MA52946A - Composés - Google Patents

Composés

Info

Publication number
MA52946A
MA52946A MA052946A MA52946A MA52946A MA 52946 A MA52946 A MA 52946A MA 052946 A MA052946 A MA 052946A MA 52946 A MA52946 A MA 52946A MA 52946 A MA52946 A MA 52946A
Authority
MA
Morocco
Prior art keywords
compounds
Prior art date
Application number
MA052946A
Other languages
English (en)
Other versions
MA52946B1 (fr
Inventor
Steven Boakes
Pamela Brown
Scott Coleman
Michael Dawson
Esther Duperchy
Roy Lester
Dean Rivers
Mona Simonovic
Original Assignee
Spero Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spero Therapeutics Inc filed Critical Spero Therapeutics Inc
Publication of MA52946A publication Critical patent/MA52946A/fr
Publication of MA52946B1 publication Critical patent/MA52946B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA52946A 2018-06-25 2019-06-25 Composés MA52946B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862689602P 2018-06-25 2018-06-25
PCT/EP2019/066819 WO2020002325A1 (fr) 2018-06-25 2019-06-25 Composés

Publications (2)

Publication Number Publication Date
MA52946A true MA52946A (fr) 2021-04-28
MA52946B1 MA52946B1 (fr) 2024-03-29

Family

ID=67107423

Family Applications (1)

Application Number Title Priority Date Filing Date
MA52946A MA52946B1 (fr) 2018-06-25 2019-06-25 Composés

Country Status (31)

Country Link
US (3) US11459357B2 (fr)
EP (2) EP3810633B1 (fr)
JP (2) JP7488774B2 (fr)
KR (1) KR20210054500A (fr)
CN (2) CN112789287B (fr)
AR (1) AR116663A1 (fr)
AU (2) AU2019294261B2 (fr)
BR (1) BR112020026663A2 (fr)
CA (1) CA3103158A1 (fr)
CO (1) CO2020016080A2 (fr)
DK (1) DK3810633T3 (fr)
EA (1) EA202092819A1 (fr)
ES (1) ES2971732T3 (fr)
FI (1) FI3810633T3 (fr)
HR (1) HRP20240028T1 (fr)
HU (1) HUE065134T2 (fr)
IL (2) IL279620B2 (fr)
LT (1) LT3810633T (fr)
MA (1) MA52946B1 (fr)
MD (1) MD3810633T2 (fr)
MX (1) MX2020013811A (fr)
PH (1) PH12020552240A1 (fr)
PL (1) PL3810633T3 (fr)
PT (1) PT3810633T (fr)
RS (1) RS65128B1 (fr)
SG (1) SG11202012747VA (fr)
SI (1) SI3810633T1 (fr)
TW (2) TW202446783A (fr)
UA (1) UA128162C2 (fr)
WO (1) WO2020002325A1 (fr)
ZA (1) ZA202301937B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107108699A (zh) 2014-11-26 2017-08-29 新药物许可控股有限公司 化合物
MD3810633T2 (ro) * 2018-06-25 2024-05-31 Spero Therapeutics Inc Compuşi
TW202233649A (zh) 2020-11-06 2022-09-01 美商斯佩羅治療學股份有限公司 化合物
WO2022262823A1 (fr) * 2021-06-18 2022-12-22 华南理工大学 Composé promédicament de polymyxine sensible aux radicaux libres d'oxygène actif et son utilisation
CN120574287A (zh) * 2025-06-10 2025-09-02 中国药科大学 一种抗菌肽、组合物及应用
CN120518715B (zh) * 2025-07-24 2025-10-03 中国药科大学 一种抗菌肽、药物组合物及应用
CN120699105B (zh) * 2025-08-19 2025-11-21 中国药科大学 一种氘代抗菌肽及其组合物和应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2128617A (en) 1982-10-06 1984-05-02 Martti Vaara Polypeptides for use in antibacterial therapy
WO1988000950A2 (fr) 1986-08-06 1988-02-11 Fauchere Jean Luc Fabrication de conjugues a liaisons de covalence a partir d'un antibiotique et d'un derive non toxique de la polymyxine b
US20010021697A1 (en) 1987-09-14 2001-09-13 Henning Lowenstein Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components
TW274552B (fr) 1992-05-26 1996-04-21 Hoechst Ag
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
AU2004277977B2 (en) 2003-09-30 2010-10-28 Biomechanisms Inc. Compositions and methods for treating burns
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
US7807637B2 (en) 2006-08-11 2010-10-05 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
HUE028271T2 (en) 2006-08-11 2016-12-28 Northern Antibiotics Oy Polymixin derivatives and their applications
FI20085469A0 (fi) 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
US8193148B2 (en) 2008-02-08 2012-06-05 Northern Antibiotics Ltd. Short fatty acid tail polymyxin derivatives and uses thereof
US8329645B2 (en) 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
ES2334547B1 (es) 2008-09-10 2010-12-03 Universidad De Barcelona Compuestos peptidicos antibacterianos.
TW201035111A (en) 2008-12-23 2010-10-01 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
CN101851270A (zh) 2009-04-03 2010-10-06 梁浩 一种多粘菌素衍生物及其制备方法
WO2010130007A1 (fr) 2009-05-14 2010-11-18 Monash University Composés antimicrobiens
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012051663A1 (fr) 2010-10-21 2012-04-26 Monash University Composés antimicrobiens
WO2012168820A1 (fr) * 2011-06-08 2012-12-13 Pfizer Inc. Dérivés de polymyxine utiles en tant qu'agents antibactériens
BR112014012016A2 (pt) 2011-11-18 2017-05-16 Cantab Anti-Infectives Ltd compostos
JP6643758B2 (ja) 2013-05-22 2020-02-12 スペロ・セラピューティクス・インコーポレーテッド 異なった抗生物質と一緒の組合せ療法におけるポリミキシン誘導体及びその使用
RU2740190C2 (ru) 2014-03-11 2021-01-12 Сперо Терапьютикс, Инк. Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками
US10047126B2 (en) 2014-04-01 2018-08-14 Monash University Polymyxin derivatives as antimicrobial compounds
CN107108699A (zh) 2014-11-26 2017-08-29 新药物许可控股有限公司 化合物
KR20170098821A (ko) * 2014-12-17 2017-08-30 에프. 호프만-라 로슈 아게 소르타아제를 사용한 １ 단계로의 이중 폴리펩티드 컨쥬게이션을 위한 효소 원-포트 반응
WO2016166103A1 (fr) * 2015-04-13 2016-10-20 Xellia Pharmaceuticals Aps Dérivés de polymyxine
EP3356387B1 (fr) * 2015-09-29 2024-06-26 Monash University Composés antimicrobiens dérivés de polymyxine
AU2017285424B2 (en) * 2016-06-16 2022-08-18 International Aids Vaccine Initiative, Inc. Tuberculosis compositions and methods of treating or preventing tuberculosis
MD3810633T2 (ro) * 2018-06-25 2024-05-31 Spero Therapeutics Inc Compuşi
WO2020014501A1 (fr) 2018-07-11 2020-01-16 Cidara Therapeutics, Inc. Compositions et procédés pour le traitement d'infections bactériennes

