MA52861A - Méthodes et compositions pour le traitement de l'apnée du sommeil - Google Patents

Méthodes et compositions pour le traitement de l'apnée du sommeil

Info

Publication number
MA52861A
MA52861A MA052861A MA52861A MA52861A MA 52861 A MA52861 A MA 52861A MA 052861 A MA052861 A MA 052861A MA 52861 A MA52861 A MA 52861A MA 52861 A MA52861 A MA 52861A
Authority
MA
Morocco
Prior art keywords
compositions
treatment
methods
sleep apnea
apnea
Prior art date
Application number
MA052861A
Other languages
English (en)
Other versions
MA52861B1 (fr
Inventor
Walter J Lunsmann
Lawrence G Miller
Barry Wohl
Original Assignee
Apnimed Inc Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apnimed Inc Delaware filed Critical Apnimed Inc Delaware
Publication of MA52861A publication Critical patent/MA52861A/fr
Publication of MA52861B1 publication Critical patent/MA52861B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MA52861A 2018-01-30 2019-01-30 Méthodes et compositions pour le traitement de l'apnée du sommeil ou le ronflement simple MA52861B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862623892P 2018-01-30 2018-01-30
EP19705634.4A EP3746126B1 (fr) 2018-01-30 2019-01-30 Méthodes et compositions pour le traitement de l'apnée du sommeil ou le ronflement simple
PCT/US2019/015781 WO2019152475A1 (fr) 2018-01-30 2019-01-30 Méthodes et compositions pour le traitement de l'apnée du sommeil

Publications (2)

Publication Number Publication Date
MA52861A true MA52861A (fr) 2021-05-05
MA52861B1 MA52861B1 (fr) 2024-09-30

Family

ID=65441079

Family Applications (1)

Application Number Title Priority Date Filing Date
MA52861A MA52861B1 (fr) 2018-01-30 2019-01-30 Méthodes et compositions pour le traitement de l'apnée du sommeil ou le ronflement simple

Country Status (27)

Country Link
US (6) US11911351B2 (fr)
EP (2) EP3746126B1 (fr)
JP (3) JP7422666B2 (fr)
KR (2) KR20250156197A (fr)
CN (2) CN118384147A (fr)
AU (2) AU2019214891B2 (fr)
BR (1) BR112020015316A2 (fr)
CA (1) CA3089712A1 (fr)
DK (1) DK3746126T3 (fr)
EA (1) EA202091597A1 (fr)
ES (1) ES2991425T3 (fr)
FI (1) FI3746126T3 (fr)
HR (1) HRP20241412T1 (fr)
HU (1) HUE068505T2 (fr)
IL (1) IL276247A (fr)
LT (1) LT3746126T (fr)
MA (1) MA52861B1 (fr)
MD (1) MD3746126T2 (fr)
MX (2) MX2020008086A (fr)
PL (1) PL3746126T3 (fr)
PT (1) PT3746126T (fr)
RS (1) RS66104B1 (fr)
SG (1) SG11202007226UA (fr)
SI (1) SI3746126T1 (fr)
SM (1) SMT202400400T1 (fr)
UA (1) UA129618C2 (fr)
WO (1) WO2019152475A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GEAP202416602A (en) 2017-04-28 2024-10-10 Brigham & Womens Hospital Inc Methods and compositions for treating sleep apnea
EA202192202A1 (ru) 2019-02-08 2021-11-03 Дзе Брихэм Энд Уимен'З Хоспитал, Инк. Способы и композиции для лечения синдрома обструктивного апноэ, возникающего во сне
US20220362221A1 (en) * 2019-11-04 2022-11-17 Apnimed, Inc. (Delaware) Combination pharmacological interventions for multiple mechanisms of obstructive sleep apnea
CN116391233A (zh) * 2020-09-30 2023-07-04 皇家飞利浦有限公司 用于执行剂量滴定的方法和系统
CA3210092A1 (fr) * 2021-03-04 2022-09-09 Lawrence G. Miller Combinaison de reboxetine et d'un antagoniste du recepteur muscarinique (arm) destinee a etre utilisee dans le traitement de l'apnee du sommeil
KR20230159462A (ko) * 2021-03-24 2023-11-21 애프니메드, 인코포레이티드 (델라웨어) 수면 무호흡증 치료 방법 및 조성물
EP4334281A1 (fr) 2021-05-04 2024-03-13 Apnimed, Inc. (Delaware) Formes solides de (r)-oxybutynine d-malate
IL309251A (en) * 2021-06-17 2024-02-01 Apnimed Inc Delaware Norepinephrine reuptake inhibitors for the treatment of sleep apnea
CA3259602A1 (fr) 2021-12-22 2023-06-29 Bayer Aktiengesellschaft Combinaison d’un antagoniste alpha 2-adrénocepteur de sous-type c (alpha-2 c) et d’un antagoniste du récepteur muscarinique pour le traitement de l’apnée du sommeil
KR20240124995A (ko) 2021-12-22 2024-08-19 바이엘 악티엔게젤샤프트 수면 무호흡의 치료를 위한 a2-아드레날린수용체 하위유형 c (알파-2c) 길항제와 노르에피네프린 재흡수 억제제의 조합물
US20250302814A1 (en) * 2022-05-13 2025-10-02 Apnimed, Inc. (Delaware) Methods and compositions for treating sleep apnea
KR20250000641A (ko) * 2023-06-27 2025-01-03 주식회사 아스트로젠 수면장애 및/또는 수면장애 관련 질환을 예방, 개선 또는 치료하는 방법

