MA52935A - Composés inhibiteurs d'oga - Google Patents

Composés inhibiteurs d'oga

Info

Publication number: MA52935A
Authority: MA; Morocco
Prior art keywords: inhibitor compounds; oga inhibitor; oga; compounds; inhibitor
Prior art date: 2018-06-20

Application number

MA052935A

Other languages

English (en)

Inventor

José Manuel Bartolomé-Nebreda

Susana Conde-Ceide

Francisca Delgado-Jiménez

Carlos Manuel Martinez-Viturro

Andrés Avelino Trabanco-Suárez

Ramiro Juan Antonio Vega

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2018-06-20

Filing date

2019-06-20

Publication date

2021-04-28

2019-06-20 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2021-04-28 Publication of MA52935A publication Critical patent/MA52935A/fr

Links

229940126137 O-GlcNAcase inhibitor Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Hospice & Palliative Care (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Psychiatry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MA052935A 2018-06-20 2019-06-20 Composés inhibiteurs d'oga MA52935A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP18382447		2018-06-20

Publications (1)

Publication Number	Publication Date
MA52935A true MA52935A (fr)	2021-04-28

Family

ID=62784074

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
MA052934A MA52934A (fr)	2018-06-20	2019-06-20	Composés inhibiteurs de l'oga
MA052935A MA52935A (fr)	2018-06-20	2019-06-20	Composés inhibiteurs d'oga

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
MA052934A MA52934A (fr)	2018-06-20	2019-06-20	Composés inhibiteurs de l'oga

Country Status (9)

Country	Link
US (2)	US20210300943A1 (fr)
EP (2)	EP3810594A1 (fr)
JP (2)	JP2021528413A (fr)
CN (2)	CN112292377A (fr)
AU (2)	AU2019289968A1 (fr)
CA (2)	CA3102458A1 (fr)
MA (2)	MA52934A (fr)
TW (2)	TW202016093A (fr)
WO (2)	WO2019243526A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA3045745A1 (fr) *	2017-02-27	2018-08-30	Janssen Pharmaceutica Nv	Derives de [1,2,4]-triazolo [1,5-a]-pyrimidinyle substitues par de la piperidine, de la morpholine ou de la piperazine utilises en tant qu'inhibiteurs d'oga
WO2021094312A1 (fr) *	2019-11-11	2021-05-20	Janssen Pharmaceutica Nv	Composés inhibiteurs d'oga contenant de la pyrrolidine et de la bicyclohétéroaryle
US20250214980A1 (en)	2022-03-14	2025-07-03	Slap Pharmaceuticals Llc	Multicyclic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN107108601B (zh) *	2014-08-28	2021-08-20	阿森纽荣股份公司	糖苷酶抑制剂
KR20190020343A (ko) *	2016-06-29	2019-02-28	오리온 코포레이션	벤조디옥산 유도체 및 이의 약제학적 용도
JP2020503298A (ja) *	2016-12-16	2020-01-30	ヤンセンファーマシューティカエヌ．ベー．	単環式ｏｇａ阻害剤化合物

