MA42380A - Anticorps se liant à tau - Google Patents

Anticorps se liant à tau

Info

Publication number
MA42380A
MA42380A MA042380A MA42380A MA42380A MA 42380 A MA42380 A MA 42380A MA 042380 A MA042380 A MA 042380A MA 42380 A MA42380 A MA 42380A MA 42380 A MA42380 A MA 42380A
Authority
MA
Morocco
Prior art keywords
tau
antibodies
bonding
antibodies bonding
Prior art date
Application number
MA042380A
Other languages
English (en)
Inventor
Terence Seward Baker
Jean-Philippe Courade
Patrick Downey
David Edward Ormonde Knight
Coello Georges Mairet-
Kerry Louise Tyson
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of MA42380A publication Critical patent/MA42380A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
MA042380A 2015-07-06 2016-07-05 Anticorps se liant à tau MA42380A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15175519 2015-07-06

Publications (1)

Publication Number Publication Date
MA42380A true MA42380A (fr) 2018-05-16

Family

ID=53524638

Family Applications (2)

Application Number Title Priority Date Filing Date
MA042380A MA42380A (fr) 2015-07-06 2016-07-05 Anticorps se liant à tau
MA41669A MA41669A1 (fr) 2015-07-06 2016-07-05 Anticorps se liant a tau

Family Applications After (1)

Application Number Title Priority Date Filing Date
MA41669A MA41669A1 (fr) 2015-07-06 2016-07-05 Anticorps se liant a tau

Country Status (23)

