MA52643A - Anticorps se liant spécifiquement au tl1a - Google Patents
Anticorps se liant spécifiquement au tl1aInfo
- Publication number
- MA52643A MA52643A MA052643A MA52643A MA52643A MA 52643 A MA52643 A MA 52643A MA 052643 A MA052643 A MA 052643A MA 52643 A MA52643 A MA 52643A MA 52643 A MA52643 A MA 52643A
- Authority
- MA
- Morocco
- Prior art keywords
- tl1a
- binding specifically
- antibodies binding
- antibodies
- specifically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Sorting Of Articles (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562220442P | 2015-09-18 | 2015-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA52643A true MA52643A (fr) | 2021-03-24 |
Family
ID=57043002
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA42825A MA42825B1 (fr) | 2015-09-18 | 2016-09-16 | Anticorps se liant spécifiquement à tl1a |
| MA052643A MA52643A (fr) | 2015-09-18 | 2016-09-16 | Anticorps se liant spécifiquement au tl1a |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA42825A MA42825B1 (fr) | 2015-09-18 | 2016-09-16 | Anticorps se liant spécifiquement à tl1a |
Country Status (33)
| Country | Link |
|---|---|
| US (4) | US10138296B2 (fr) |
| EP (2) | EP3350223B1 (fr) |
| JP (2) | JP7013366B2 (fr) |
| KR (1) | KR101998535B1 (fr) |
| CN (1) | CN108137693B (fr) |
| AR (1) | AR106055A1 (fr) |
| AU (2) | AU2016323460B2 (fr) |
| BR (1) | BR122021002400A8 (fr) |
| CA (1) | CA2997015A1 (fr) |
| CL (1) | CL2018000711A1 (fr) |
| CO (1) | CO2018003736A2 (fr) |
| CY (1) | CY1123499T1 (fr) |
| DK (1) | DK3350223T3 (fr) |
| EA (1) | EA201890756A1 (fr) |
| ES (1) | ES2810751T3 (fr) |
| HR (1) | HRP20201323T1 (fr) |
| HU (1) | HUE051496T2 (fr) |
| IL (1) | IL257761B2 (fr) |
| LT (1) | LT3350223T (fr) |
| MA (2) | MA42825B1 (fr) |
| MD (1) | MD3350223T2 (fr) |
| MX (1) | MX2018003185A (fr) |
| PE (1) | PE20181080A1 (fr) |
| PH (1) | PH12018500580B1 (fr) |
| PL (1) | PL3350223T3 (fr) |
| PT (1) | PT3350223T (fr) |
| RS (1) | RS60703B1 (fr) |
| SI (1) | SI3350223T1 (fr) |
| SM (1) | SMT202000500T1 (fr) |
| TW (1) | TWI703158B (fr) |
| UA (1) | UA125284C2 (fr) |
| WO (1) | WO2017049024A1 (fr) |
| ZA (1) | ZA201801427B (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| AU2012315474B2 (en) | 2011-09-30 | 2017-10-26 | Teva Pharmaceuticals Australia Pty Ltd. | Antibodies against TL1a and uses thereof |
| KR20240122922A (ko) | 2013-03-27 | 2024-08-13 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| EP4105236A1 (fr) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anticorps contre tl1a (tnfsf15) pour le traitement des maladies inflammatoires de l'intestin |
| TWI703158B (zh) | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| IL294038A (en) * | 2015-12-04 | 2022-08-01 | Univ Iowa Res Found | Device, systems and methods for prediction, screening and monitoring of encephalopathy / delirium |
| CR20180365A (es) | 2015-12-16 | 2018-09-28 | Amgen Inc | PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS |
| CN109462996A (zh) | 2016-03-17 | 2019-03-12 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
| CN110121509B (zh) | 2016-10-26 | 2024-05-07 | 西达-赛奈医疗中心 | 中和抗tl1a单克隆抗体 |
| KR20240046307A (ko) * | 2017-04-28 | 2024-04-08 | 아지노모토 가부시키가이샤 | 가용성 단백질에 대한 친화성 물질, 절단성 부분 및 반응성기를 갖는 화합물 또는 이의 염 |
| MA52366A (fr) | 2018-04-25 | 2021-03-03 | Prometheus Biosciences Inc | Anticorps anti-tl1a optimisés |
| WO2020232125A1 (fr) | 2019-05-14 | 2020-11-19 | Prometheus Biosciences, Inc. | Méthodes, systèmes et dispositifs de sélection de patient tl1a |
