MA55480A - Procédés de fabrication de vecteurs viraux recombinants - Google Patents

Procédés de fabrication de vecteurs viraux recombinants

Info

Publication number
MA55480A
MA55480A MA055480A MA55480A MA55480A MA 55480 A MA55480 A MA 55480A MA 055480 A MA055480 A MA 055480A MA 55480 A MA55480 A MA 55480A MA 55480 A MA55480 A MA 55480A
Authority
MA
Morocco
Prior art keywords
methods
viral vectors
recombinant viral
making recombinant
making
Prior art date
Application number
MA055480A
Other languages
English (en)
Inventor
Maria-Fatima Bosch-Tubert
Laura Cervera-Gracia
Miguel Garcia-Martinez
Francesc Godia-Casablancas
Sonia Gutierrez-Granados
Xavier Leon-Madrenas
Maria Molas-Laplana
Original Assignee
Esteve Pharmaceuticals Sa
UNIV AUTòNOMA DE BARCELONA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Pharmaceuticals Sa, UNIV AUTòNOMA DE BARCELONA filed Critical Esteve Pharmaceuticals Sa
Publication of MA55480A publication Critical patent/MA55480A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151Methods of production or purification of viral material
    • C12N2750/14152Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA055480A 2019-03-28 2020-03-26 Procédés de fabrication de vecteurs viraux recombinants MA55480A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19382220 2019-03-28

Publications (1)

Publication Number Publication Date
MA55480A true MA55480A (fr) 2022-02-09

Family

ID=66175374

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055480A MA55480A (fr) 2019-03-28 2020-03-26 Procédés de fabrication de vecteurs viraux recombinants

Country Status (13)

Country Link
US (1) US12398403B2 (fr)
EP (1) EP3947654A1 (fr)
JP (1) JP7598333B2 (fr)
KR (1) KR20210148227A (fr)
CN (1) CN114466926B (fr)
AR (1) AR118493A1 (fr)
AU (1) AU2020247133B2 (fr)
BR (1) BR112021019022A2 (fr)
CA (1) CA3134429A1 (fr)
IL (1) IL286475A (fr)
MA (1) MA55480A (fr)
MX (1) MX2021011741A (fr)
WO (1) WO2020193698A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3947700A4 (fr) 2019-04-01 2023-01-04 Tenaya Therapeutics, Inc. Virus adéno-associé comprenant une capside modifiée
CN114364804A (zh) * 2019-04-12 2022-04-15 马萨诸塞眼科耳科诊所 用于改善腺相关病毒(aav)组装的方法和组合物
US12054738B2 (en) 2020-07-30 2024-08-06 Shape Therapeutics Inc. Stable cell lines for inducible production of rAAV virions
BR112023006305A2 (pt) 2020-10-09 2023-05-09 Tenaya Therapeutics Inc Métodos e composições de terapia gênica com placofilina-2
US11781156B2 (en) 2020-10-09 2023-10-10 Tenaya Therapeutics, Inc. Plakophillin-2 gene therapy methods and compositions
WO2023102736A1 (fr) * 2021-12-07 2023-06-15 中国科学院深圳先进技术研究院 Plasmide d'encapsidation de virus adéno-associé recombiné, virus adéno-associé recombiné et son application
WO2024191873A1 (fr) * 2023-03-10 2024-09-19 Biogen Ma Inc. Plasmides d'emballage pour la production d'aav
EP4606816A1 (fr) 2024-02-26 2025-08-27 Universitat Autónoma De Barcelona (UAB) Procédé de production de véhicules de thérapie génique dans des cellules de mammifères

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622856A (en) * 1995-08-03 1997-04-22 Avigen High efficiency helper system for AAV vector production
US6509150B1 (en) * 1999-03-05 2003-01-21 Universite De Nantes Compositions and methods for recombinant Adeno-Associated Virus production
DE10056210A1 (de) * 2000-11-13 2002-05-29 Arimedes Biotechnology Gmbh Virales Expressionssystem
AU2003265855A1 (en) * 2002-08-28 2004-03-19 University Of Florida Modified aav
EP1771571A2 (fr) * 2004-07-30 2007-04-11 Targeted Genetics Corporation Procedes de vaccination a base d'aav recombine
EP2394667A1 (fr) 2010-06-10 2011-12-14 Laboratorios Del Dr. Esteve, S.A. Vecteurs et séquences pour le traitement de maladies
HK1220488A1 (zh) * 2013-03-15 2017-05-05 The Children's Hospital Of Philadelphia 含有填充者/填充物多核苷酸序列的载体及其使用方法
EP3003391B1 (fr) * 2013-05-31 2021-09-22 The Regents of The University of California Variants de virus adéno-associés et leurs méthodes d'utilisation
EP3101125A1 (fr) 2015-06-05 2016-12-07 Laboratorios Del Dr. Esteve, S.A. Vecteurs viraux recombinés adéno-associés pour le traitement de la mucopolysaccharidose

Also Published As

Publication number Publication date
US20220186255A1 (en) 2022-06-16
US12398403B2 (en) 2025-08-26
AU2020247133A1 (en) 2021-10-14
CA3134429A1 (fr) 2020-10-01
TW202039856A (zh) 2020-11-01
WO2020193698A1 (fr) 2020-10-01
BR112021019022A2 (pt) 2021-11-30
CN114466926B (zh) 2025-01-17
JP2022527407A (ja) 2022-06-01
JP7598333B2 (ja) 2024-12-11
AU2020247133B2 (en) 2025-12-18
CN114466926A (zh) 2022-05-10
EP3947654A1 (fr) 2022-02-09
MX2021011741A (es) 2022-01-06
KR20210148227A (ko) 2021-12-07
AR118493A1 (es) 2021-10-20
IL286475A (en) 2021-10-31

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