MA71622A - Domaines de liaison à l'antigène cd98hc et leurs utilisations - Google Patents
Domaines de liaison à l'antigène cd98hc et leurs utilisationsInfo
- Publication number
- MA71622A MA71622A MA71622A MA71622A MA71622A MA 71622 A MA71622 A MA 71622A MA 71622 A MA71622 A MA 71622A MA 71622 A MA71622 A MA 71622A MA 71622 A MA71622 A MA 71622A
- Authority
- MA
- Morocco
- Prior art keywords
- cd98hc
- antigen
- binding domains
- domains
- binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263369885P | 2022-07-29 | 2022-07-29 | |
| US202363489675P | 2023-03-10 | 2023-03-10 | |
| US202363495514P | 2023-04-11 | 2023-04-11 | |
| PCT/US2023/071238 WO2024026471A1 (fr) | 2022-07-29 | 2023-07-28 | Domaines de liaison à l'antigène cd98hc et leurs utilisations |
| EP23758167.3A EP4561614A1 (fr) | 2022-07-29 | 2023-07-28 | Domaines de liaison à l'antigène cd98hc et leurs utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA71622A true MA71622A (fr) | 2025-05-30 |
Family
ID=87760570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA71622A MA71622A (fr) | 2022-07-29 | 2023-07-28 | Domaines de liaison à l'antigène cd98hc et leurs utilisations |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250270341A1 (fr) |
| EP (1) | EP4561614A1 (fr) |
| JP (1) | JP2025528751A (fr) |
| CN (1) | CN119584983A (fr) |
| AU (1) | AU2023316021A1 (fr) |
| CA (1) | CA3261511A1 (fr) |
| MA (1) | MA71622A (fr) |
| MX (1) | MX2025000569A (fr) |
| WO (1) | WO2024026471A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025166042A1 (fr) * | 2024-01-31 | 2025-08-07 | Alector Llc | Domaines de liaison à l'antigène cd98hc et leurs utilisations |
| WO2025166045A1 (fr) | 2024-01-31 | 2025-08-07 | Alector Llc | ENZYMES DE β-GLUCOCÉRÉBROSIDASE, PROTÉINES DE FUSION ET COMPLEXES LES COMPRENANT, ET LEURS PROCÉDÉS D'UTILISATION |
| WO2025166040A1 (fr) | 2024-01-31 | 2025-08-07 | Alector Llc | Protéines de liaison multi-spécifiques qui se lient à gpnmb et à une cible de barrière hémato-encéphalique et procédés pour les utiliser |
| WO2025247301A1 (fr) * | 2024-05-30 | 2025-12-04 | Sironax Switzerland Gmbh | Nouveaux anticorps spécifiques d'une chaîne lourde cd98 et leurs procédés d'utilisation |
| CN120842376A (zh) * | 2025-07-28 | 2025-10-28 | 郑州伊美诺生物技术有限公司 | 广谱特异性抗体及其应用 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| EP0216846B2 (fr) | 1985-04-01 | 1995-04-26 | Celltech Limited | Lignee cellulaire de myelomes transformee et procede d'expression d'un gene codant un polypeptide eucaryotique employant cette lignee |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| EP0368684B2 (fr) | 1988-11-11 | 2004-09-29 | Medical Research Council | Clonage de séquences d'immunoglobulines de domaines variables. |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| CA2095633C (fr) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Methode d'enrichissement de proteines variantes aux proprietes liantes alterees |
| US5571894A (en) | 1991-02-05 | 1996-11-05 | Ciba-Geigy Corporation | Recombinant antibodies specific for a growth factor receptor |
| EP1400536A1 (fr) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Procédé pour fabriquer des anticorps humanisés |
| GB9114948D0 (en) | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
| MX9204374A (es) | 1991-07-25 | 1993-03-01 | Idec Pharma Corp | Anticuerpo recombinante y metodo para su produccion. |
| FI941572A7 (fi) | 1991-10-07 | 1994-05-27 | Oncologix Inc | Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä |
| US5869619A (en) | 1991-12-13 | 1999-02-09 | Xoma Corporation | Modified antibody variable domains |
| EP0571613B1 (fr) | 1991-12-13 | 2003-09-17 | Xoma Corporation | Materiels et methodes pour preparer des domaines variables d'anticorps modifies et leurs utilisations therapeutiques |
| CA2372813A1 (fr) | 1992-02-06 | 1993-08-19 | L.L. Houston | Proteine fixatrice biosynthetique pour marqueur du cancer |
| US6174666B1 (en) | 1992-03-27 | 2001-01-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of eliminating inhibitory/instability regions from mRNA |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| ATE299938T1 (de) | 1997-05-02 | 2005-08-15 | Genentech Inc | Ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen |
| US7951917B1 (en) | 1997-05-02 | 2011-05-31 | Genentech, Inc. | Method for making multispecific antibodies having heteromultimeric and common components |
| US6610833B1 (en) | 1997-11-24 | 2003-08-26 | The Institute For Human Genetics And Biochemistry | Monoclonal human natural antibodies |
| DK1034298T3 (da) | 1997-12-05 | 2012-01-30 | Scripps Research Inst | Humanisering af murint antistof |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| CA2430013C (fr) | 2000-11-30 | 2011-11-22 | Medarex, Inc. | Rongeurs transgeniques et transchromosomiques pour la fabrication d'anticorps humains |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| EP1740615B1 (fr) | 2004-03-31 | 2014-11-05 | Genentech, Inc. | Anticorps anti-tgf-beta humanises |
| WO2006028936A2 (fr) | 2004-09-02 | 2006-03-16 | Genentech, Inc. | Molecules heteromultimeriques |
| TW200812616A (en) | 2006-05-09 | 2008-03-16 | Genentech Inc | Binding polypeptides with optimized scaffolds |
| CN100592373C (zh) | 2007-05-25 | 2010-02-24 | 群康科技(深圳)有限公司 | 液晶显示面板驱动装置及其驱动方法 |
| JP6157046B2 (ja) | 2008-01-07 | 2017-07-05 | アムジェン インコーポレイテッド | 静電的ステアリング(electrostaticsteering)効果を用いた抗体Fcヘテロ二量体分子を作製するための方法 |
| US9527926B2 (en) | 2010-05-14 | 2016-12-27 | Rinat Neuroscience Corp. | Heterodimeric proteins and methods for producing and purifying them |
| CA2813493C (fr) | 2010-10-11 | 2019-07-09 | University Of Zurich | Anticorps anti-tau humain |
| ES2758994T3 (es) | 2010-11-05 | 2020-05-07 | Zymeworks Inc | Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc |
| AU2013322710A1 (en) | 2012-09-25 | 2015-04-16 | Glenmark Pharmaceuticals S.A. | Purification of hetero-dimeric immunoglobulins |
| EP2914634B1 (fr) | 2012-11-02 | 2017-12-06 | Zymeworks Inc. | Structures cristallines de domaines fc hétérodimères |
| JP6385357B2 (ja) | 2012-11-27 | 2018-09-05 | アジュ ユニバーシティー インダストリー−アカデミック コーオペレイション ファウンデーションAjou University Industry−Academic Cooperation Foundation | 抗体重鎖不変部位の異種二量体、高効率の形成を誘導するch3ドメイン変異体対、その作製方法および用途 |
| US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
| EP3594240B1 (fr) | 2013-05-20 | 2023-12-06 | F. Hoffmann-La Roche AG | Anticorps du récepteur anti-transferrine et procédés d'utilisation |
| TWI599358B (zh) | 2014-09-16 | 2017-09-21 | 美國禮來大藥廠 | 組合療法 |
| WO2016087650A1 (fr) | 2014-12-05 | 2016-06-09 | Merck Patent Gmbh | Anticorps à domaine échangé |
| KR20170085595A (ko) * | 2014-12-10 | 2017-07-24 | 제넨테크, 인크. | 혈뇌 장벽 수용체 항체 및 사용 방법 |
| WO2018027025A1 (fr) | 2016-08-03 | 2018-02-08 | Oncomed Pharmaceuticals, Inc. | Agent liant cd40 et utilisations associées |
| BR112018014281A2 (pt) | 2016-11-15 | 2018-12-18 | H Lundbeck As | agentes, usos e métodos para o tratamento da sinucleinopatia |