Country Link
US (4) US10344081B2 (fr)
EP (1) EP3319984B1 (fr)
JP (1) JP6937289B2 (fr)
KR (1) KR102742965B1 (fr)
CN (1) CN107849105B (fr)
AR (1) AR105266A1 (fr)
AU (1) AU2016289753C1 (fr)
CA (1) CA2991264C (fr)
CL (1) CL2018000042A1 (fr)
CO (1) CO2017012974A2 (fr)
EA (1) EA036821B1 (fr)
EC (1) ECSP18000844A (fr)
ES (1) ES3064846T3 (fr)
IL (1) IL256687B (fr)
MA (2) MA42380A (fr)
MX (1) MX2017015908A (fr)
PE (1) PE20180499A1 (fr)
PH (1) PH12017502180A1 (fr)
TN (1) TN2017000543A1 (fr)
TW (1) TWI748954B (fr)
UY (1) UY36774A (fr)
WO (1) WO2017005732A1 (fr)
ZA (1) ZA201708128B (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10501531B2 (en) 2013-03-13 2019-12-10 Prothena Biosciences Limited Tau immunotherapy
NZ775762A (en) 2015-06-05 2025-02-28 Genentech Inc Anti-tau antibodies and methods of use
US10344081B2 (en) 2015-07-06 2019-07-09 Ucb Biopharma Sprl Tau-binding antibodies
WO2017005734A1 (fr) 2015-07-06 2017-01-12 Ucb Biopharma Sprl Anticorps se liant à tau
MY198194A (en) 2016-05-02 2023-08-09 Prothena Biosciences Ltd Antibodies Recognizing Tau
PT3452507T (pt) 2016-05-02 2022-12-20 Prothena Biosciences Ltd Imunoterapia anti-tau
UA128383C2 (uk) 2016-12-07 2024-07-03 Дженентек, Інк. Антитіло до тау-білка та спосіб його застосування
MX2019006330A (es) 2016-12-07 2019-09-26 Genentech Inc Anticuerpos anti-tau y metodos de uso.
WO2018119142A1 (fr) 2016-12-21 2018-06-28 Amgen Inc. Formulations d'anticorps anti-tnf alpha
WO2018148447A1 (fr) * 2017-02-08 2018-08-16 Adimab, Llc Domaines variables de chaînes lourdes d'anticorps ciblant le récepteur nkg2d
AU2018219887B2 (en) 2017-02-08 2024-08-15 Dragonfly Therapeutics, LLC Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
SG11201907422RA (en) 2017-02-17 2019-09-27 Denali Therapeutics Inc Anti-tau antibodies and methods of use thereof
CN110944661A (zh) 2017-02-20 2020-03-31 蜻蜓疗法股份有限公司 结合her2、nkg2d和cd16的蛋白质
JP2018139530A (ja) 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
KR102784294B1 (ko) 2017-05-02 2025-03-19 프로테나 바이오사이언시즈 리미티드 타우 인식 항체
AU2018352308B2 (en) 2017-10-16 2025-06-05 Eisai R&D Management Co., Ltd. Anti-tau antibodies and uses thereof
CA3237846A1 (fr) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Domaines variables d'anticorps ciblant le recepteur nkg2d
BR112020015994A2 (pt) 2018-02-08 2020-12-15 Dragonfly Therapeutics, Inc. Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer
WO2019164930A1 (fr) 2018-02-20 2019-08-29 Dragonfly Therapeutics, Inc. Protéines de liaison multi-spécifiques qui se lient à cd33, nkg2d et cd16, et procédés d'utilisation
KR102835308B1 (ko) 2018-08-08 2025-07-21 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
EP3833392A4 (fr) 2018-08-08 2022-05-18 Dragonfly Therapeutics, Inc. Protéines de liaison multi-spécifiques se liant à bcma, nkg2d et cd16, et méthodes d'utilisation
EP3894438A1 (fr) * 2018-12-13 2021-10-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Nouvel anticorps à domaine unique d'épitope dirigé contre tau svqivykpv
JP7630834B2 (ja) 2019-03-03 2025-02-18 プロセナ バイオサイエンシーズ リミテッド タウ認識抗体
US20230151083A1 (en) * 2020-04-08 2023-05-18 Janssen Biotech, Inc. Anti-phf-tau antibodies and uses thereof
JP7512394B2 (ja) 2020-05-06 2024-07-08 ドラゴンフライ セラピューティクス， インコーポレイテッド Ｎｋｇ２ｄ、ｃｄ１６及びｃｌｅｃ１２ａに結合するタンパク質
CA3183835A1 (fr) 2020-06-25 2021-12-30 Jeanne E. Baker Anticorps a haute affinite ciblant la proteine tau phosphorylee a la position 413 de serine
WO2022144406A1 (fr) * 2020-12-29 2022-07-07 Neurimmune Ag Anticorps anti-tau humains
EP4301774A4 (fr) 2021-03-03 2025-08-13 Dragonfly Therapeutics Inc Méthodes de traitement du cancer à l'aide de protéines de liaison multi-spécifiques qui se lient à nkg2d, à cd16 et à un antigène associé à une tumeur
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders
KR20250069606A (ko) 2022-09-15 2025-05-19 보이저 테라퓨틱스, 인크. 타우 결합 화합물
WO2025122634A1 (fr) 2023-12-05 2025-06-12 Voyager Therapeutics, Inc. Compositions et méthodes pour le traitement de troubles liés à la protéine tau
WO2025147472A1 (fr) * 2024-01-02 2025-07-10 Phanes Therapeutics, Inc. Anticorps anti-611-ctf p95her2 et leurs utilisations
WO2025196217A1 (fr) 2024-03-21 2025-09-25 UCB Biopharma SRL Traitement de tauopathies avec des anticorps se liant à la protéine tau
WO2026057816A1 (fr) 2024-09-13 2026-03-19 UCB Biopharma SRL Traitement de tauopathies avec des anticorps se liant à la protéine tau

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
EP0519596B1 (fr) 1991-05-17 2005-02-23 Merck & Co. Inc. Procédé pour réduire l'immunogénicité des domaines variables d'anticorps
GB9112536D0 (en) 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds
DE69220503T2 (de) 1991-10-25 1998-02-05 Innogenetics Nv Monoklonale Antikörper gegen das mikrotubulusassoziierte Protein Tau.
US7408027B1 (en) 1991-12-06 2008-08-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften Tools for the diagnosis and treatment of Alzheimer's disease
US6010913A (en) 1992-12-14 2000-01-04 N.V. Innogenetics S.A. Isolated human tau peptide
ES2270421T3 (es) 1993-12-21 2007-04-01 Innogenetics N.V. Anticuerpos monoclonales especificos para phf-tau, hibridomas que secretan los mismos, reconocimiento de antigeno por estos anticuerpos y sus aplicaciones.
WO1996004309A1 (fr) 1994-07-29 1996-02-15 Innogenetics N.V. Anticorps monoclonaux specifiques d'un epitope d'une sous-classe ou forme particuliere de tau phosphorylee, hybridomes les secretant, reconnaissance par les antigenes de ces anticorps et leurs applications
ES2551439T5 (es) 2003-07-01 2018-11-08 Ucb Biopharma Sprl Fragmentos Fab de anticuerpos modificados
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
GB0411186D0 (en) 2004-05-19 2004-06-23 Celltech R&D Ltd Biological products
CN1721437A (zh) * 2004-07-13 2006-01-18 中南大学 一种与Tau蛋白相关的多肽抗原及抗体
NZ612578A (en) 2005-08-19 2014-11-28 Abbvie Inc Dual variable domain immunoglobin and uses thereof
EP1959996A2 (fr) 2005-12-12 2008-08-27 AC Immune S.A. Anticorps monoclonal
GB0614780D0 (en) 2006-07-25 2006-09-06 Ucb Sa Biological products
GB0624500D0 (en) * 2006-12-07 2007-01-17 Istituto Superiore Di Sanito A novel passive vaccine for candida infections
EP2535349A1 (fr) 2007-09-26 2012-12-19 UCB Pharma S.A. Fusions d'anticorps à double spécificité
KR101581244B1 (ko) * 2008-03-26 2015-12-31 에피토믹스, 인코포레이티드 항―ｖｅｇｆ 항체
CN101307108B (zh) * 2008-06-25 2012-04-04 南京川博生物技术有限公司 抗磷酸化Tau蛋白抗体及其在AD症异常磷酸化Tau蛋白水平测定上的用途
CA2737241C (fr) 2008-09-26 2017-08-29 Ucb Pharma S.A. Proteines de fusion d'anticorps multivalentes
UA107571C2 (xx) 2009-04-03 2015-01-26 Фармацевтична композиція
CN106390107B (zh) 2009-06-10 2019-12-31 纽约大学 病理tau蛋白的免疫靶向
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
JP2013500326A (ja) 2009-07-30 2013-01-07 ファイザー バクシーンズ エルエルシー 抗原性タウペプチドおよびその使用
WO2011030107A1 (fr) 2009-09-10 2011-03-17 Ucb Pharma S.A. Anticorps multivalents
CA2813493C (fr) 2010-10-11 2019-07-09 University Of Zurich Anticorps anti-tau humain
US20120244174A1 (en) 2011-01-31 2012-09-27 Intellect Neurosciences Inc. Treatment of tauopathies
GB201112056D0 (en) 2011-07-14 2011-08-31 Univ Leuven Kath Antibodies
ME03008B (fr) 2011-09-19 2018-10-20 Axon Neuroscience Se Thérapie protéique et diagnostic d'une pathologie à médiation par tau dans la maladie d'alzheimer
KR101981351B1 (ko) * 2011-10-07 2019-09-02 에이씨 이뮨 에스.에이. 타우를 인식하는 포스포특이적 항체
WO2013068571A1 (fr) 2011-11-11 2013-05-16 Ucb Pharma S.A. Anticorps se liant à l'albumine et leurs fragments de liaison
MX350311B (es) 2011-12-20 2017-09-01 Janssen Biotech Inc Anticuerpos anti-phf-tau y sus usos.
RU2644242C2 (ru) 2012-04-05 2018-02-08 Ац Иммуне С.А. Гуманизированное тау-антитело
SG10201708959WA (en) 2012-07-03 2017-11-29 Univ Washington Antibodies to tau
WO2014016737A1 (fr) 2012-07-24 2014-01-30 Pfizer Inc. Nouveaux anticorps monoclonaux de poulet dirigés contre la protéine tau phosphorylée humaine et leurs utilisations
NZ630542A (en) 2012-08-16 2017-06-30 Ipierian Inc Methods of treating a tauopathy
CA2896066C (fr) 2012-12-21 2022-07-12 Biogen Ma Inc. Anticorps anti-tau humains
US10501531B2 (en) 2013-03-13 2019-12-10 Prothena Biosciences Limited Tau immunotherapy
WO2014150877A2 (fr) 2013-03-15 2014-09-25 Ac Immune S.A. Anticorps anti-tau et leurs procédés d'utilisation
AU2014368696A1 (en) 2013-12-20 2016-06-02 F. Hoffmann-La Roche Ag Humanized anti-Tau(pS422) antibodies and methods of use
CA2874083C (fr) * 2014-12-05 2024-01-02 Universite Laval Polypeptides liant le tdp-43 utiles pour le traitement de maladies neurodegeneratives
TWI669314B (zh) 2015-02-26 2019-08-21 美國禮來大藥廠 針對ｔａｕ之抗體及其用途
NZ775762A (en) 2015-06-05 2025-02-28 Genentech Inc Anti-tau antibodies and methods of use
US10344081B2 (en) 2015-07-06 2019-07-09 Ucb Biopharma Sprl Tau-binding antibodies
WO2017005734A1 (fr) 2015-07-06 2017-01-12 Ucb Biopharma Sprl Anticorps se liant à tau
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها

Also Published As

Publication number Publication date
JP2018519833A (ja) 2018-07-26
TWI748954B (zh) 2021-12-11
NZ737843A (en) 2024-05-31
IL256687B (en) 2022-02-01
CA2991264A1 (fr) 2017-01-12
EP3319984C0 (fr) 2026-03-11
US10344081B2 (en) 2019-07-09
MX2017015908A (es) 2018-03-15
US20190375829A1 (en) 2019-12-12
TW201713688A (zh) 2017-04-16
CL2018000042A1 (es) 2018-06-01
AR105266A1 (es) 2017-09-20
AU2016289753A1 (en) 2017-12-14
EP3319984A1 (fr) 2018-05-16
PE20180499A1 (es) 2018-03-09
AU2016289753B2 (en) 2020-11-26
EP3319984B1 (fr) 2026-03-11
WO2017005732A1 (fr) 2017-01-12
ZA201708128B (en) 2019-05-29
US20210139574A1 (en) 2021-05-13
KR20180027566A (ko) 2018-03-14
JP6937289B2 (ja) 2021-09-22
US10906966B2 (en) 2021-02-02
IL256687A (en) 2018-03-29
ES3064846T3 (en) 2026-04-29
US11746145B2 (en) 2023-09-05
CN107849105B (zh) 2021-09-17
PH12017502180A1 (en) 2018-05-28
BR112017028101A2 (en) 2018-09-04
ECSP18000844A (es) 2018-03-31
US20230331833A1 (en) 2023-10-19
UY36774A (es) 2017-01-31
AU2016289753C1 (en) 2021-08-05
MA41669A1 (fr) 2018-05-31
EA036821B1 (ru) 2020-12-23
TN2017000543A1 (en) 2019-04-12
KR102742965B1 (ko) 2024-12-13
US20180194832A1 (en) 2018-07-12
CA2991264C (fr) 2023-10-10
EA201890169A1 (ru) 2018-10-31
CO2017012974A2 (es) 2018-03-09
CN107849105A (zh) 2018-03-27

Similar Documents

Publication Publication Date Title
MA42380A (fr) Anticorps se liant à tau
MA42377A (fr) Anticorps se liant à tau
FR24C1056I2 (fr) Nouveaux anticorps anti-pd-l1
MA51734A (fr) Anticorps se liant à gprc5d
FR25C1022I2 (fr) Anticorps anti-pd-1
EP3512549A4 (fr) Anticorps se liant à cd3
EP3498840A4 (fr) Anticorps anti-lag-3
EP3423089A4 (fr) Anticorps anti-tigit
EP3334757A4 (fr) Anticorps anti-tigit
MA42626A (fr) Nouveaux anticorps anti-pd-1
EP3297671A4 (fr) Anticorps anti-ror1
EP3334824A4 (fr) Anticorps anti-pd-1
MA45004A (fr) Anticorps spécifiques anti-wt1-hla
EP3349787A4 (fr) Anticorps cd47 thérapeutiques
EP3307777A4 (fr) Nouveaux anticorps anti-pd-l1
MA52643A (fr) Anticorps se liant spécifiquement au tl1a
MA53297A (fr) Anticorps anti-icos
EP3507307A4 (fr) Anticorps bispécifiques
EP3492591A4 (fr) Anticorps anti-b7-h4
MA49289A (fr) Anticorps se liant à steap-1
EP3383915A4 (fr) Anticorps anti-pd-1
EP3526247A4 (fr) Anticorps anti-il1-rap
IL263272A (en) Anti-coagulation factor xi antibodies
EP3484919A4 (fr) Anticorps anti-bêta-amyloïde
EP3399992A4 (fr) Anticorps autoréticulants