| PH12022550978A1 (en) | 2019-10-24 | 2023-10-09 | Cedars Sinai Medical Center | Humanized antibodies to tnf-like ligand 1a (tl1a) and uses thereof |
| KR20230051581A (ko) * | 2020-08-19 | 2023-04-18 | 얀센 바이오테크 인코포레이티드 | 조작된 리간드를 사용하는 물질 및 방법 |
| JP2024508762A (ja) * | 2021-02-18 | 2024-02-28 | プロメテウス バイオサイエンシーズ,インク. | 抗tl1a抗体組成物及び肺における治療方法 |
| AU2023314783A1 (en) | 2022-07-27 | 2025-03-06 | Cephalon Llc | Anti-tl1a antibodies for the treatment of ulcerative colitis and crohn's disease |
| CA3262152A1 (fr) | 2022-07-27 | 2024-02-01 | Cephalon Llc | Formulations d'anticorps anti-tl1a |
| WO2024239006A1 (fr) | 2023-05-17 | 2024-11-21 | Genentech, Inc. | Méthodesthérapeutiques à base d'anticorps anti-tl1a |
| WO2024263945A2 (fr) * | 2023-06-22 | 2024-12-26 | Paragon Therapeutics, Inc. | Compositions d'anticorps ciblant l'il-17 et procédés d'utilisation |
| AU2024312669A1 (en) * | 2023-06-22 | 2026-02-05 | Paragon Therapeutics, Inc. | Il-23 antibody compositions and methods of use |
| AU2024324300A1 (en) * | 2023-08-11 | 2026-02-12 | Paragon Therapeutics, Inc. | Tl1a binding antibodies and methods of use |
| WO2025076081A1 (fr) | 2023-10-03 | 2025-04-10 | Absci Corporation | Compositions d'anticorps associés à tl1a et procédés d'utilisation |
| CN120058933B (zh) * | 2023-11-30 | 2026-02-10 | 北京智仁美博生物科技有限公司 | 抗肿瘤坏死因子样配体1a的抗体及其用途 |
| US20250230251A1 (en) | 2023-12-20 | 2025-07-17 | Bristol-Myers Squibb Company | Antibodies targeting il-18 receptor beta (il-18rb) and related methods |
| CN120424214A (zh) * | 2024-02-05 | 2025-08-05 | 三生国健药业(上海)股份有限公司 | 一种抗tl1a抗体及其制备方法和用途 |
| TW202540171A (zh) | 2024-02-06 | 2025-10-16 | 美商派拉岡醫療公司 | Il-23抗體組合物及使用方法 |
| CN120590530A (zh) * | 2024-03-05 | 2025-09-05 | 帆礼生物技术(武汉)有限公司 | 靶向tl1a的抗体及其应用 |
| US20250376530A1 (en) | 2024-05-17 | 2025-12-11 | Genentech, Inc. | Methods for treatment of inflammatory bowel disease with an anti-tl1a antibody |
| CN119552252B (zh) * | 2025-01-16 | 2025-11-25 | 华润生物医药有限公司 | 抗tl1a抗体及其制备方法和应用 |
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| PT1355919E (pt) | 2000-12-12 | 2011-03-02 | Medimmune Llc | Moléculas com semivida longa, composições que as contêm e suas utilizações |
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| WO2012161856A1 (fr) | 2011-05-20 | 2012-11-29 | Government Of The United States, As Represented By The Secretary, Department Of Health And Human Services | Blocage des interactions tl1a-dr3 pour améliorer la pathologie des maladies médiées par les cellules t et anticorps afférents |
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| AU2012315474B2 (en) * | 2011-09-30 | 2017-10-26 | Teva Pharmaceuticals Australia Pty Ltd. | Antibodies against TL1a and uses thereof |
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| KR20240122922A (ko) | 2013-03-27 | 2024-08-13 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| WO2014165771A2 (fr) * | 2013-04-05 | 2014-10-09 | Genentech, Inc. | Anticorps anti-il-4 et anticorps bispécifiques et leurs utilisations |
| JP6482533B2 (ja) | 2013-05-17 | 2019-03-13 | セダーズ−シナイ メディカル センター | クローン病に関連するtnfsf15及びdcr3の変異体 |
| WO2014186665A2 (fr) | 2013-05-17 | 2014-11-20 | Cedars-Sinai Medical Center | Effets distincts d'ifn gamma et d'il-17 sur une inflammation et une fibrose modulées par tl1a |
| EP4105236A1 (fr) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anticorps contre tl1a (tnfsf15) pour le traitement des maladies inflammatoires de l'intestin |
