MA53547A - Composés de 2,6-diamino pyridine - Google Patents

Composés de 2,6-diamino pyridine

Info

Publication number
MA53547A
MA53547A MA053547A MA53547A MA53547A MA 53547 A MA53547 A MA 53547A MA 053547 A MA053547 A MA 053547A MA 53547 A MA53547 A MA 53547A MA 53547 A MA53547 A MA 53547A
Authority
MA
Morocco
Prior art keywords
pyridine compounds
diamino pyridine
diamino
compounds
pyridine
Prior art date
Application number
MA053547A
Other languages
English (en)
Inventor
Timothy Barrett Durham
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA53547A publication Critical patent/MA53547A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA053547A 2018-09-04 2019-08-29 Composés de 2,6-diamino pyridine MA53547A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862726520P 2018-09-04 2018-09-04

Publications (1)

Publication Number Publication Date
MA53547A true MA53547A (fr) 2022-04-27

Family

ID=67982138

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053547A MA53547A (fr) 2018-09-04 2019-08-29 Composés de 2,6-diamino pyridine

Country Status (28)

Country Link
US (1) US10781212B2 (fr)
EP (1) EP3846809B1 (fr)
JP (1) JP6813720B1 (fr)
KR (1) KR102365535B1 (fr)
CN (1) CN112601525B (fr)
AR (1) AR117640A1 (fr)
AU (1) AU2019334877B2 (fr)
BR (1) BR112021001881A2 (fr)
CA (1) CA3111725C (fr)
CL (1) CL2021000528A1 (fr)
CO (1) CO2021002768A2 (fr)
CR (1) CR20210085A (fr)
DO (1) DOP2021000027A (fr)
EA (1) EA202190302A1 (fr)
EC (1) ECSP21015267A (fr)
ES (1) ES2971802T3 (fr)
IL (1) IL280598B2 (fr)
JO (1) JOP20210039B1 (fr)
MA (1) MA53547A (fr)
MX (1) MX2021002472A (fr)
MY (1) MY200531A (fr)
PE (1) PE20211595A1 (fr)
PH (1) PH12021550449A1 (fr)
SG (1) SG11202101687TA (fr)
TW (1) TWI714231B (fr)
UA (1) UA124917C2 (fr)
WO (1) WO2020051058A1 (fr)
ZA (1) ZA202100700B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161621B2 (en) 2018-07-16 2024-12-10 The Regents Of The University Of Colorado Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease
TWI750685B (zh) * 2019-06-17 2021-12-21 美商美國禮來大藥廠 二取代吡唑化合物
WO2021129737A1 (fr) 2019-12-24 2021-07-01 南京明德新药研发有限公司 Composé à effet inhibiteur de khk
CN111423420A (zh) * 2020-04-30 2020-07-17 广州博济医药生物技术股份有限公司 作为己酮糖激酶抑制剂的并环化合物
EP4269404A4 (fr) * 2020-12-25 2024-12-04 Xizang Haisco Pharmaceutical Co., Ltd. Inhibiteur de cétohexokinase et son utilisation
ES3061522T3 (en) 2021-03-29 2026-04-06 Gilead Sciences Inc Khk inhibitors
EP4469435A1 (fr) * 2022-01-26 2024-12-04 Eli Lilly and Company Composés pyrrolidine
US20250145619A1 (en) * 2022-02-09 2025-05-08 Youngene Therapeutics Co., Ltd Khk inhibitor, preparation method therefor and use thereof
CN120344506A (zh) * 2022-12-08 2025-07-18 勃林格殷格翰国际有限公司 新型氰基吡啶khk抑制剂化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101088239B1 (ko) * 2006-09-20 2011-11-30 일라이 릴리 앤드 캄파니 Ｃｒｆ１ 수용체 길항제로서의 티아졸 피라졸로피리미딘
AR099937A1 (es) * 2014-04-04 2016-08-31 Sanofi Sa Compuestos de isoindolinona como moduladores de gpr119 para el tratamiento de diabetes, obesidad, dislipidemia y trastornos relacionados
CN106459013B (zh) * 2014-05-15 2019-10-25 阵列生物制药公司 作为trka激酶抑制剂的化合物及其用途
TN2018000198A1 (en) * 2015-12-29 2019-10-04 Pfizer Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors

Also Published As

Publication number Publication date
DOP2021000027A (es) 2021-03-15
BR112021001881A2 (pt) 2021-04-27
ZA202100700B (en) 2022-09-28
AU2019334877B2 (en) 2022-07-28
EP3846809B1 (fr) 2023-12-13
EP3846809A1 (fr) 2021-07-14
AU2019334877A1 (en) 2021-03-11
CO2021002768A2 (es) 2021-05-20
CR20210085A (es) 2021-04-29
EA202190302A1 (ru) 2021-06-10
JOP20210039A1 (ar) 2021-03-04
JP6813720B1 (ja) 2021-01-13
NZ774406A (en) 2024-09-27
IL280598A (en) 2021-03-25
CN112601525B (zh) 2023-11-10
CL2021000528A1 (es) 2021-07-30
KR20210034082A (ko) 2021-03-29
US10781212B2 (en) 2020-09-22
MX2021002472A (es) 2021-04-29
WO2020051058A1 (fr) 2020-03-12
ES2971802T3 (es) 2024-06-07
IL280598B2 (en) 2024-02-01
TWI714231B (zh) 2020-12-21
CA3111725A1 (fr) 2020-03-12
CA3111725C (fr) 2022-12-13
AR117640A1 (es) 2021-08-18
US20200071331A1 (en) 2020-03-05
PH12021550449A1 (en) 2021-09-27
SG11202101687TA (en) 2021-03-30
KR102365535B1 (ko) 2022-02-23
ECSP21015267A (es) 2021-04-29
PE20211595A1 (es) 2021-08-18
JP2021506949A (ja) 2021-02-22
CN112601525A (zh) 2021-04-02
TW202026289A (zh) 2020-07-16
UA124917C2 (uk) 2021-12-08
JOP20210039B1 (ar) 2024-04-18
IL280598B1 (en) 2023-10-01
MY200531A (en) 2023-12-31

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