MA52762A - Lipides cationiques comprenant une fraction stéroïdienne - Google Patents
Lipides cationiques comprenant une fraction stéroïdienneInfo
- Publication number
- MA52762A MA52762A MA052762A MA52762A MA52762A MA 52762 A MA52762 A MA 52762A MA 052762 A MA052762 A MA 052762A MA 52762 A MA52762 A MA 52762A MA 52762 A MA52762 A MA 52762A
- Authority
- MA
- Morocco
- Prior art keywords
- fat containing
- cationic fat
- steroid fraction
- steroid
- fraction
- Prior art date
Links
- 150000003431 steroids Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/52—Isomerases (5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6018—Lipids, e.g. in lipopeptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862677821P | 2018-05-30 | 2018-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA52762A true MA52762A (fr) | 2021-04-14 |
Family
ID=67003655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA052762A MA52762A (fr) | 2018-05-30 | 2019-05-30 | Lipides cationiques comprenant une fraction stéroïdienne |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11547666B2 (fr) |
| EP (2) | EP4442831A3 (fr) |
| JP (2) | JP7463006B2 (fr) |
| CN (1) | CN112424214A (fr) |
| AU (1) | AU2019278813B2 (fr) |
| CA (1) | CA3100214A1 (fr) |
| ES (1) | ES2989886T3 (fr) |
| MA (1) | MA52762A (fr) |
| WO (1) | WO2019232208A1 (fr) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8853377B2 (en) * | 2010-11-30 | 2014-10-07 | Shire Human Genetic Therapies, Inc. | mRNA for use in treatment of human genetic diseases |
| EP3793689A1 (fr) * | 2018-05-15 | 2021-03-24 | Translate Bio, Inc. | Administration sous-cutanée d'arn messager |
| CN118436618A (zh) | 2018-05-30 | 2024-08-06 | 川斯勒佰尔公司 | 信使rna疫苗及其用途 |
| EP3986452A1 (fr) | 2019-06-18 | 2022-04-27 | CureVac AG | Vaccin à arnm rotavirus |
| CA3146369A1 (fr) | 2019-07-08 | 2021-01-14 | Translate Bio, Inc. | Nanoparticules lipidiques chargees d'arn messager ameliorees et leurs procedes de fabrication |
| US12194089B2 (en) | 2020-02-04 | 2025-01-14 | CureVac SE | Coronavirus vaccine |
| DE202021004130U1 (de) | 2020-02-04 | 2022-10-26 | Curevac Ag | Coronavirus-Vakzine |
| WO2021239880A1 (fr) | 2020-05-29 | 2021-12-02 | Curevac Ag | Vaccins combinés à base d'acide nucléique |
| EP4172194A1 (fr) | 2020-07-31 | 2023-05-03 | CureVac SE | Mélanges d'anticorps codés par des acides nucléiques |
| WO2022043551A2 (fr) | 2020-08-31 | 2022-03-03 | Curevac Ag | Vaccins contre le coronavirus à base d'acides nucléiques multivalents |
| MX2023004371A (es) | 2020-10-14 | 2023-07-26 | George Mason Res Foundation Inc | Lípidos ionizables, y métodos de fabricación y uso de los mismos. |
| MX2023007574A (es) | 2020-12-22 | 2023-09-29 | CureVac SE | "vacuna de arn contra variantes de sars-cov-2. |
| US20240299309A1 (en) | 2020-12-22 | 2024-09-12 | CureVac SE | Pharmaceutical composition comprising lipid-based carriers encapsulating rna for multidose administration |
| CA3170747A1 (fr) | 2021-01-27 | 2022-08-04 | Moritz THRAN | Procede de reduction des proprietes immunostimulatrices d'arn transcrit in vitro |
| EP4312988A2 (fr) | 2021-03-31 | 2024-02-07 | CureVac SE | Seringues contenant des compositions pharmaceutiques comprenant de l'arn |
| CA3215606A1 (fr) * | 2021-04-19 | 2022-10-27 | Shrirang KARVE | Compositions ameliorees pour l'administration d'arnm |
| CA3171589A1 (fr) | 2021-05-03 | 2022-11-03 | Moritz THRAN | Sequence d'acide nucleique amelioree pour l'expression specifique de type cellulaire |
| EP4763287A2 (fr) | 2021-09-03 | 2026-06-24 | CureVac SE | Nouvelles nanoparticules lipidiques pour l'administration d'acides nucléiques |
| EP4422698A1 (fr) | 2021-10-29 | 2024-09-04 | CureVac SE | Arn circulaire amélioré pour exprimer des protéines thérapeutiques |
| EP4469091A1 (fr) | 2022-01-28 | 2024-12-04 | CureVac SE | Inhibiteurs de facteurs de transcription codés par un acide nucleique |
