MA49959A - Formulation liposomale pour lubrification d'articulation - Google Patents

Formulation liposomale pour lubrification d'articulation

Info

Publication number: MA49959A
Authority: MA; Morocco
Prior art keywords: liposomal formulation; joint lubrication; lubrication; joint; liposomal
Prior art date: 2017-08-22

Application number

MA049959A

Other languages

English (en)

Other versions

MA49959B1 (fr

Inventor

Maty Ayal-Hershkovitz

Yechezkel Barenholz

Yaniv Dolev

Gadi Sarfati

Keren Turjeman

Original Assignee

Moebius Medical Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-08-22

Filing date

2018-08-21

Publication date

2020-07-01

2018-08-21 Application filed by Moebius Medical Ltd filed Critical Moebius Medical Ltd

2020-07-01 Publication of MA49959A publication Critical patent/MA49959A/fr

2023-07-31 Publication of MA49959B1 publication Critical patent/MA49959B1/fr

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/10—Materials for lubricating medical devices
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Biochemistry (AREA)
Dispersion Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

MA49959A 2017-08-22 2018-08-21 Formulation liposomale pour lubrification d'articulation MA49959B1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201762548429P	2017-08-22	2017-08-22
PCT/IL2018/050923 WO2019038763A1 (fr)	2017-08-22	2018-08-21	Formulation liposomale pour lubrification d'articulation

Publications (2)

Publication Number	Publication Date
MA49959A true MA49959A (fr)	2020-07-01
MA49959B1 MA49959B1 (fr)	2023-07-31

Family

ID=65439381

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA49959A MA49959B1 (fr)	2017-08-22	2018-08-21	Formulation liposomale pour lubrification d'articulation

Country Status (25)

Country	Link
US (3)	US11123293B2 (fr)
EP (2)	EP3672653B1 (fr)
JP (2)	JP7082336B2 (fr)
KR (2)	KR102607729B1 (fr)
CN (2)	CN111065423B (fr)
AU (3)	AU2018319594B2 (fr)
BR (1)	BR112020003767B1 (fr)
CA (2)	CA3073368C (fr)
DK (1)	DK3672653T3 (fr)
EA (1)	EA202090476A1 (fr)
ES (1)	ES2948715T3 (fr)
FI (1)	FI3672653T3 (fr)
HR (1)	HRP20230566T1 (fr)
HU (1)	HUE062030T2 (fr)
IL (3)	IL301801B2 (fr)
LT (1)	LT3672653T (fr)
MA (1)	MA49959B1 (fr)
MX (2)	MX2020002041A (fr)
MY (1)	MY197149A (fr)
PH (1)	PH12020500331A1 (fr)
PL (1)	PL3672653T3 (fr)
PT (1)	PT3672653T (fr)
SG (1)	SG11202000773QA (fr)
SI (1)	SI3672653T1 (fr)
WO (1)	WO2019038763A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI782181B (zh) *	2019-02-11	2022-11-01	以色列商莫比斯醫療有限公司	用於關節潤滑的脂質體調配物
JP2021013788A (ja) *	2020-11-10	2021-02-12	株式会社三洋物産	遊技機
AU2022425700A1 (en) *	2022-01-02	2024-07-18	Moebius Medical Ltd.	Determination of the trapped volume of a liposome
EP4522178A1 (fr)	2023-01-19	2025-03-19	Moebius Medical Ltd.	Composition liposomale à action prolongée pour le traitement de la douleur dans des troubles articulaires
KR20250018222A (ko) *	2023-07-26	2025-02-05	차의과학대학교 산학협력단	미토콘드리아가 캡슐화된 세포막 융합유도 리포좀을 포함하는 골관절염 치료를 위한 약학 조성물
IL314549A (en) *	2024-07-25	2026-02-01	Moebius Medical Ltd	Liposomal conjugates and their uses