| US12258414B2 (en) | 2018-06-22 | 2025-03-25 | Ossianix, Inc. | Anti-CD98hc VNARs for crossing the blood brain barrier and type IV VNAR libraries |
| CA3179922A1 (fr) * | 2020-04-08 | 2021-10-14 | Janssen Biotech, Inc. | Anticorps anti-cd98 et leurs utilisations |
-
2023
- 2023-07-28 WO PCT/US2023/071238 patent/WO2024026471A1/fr not_active Ceased
- 2023-07-28 MA MA71622A patent/MA71622A/fr unknown
- 2023-07-28 CN CN202380054112.2A patent/CN119584983A/zh active Pending
- 2023-07-28 EP EP23758167.3A patent/EP4561614A1/fr active Pending
- 2023-07-28 CA CA3261511A patent/CA3261511A1/fr active Pending
- 2023-07-28 AU AU2023316021A patent/AU2023316021A1/en active Pending
- 2023-07-28 JP JP2025504645A patent/JP2025528751A/ja active Pending
-
2025
- 2025-01-14 MX MX2025000569A patent/MX2025000569A/es unknown
- 2025-01-28 US US19/039,230 patent/US20250270341A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025528751A (ja) | 2025-09-02 |
| MX2025000569A (es) | 2025-02-10 |
| CA3261511A1 (fr) | 2024-02-01 |
| EP4561614A1 (fr) | 2025-06-04 |
| WO2024026471A9 (fr) | 2024-11-07 |
| CN119584983A (zh) | 2025-03-07 |
| AU2023316021A1 (en) | 2025-03-06 |
| US20250270341A1 (en) | 2025-08-28 |
| WO2024026471A1 (fr) | 2024-02-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA71622A (fr) | Domaines de liaison à l'antigène cd98hc et leurs utilisations | |
| MA71630A (fr) | Domaines de liaison à l'antigène du récepteur de la transferrine et leurs utilisations | |
| EP4126958A4 (fr) | Molécules multispécifiques de liaison à l'antigène à activation immunitaire et leurs utilisations | |
| EP4441098A4 (fr) | Unité de liaison à l'antigène ccr8 et ses utilisations | |
| EP4291187A4 (fr) | Agents de dégradation d'irak4 et leurs utilisations | |
| EP4188951A4 (fr) | Molécules de liaison à un coronavirus multimériques et leurs utilisations | |
| EP4132969A4 (fr) | Molécules de liaison à l'antigène anti-mésothéline et leurs utilisations | |
| EP3863605A4 (fr) | Vecteurs aav1 et leurs utilisations pour le traitement d'indications otiques | |
| EP4126956A4 (fr) | Molécules multispécifiques de liaison à l'antigène ciblant la claudine 6 et leurs utilisations | |
| EP4121055A4 (fr) | Agents de dégradation de stat et leurs utilisations | |
| EP3966321A4 (fr) | Ligases de protéine spécifiques à l'asx et leurs utilisations | |
| EP3902838A4 (fr) | Fractions de liaison à cd30, récepteurs d'antigènes chimériques et leurs utilisations | |
| EP4097223A4 (fr) | Agents de liaison à strad et leurs utilisations | |
| EP3954774A4 (fr) | Édition dirigée vers un site d'arn à l'aide d'enzymes d'édition d'arn construites artificiellement et utilisations associées | |
| EP4263611A4 (fr) | Molécules de liaison à ace6 et leurs utilisations | |
| EP4330414A4 (fr) | Capsides aav et leurs utilisations | |
| EP4200335A4 (fr) | Compositions d'anticorps anti-cd5 et leurs utilisations | |
| EP4100431A4 (fr) | Protéines actriib à variant et leurs utilisations | |
| EP4114856A4 (fr) | Molécules de liaison à l'antigène et leurs utilisations | |
| EP4225303A4 (fr) | Agents dégradeurs de stat et leurs utilisations | |
| MA71559A (fr) | Molécules de liaison à l'antigène anti-steap1 et leurs utilisations | |
| EP4257617A4 (fr) | Protéine de liaison à l'antigène ciblant cd70 et son utilisation | |
| EP4384543A4 (fr) | Protéines de liaison à l'antigène et leurs utilisations | |
| EP4374093A4 (fr) | Systèmes de pignons segmentés et leurs procédés d'installation | |
| EP4294299A4 (fr) | Systèmes et méthodes de traitement d'une articulation sacro-iliaque |