Also Published As

Publication number Publication date
EP3810633A1 (fr) 2021-04-28
AR116663A1 (es) 2021-06-02
LT3810633T (lt) 2024-01-10
CN112789287B (zh) 2024-06-21
IL279620B2 (en) 2026-03-01
UA128162C2 (uk) 2024-04-24
WO2020002325A1 (fr) 2020-01-02
AU2024203362A1 (en) 2024-06-06
SG11202012747VA (en) 2021-01-28
CN118878638A (zh) 2024-11-01
HUE065134T2 (hu) 2024-05-28
MX2020013811A (es) 2021-03-09
HRP20240028T1 (hr) 2024-03-29
EP3810633B1 (fr) 2023-12-13
US20260103491A1 (en) 2026-04-16
DK3810633T3 (da) 2024-01-15
IL279620B1 (en) 2025-11-01
IL279620A (en) 2021-03-01
TW202446783A (zh) 2024-12-01
FI3810633T3 (fi) 2024-02-09
CA3103158A1 (fr) 2020-01-02
JP2021528449A (ja) 2021-10-21
MA52946B1 (fr) 2024-03-29
AU2019294261B2 (en) 2024-02-29
AU2019294261A1 (en) 2021-02-04
IL323560A (en) 2025-11-01
ES2971732T3 (es) 2024-06-06
NZ771833A (en) 2024-09-27
ZA202301937B (en) 2023-09-27
RS65128B1 (sr) 2024-02-29
PT3810633T (pt) 2024-02-19
CN112789287A (zh) 2021-05-11
US11459357B2 (en) 2022-10-04
US20210246169A1 (en) 2021-08-12
US12528837B2 (en) 2026-01-20
TW202019949A (zh) 2020-06-01
PL3810633T3 (pl) 2024-04-08
EP4316504A3 (fr) 2024-04-17
CO2020016080A2 (es) 2021-01-18
PH12020552240A1 (en) 2021-08-16
SI3810633T1 (sl) 2024-04-30
JP7488774B2 (ja) 2024-05-22
EA202092819A1 (ru) 2021-05-21
EP4316504A2 (fr) 2024-02-07
JP2024109664A (ja) 2024-08-14
KR20210054500A (ko) 2021-05-13
TWI851584B (zh) 2024-08-11
BR112020026663A2 (pt) 2021-03-23
MD3810633T2 (ro) 2024-05-31
US20230012121A1 (en) 2023-01-12

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