MA51790A - Échafaudages issus du génie tissulaire, bioréacteurs instrumentés et procédés d'utilisation associés - Google Patents

Échafaudages issus du génie tissulaire, bioréacteurs instrumentés et procédés d'utilisation associés

Info

Publication number
MA51790A
MA51790A MA051790A MA51790A MA51790A MA 51790 A MA51790 A MA 51790A MA 051790 A MA051790 A MA 051790A MA 51790 A MA51790 A MA 51790A MA 51790 A MA51790 A MA 51790A
Authority
MA
Morocco
Prior art keywords
tissue engineering
associated usage
usage procedures
instrumented
bioreactors
Prior art date
Application number
MA051790A
Other languages
English (en)
Inventor
Christophe Chantre
Josue A Goss
Luke A Macqueen
Kevin Kit Parker
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of MA51790A publication Critical patent/MA51790A/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14Scaffolds; Matrices
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/20Material Coatings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Clinical Laboratory Science (AREA)
  • Mechanical Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)
MA051790A 2018-02-08 2019-02-05 Échafaudages issus du génie tissulaire, bioréacteurs instrumentés et procédés d'utilisation associés MA51790A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862627799P 2018-02-08 2018-02-08

Publications (1)

Publication Number Publication Date
MA51790A true MA51790A (fr) 2020-12-16

Family

ID=67548543

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051790A MA51790A (fr) 2018-02-08 2019-02-05 Échafaudages issus du génie tissulaire, bioréacteurs instrumentés et procédés d'utilisation associés

Country Status (5)

Country Link
US (1) US20210371790A1 (fr)
EP (1) EP3749745A4 (fr)
CN (1) CN111918956A (fr)
MA (1) MA51790A (fr)
WO (1) WO2019156941A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3124904A1 (fr) 2019-01-14 2020-07-23 President And Fellows Of Harvard College Dispositifs rotatifs de filature a jet d'air cible et procedes d'utilisation associes
EP3933028A1 (fr) 2020-06-30 2022-01-05 Novoheart Limited Dispositifs comprenant des chambres d'organoïdes et leurs utilisations pour cultiver, maintenir, surveiller ou tester des organoïdes
US12527960B2 (en) * 2020-07-16 2026-01-20 Biosense Webster (Israel) Ltd. Apparatus for testing a cardiac catheter utilizing live cardiac cells
EP4689046A2 (fr) * 2023-04-06 2026-02-11 Valo Health, Inc. Systèmes et procédés concernant une exploration de pic et une réponse de tissu artificiel comprenant un suivi d'échafaudage tissulaire
WO2025240819A1 (fr) * 2024-05-16 2025-11-20 3D Systems, Inc. Procédés et systèmes pour réaliser un contrôle de qualité de réseaux de fluides de tissus biologiquement modifiés

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050209687A1 (en) * 2002-02-19 2005-09-22 Bioartis, Inc. Artificial vessel scaffold and artifical organs therefrom
US7348175B2 (en) * 2002-03-15 2008-03-25 St3 Development Corporation Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
JP2006311887A (ja) * 2005-05-06 2006-11-16 Imoto Seisakusho:Kk 生体管状器官培養方法及びその装置
CA2613945A1 (fr) * 2007-12-12 2009-06-12 The Hospital For Sick Children Bioreacteur a vessie
CN101824382B (zh) * 2010-03-25 2012-05-02 清华大学 灌注-灌流-脉动联合构建的组织工程心肌生物反应器
KR101104336B1 (ko) * 2010-05-03 2012-01-16 (주)마이크로디지탈 배양액 박동장치 및 박동식 배양 시스템
EP2468846A1 (fr) * 2010-12-22 2012-06-27 Ludwig-Maximilians-Universität München Procédé pour examiner la croissance tissulaire et le conditionnement de cellules sur un support et bioréacteur à perfusion
AU2014205510B2 (en) * 2013-01-08 2017-12-21 Raredon Resources, Inc. Human and large-mammal lung bioreactor
EP2986705B1 (fr) * 2013-04-18 2020-03-25 The Trustees of Columbia University in the City of New York Bioréacteur de perfusion à régulation du débit tissulaire et compatible avec l'imagerie en direct
CN103805511B (zh) * 2014-02-18 2015-10-28 国家纳米科学中心 可在高倍物镜下直接观测的动脉血管模拟微流控装置
CN105985925B (zh) * 2015-03-04 2019-08-09 刘畅 一种全功能人工器官拟合体及其制备和培养方法

Also Published As

Publication number Publication date
EP3749745A4 (fr) 2021-11-10
US20210371790A1 (en) 2021-12-02
WO2019156941A8 (fr) 2020-08-27
EP3749745A1 (fr) 2020-12-16
CN111918956A (zh) 2020-11-10
WO2019156941A9 (fr) 2019-12-26
WO2019156941A1 (fr) 2019-08-15

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