MD20150101A2 - Săruri de hidroclorură a unui compus antibiotic - Google Patents
Săruri de hidroclorură a unui compus antibiotic Download PDFInfo
- Publication number
- MD20150101A2 MD20150101A2 MDA20150101A MD20150101A MD20150101A2 MD 20150101 A2 MD20150101 A2 MD 20150101A2 MD A20150101 A MDA20150101 A MD A20150101A MD 20150101 A MD20150101 A MD 20150101A MD 20150101 A2 MD20150101 A2 MD 20150101A2
- Authority
- MD
- Moldova
- Prior art keywords
- hydrochloride salts
- antibiotic compound
- compounds
- compound
- relates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Invenţia se referă la un compus cu formula I:,în care x se află în intervalul de la aproximativ 1 până la aproximativ 2. Invenţia se referă, de asemenea, la compoziţii farmaceutice cu conţinut de astfel de compuşi, la procedee de obţinere şi la metode de utilizare a unor astfel de compuşi, de exemplu, în tratamentul infecţiei bacteriene.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779065P | 2013-03-13 | 2013-03-13 | |
| PCT/US2014/021064 WO2014158952A1 (en) | 2013-03-13 | 2014-03-06 | Hydrochloride salts of an antibiotic compound |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| MD20150101A2 true MD20150101A2 (ro) | 2016-02-29 |
| MD4599B1 MD4599B1 (ro) | 2018-11-30 |
| MD4599C1 MD4599C1 (ro) | 2019-06-30 |
Family
ID=50483481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20150101A MD4599C1 (ro) | 2013-03-13 | 2014-03-06 | Săruri de hidroclorură a unui compus antibiotic |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US9161990B2 (ro) |
| EP (1) | EP2968446B1 (ro) |
| JP (3) | JP6482523B2 (ro) |
| KR (1) | KR20150126659A (ro) |
| CN (1) | CN105120883B (ro) |
| AR (1) | AR095044A1 (ro) |
| AU (1) | AU2014241481B9 (ro) |
| BR (1) | BR112015022716A2 (ro) |
| CA (1) | CA2902720A1 (ro) |
| CY (1) | CY1119316T1 (ro) |
| DK (1) | DK2968446T3 (ro) |
| EA (1) | EA027282B1 (ro) |
| ES (1) | ES2633964T3 (ro) |
| GE (2) | GEP20186874B (ro) |
| HR (1) | HRP20171188T1 (ro) |
| HU (1) | HUE033738T2 (ro) |
| IL (1) | IL240663A0 (ro) |
| LT (1) | LT2968446T (ro) |
| MD (1) | MD4599C1 (ro) |
| ME (1) | ME02854B (ro) |
| MX (1) | MX361984B (ro) |
| PH (1) | PH12015502060A1 (ro) |
| PL (1) | PL2968446T3 (ro) |
| PT (1) | PT2968446T (ro) |
| RS (1) | RS56141B1 (ro) |
| SG (1) | SG11201507235YA (ro) |
| SI (1) | SI2968446T1 (ro) |
| SM (1) | SMT201700369T1 (ro) |
| TW (1) | TWI608845B (ro) |
| UA (1) | UA115086C2 (ro) |
| WO (1) | WO2014158952A1 (ro) |
| ZA (1) | ZA201506748B (ro) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016154100A1 (en) * | 2015-03-24 | 2016-09-29 | Elevance Renewable Sciences, Inc. | Polyol esters of metathesized fatty acids and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4434287A (en) * | 1975-02-20 | 1984-02-28 | Ciba-Geigy Corporation | Cephalosporin derivatives |
| AR228726A1 (es) | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
| US4626534A (en) | 1984-07-23 | 1986-12-02 | Eli Lilly And Company | Pharmaceutical formulation |
| DE3801179A1 (de) | 1988-01-18 | 1989-07-27 | Hoechst Ag | Stabilisierung von cephalosporinderivaten durch trocknung mit einem stabilisator sowie stabile zubereitungsformen mit cephalosporinderivaten |
| JPH0331449A (ja) | 1989-06-27 | 1991-02-12 | Yamaha Corp | リードフレーム用Ｆｅ―Ｎｉ合金 |
| ES2059947T3 (es) | 1989-09-30 | 1994-11-16 | Eisai Co Ltd | Preparados inyectables que contienen cefalosporina y utilizacion de los mismos. |
| JPH03193735A (ja) | 1989-12-22 | 1991-08-23 | Shionogi & Co Ltd | グリコペプチド系抗生物質の安定化組成物 |
| JP4142149B2 (ja) | 1997-07-10 | 2008-08-27 | 明治製菓株式会社 | バンコマイシンの凍結乾燥製剤 |
| TWI335332B (en) * | 2001-10-12 | 2011-01-01 | Theravance Inc | Cross-linked vancomycin-cephalosporin antibiotics |
| ATE473986T1 (de) * | 2003-04-16 | 2010-07-15 | Sandoz Ag | Verfahren zur herstellung von cefepim |
| JP2007500222A (ja) | 2003-05-23 | 2007-01-11 | セラヴァンス インコーポレーテッド | 架橋グリコペプチド−セファロスポリン抗生物質 |
| US6878868B2 (en) | 2003-06-24 | 2005-04-12 | