MA53015A - Anticorps anti-sirp-bêta1 et procédés d'utilisation associés - Google Patents

Anticorps anti-sirp-bêta1 et procédés d'utilisation associés

Info

Publication number
MA53015A
MA53015A MA053015A MA53015A MA53015A MA 53015 A MA53015 A MA 53015A MA 053015 A MA053015 A MA 053015A MA 53015 A MA53015 A MA 53015A MA 53015 A MA53015 A MA 53015A
Authority
MA
Morocco
Prior art keywords
sirp
associated procedures
beta1
antibodies
beta1 antibodies
Prior art date
Application number
MA053015A
Other languages
English (en)
Inventor
Patricia Culp
Andrew Pincetic
Arnon Rosenthal
Original Assignee
Alector Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alector Llc filed Critical Alector Llc
Publication of MA53015A publication Critical patent/MA53015A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA053015A 2018-06-29 2019-06-28 Anticorps anti-sirp-bêta1 et procédés d'utilisation associés MA53015A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862691913P 2018-06-29 2018-06-29

Publications (1)

Publication Number Publication Date
MA53015A true MA53015A (fr) 2021-05-05

Family

ID=67439371

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053015A MA53015A (fr) 2018-06-29 2019-06-28 Anticorps anti-sirp-bêta1 et procédés d'utilisation associés

Country Status (14)

Country Link
US (2) US12060422B2 (fr)
EP (1) EP3814377A2 (fr)
JP (2) JP7575278B2 (fr)
KR (1) KR20210025614A (fr)
CN (2) CN112384532B (fr)
AU (1) AU2019293589A1 (fr)
BR (1) BR112020026819A2 (fr)
CA (1) CA3099176A1 (fr)
EA (1) EA202190138A1 (fr)
IL (1) IL279648A (fr)
MA (1) MA53015A (fr)
MX (1) MX2020013324A (fr)
SG (1) SG11202010990TA (fr)
WO (1) WO2020006374A2 (fr)

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EA201890171A1 (ru) 2015-06-30 2018-08-31 Сэнфорд-Бернхем Медикал Рисерч Инститьют Слитые белки btla агонисты и их применение
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
KR20230005268A (ko) * 2020-04-24 2023-01-09 밀레니엄 파머슈티컬스 인코퍼레이티드 항-cd19 항체 및 이의 용도
CN116162157B (zh) * 2020-05-19 2025-07-01 益科思特(北京)医药科技发展有限公司 抗新型冠状病毒Spike蛋白抗体及其应用
EP4251280A4 (fr) * 2020-11-30 2024-11-06 Merck Sharp & Dohme LLC Liants d'arginase 1 pour inhiber l'activité de l'arginase 1
US20240101667A1 (en) * 2020-12-03 2024-03-28 The Board Of Regents Of The University Of Texas System Methods for identifying lilrb-blocking antibodies
CN114478802B (zh) * 2022-01-28 2023-05-26 郑州大学 一种嵌合抗原受体及其应用
CN120202222A (zh) 2022-11-16 2025-06-24 勃林格殷格翰国际有限公司 抗SIRPa抗体的疗效预测性生物标志物
WO2024187149A2 (fr) * 2023-03-09 2024-09-12 Triveni Bio, Inc. Anticorps de kallicréine à double inhibiteur et leurs utilisations
WO2025049347A1 (fr) * 2023-08-25 2025-03-06 Triveni Bio, Inc. Anticorps ciblant klk5/7 + il-4 et leurs utilisations
WO2025049348A1 (fr) * 2023-08-25 2025-03-06 Triveni Bio, Inc. Anticorps ciblant klk5/7 + il-13 et leurs utilisations
AU2024333809A1 (en) * 2023-08-25 2026-02-26 Triveni Bio, Inc. Klk5/7 + th2 targeting antibodies and uses thereof
WO2025101471A1 (fr) * 2023-11-09 2025-05-15 Merck Sharp & Dohme Llc Dosage de puissance biologique à base de cellules d'anticorps anti-cd27
WO2025166146A1 (fr) * 2024-02-02 2025-08-07 Triveni Bio, Inc. Anticorps ciblant klk5/7 + ox40 et leurs utilisations
WO2025166138A1 (fr) * 2024-02-02 2025-08-07 Triveni Bio, Inc. Anticorps ciblant klk5/7 + tslp et leurs utilisations

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Also Published As

Publication number Publication date
BR112020026819A2 (pt) 2021-04-20
JP2024119792A (ja) 2024-09-03
SG11202010990TA (en) 2020-12-30
AU2019293589A1 (en) 2021-01-21
IL279648A (en) 2021-03-01
JP2021529520A (ja) 2021-11-04
EA202190138A1 (ru) 2021-05-27
CA3099176A1 (fr) 2020-01-02
EP3814377A2 (fr) 2021-05-05
WO2020006374A2 (fr) 2020-01-02
KR20210025614A (ko) 2021-03-09
US20210277113A1 (en) 2021-09-09
CN112384532A (zh) 2021-02-19
CN112384532B (zh) 2025-01-10
CN119912569A (zh) 2025-05-02
US12060422B2 (en) 2024-08-13
US20250026827A1 (en) 2025-01-23
MX2020013324A (es) 2021-05-12
JP7575278B2 (ja) 2024-10-29
WO2020006374A3 (fr) 2020-02-20

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