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US5403592A (en)	1987-08-25	1995-04-04	Macnaught Pty Limited	Lubricant composition for rheumatism
EP0319638A1 (fr) *	1987-12-08	1989-06-14	Estee Lauder Inc.	Compositions cosmétiques et pharmaceutiques contenant des liposomes et procédés pour l'utilisation de telles compositions
US5941909A (en) *	1995-02-14	1999-08-24	Mentor Corporation	Filling material for soft tissue implant prostheses and implants made therewith
AUPN723395A0 (en)	1995-12-19	1996-01-18	Macnaught Medical Pty Limited	Lubrication methods
US6379648B1 (en) *	1999-02-01	2002-04-30	The Curators Of The University Of Missouri	Biodegradable glass compositions and methods for radiation therapy
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JP2004521112A (ja) *	2001-01-24	2004-07-15	メステックスアクチエンゲゼルシャフト	関節痛治療薬を製造することへの神経毒性物質の使用
US6509027B2 (en) *	2001-02-12	2003-01-21	Supergen, Inc.	Injectable pharmaceutical composition comprising coated particles of camptothecin
ATE424111T1 (de)	2001-03-29	2009-03-15	Scripps Research Inst	Formulierungen, die eingeschlossene wirkstoffe enthalten, und ihre verwendung
CA2451248A1 (fr)	2001-06-25	2003-01-03	Depuy International Limited	Composition comprenant des glycosaminoglycanes et des inhibiteurs d'hyaluronidase destinee au traitement d'articulations arthritiques
IL159334A0 (en) *	2001-06-25	2004-06-01	Yissum Res Dev Co	A method for preparation of vesicles loaded with biological material and different uses thereof
CA2451245A1 (fr)	2001-06-25	2003-01-03	Depuy International Limited	Encapsulation liposomale de glycosaminoglycanes pour le traitement d'articulations arthrosees
DE10255106A1 (de)	2002-11-24	2004-06-09	Novosom Ag	Liposomale Glucocorticoide
US7205006B2 (en)	2003-09-25	2007-04-17	Prime Pharmaceutical Corporation	Mahonia aquifolium extract, extraction process and pharmaceutical composition containing the same
EP1750671B1 (fr)	2004-06-03	2008-10-15	Bracco Research S.A.	Assemblage liposomale pour son utilisation therapeutique et/ou diagnostique
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US20070071840A1 (en)	2005-09-27	2007-03-29	Sridevi Dhanaraj	Method for treatment of cartilage disorders with centella extract
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ES2599630T3 (es)	2006-09-28	2017-02-02	Hadasit Medical Research Services & Development Limited	Uso de glicerofosfolípidos para lubricación de las articulaciones
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JP2011512409A (ja)	2008-02-20	2011-04-21	イーエルシーマネージメントエルエルシー	皮膚を美白するための局所組成物及び方法
BR112012032153A2 (pt)	2010-06-17	2017-08-08	Yeda Res And Development Company Ltd	método para a lubrificação de uma ou mais superfícies não biológicas, método para a lubrificação de uma ou mais superfícies de um tecido biológico em um indivíduo mamífero, uso de lipossomas na fase em gel e lipossoma misto
IL206739A (en) *	2010-06-30	2016-06-30	David Segal	An injectable drug containing silitol as an active substance
US20140038917A1 (en)	2011-04-19	2014-02-06	Anteis S.A.	Sterile and injectable aqueous formulation for administration in the intra-articular space of an intra-articular joint
US8623839B2 (en)	2011-06-30	2014-01-07	Depuy Mitek, Llc	Compositions and methods for stabilized polysaccharide formulations
GB201206486D0 (en)	2012-04-12	2012-05-30	Sequessome Technology Holdings Ltd	Vesicular formulations and uses thereof
RU2677658C2 (ru) *	2012-07-05	2019-01-18	Тайвэн Липосом Ко, Лтд.	Способы лечения артрита
CN104688721A (zh)	2014-10-11	2015-06-10	黄萍	一种含紫杉醇脂质体的抗类风湿性关节炎药物凝胶剂及其制备方法

