MA71254A - Sels d'inhibiteurs de sos1 - Google Patents

Sels d'inhibiteurs de sos1

Info

Publication number
MA71254A
MA71254A MA71254A MA71254A MA71254A MA 71254 A MA71254 A MA 71254A MA 71254 A MA71254 A MA 71254A MA 71254 A MA71254 A MA 71254A MA 71254 A MA71254 A MA 71254A
Authority
MA
Morocco
Prior art keywords
sos1 inhibitor
inhibitor salts
salts
sos1
inhibitor
Prior art date
Application number
MA71254A
Other languages
English (en)
Inventor
Anthony IVETAC
Xiaolun Wang
Svitlana KULYK
Christopher Ronald Smith
Matthew Arnold Marx
John Michael KETCHAM
Aaron Craig BURNS
John David Lawson
Original Assignee
Mirati Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mirati Therapeutics, Inc. filed Critical Mirati Therapeutics, Inc.
Publication of MA71254A publication Critical patent/MA71254A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13Dicarboxylic acids
    • C07C57/15Fumaric acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA71254A 2022-06-24 2023-06-23 Sels d'inhibiteurs de sos1 MA71254A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263355567P 2022-06-24 2022-06-24
PCT/US2023/026118 WO2023250165A1 (fr) 2022-06-24 2023-06-23 Sels d'inhibiteurs de sos1
EP23827900.4A EP4543450A1 (fr) 2022-06-24 2023-06-23 Sels d'inhibiteurs de sos1

Publications (1)

Publication Number Publication Date
MA71254A true MA71254A (fr) 2025-04-30

Family

ID=89380432

Family Applications (1)

Application Number Title Priority Date Filing Date
MA71254A MA71254A (fr) 2022-06-24 2023-06-23 Sels d'inhibiteurs de sos1

Country Status (14)

Country Link
US (1) US20250382290A1 (fr)
EP (1) EP4543450A1 (fr)
JP (1) JP2025521356A (fr)
KR (1) KR20250027745A (fr)
CN (1) CN119546304A (fr)
AU (1) AU2023287691A1 (fr)
CA (1) CA3259322A1 (fr)
CL (1) CL2024003934A1 (fr)
CO (1) CO2024017767A2 (fr)
IL (1) IL317847A (fr)
MA (1) MA71254A (fr)
MX (1) MX2024015455A (fr)
PE (1) PE20251073A1 (fr)
WO (1) WO2023250165A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202547461A (zh) 2024-05-17 2025-12-16 美商銳新醫藥公司 Ras抑制劑
WO2025255438A1 (fr) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Procédés de traitement d'une maladie ou d'un trouble lié à la protéine ras
WO2025265060A1 (fr) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Compositions thérapeutiques et procédés de gestion d'effets liés au traitement
WO2026006747A1 (fr) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Inhibiteurs de ras
WO2026015790A1 (fr) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Méthodes de traitement d'une maladie ou d'un trouble lié à ras
WO2026015801A1 (fr) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Méthodes de traitement d'une maladie ou d'un trouble liés à ras
WO2026015796A1 (fr) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Méthodes de traitement d'une maladie ou d'un trouble lié à ras
WO2026015825A1 (fr) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Utilisation d'un inhibiteur de ras pour traiter le cancer du pancréas
WO2026050446A1 (fr) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Inhibiteurs de ras
WO2026072904A2 (fr) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions et méthodes de traitement du cancer du poumon

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2742940B1 (fr) * 2012-12-13 2017-07-26 IP Gesellschaft für Management mbH Sel de fumarate de (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-l-aza-bicyclo-[2.2.2]octane destinés à être administrés une fois par jour, deux fois par jour ou trois fois par jour
PH12022551513A1 (en) * 2019-12-20 2023-04-24 Mirati Therapeutics Inc Sos1 inhibitors

Also Published As

Publication number Publication date
CA3259322A1 (fr) 2023-12-28
CL2024003934A1 (es) 2025-05-02
JP2025521356A (ja) 2025-07-08
EP4543450A1 (fr) 2025-04-30
KR20250027745A (ko) 2025-02-27
CO2024017767A2 (es) 2025-01-13
US20250382290A1 (en) 2025-12-18
WO2023250165A1 (fr) 2023-12-28
PE20251073A1 (es) 2025-04-10
AU2023287691A1 (en) 2025-02-06
CN119546304A (zh) 2025-02-28
IL317847A (en) 2025-02-01
MX2024015455A (es) 2025-02-10

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