MA51279A - Traitement de troubles autonomes par la toxine botulique - Google Patents

Traitement de troubles autonomes par la toxine botulique

Info

Publication number
MA51279A
MA51279A MA051279A MA51279A MA51279A MA 51279 A MA51279 A MA 51279A MA 051279 A MA051279 A MA 051279A MA 51279 A MA51279 A MA 51279A MA 51279 A MA51279 A MA 51279A
Authority
MA
Morocco
Prior art keywords
autonomous
disorders
treatment
botulin toxin
botulin
Prior art date
Application number
MA051279A
Other languages
English (en)
Inventor
Johannes Krupp
Jacquie Maignel-Ludol
Bernadette Pignol
Original Assignee
Ipsen Biopharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Biopharm Ltd filed Critical Ipsen Biopharm Ltd
Publication of MA51279A publication Critical patent/MA51279A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA051279A 2017-12-20 2018-12-20 Traitement de troubles autonomes par la toxine botulique MA51279A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17306840 2017-12-20

Publications (1)

Publication Number Publication Date
MA51279A true MA51279A (fr) 2021-03-31

Family

ID=61027399

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051279A MA51279A (fr) 2017-12-20 2018-12-20 Traitement de troubles autonomes par la toxine botulique

Country Status (21)

Country Link
US (2) US20200377872A1 (fr)
EP (2) EP3727429B1 (fr)
JP (4) JP7162059B2 (fr)
KR (1) KR20200100625A (fr)
CN (1) CN111491659A (fr)
AR (1) AR113983A1 (fr)
AU (2) AU2018392818C1 (fr)
BR (1) BR112020005186A2 (fr)
CA (1) CA3083069A1 (fr)
DK (1) DK3727429T3 (fr)
EA (1) EA202091527A1 (fr)
ES (1) ES3036736T3 (fr)
FI (1) FI3727429T3 (fr)
HU (1) HUE071806T2 (fr)
MA (1) MA51279A (fr)
MX (1) MX2020006043A (fr)
PL (1) PL3727429T3 (fr)
PT (1) PT3727429T (fr)
SG (1) SG11202002876WA (fr)
TW (1) TWI810228B (fr)
WO (1) WO2019122166A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202001353D0 (en) * 2020-01-31 2020-03-18 Ipsen Biopharm Ltd Treatment of skin conditions
TWI825396B (zh) * 2020-03-16 2023-12-11 英商艾普森生物製藥有限公司 肢體痙攣之治療
GB202206353D0 (en) * 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of cervical dystonia
JP2025534349A (ja) * 2022-09-30 2025-10-15 イプセン バイオファーム リミテッド 膀胱痛症候群の治療

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0328060D0 (en) 2003-12-04 2004-01-07 Sod Conseils Rech Applic Botulinum toxin treatment
DE102004043009A1 (de) 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen
DE102005019302A1 (de) 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
ATE518882T1 (de) 2005-09-19 2011-08-15 Allergan Inc Mit clostridientoxin aktivierbare clostridientoxine
UA116985C2 (uk) 2012-05-30 2018-06-11 Президент Енд Феллоуз Оф Гарвард Колледж Рекомбінантний ботулінічний нейротоксин
GB201312317D0 (en) * 2013-07-09 2013-08-21 Syntaxin Ltd Cationic neurotoxins
PT3274364T (pt) * 2015-03-26 2021-11-05 Harvard College Neurotoxina botulínica manipulada
GB201505306D0 (en) * 2015-03-27 2015-05-13 Ipsen Biopharm Ltd Chimeric polypeptides
TW201718627A (zh) * 2015-06-11 2017-06-01 梅茲製藥有限兩合公司 重組梭菌神經毒素及其使用與形成方法、包括其之醫藥組合物及對應其之前驅物、編碼前驅物之核酸序列及其獲得方法與前驅物之形成方法、載體與包括核酸序列之重組宿主細胞
GB201607901D0 (en) * 2016-05-05 2016-06-22 Ipsen Biopharm Ltd Chimeric neurotoxins
IL263058B2 (en) * 2016-06-08 2023-11-01 Childrens Medical Center Engineered botulinum neurotoxins
CN109106957A (zh) * 2018-11-08 2019-01-01 自贡德西玛医疗设备有限公司 一种旋转增效的高温消毒系统

Also Published As

Publication number Publication date
AU2018392818A1 (en) 2020-03-19
FI3727429T3 (fi) 2025-07-04
JP2021504301A (ja) 2021-02-15
WO2019122166A1 (fr) 2019-06-27
ES3036736T3 (en) 2025-09-23
BR112020005186A2 (pt) 2020-09-15
PT3727429T (pt) 2025-06-12
EP4591933A3 (fr) 2025-10-22
EP3727429B1 (fr) 2025-05-07
JP2022191409A (ja) 2022-12-27
JP7659676B2 (ja) 2025-04-09
TWI810228B (zh) 2023-08-01
JP7445725B2 (ja) 2024-03-07
JP2024059821A (ja) 2024-05-01
KR20200100625A (ko) 2020-08-26
US20250101397A1 (en) 2025-03-27
CN111491659A (zh) 2020-08-04
AU2025202320A1 (en) 2025-04-17
AU2018392818B2 (en) 2025-01-16
CA3083069A1 (fr) 2019-06-27
HUE071806T2 (hu) 2025-09-28
JP2025098207A (ja) 2025-07-01
SG11202002876WA (en) 2020-07-29
JP7162059B2 (ja) 2022-10-27
TW202017590A (zh) 2020-05-16
US20200377872A1 (en) 2020-12-03
MX2020006043A (es) 2020-08-17
EA202091527A1 (ru) 2020-09-11
EP3727429A1 (fr) 2020-10-28
DK3727429T3 (da) 2025-07-21
AR113983A1 (es) 2020-07-08
EP4591933A2 (fr) 2025-07-30
PL3727429T3 (pl) 2025-08-25
AU2018392818C1 (en) 2025-06-19

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