MA55089A - Traitements combinés et stratification des patients avec des anticorps bispécifiques anti-egfr/c-met - Google Patents

Traitements combinés et stratification des patients avec des anticorps bispécifiques anti-egfr/c-met

Info

Publication number
MA55089A
MA55089A MA055089A MA55089A MA55089A MA 55089 A MA55089 A MA 55089A MA 055089 A MA055089 A MA 055089A MA 55089 A MA55089 A MA 55089A MA 55089 A MA55089 A MA 55089A
Authority
MA
Morocco
Prior art keywords
egfr
bispecific antibodies
combination treatments
patient stratification
met bispecific
Prior art date
Application number
MA055089A
Other languages
English (en)
Inventor
Sheri Moores
Smruthi Vijayaraghavan
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA55089A publication Critical patent/MA55089A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA055089A 2019-02-26 2020-02-24 Traitements combinés et stratification des patients avec des anticorps bispécifiques anti-egfr/c-met MA55089A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962810716P 2019-02-26 2019-02-26
US201962930190P 2019-11-04 2019-11-04

Publications (1)

Publication Number Publication Date
MA55089A true MA55089A (fr) 2022-01-05

Family

ID=72142314

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055089A MA55089A (fr) 2019-02-26 2020-02-24 Traitements combinés et stratification des patients avec des anticorps bispécifiques anti-egfr/c-met

Country Status (16)

Country Link
US (3) US11459391B2 (fr)
EP (1) EP3931224A4 (fr)
JP (3) JP7703448B2 (fr)
KR (1) KR20210132117A (fr)
CN (1) CN113840842A (fr)
AU (1) AU2020229467A1 (fr)
BR (1) BR112021016149A2 (fr)
CA (1) CA3131654A1 (fr)
IL (1) IL285718A (fr)
JO (1) JOP20210233A1 (fr)
MA (1) MA55089A (fr)
MX (1) MX2021010265A (fr)
NZ (1) NZ778579A (fr)
PH (1) PH12021552030A1 (fr)
SG (1) SG11202108311RA (fr)
WO (1) WO2020174370A2 (fr)

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MX2021010265A (es) 2019-02-26 2021-09-23 Janssen Biotech Inc Terapias de combinacion y estratificacion de pacientes con anticuerpos anti-egfr/c-met biespecificos.
US12629375B2 (en) 2019-03-29 2026-05-19 Board Of Regents, The University Of Texas System Compounds with anti-tumor activity against cancer cells bearing HER2 exon 21 insertions
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BR112021022828A2 (pt) * 2019-05-14 2022-04-12 Janssen Biotech Inc Terapias combinadas com anticorpos biespecíficos anti-egfr/c-met e inibidores de egfr tirosina-quinase de terceira geração
MY208668A (en) 2019-05-14 2025-05-23 Janssen Biotech Inc Combination therapies with bispecific anti-egfr/c-met antibodies and 3rd generation egfr tyrosine kinase inhibitors
US11850248B2 (en) 2019-05-14 2023-12-26 Yuhan Corporation Therapies with 3rd generation EGFR tyrosine kinase inhibitors
BR112022015140A2 (pt) 2020-02-12 2022-10-11 Janssen Biotech Inc Tratamento de pacientes que têm mutações de salto do éxon 14 de c-met
EP4204455A4 (fr) 2020-08-25 2024-10-16 Janssen Biotech, Inc. Traitement du cancer du poumon non à petites cellules présentant des mutations egfr
IL305700A (en) * 2021-03-09 2023-11-01 Janssen Biotech Inc Treatment of cancers lacking EFGR-activating mutations
EP4372001A4 (fr) * 2021-07-14 2025-02-12 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Molécule de liaison à l'antigène se liant spécifiquement à hgfr et egfr, et utilisation pharmaceutique de celle-ci
KR20240051145A (ko) * 2021-07-29 2024-04-19 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Kras 돌연변이 암의 치료를 위한 방법 및 조성물
KR102793991B1 (ko) 2021-10-06 2025-04-09 주식회사 엘지에너지솔루션 태양광 시스템과 연계하는 에너지 저장 시스템 및 에너지 저장 시스템의 제어 방법
US20230183360A1 (en) * 2021-12-09 2023-06-15 Janssen Biotech, Inc. Use of Amivantamab to Treat Colorectal Cancer
AU2024236678A1 (en) * 2023-03-13 2025-10-30 Janssen Biotech, Inc. Combination therapies with bi-specific anti-egfr/c-met antibodies and anti-pd-1 antibodies
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WO2026086844A1 (fr) * 2024-10-23 2026-04-30 正大天晴药业集团股份有限公司 Conjugué anticorps-médicament ciblant l'egfr et le c-met

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Also Published As

Publication number Publication date
JP2024153659A (ja) 2024-10-29
BR112021016149A2 (pt) 2021-10-13
US20230130600A1 (en) 2023-04-27
CA3131654A1 (fr) 2020-09-03
WO2020174370A2 (fr) 2020-09-03
US20200270351A1 (en) 2020-08-27
MX2021010265A (es) 2021-09-23
JOP20210233A1 (ar) 2023-01-30
CN113840842A (zh) 2021-12-24
WO2020174370A3 (fr) 2020-12-03
SG11202108311RA (en) 2021-09-29
NZ778579A (en) 2026-03-27
PH12021552030A1 (en) 2022-08-15
JP2022521610A (ja) 2022-04-11
IL285718A (en) 2021-10-31
JP7703448B2 (ja) 2025-07-07
KR20210132117A (ko) 2021-11-03
US20250236675A1 (en) 2025-07-24
US11459391B2 (en) 2022-10-04
AU2020229467A1 (en) 2021-08-12
EP3931224A2 (fr) 2022-01-05
JP2025084739A (ja) 2025-06-03
US12215161B2 (en) 2025-02-04
EP3931224A4 (fr) 2023-03-01

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