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JPH11515015A (ja) 1995-10-24 1999-12-21 グルーエネンタール ゲゼルシャフト ミット ベシュレンクテル ハフツング 睡眠無呼吸の抑止方法
CN1660435A (zh) * 2000-02-24 2005-08-31 法玛西雅厄普约翰美国公司 新的药物联合形式
US20020155113A1 (en) 2001-03-13 2002-10-24 Miyoung Chun Methods for treating or preventing cardiovascular disorders by modulating metalloprotease function
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US20030185882A1 (en) * 2001-11-06 2003-10-02 Vergez Juan A. Pharmaceutical compositions containing oxybutynin
US20040235925A1 (en) 2002-12-17 2004-11-25 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
CA2523567A1 (fr) 2003-04-25 2004-11-11 Indevus Pharmaceuticals, Inc. Procede destine a favoriser un sommeil ininterrompu par l'administration d'un chlorure de trospium
WO2005063254A2 (fr) 2003-12-22 2005-07-14 Acadia Pharmaceuticals Inc. Analogues de diaryl[a,d]cycloheptene amino substitues utilises comme agonistes muscariniques, et procedes de traitement de troubles neuropsychiatriques
US20060039866A1 (en) 2004-08-20 2006-02-23 Cypress Bioscience, Inc. Method for treating sleep-related breathing disorders
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
EP1827450A4 (fr) 2004-11-17 2009-04-22 Cypress Bioscience Inc Methodes servant a limiter les effets secondaires d'un traitement par mirtazapine
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CA2603920A1 (fr) 2005-04-15 2006-10-26 The Board Of Trustees Of The University Of Illinois Traitement pharmacologique pour le traitement des apnees du sommeil
US20070021921A1 (en) 2005-07-21 2007-01-25 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Selective resonance of chemical structures
FR2889811B1 (fr) 2005-08-19 2009-10-09 Sanofi Aventis Sa Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique.
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AR065989A1 (es) 2007-04-09 2009-07-15 Sepracor Inc Metodos y composiciones para el tratamiento de trastornos de la respiracion relacionados con el sueno
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EP2672972B1 (fr) 2011-01-28 2020-11-04 Pfantastic Medical Research Institute, LLC Procédés pour traiter l'apnée obstructive du sommeil
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ES2925951T3 (es) 2015-07-22 2022-10-20 John Hsu Composición que comprende un agente terapéutico y un estimulante respiratorio y métodos para su uso
WO2017031319A1 (fr) 2015-08-18 2017-02-23 Massachusetts Institute Of Technology Traitement par médicament noradrénergique de l'apnée obstructive du sommeil
GEAP202416602A (en) * 2017-04-28 2024-10-10 Brigham & Womens Hospital Inc Methods and compositions for treating sleep apnea
AU2019216257B2 (en) 2018-01-31 2025-11-20 Research Institute At Nationwide Children's Hospital Gene therapy for limb-girdle muscular dystrophy type 2C
EA202192202A1 (ru) 2019-02-08 2021-11-03 Дзе Брихэм Энд Уимен'З Хоспитал, Инк. Способы и композиции для лечения синдрома обструктивного апноэ, возникающего во сне

Also Published As

Publication number Publication date
MA52861B1 (fr) 2024-09-30
JP2025159230A (ja) 2025-10-17
EP4445951A3 (fr) 2025-01-08
JP7422666B2 (ja) 2024-01-26
EP3746126B1 (fr) 2024-07-31
EA202091597A1 (ru) 2020-10-22
ES2991425T3 (es) 2024-12-03
AU2019214891A1 (en) 2020-08-20
CN111670050A (zh) 2020-09-15
SG11202007226UA (en) 2020-08-28
PT3746126T (pt) 2024-10-21
CA3089712A1 (fr) 2019-08-08
HRP20241412T1 (hr) 2024-12-20
PL3746126T3 (pl) 2024-12-16
AU2019214891B2 (en) 2024-08-01
JP2021516218A (ja) 2021-07-01
UA129618C2 (uk) 2025-06-18
LT3746126T (lt) 2024-10-25
RS66104B1 (sr) 2024-11-29
US11911351B2 (en) 2024-02-27
US20220378724A1 (en) 2022-12-01
US20210038541A1 (en) 2021-02-11
BR112020015316A2 (pt) 2020-12-08
MX2024001713A (es) 2024-02-20
NZ766673A (en) 2025-08-29
KR20200115598A (ko) 2020-10-07
AU2024227631A1 (en) 2024-11-14
MX2020008086A (es) 2021-02-15
HUE068505T2 (hu) 2024-12-28
DK3746126T3 (da) 2024-10-07
KR102874891B1 (ko) 2025-10-21
SMT202400400T1 (it) 2024-11-15
EP3746126A1 (fr) 2020-12-09
FI3746126T3 (fi) 2024-10-10
EP4445951A2 (fr) 2024-10-16
US20260027070A1 (en) 2026-01-29
IL276247A (en) 2020-09-30
US20240156753A1 (en) 2024-05-16
SI3746126T1 (sl) 2025-01-31
WO2019152475A1 (fr) 2019-08-08
KR20250156197A (ko) 2025-10-31
US20250186371A1 (en) 2025-06-12
CN118384147A (zh) 2024-07-26
US20240390299A1 (en) 2024-11-28
MD3746126T2 (ro) 2024-12-31
JP2023181322A (ja) 2023-12-21

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