MA49703A - Nouveaux intermédiaires utiles pour la synthèse de dérivés d'aminopyrimidine, leur procédé de préparation et procédé de préparation de dérivés d'aminopyrimidine à l'aide de ceux-ci - Google Patents
Nouveaux intermédiaires utiles pour la synthèse de dérivés d'aminopyrimidine, leur procédé de préparation et procédé de préparation de dérivés d'aminopyrimidine à l'aide de ceux-ciInfo
- Publication number
- MA49703A MA49703A MA049703A MA49703A MA49703A MA 49703 A MA49703 A MA 49703A MA 049703 A MA049703 A MA 049703A MA 49703 A MA49703 A MA 49703A MA 49703 A MA49703 A MA 49703A
- Authority
- MA
- Morocco
- Prior art keywords
- preparation
- aminopyrimidine derivatives
- synthesis
- new useful
- aminopyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Health & Medical Sciences (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170096220 | 2017-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA49703A true MA49703A (fr) | 2021-04-21 |
Family
ID=65040817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA049703A MA49703A (fr) | 2017-07-28 | 2018-07-25 | Nouveaux intermédiaires utiles pour la synthèse de dérivés d'aminopyrimidine, leur procédé de préparation et procédé de préparation de dérivés d'aminopyrimidine à l'aide de ceux-ci |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US10858353B2 (fr) |
| EP (1) | EP3658553B1 (fr) |
| JP (1) | JP7216704B2 (fr) |
| KR (1) | KR102684954B1 (fr) |
| CN (1) | CN111032650A (fr) |
| AU (1) | AU2018308039B2 (fr) |
| CA (1) | CA3069408A1 (fr) |
| CO (1) | CO2020000595A2 (fr) |
| CY (1) | CY1125473T1 (fr) |
| DK (1) | DK3658553T3 (fr) |
| EA (1) | EA038856B1 (fr) |
| ES (1) | ES2923278T3 (fr) |
| HR (1) | HRP20220848T1 (fr) |
| HU (1) | HUE059501T2 (fr) |
| IL (1) | IL271974B (fr) |
| LT (1) | LT3658553T (fr) |
| MA (1) | MA49703A (fr) |
| MX (1) | MX394027B (fr) |
| MY (1) | MY200829A (fr) |
| PH (1) | PH12020500070A1 (fr) |
| PL (1) | PL3658553T3 (fr) |
| PT (1) | PT3658553T (fr) |
| RS (1) | RS63497B1 (fr) |
| SA (1) | SA520411120B1 (fr) |
| SG (1) | SG11201913520YA (fr) |
| SI (1) | SI3658553T1 (fr) |
| SM (1) | SMT202200291T1 (fr) |
| UA (1) | UA125664C2 (fr) |
| WO (1) | WO2019022486A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX393995B (es) | 2017-07-28 | 2025-03-24 | Yuhan Corp | Proceso mejorado para preparar derivados de aminopirimidina |
| US11850248B2 (en) | 2019-05-14 | 2023-12-26 | Yuhan Corporation | Therapies with 3rd generation EGFR tyrosine kinase inhibitors |
| JOP20210304A1 (ar) | 2019-05-14 | 2023-01-30 | Janssen Biotech Inc | علاجات مركبة باستخدام الأجسام المضادة ثنائية النوعية المضادة لمستقبل عامل نمو البشرة (EGFR)/ مستقبل عامل نمو خلايا الكبد (c-Met) ومثبطات كيناز التيروسين الخاصة بمستقبل عامل نمو البشرة (EGFR) من الجيل الثالث |
| JOP20220184A1 (ar) | 2020-02-12 | 2023-01-30 | Janssen Biotech Inc | علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14 |
| TW202207940A (zh) | 2020-04-14 | 2022-03-01 | 美商健生生物科技公司 | 包含胺基嘧啶衍生物或其醫藥上可接受之鹽、水合物、或溶劑化物之用於經口投予之醫藥組成物 |
| CA3228195A1 (en) | 2023-05-23 | 2025-06-30 | Janssen Biotech, Inc. | Methods for treatment of non-small cell lung cancer (nsclc) |