| CN117003807B (zh) * | 2022-04-28 | 2026-05-26 | 北京科兴中维生物技术有限公司 | 一种结构脂质化合物及其制备方法和用途 |
| CN117003808B (zh) * | 2022-04-28 | 2026-05-29 | 北京科兴中维生物技术有限公司 | 一种阳离子脂质化合物及其制备方法和用途 |
| CA3248209A1 (fr) | 2022-05-25 | 2023-11-30 | CureVac SE | Vaccin à base d’acide nucléique codant pour un polypeptide antigénique fimh d’escherichia coli |
| WO2024012270A1 (fr) * | 2022-07-11 | 2024-01-18 | 传信生物医药(苏州)有限公司 | Composition pour l'administration spécifique à un organe d'acide nucléique |
| WO2024089638A1 (fr) | 2022-10-28 | 2024-05-02 | Glaxosmithkline Biologicals Sa | Vaccin à base d'acide nucléique |
| WO2024140893A1 (fr) * | 2022-12-29 | 2024-07-04 | 辽宁键凯科技有限公司 | Composé lipidique cationique stéroïde et son utilisation |
| CN120641396A (zh) * | 2023-01-29 | 2025-09-12 | 正基基因科技有限公司 | 阳离子脂质与脂质纳米颗粒 |
| KR20250153298A (ko) | 2023-03-08 | 2025-10-24 | 큐어백 에스이 | 핵산 전달을 위한 신규의 지질 나노입자 제형 |
| EP4721759A1 (fr) | 2023-04-29 | 2026-04-08 | Cansino (Shanghai) Biological Research Co., Ltd. | Nanoparticule lipidique pour administrer un médicament à base d'acide nucléique, son procédé de préparation et son utilisation |
| WO2024227430A1 (fr) | 2023-04-29 | 2024-11-07 | 康希诺(上海)生物研发有限公司 | Composé lipidique cationique stéroïdien et son utilisation |
| WO2024230934A1 (fr) | 2023-05-11 | 2024-11-14 | CureVac SE | Acide nucléique thérapeutique pour le traitement de maladies ophtalmiques |
| CN117069785B (zh) * | 2023-07-04 | 2026-08-11 | 中生复诺健生物科技(上海)有限公司 | 脂质化合物和脂质纳米颗粒组合物 |
| WO2025113662A1 (fr) * | 2023-12-01 | 2025-06-05 | 康希诺(上海)生物研发有限公司 | Nanoparticule lipidique pour l'administration d'acide nucléique, son procédé de préparation et son utilisation |
| WO2026003582A2 (fr) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipides et nanoparticules lipidiques |
| WO2026036296A1 (fr) * | 2024-08-14 | 2026-02-19 | 康希诺(上海)生物研发有限公司 | Nanoparticules lipidiques pour l'administration de médicament à base d'acide nucléique, son procédé de préparation et son utilisation |
| WO2026061417A1 (fr) * | 2024-09-18 | 2026-03-26 | 北京茵诺医药科技有限公司 | Dérivé de stérol ionisable pour l'administration d'un agent thérapeutique et son utilisation |
| WO2026102567A1 (fr) * | 2024-11-12 | 2026-05-21 | National University Of Singapore | Nanoparticules lipidiques et méthodes correspondantes |
| CN120971717B (zh) * | 2025-10-21 | 2026-02-06 | 上海交通大学医学院附属仁济医院 | Serpinb10蛋白在制备嗜酸细胞性食管炎与反流性食管炎的鉴别诊断产品中的应用 |
Family Cites Families (50)
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| US4192871A (en) * | 1976-01-06 | 1980-03-11 | Glaxo Laboratories Limited | Chemical compounds |
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US5132418A (en) | 1980-02-29 | 1992-07-21 | University Patents, Inc. | Process for preparing polynucleotides |
| US4500707A (en) | 1980-02-29 | 1985-02-19 | University Patents, Inc. | Nucleosides useful in the preparation of polynucleotides |
| US4973679A (en) | 1981-03-27 | 1990-11-27 | University Patents, Inc. | Process for oligonucleo tide synthesis using phosphormidite intermediates |
| US4668777A (en) | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
| US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| US4373071A (en) | 1981-04-30 | 1983-02-08 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
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| US4897355A (en) | 1985-01-07 | 1990-01-30 | Syntex (U.S.A.) Inc. | N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
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| US5885613A (en) | 1994-09-30 | 1999-03-23 | The University Of British Columbia | Bilayer stabilizing components and their use in forming programmable fusogenic liposomes |
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| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| IT1304501B1 (it) * | 1998-12-23 | 2001-03-19 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza |
