MC2397A1 - Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide - Google Patents

Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide

Info

Publication number
MC2397A1
MC2397A1 MC2323A MC2323A MC2397A1 MC 2397 A1 MC2397 A1 MC 2397A1 MC 2323 A MC2323 A MC 2323A MC 2323 A MC2323 A MC 2323A MC 2397 A1 MC2397 A1 MC 2397A1
Authority
MC
Monaco
Prior art keywords
peptide
amino acid
radioactive
affinity
technetium
Prior art date
Application number
MC2323A
Other languages
English (en)
French (fr)
Inventor
Ikuya Seki
Yoshitoshi Itaya
Yoshifumi Shirakami
Komei Washino
Original Assignee
Nihon Mediphysics Co Ltd
Antisoma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd, Antisoma Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of MC2397A1 publication Critical patent/MC2397A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1018—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MC2323A 1994-06-07 1995-11-28 Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide MC2397A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14865594 1994-06-07

Publications (1)

Publication Number Publication Date
MC2397A1 true MC2397A1 (fr) 1996-07-26

Family

ID=15457667

Family Applications (1)

Application Number Title Priority Date Filing Date
MC2323A MC2397A1 (fr) 1994-06-07 1995-11-28 Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide

Country Status (11)

Country Link
US (1) US5827498A (de)
EP (1) EP0700930B1 (de)
KR (1) KR960000250A (de)
AT (1) ATE175977T1 (de)
AU (1) AU684348B2 (de)
CA (1) CA2151099A1 (de)
DE (1) DE69507408T2 (de)
DK (1) DK0700930T3 (de)
ES (1) ES2138111T3 (de)
MC (1) MC2397A1 (de)
TW (1) TW394777B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2165228A1 (en) * 1994-12-27 1996-06-28 Yoshitoshi Itaya Metal chelate forming peptides and use thereof
BR112013015001B1 (pt) * 2010-12-14 2021-10-13 Recepta Biopharma S.A. Peptídeo antitumor isolado ou sintético, composição farmacêutica, e, usos de um peptídeo
EP3434276B1 (de) 2012-06-06 2024-10-30 Pepkon Verfahren und pharmazeutische zusammensetzung zur verwendung bei der behandlung von krebs
PT3380495T (pt) * 2015-11-24 2021-08-19 Transfert Plus Sec Compostos peptídicos e conjugados peptídicos para o tratamento de cancro através de quimioterapia mediada por recetores
AU2018321825A1 (en) * 2017-08-19 2020-03-05 Ohio State Innovation Foundation Novel peptide-based cancer imaging agents
CN107550864B (zh) * 2017-08-23 2020-12-18 科笛生物医药(上海)有限公司 Eppt多肽-聚乙二醇-磷脂复合膜材料、其制备方法及主动靶向脂质体递药系统和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322678A (en) * 1988-02-17 1994-06-21 Neorx Corporation Alteration of pharmacokinetics of proteins by charge modification
EP0442926A1 (de) * 1988-11-10 1991-08-28 Imperial Cancer Research Technology Limited Polypeptide
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
JP2774378B2 (ja) * 1991-02-08 1998-07-09 ダイアテク,インコーポレイテッド 映像用テクネチウム−99m標識化ポリペプチド
GB9108652D0 (en) * 1991-04-23 1991-06-12 Antisoma Ltd Immunoreactive compounds

Also Published As

Publication number Publication date
TW394777B (en) 2000-06-21
CA2151099A1 (en) 1995-12-08
DE69507408D1 (de) 1999-03-04
ES2138111T3 (es) 2000-01-01
DE69507408T2 (de) 2000-05-18
EP0700930B1 (de) 1999-11-03
US5827498A (en) 1998-10-27
AU2049995A (en) 1995-12-14
ATE175977T1 (de) 1999-02-15
DK0700930T3 (da) 1999-09-13
KR960000250A (ko) 1996-01-25
EP0700930A1 (de) 1996-03-13
AU684348B2 (en) 1997-12-11

Similar Documents

Publication Publication Date Title
US12569578B2 (en) RI-labeled humanized antibody
EP3689892B1 (de) Radioaktives arzneimittel
AU2011354599B2 (en) Radiolabled HER2 binding peptides
US10960089B2 (en) Radiolabeled drug
Ren et al. PET of malignant melanoma using 18F-labeled metallopeptides
WO1998047524A9 (en) Gastrin receptor-avid peptide conjugates
US5785948A (en) Metal chelate forming peptides and use thereof represented by three amino acid sequences
CN105579434A (zh) 基于乙烯基砜的18f标记组合物和方法及其用途
Rosita et al. Fluorine and rhenium substituted ghrelin analogues as potential imaging probes for the growth hormone secretagogue receptor
JP2512604B2 (ja) 心房性ナトリウム利尿因子(anf)のキレ―ト誘導体
CN107308466B (zh) 具有肿瘤血管靶向性的多肽、分子探针及其制备方法和应用
US5827498A (en) Tumor affinity peptide, and radioactive diagnostic agent and radioactive therapeutic agent containing the peptide
Vaidyanathan et al. N ε-(3-[* I] iodobenzoyl)-Lys5-N α-maleimido-Gly1-GEEEK ([* I] IB-Mal-D-GEEEK): a radioiodinated prosthetic group containing negatively charged D-glutamates for labeling internalizing monoclonal antibodies
TW200812627A (en) Compounds as aptamer-dimers and their uses in diagnosis and therapy
EP4421087A1 (de) Klammerhaltige polypeptide und anwendung davon
KR20230174243A (ko) β선을 방출하는 핵종으로 표지된 인간화 항체
JP4318985B2 (ja) ソマトスタチンアナログ誘導体およびその利用
CN120118155B (zh) 靶向pd-l1的多肽类正电子探针及其制备方法和应用
JP2012082166A (ja) 動脈硬化診断用分子イメージングプローブ
JPH0853494A (ja) 腫瘍親和性ペプチド、該ペプチドを含有してなる放射性診断剤および放射性治療剤
JP3866317B2 (ja) 金属キレート形成性ペプチド、その用途及びその製造方法
FR2649488A1 (fr) Fragments d'anticorps monoclonaux specifiques de la presence de leucocytes actives - leur procede d'obtention et leur application dans le cas de rejet de greffe