| WO2025052273A1 (fr) | 2023-09-05 | 2025-03-13 | Janssen Biotech, Inc. | Méthodes pour traiter le cancer du poumon non à petites cellules |
| WO2026042017A1 (fr) | 2024-08-19 | 2026-02-26 | Janssen Biotech, Inc. | Amivantamab en association avec le lazertinib pour le traitement du cancer du poumon non à petites cellules (cpnpc) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5740409B2 (ja) * | 2009-11-13 | 2015-06-24 | ジェノスコ | キナーゼ阻害剤 |
| CN105461695B (zh) * | 2014-09-29 | 2018-03-27 | 齐鲁制药有限公司 | 嘧啶或三嗪衍生物及其制备方法和用途 |
| MX2017003181A (es) * | 2014-10-13 | 2017-07-20 | Yuhan Corp | Compuestos y composiciones para modular actividades de quinasa de mutante de receptor del factor de crecimiento epidermico. |
| CN104788427B (zh) * | 2015-02-05 | 2017-05-31 | 上海泓博智源医药股份有限公司 | 3‑(2‑嘧啶氨基)苯基丙烯酰胺类化合物及其应用 |
| JP6457697B2 (ja) * | 2015-04-29 | 2019-01-23 | カントン チョンション ファーマシューティカル カンパニー，リミティド | キナーゼ阻害剤としての縮合環式または三環式アリールピリミジン化合物 |
| US10329257B2 (en) * | 2015-08-13 | 2019-06-25 | The Broad Institute, Inc. | Compositions and methods for treating tuberculosis |
| CN111295381A (zh) * | 2017-07-28 | 2020-06-16 | 株式会社柳韩洋行 | 可用于合成抗蛋白激酶的选择性抑制剂的中间体及其制备方法 |
-
2018
- 2018-07-25 DK DK18838173.5T patent/DK3658553T3/da active
- 2018-07-25 EP EP18838173.5A patent/EP3658553B1/fr active Active
- 2018-07-25 JP JP2020503944A patent/JP7216704B2/ja active Active
- 2018-07-25 SG SG11201913520YA patent/SG11201913520YA/en unknown
- 2018-07-25 HU HUE18838173A patent/HUE059501T2/hu unknown
- 2018-07-25 UA UAA202001305A patent/UA125664C2/uk unknown
- 2018-07-25 US US16/633,695 patent/US10858353B2/en active Active
- 2018-07-25 SI SI201830722T patent/SI3658553T1/sl unknown
- 2018-07-25 CN CN201880049025.7A patent/CN111032650A/zh active Pending
- 2018-07-25 MX MX2020001047A patent/MX394027B/es unknown
- 2018-07-25 RS RS20220706A patent/RS63497B1/sr unknown
- 2018-07-25 WO PCT/KR2018/008381 patent/WO2019022486A1/fr not_active Ceased
- 2018-07-25 MY MYPI2020000439A patent/MY200829A/en unknown
- 2018-07-25 PT PT188381735T patent/PT3658553T/pt unknown
- 2018-07-25 CA CA3069408A patent/CA3069408A1/fr active Pending
- 2018-07-25 IL IL271974A patent/IL271974B/en unknown
- 2018-07-25 KR KR1020180086377A patent/KR102684954B1/ko active Active
- 2018-07-25 PL PL18838173.5T patent/PL3658553T3/pl unknown
- 2018-07-25 LT LTEPPCT/KR2018/008381T patent/LT3658553T/lt unknown
- 2018-07-25 EA EA202090385A patent/EA038856B1/ru unknown
- 2018-07-25 MA MA049703A patent/MA49703A/fr unknown
- 2018-07-25 AU AU2018308039A patent/AU2018308039B2/en active Active
- 2018-07-25 HR HRP20220848TT patent/HRP20220848T1/hr unknown
- 2018-07-25 SM SM20220291T patent/SMT202200291T1/it unknown
- 2018-07-25 ES ES18838173T patent/ES2923278T3/es active Active
-
2020
- 2020-01-09 PH PH12020500070A patent/PH12020500070A1/en unknown
- 2020-01-20 CO CONC2020/0000595A patent/CO2020000595A2/es unknown
- 2020-01-22 SA SA520411120A patent/SA520411120B1/ar unknown
-
2022
- 2022-08-05 CY CY20221100537T patent/CY1125473T1/el unknown
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