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| DE60325329D1 (de) * | 2002-01-18 | 2009-01-29 | Univ Minnesota | Quaternäre terpensalze als biologisch aktive tenside |
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| WO2010053572A2 (fr) | 2008-11-07 | 2010-05-14 | Massachusetts Institute Of Technology | Lipidoïdes aminoalcool et leurs utilisations |
| KR20220038506A (ko) | 2009-06-10 | 2022-03-28 | 알닐람 파마슈티칼스 인코포레이티드 | 향상된 지질 조성물 |
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| US9512073B2 (en) | 2011-10-27 | 2016-12-06 | Massachusetts Institute Of Technology | Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof |
| BR112014024131A2 (pt) | 2012-03-29 | 2017-07-25 | Shire Human Genetic Therapies | lipídios catiônicos ionizáveis |
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| US10059655B2 (en) | 2013-12-19 | 2018-08-28 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| WO2015184256A2 (fr) | 2014-05-30 | 2015-12-03 | Shire Human Genetic Therapies, Inc. | Lipides biodégradables pour l'administration d'acides nucléiques |
| CA2953341C (fr) | 2014-06-25 | 2023-01-24 | Acuitas Therapeutics Inc. | Lipides et formulations de nanoparticules de lipides pour l'administration d'acides nucleiques |
| WO2016004202A1 (fr) | 2014-07-02 | 2016-01-07 | Massachusetts Institute Of Technology | Lipidoïdes dérivés de polyamine-acide gras et leurs utilisations |
| WO2016079685A1 (fr) * | 2014-11-20 | 2016-05-26 | Taplast S.P.A. | Élément élastique pour dispositif pour la distribution de fluides ou de mélanges et procédé et moule pour la fabrication dudit élément élastique |
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| HUE067372T2 (hu) | 2015-06-29 | 2024-10-28 | Acuitas Therapeutics Inc | Lipidek és nanoszemcsés lipid formulázások nukleinsavak beadására |
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| US12678515B2 (en) | 2015-12-30 | 2026-07-14 | Acuitas Therapeutics, Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| ES3030658T3 (en) | 2016-03-30 | 2025-07-01 | Intellia Therapeutics Inc | Lipid nanoparticle formulations for crispr/cas components |
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| US20170325457A1 (en) * | 2016-04-28 | 2017-11-16 | Preceres Inc. | Formulations for the delivery of active agents to insects, plants, and plant pathogens |
| US20180153822A1 (en) | 2016-11-10 | 2018-06-07 | Translate Bio, Inc. | Process of Preparing mRNA-Loaded Lipid Nanoparticles |
| JP7256824B2 (ja) | 2018-04-25 | 2023-04-12 | エスリス ゲーエムベーハー | 粒子状製剤用の凍結保護剤 |
-
2019
- 2019-05-30 MA MA052762A patent/MA52762A/fr unknown
- 2019-05-30 EP EP24182407.7A patent/EP4442831A3/fr not_active Withdrawn
- 2019-05-30 WO PCT/US2019/034651 patent/WO2019232208A1/fr not_active Ceased
- 2019-05-30 EP EP19733242.2A patent/EP3802558B1/fr active Active
- 2019-05-30 ES ES19733242T patent/ES2989886T3/es active Active
- 2019-05-30 US US17/058,334 patent/US11547666B2/en active Active
- 2019-05-30 CN CN201980046445.4A patent/CN112424214A/zh active Pending
- 2019-05-30 JP JP2020566730A patent/JP7463006B2/ja active Active
- 2019-05-30 AU AU2019278813A patent/AU2019278813B2/en active Active
- 2019-05-30 CA CA3100214A patent/CA3100214A1/fr active Pending
-
2024
- 2024-01-31 JP JP2024012730A patent/JP2024032912A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021525744A (ja) | 2021-09-27 |
| US20210220273A1 (en) | 2021-07-22 |
| JP7463006B2 (ja) | 2024-04-08 |
| CN112424214A (zh) | 2021-02-26 |
| US11547666B2 (en) | 2023-01-10 |
| AU2019278813B2 (en) | 2023-12-07 |
| JP2024032912A (ja) | 2024-03-12 |
| EP3802558B1 (fr) | 2024-09-11 |
| CA3100214A1 (fr) | 2019-12-05 |
| EP4442831A3 (fr) | 2024-10-30 |
| ES2989886T3 (es) | 2024-11-28 |
| EP4442831A2 (fr) | 2024-10-09 |
| AU2019278813A1 (en) | 2020-12-03 |
| EP3802558C0 (fr) | 2024-09-11 |
| WO2019232208A1 (fr) | 2019-12-05 |
| EP3802558A1 (fr) | 2021-04-14 |
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