2018
- 2018-08-21 CN CN201880053772.8A patent/CN111065423B/zh active Active
- 2018-08-21 PT PT188474936T patent/PT3672653T/pt unknown
- 2018-08-21 WO PCT/IL2018/050923 patent/WO2019038763A1/fr not_active Ceased
- 2018-08-21 CN CN202210282704.7A patent/CN114601799B/zh active Active
- 2018-08-21 EP EP18847493.6A patent/EP3672653B1/fr active Active
- 2018-08-21 FI FIEP18847493.6T patent/FI3672653T3/fi active
- 2018-08-21 MY MYPI2020000726A patent/MY197149A/en unknown
- 2018-08-21 IL IL301801A patent/IL301801B2/en unknown
- 2018-08-21 SG SG11202000773QA patent/SG11202000773QA/en unknown
- 2018-08-21 HR HRP20230566TT patent/HRP20230566T1/hr unknown
- 2018-08-21 BR BR112020003767-2A patent/BR112020003767B1/pt active IP Right Grant
- 2018-08-21 KR KR1020207006061A patent/KR102607729B1/ko active Active
- 2018-08-21 EP EP23160029.7A patent/EP4223284A1/fr active Pending
- 2018-08-21 MX MX2020002041A patent/MX2020002041A/es unknown
- 2018-08-21 IL IL272630A patent/IL272630B2/en unknown
- 2018-08-21 HU HUE18847493A patent/HUE062030T2/hu unknown
- 2018-08-21 US US16/337,188 patent/US11123293B2/en active Active
- 2018-08-21 CA CA3073368A patent/CA3073368C/fr active Active
- 2018-08-21 CA CA3219776A patent/CA3219776A1/fr active Pending
- 2018-08-21 SI SI201830942T patent/SI3672653T1/sl unknown
- 2018-08-21 IL IL312816A patent/IL312816B1/en unknown
- 2018-08-21 PL PL18847493.6T patent/PL3672653T3/pl unknown
- 2018-08-21 DK DK18847493.6T patent/DK3672653T3/da active
- 2018-08-21 EA EA202090476A patent/EA202090476A1/ru unknown
- 2018-08-21 AU AU2018319594A patent/AU2018319594B2/en active Active
- 2018-08-21 JP JP2020511447A patent/JP7082336B2/ja active Active
- 2018-08-21 MA MA49959A patent/MA49959B1/fr unknown
- 2018-08-21 LT LTEPPCT/IL2018/050923T patent/LT3672653T/lt unknown
- 2018-08-21 ES ES18847493T patent/ES2948715T3/es active Active
- 2018-08-21 KR KR1020237040609A patent/KR102808544B1/ko active Active
2020
- 2020-02-13 PH PH12020500331A patent/PH12020500331A1/en unknown
- 2020-02-21 MX MX2023009082A patent/MX2023009082A/es unknown
2021
- 2021-08-15 US US17/445,089 patent/US12214077B2/en active Active
2022
- 2022-05-17 JP JP2022080859A patent/JP7383759B2/ja active Active
2023
- 2023-05-26 AU AU2023203309A patent/AU2023203309B2/en active Active
2024
- 2024-12-17 US US18/984,974 patent/US20250114304A1/en active Pending
2025
- 2025-01-07 AU AU2025200077A patent/AU2025200077B2/en active Active

Also Published As

Publication number	Publication date
AU2023203309B2 (en)	2024-10-10
US20250114304A1 (en)	2025-04-10
HUE062030T2 (hu)	2023-09-28
MX2020002041A (es)	2020-08-13
IL312816B1 (en)	2026-02-01
CA3073368A1 (fr)	2019-02-28
PL3672653T3 (pl)	2023-08-14
IL272630A (en)	2020-03-31
EP3672653A1 (fr)	2020-07-01
EP3672653B1 (fr)	2023-03-29
HRP20230566T1 (hr)	2023-08-18
FI3672653T3 (fi)	2023-06-07
CN111065423B (zh)	2022-04-12
SI3672653T1 (sl)	2023-08-31
PT3672653T (pt)	2023-06-29
MX2023009082A (es)	2023-08-08
CA3073368C (fr)	2024-01-02
NZ761298A (en)	2024-03-22
US12214077B2 (en)	2025-02-04
JP7082336B2 (ja)	2022-06-08
IL301801B2 (en)	2024-10-01
MY197149A (en)	2023-05-26
KR20200044006A (ko)	2020-04-28
CA3219776A1 (fr)	2019-02-28
BR112020003767B1 (pt)	2023-10-10
EP4223284A1 (fr)	2023-08-09
SG11202000773QA (en)	2020-03-30
CN114601799B (zh)	2023-09-26
EA202090476A1 (ru)	2020-06-29
ES2948715T3 (es)	2023-09-18
US11123293B2 (en)	2021-09-21
AU2023203309A1 (en)	2023-06-22
WO2019038763A1 (fr)	2019-02-28
US20210369613A1 (en)	2021-12-02
JP7383759B2 (ja)	2023-11-20
JP2020531538A (ja)	2020-11-05
EP3672653A4 (fr)	2021-01-13
PH12020500331A1 (en)	2020-10-05
IL301801B1 (en)	2024-06-01
LT3672653T (lt)	2023-07-10
AU2025200077A1 (en)	2025-01-23
MA49959B1 (fr)	2023-07-31
US20200170948A1 (en)	2020-06-04
IL272630B2 (en)	2023-09-01
CN114601799A (zh)	2022-06-10
IL312816A (en)	2024-07-01
DK3672653T3 (da)	2023-06-12
JP2022110090A (ja)	2022-07-28
AU2018319594B2 (en)	2023-06-15
BR112020003767A2 (pt)	2020-09-01
AU2025200077B2 (en)	2026-01-08
KR20230166148A (ko)	2023-12-06
AU2018319594A1 (en)	2020-02-20
KR102607729B1 (ko)	2023-11-29
KR102808544B1 (ko)	2025-05-19
IL301801A (en)	2023-05-01
CN111065423A (zh)	2020-04-24
IL272630B1 (en)	2023-05-01

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