| MX2016002879A (es) | 2013-09-06 | 2016-08-17 | Cedars Sinai Medical Center | Sistemas, dispositivos y metodos para la terapia anti-tl1a. |
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| TWI703158B (zh) | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| US20180319889A1 (en) | 2015-11-02 | 2018-11-08 | La Jolla Institute For Allergy & Immunology | Method and medicament for treating airway and/or lung diseases |
| CR20180365A (es) | 2015-12-16 | 2018-09-28 | Amgen Inc | PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS |
| CN109462996A (zh) | 2016-03-17 | 2019-03-12 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
| JP7012665B6 (ja) | 2016-05-09 | 2023-12-14 | ブリストル-マイヤーズ スクイブ カンパニー | Tl1a抗体およびその使用 |
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| WO2018195328A1 (fr) | 2017-04-20 | 2018-10-25 | Cedars-Sinai Medical Center | Procédés de prédiction de non-réponse à un traitement anti-tnf chez des sujets atteints d'une affection intestinale inflammatoire |
| MA52366A (fr) | 2018-04-25 | 2021-03-03 | Prometheus Biosciences Inc | Anticorps anti-tl1a optimisés |
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| WO2020232125A1 (fr) | 2019-05-14 | 2020-11-19 | Prometheus Biosciences, Inc. | Méthodes, systèmes et dispositifs de sélection de patient tl1a |
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| WO2021108694A1 (fr) | 2019-11-27 | 2021-06-03 | Cedars-Sinai Medical Center | Prédiction de manifestations extra-intestinales de maladies intestinales inflammatoires |
| EP4162067A4 (fr) | 2020-06-03 | 2024-07-10 | Cedars-Sinai Medical Center | Méthodes et systèmes de mesure de la récurrence d'une maladie après opération |
| EP4162076A4 (fr) | 2020-06-03 | 2024-10-02 | Cedars-Sinai Medical Center | Traitements pour une sous-population de patients atteints d'une maladie intestinale inflammatoire |
| MX2022016590A (es) | 2020-06-26 | 2023-02-01 | Pfizer | Metodos de tratamiento de la enfermedad inflamatoria intestinal con anticuerpos tl1a. |
| BR112023009172A2 (pt) | 2020-11-13 | 2023-10-03 | Cedars Sinai Medical Center | Métodos, sistemas e kits para tratamento de doenças inflamatórias direcionados à tl1a |
| WO2022119842A1 (fr) | 2020-12-01 | 2022-06-09 | Cedars-Sinai Medical Center | Procédés et systèmes pour stratification de patients atteints de maladie inflammatoire |
| EP4263585A4 (fr) | 2020-12-21 | 2024-11-27 | Cedars-Sinai Medical Center | Compositions thérapeutiques de tl1a et méthodes de traitement les utilisant |
| JP2024508762A (ja) | 2021-02-18 | 2024-02-28 | プロメテウス バイオサイエンシーズ,インク. | 抗tl1a抗体組成物及び肺における治療方法 |
| MX2023009622A (es) | 2021-02-18 | 2023-08-28 | Prometheus Biosciences Inc | Composiciones que comprenden anticuerpos humanizados contra ligandos de tipo tnf 1a (tl1a) y sus usos. |
| WO2022232253A1 (fr) | 2021-04-28 | 2022-11-03 | Cedars-Sinai Medical Center | Procédés et kits de sélection des patients pour thérapies ciblant tl1a |
| WO2023102051A1 (fr) | 2021-12-01 | 2023-06-08 | Cedars-Sinai Medical Center | Phagocytes mononucléaires intestinaux en tant que biomarqueur de pronostic pour la maladie de crohn |
| US20260000713A1 (en) | 2021-12-01 | 2026-01-01 | Cedars-Sinai Medical Center | Microbial metabolites on intestinal inflammation |
| CN118829653A (zh) | 2022-01-07 | 2024-10-22 | 普罗米修斯生物科学公司 | 用tl1a抑制剂和il23抑制剂的组合治疗炎性疾病的方法 |
| US20240059799A1 (en) | 2022-05-11 | 2024-02-22 | Pfizer Inc. | Anti-tl1a antibodies and methods of use thereof |
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