MC1970A1 - Derives acyles - Google Patents

Derives acyles

Info

Publication number
MC1970A1
MC1970A1 MC882001A MC2001A MC1970A1 MC 1970 A1 MC1970 A1 MC 1970A1 MC 882001 A MC882001 A MC 882001A MC 2001 A MC2001 A MC 2001A MC 1970 A1 MC1970 A1 MC 1970A1
Authority
MC
Monaco
Prior art keywords
methyl
amino
carbamoyl
oxo
lower alkyl
Prior art date
Application number
MC882001A
Other languages
English (en)
French (fr)
Inventor
Gotschi Erwin
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1970A1 publication Critical patent/MC1970A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MC882001A 1987-08-14 1988-08-11 Derives acyles MC1970A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH313387 1987-08-14
CH472687 1987-12-03

Publications (1)

Publication Number Publication Date
MC1970A1 true MC1970A1 (fr) 1989-09-29

Family

ID=25692275

Family Applications (1)

Application Number Title Priority Date Filing Date
MC882001A MC1970A1 (fr) 1987-08-14 1988-08-11 Derives acyles

Country Status (15)

Country Link
US (2) US5036064A (da)
EP (1) EP0303172A3 (da)
JP (1) JPS6466190A (da)
KR (1) KR890003776A (da)
AU (1) AU614984B2 (da)
DK (1) DK455288A (da)
FI (1) FI883766A7 (da)
HU (1) HUT47944A (da)
IL (1) IL87374A0 (da)
MC (1) MC1970A1 (da)
NO (1) NO883590L (da)
NZ (1) NZ225754A (da)
PH (1) PH25646A (da)
PT (1) PT88274B (da)
YU (1) YU156388A (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
US5030724A (en) * 1990-01-22 1991-07-09 E. R. Squibb & Sons, Inc. Monobactam hydrazides containing catechol sulfonic acid groups
US20040197408A1 (en) * 2002-12-30 2004-10-07 Angiotech International Ag Amino acids in micelle preparation
US7537532B2 (en) * 2007-05-16 2009-05-26 Young Carl D Handle for implement and method
KR101719556B1 (ko) * 2011-03-30 2017-03-24 주식회사 레고켐 바이오사이언스 신규한 세파로스포린 유도체 및 이를 함유하는 의약 조성물
PT3616695T (pt) 2011-09-09 2024-11-18 Merck Sharp & Dohme Ceftolozano/tazobactam para tratar infeções intrapulmonares
US9290515B2 (en) 2011-10-04 2016-03-22 Shionogi & Co., Ltd Cephem derivative having catechol group
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
KR101821868B1 (ko) 2012-11-19 2018-01-24 미쯔이가가꾸가부시끼가이샤 폴리에스테르 수지 조성물과 그 제조 방법, 그것을 포함하는 카메라 모듈
US20140274996A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Tazobactam and ceftolozane antibiotic compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
PE20160048A1 (es) 2013-03-15 2016-02-12 Merck Sharp & Dohme Composiciones antibioticas de ceftolozano
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
AU586215B2 (en) * 1985-01-21 1989-07-06 Nippon Pharmaceutical Development Institute Company Limited Novel ```-lactam antibiotics
FI872879A7 (fi) * 1986-07-21 1988-01-22 Sankei Yakuhin Kk --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes.
DE3840011A1 (de) * 1988-11-26 1990-05-31 Merck Patent Gmbh Benzoxazinderivate

Also Published As

Publication number Publication date
PH25646A (en) 1991-08-21
US5036064A (en) 1991-07-30
IL87374A0 (en) 1989-01-31
DK455288A (da) 1989-02-15
NZ225754A (en) 1991-04-26
EP0303172A2 (de) 1989-02-15
JPS6466190A (en) 1989-03-13
KR890003776A (ko) 1989-04-18
FI883766A7 (fi) 1989-02-15
US5319140A (en) 1994-06-07
PT88274A (pt) 1989-06-30
AU2055488A (en) 1989-04-20
NO883590D0 (no) 1988-08-12
EP0303172A3 (de) 1991-05-15
NO883590L (no) 1989-02-15
DK455288D0 (da) 1988-08-12
FI883766A0 (fi) 1988-08-12
PT88274B (pt) 1995-03-01
HUT47944A (en) 1989-04-28
AU614984B2 (en) 1991-09-19
YU156388A (en) 1990-02-28

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