MA55912A - Procédés de sélection auxotrophe - Google Patents

Procédés de sélection auxotrophe

Info

Publication number
MA55912A
MA55912A MA055912A MA55912A MA55912A MA 55912 A MA55912 A MA 55912A MA 055912 A MA055912 A MA 055912A MA 55912 A MA55912 A MA 55912A MA 55912 A MA55912 A MA 55912A
Authority
MA
Morocco
Prior art keywords
selection processes
auxotrophic selection
auxotrophic
processes
selection
Prior art date
Application number
MA055912A
Other languages
English (en)
Inventor
James Patterson
Matthew Porteus
Volker Wiebking
Original Assignee
Auxolytic Ltd
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auxolytic Ltd, Univ Leland Stanford Junior filed Critical Auxolytic Ltd
Publication of MA55912A publication Critical patent/MA55912A/fr

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/13—B-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22—Immunosuppressive or immunotolerising
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
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    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/03—Carboxy- and carbamoyltransferases (2.1.3)
    • C12Y201/03002—Aspartate carbamoyltransferase (2.1.3.2)
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    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/02003—Dihydroorotase (3.5.2.3)
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    • C12Y603/05—Carbon-nitrogen ligases with glutamine as amido-N-donor (6.3.5)
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    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01023—Orotidine-5'-phosphate decarboxylase (4.1.1.23)

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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
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MA055912A 2019-05-08 2020-05-08 Procédés de sélection auxotrophe MA55912A (fr)

Applications Claiming Priority (2)

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US201962844930P 2019-05-08 2019-05-08
US201962904725P 2019-09-24 2019-09-24

Publications (1)

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MA55912A true MA55912A (fr) 2022-03-16

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US (1) US20220325301A1 (fr)
EP (1) EP3966339A4 (fr)
JP (1) JP2022532535A (fr)
KR (1) KR20220018495A (fr)
CN (1) CN114026243A (fr)
AU (1) AU2020267598A1 (fr)
BR (1) BR112021022110A2 (fr)
CA (1) CA3138030A1 (fr)
IL (1) IL287886A (fr)
MA (1) MA55912A (fr)
MX (1) MX2021013522A (fr)
SG (1) SG11202111965YA (fr)
WO (1) WO2020227637A1 (fr)

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US20240093206A1 (en) * 2021-03-15 2024-03-21 490 BioTech, Inc. System of stable gene expression in cell lines and methods of making and using the same
CN113215168B (zh) * 2021-04-29 2023-04-28 华中科技大学同济医学院附属同济医院 一种卵巢癌细胞耐药的标志物及其应用
CN121620588A (zh) * 2023-07-31 2026-03-06 西格马-奥尔德里奇有限责任公司 经由丙氨酸生物合成途径的代谢选择
EP4516901A1 (fr) 2023-08-31 2025-03-05 Vilnius University Procédé de criblage d'enzymes hydrolytiques
CN119823942A (zh) * 2023-10-13 2025-04-15 中国科学院上海营养与健康研究所 一种促进调节性t细胞诱导的新方法

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US20030224411A1 (en) * 2003-03-13 2003-12-04 Stanton Lawrence W. Genes that are up- or down-regulated during differentiation of human embryonic stem cells
US9181529B2 (en) * 2010-10-19 2015-11-10 Cellular Dynamics International, Inc. Titration of differentiation medium components
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KR20220018495A (ko) 2022-02-15
EP3966339A1 (fr) 2022-03-16
CN114026243A (zh) 2022-02-08
BR112021022110A2 (pt) 2022-01-04
CA3138030A1 (fr) 2020-11-12
MX2021013522A (es) 2021-12-10
US20220325301A1 (en) 2022-10-13
EP3966339A4 (fr) 2023-01-25
WO2020227637A1 (fr) 2020-11-12
AU2020267598A1 (en) 2021-12-16
JP2022532535A (ja) 2022-07-15
SG11202111965YA (en) 2021-11-29
IL287886A (en) 2022-01-01

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