics, Inc. Procédé pour le traitement de la maladie de pompe au moyen de 1-désoxynojirimycine et de ses dérivés
CN101267779A (zh) 2005-07-27 2008-09-17 福罗里达大学研究基金会有限公司 使用热休克治疗眼睛疾病
DE602007008870D1 (de) 2006-04-24 2010-10-14 Amc Amsterdam Verbessertes verfahren zur behandlung von cystischer fibrose
GB0712494D0 (en) 2007-06-27 2007-08-08 Isis Innovation Substrate reduction therapy
ITMI20122090A1 (it) 2012-12-06 2014-06-07 Dipharma Francis Srl Sintesi di un inibitore delle glicosiltransferasi
HRP20251697T1 (hr) * 2017-06-01 2026-02-27 Idorsia Pharmaceuticals Ltd Kristalni oblik n-butildeoksigalaktonojirimicina

Also Published As

Publication number Publication date
FI3630725T3 (fi) 2026-01-27
UA125938C2 (uk) 2022-07-13
US20220002245A1 (en) 2022-01-06
RS67675B1 (sr) 2026-02-27
TW201902876A (zh) 2019-01-16
TWI770184B (zh) 2022-07-11
BR112019025125A2 (pt) 2020-07-21
AU2018278247B2 (en) 2022-07-28
IL270961A (en) 2020-01-30
AU2018278247A1 (en) 2020-01-16
IL270961B1 (en) 2024-11-01
KR102612650B1 (ko) 2023-12-11
JP2020521796A (ja) 2020-07-27
CL2019003478A1 (es) 2020-06-05
US11306058B2 (en) 2022-04-19
MA48944B1 (fr) 2025-12-31
PL3630725T3 (pl) 2026-03-23
PH12019502635A1 (en) 2020-07-13
JP6937850B2 (ja) 2021-09-22
EP3630725B1 (fr) 2025-10-29
NZ760100A (en) 2026-03-27
WO2018220131A1 (fr) 2018-12-06
LT3630725T (lt) 2026-01-12
IL270961B2 (en) 2025-03-01
US11713297B2 (en) 2023-08-01
US20200140385A1 (en) 2020-05-07
CA3065147A1 (fr) 2018-12-06
JP2021185184A (ja) 2021-12-09
EA201992807A1 (ru) 2020-05-20
MY201196A (en) 2024-02-09
HRP20251697T1 (hr) 2026-02-27
SI3630725T1 (sl) 2026-01-30
JP7373529B2 (ja) 2023-11-02
DK3630725T3 (da) 2026-02-09
EP3630725A1 (fr) 2020-04-08
CN110799497A (zh) 2020-02-14
MX2019014427A (es) 2020-02-05
ES3059191T3 (en) 2026-03-19
KR20200011992A (ko) 2020-02-04
PT3630725T (pt) 2026-01-27

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