MA56386A - Polythérapie comprenant de l'acétyl-leucine et du miglustat - Google Patents

Polythérapie comprenant de l'acétyl-leucine et du miglustat

Info

Publication number
MA56386A
MA56386A MA056386A MA56386A MA56386A MA 56386 A MA56386 A MA 56386A MA 056386 A MA056386 A MA 056386A MA 56386 A MA56386 A MA 56386A MA 56386 A MA56386 A MA 56386A
Authority
MA
Morocco
Prior art keywords
polytherapy
miglustat
leucine
including acetyl
acetyl
Prior art date
Application number
MA056386A
Other languages
English (en)
Other versions
MA56386B1 (fr
Inventor
Mallory Factor
Michael Strupp
Original Assignee
Intrabio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrabio Ltd filed Critical Intrabio Ltd
Publication of MA56386A publication Critical patent/MA56386A/fr
Publication of MA56386B1 publication Critical patent/MA56386B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA56386A 2019-06-28 2020-06-26 Polythérapie comprenant de l'acétyl-leucine et du miglustat pour le traitement d'une maladie lysosomale MA56386B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962868383P 2019-06-28 2019-06-28
US201962931003P 2019-11-05 2019-11-05
EP20736444.9A EP3989962B1 (fr) 2019-06-28 2020-06-26 Polythérapie comprenant de l'acétyl-leucine et du miglustat pour le traitement d'une maladie lysosomale
PCT/IB2020/056096 WO2020261230A1 (fr) 2019-06-28 2020-06-26 Polythérapie comprenant de l'acétyl-leucine et du miglustat

Publications (2)

Publication Number Publication Date
MA56386A true MA56386A (fr) 2022-05-04
MA56386B1 MA56386B1 (fr) 2025-10-31

Family

ID=71452519

Family Applications (1)

Application Number Title Priority Date Filing Date
MA56386A MA56386B1 (fr) 2019-06-28 2020-06-26 Polythérapie comprenant de l'acétyl-leucine et du miglustat pour le traitement d'une maladie lysosomale

Country Status (16)

Country Link
US (1) US20220362189A1 (fr)
EP (2) EP3989962B1 (fr)
DK (1) DK3989962T3 (fr)
ES (1) ES3048174T3 (fr)
FI (1) FI3989962T3 (fr)
HR (1) HRP20251256T1 (fr)
HU (1) HUE073420T2 (fr)
LT (1) LT3989962T (fr)
MA (1) MA56386B1 (fr)
MD (1) MD3989962T2 (fr)
PL (1) PL3989962T3 (fr)
PT (1) PT3989962T (fr)
RS (1) RS67283B1 (fr)
SI (1) SI3989962T1 (fr)
SM (1) SMT202500369T1 (fr)
WO (1) WO2020261230A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201709459D0 (en) 2017-06-14 2017-07-26 Intrabio Ltd Treatment for migraine
EP3886986A1 (fr) 2018-12-06 2021-10-06 IntraBio Ltd Analogues deutérés d'acétyl-leucine
CN118409027B (zh) * 2024-07-02 2024-09-10 成都市食品检验研究院 一种食品中1-脱氧野尻霉素的含量检测方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2588130T (lt) 2010-06-25 2016-12-12 Shire Human Genetic Therapies, Inc. Terapinės priemonės pristatymas cns
DK3359146T3 (en) 2016-08-11 2019-04-08 Intrabio Ltd PHARMACEUTICAL COMPOSITIONS AND USES AGAINST LYSOSOMAL STORAGE DISEASES

Also Published As

Publication number Publication date
EP3989962B1 (fr) 2025-08-27
ES3048174T3 (en) 2025-12-09
EP4650003A2 (fr) 2025-11-19
SMT202500369T1 (it) 2025-11-10
EP3989962A1 (fr) 2022-05-04
PT3989962T (pt) 2025-10-09
PL3989962T3 (pl) 2025-11-17
MA56386B1 (fr) 2025-10-31
SI3989962T1 (sl) 2025-11-28
RS67283B1 (sr) 2025-11-28
HUE073420T2 (hu) 2026-01-28
EP4650003A3 (fr) 2026-01-21
WO2020261230A1 (fr) 2020-12-30
LT3989962T (lt) 2025-10-10
DK3989962T3 (da) 2025-10-13
MD3989962T2 (ro) 2025-12-31
FI3989962T3 (fi) 2025-10-08
HRP20251256T1 (hr) 2025-12-05
US20220362189A1 (en) 2022-11-17

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