MA50279A - Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches - Google Patents

Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches

Info

Publication number
MA50279A
MA50279A MA050279A MA50279A MA50279A MA 50279 A MA50279 A MA 50279A MA 050279 A MA050279 A MA 050279A MA 50279 A MA50279 A MA 50279A MA 50279 A MA50279 A MA 50279A
Authority
MA
Morocco
Prior art keywords
cells
enrichment
expressing
peptide
stem cells
Prior art date
Application number
MA050279A
Other languages
English (en)
Inventor
Allé Novo
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MA50279A publication Critical patent/MA50279A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0677—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA050279A 2017-09-11 2018-09-11 Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches MA50279A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17190412 2017-09-11

Publications (1)

Publication Number Publication Date
MA50279A true MA50279A (fr) 2020-07-22

Family

ID=59846503

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050279A MA50279A (fr) 2017-09-11 2018-09-11 Enrichissement de cellules coexprimant nkx6.1 et le peptide c, dérivées in vitro à partir de cellules souches

Country Status (15)

Country Link
US (2) US20200199540A1 (fr)
EP (1) EP3681992A1 (fr)
JP (1) JP7389020B2 (fr)
KR (1) KR102738995B1 (fr)
CN (1) CN111108190B (fr)
AU (1) AU2018330499B2 (fr)
BR (1) BR112020004428A2 (fr)
CA (1) CA3074910A1 (fr)
CO (1) CO2020003122A2 (fr)
IL (1) IL272734B2 (fr)
MA (1) MA50279A (fr)
MX (1) MX2020002421A (fr)
SA (1) SA520411466B1 (fr)
SG (1) SG11202001906PA (fr)
WO (1) WO2019048690A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3953451A1 (fr) 2019-04-08 2022-02-16 Novo Nordisk A/S Production d'endoderme pancréatique à partir d'endoderme définitif dérivé de cellules souches
JP2023503302A (ja) 2019-11-22 2023-01-27 ノヴォ ノルディスク アー／エス スピン凝集した神経系マイクロスフェアおよびその応用
US20250283046A1 (en) 2022-04-21 2025-09-11 Evotec International Gmbh New Cell Populations and Means and Methods for their Differentiation and Preservation
WO2024008810A1 (fr) 2022-07-06 2024-01-11 Novo Nordisk A/S Différenciation de cellules souches en cellules endocrines pancréatiques
IL328729A (en) 2023-12-01 2026-07-01 Sigilon Therapeutics Inc Methods for producing stem cell-derived islet-like cells, as well as populations and compositions comprising them
EP4491712A1 (fr) 2024-03-20 2025-01-15 Novo Nordisk A/S Procédé de détection de cellules contaminantes dans une population de cellules dérivées de cellules souches

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2018638C (fr) * 1990-06-08 2002-10-01 Wah Jun Tze Mise en banque de cellules endocrines de pancreas pour les transplantations
CN1671835A (zh) 2001-12-28 2005-09-21 塞拉提斯股份公司 一种建立多能人胚泡衍生的干细胞的方法
WO2007042225A2 (fr) 2005-10-07 2007-04-19 Cellartis Ab Procede pour l'obtention d'une lignee cellulaire hbs exempte de xeno-contaminants
US7695965B2 (en) * 2006-03-02 2010-04-13 Cythera, Inc. Methods of producing pancreatic hormones
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
EP2356227B1 (fr) * 2008-11-14 2018-03-28 Viacyte, Inc. Encapsulation de cellules pancréatiques dérivées de cellules souches pluripotentes humaines
AU2011223900A1 (en) * 2010-03-01 2012-09-13 Janssen Biotech, Inc. Methods for purifying cells derived from pluripotent stem cells
WO2012175633A1 (fr) 2011-06-21 2012-12-27 Novo Nordisk A/S Induction efficace de l'endoderme definitif à partir de cellules souches pluripotentes
EP2893000B1 (fr) 2012-09-03 2019-04-10 Novo Nordisk A/S Génération d'endoderme pancréatique à partir de cellules souches pluripotentes à l'aide de petites molécules
DK2938722T3 (da) 2012-12-31 2022-02-14 Janssen Biotech Inc Suspension og klyngedannelse af humane pluripotente celler til differentiering til endokrine pankreasceller
WO2014138671A2 (fr) * 2013-03-08 2014-09-12 Viacyte, Inc. Cryopréservation, hibernation et stockage à température ambiante d'agrégats de cellules endodermiques pancréatiques encapsulés
US8859286B2 (en) * 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
DK3039122T3 (da) * 2013-08-30 2019-09-30 Novo Nordisk As Generering af endokrine progenitorceller fra humane pluripotente stamceller under anvendelse af små molekyler
JP2017112835A (ja) * 2014-04-17 2017-06-29 東京エレクトロン株式会社 多能性幹細胞の凍結保存方法および凍結保存システム
CN107250349A (zh) * 2014-12-19 2017-10-13 詹森生物科技公司 多能干细胞的悬浮培养
HK1254740A1 (zh) * 2015-11-30 2019-07-26 Kadimastem Ltd. 分化和纯化胰腺内分泌细胞的方法
EP3420073B1 (fr) 2016-02-24 2023-11-08 Novo Nordisk A/S Génération de cellules bêta fonctionnelles de cellules souches pluripotentes humaines à partir de cellules progénitrices endocrines
CA3027879A1 (fr) * 2016-06-21 2017-12-28 Janssen Biotech, Inc. Generation de cellules beta fonctionnelles derivees de cellules souches pluripotentes humaines ayant une respiration mitochondriale glucose-dependante et une reponse en secretiond'insuline en deux phases

Also Published As

Publication number Publication date
EP3681992A1 (fr) 2020-07-22
JP7389020B2 (ja) 2023-11-29
WO2019048690A1 (fr) 2019-03-14
SA520411466B1 (ar) 2024-03-10
BR112020004428A2 (pt) 2020-09-08
CN111108190A (zh) 2020-05-05
US20250043246A1 (en) 2025-02-06
CO2020003122A2 (es) 2020-06-19
IL272734B1 (en) 2025-01-01
CA3074910A1 (fr) 2019-03-14
IL272734B2 (en) 2025-05-01
MX2020002421A (es) 2020-07-13
CN111108190B (zh) 2024-06-21
JP2020532978A (ja) 2020-11-19
AU2018330499B2 (en) 2025-01-30
KR102738995B1 (ko) 2024-12-06
RU2020111055A (ru) 2021-09-17
IL272734A (en) 2020-04-30
SG11202001906PA (en) 2020-04-29
US20200199540A1 (en) 2020-06-25
KR20200051664A (ko) 2020-05-13
RU2020111055A3 (fr) 2022-04-22
AU2018330499A1 (en) 2020-04-09

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