2019
- 2019-06-20 CA CA3102458A patent/CA3102458A1/fr not_active Abandoned
- 2019-06-20 WO PCT/EP2019/066384 patent/WO2019243526A1/fr not_active Ceased
- 2019-06-20 EP EP19732987.3A patent/EP3810594A1/fr not_active Withdrawn
- 2019-06-20 CN CN201980041379.1A patent/CN112292377A/zh active Pending
- 2019-06-20 US US17/253,432 patent/US20210300943A1/en not_active Abandoned
- 2019-06-20 EP EP19732986.5A patent/EP3810593A1/fr not_active Withdrawn
- 2019-06-20 JP JP2020570683A patent/JP2021528413A/ja active Pending
- 2019-06-20 CN CN201980041108.6A patent/CN112334461A/zh active Pending
- 2019-06-20 TW TW108121536A patent/TW202016093A/zh unknown
- 2019-06-20 AU AU2019289968A patent/AU2019289968A1/en not_active Abandoned
- 2019-06-20 TW TW108121537A patent/TW202012392A/zh unknown
- 2019-06-20 MA MA052934A patent/MA52934A/fr unknown
- 2019-06-20 MA MA052935A patent/MA52935A/fr unknown
- 2019-06-20 CA CA3102462A patent/CA3102462A1/fr not_active Abandoned
- 2019-06-20 US US17/253,414 patent/US20210277015A1/en not_active Abandoned
- 2019-06-20 AU AU2019289967A patent/AU2019289967A1/en not_active Abandoned
- 2019-06-20 JP JP2020570519A patent/JP2021527659A/ja active Pending
- 2019-06-20 WO PCT/EP2019/066385 patent/WO2019243527A1/fr not_active Ceased

Also Published As

Publication number	Publication date
CN112334461A (zh)	2021-02-05
CA3102458A1 (fr)	2019-12-26
EP3810594A1 (fr)	2021-04-28
MA52934A (fr)	2021-04-28
WO2019243526A1 (fr)	2019-12-26
TW202012392A (zh)	2020-04-01
AU2019289968A1 (en)	2020-12-17
TW202016093A (zh)	2020-05-01
EP3810593A1 (fr)	2021-04-28
CA3102462A1 (fr)	2019-12-26
CN112292377A (zh)	2021-01-29
WO2019243527A1 (fr)	2019-12-26
US20210277015A1 (en)	2021-09-09
JP2021528413A (ja)	2021-10-21
JP2021527659A (ja)	2021-10-14
AU2019289967A1 (en)	2020-12-17
US20210300943A1 (en)	2021-09-30

Publication	Publication Date	Title
MA52939A (fr)	2021-04-28	Composés inhibiteurs d'oga
MA52942A (fr)	2021-04-28	Composés inhibiteurs d'oga
MA47420A (fr)	2019-12-11	Composés inhibiteurs d'oga
IL292753A (en)	2022-07-01	Compounds
MA47575A (fr)	2020-01-01	Composés inhibiteurs d'oga monocyclique
EP3836923A4 (fr)	2022-05-18	Composés pyrrolo-dipyridine
MA47576A (fr)	2020-01-01	Composés inhibiteurs d'oga bicyclique
EP3941898C0 (fr)	2023-06-07	Composés fongicides
MA52948A (fr)	2021-04-28	Composés
EP3737672A4 (fr)	2021-09-15	Composés benzamide
IL286833A (en)	2021-10-31	Compositions containing brazzein
MA51669A (fr)	2021-03-31	Composés
EP3906029A4 (fr)	2022-09-21	Inhibiteurs de l'interaction ménine-mll
DK4083038T3 (da)	2024-12-09	Pyridazinylthiazolcarboxamidforbindelse
EP3464275A4 (fr)	2019-10-30	Composés inhibiteurs de l'egfr
MA53003A (fr)	2021-05-05	Composés
MA52004A (fr)	2021-01-20	Inhibiteurs d'o-glycoprotéine-2-acétamido-2-désoxy-3-d-glycopyranosidase
MA49006A (fr)	2020-02-05	Inhibiteurs d'ip6k
MA54521A (fr)	2022-03-30	Dérivés d'oxopyridine substitués
EP4077318A4 (fr)	2023-11-22	Composés
MA52946A (fr)	2021-04-28	Composés
EP3833342A4 (fr)	2022-07-13	Composés d'imidazotétrazine
EP3808747A4 (fr)	2022-03-09	Composé d'imidazopyridinone
MA53648A (fr)	2021-07-28	Inhibiteurs d'o-glycoprotéine-2-acétamido-2-désoxy-3-d-glucopyranosidase
EP4003986A4 (fr)	2023-03-01	Composés inhibiteurs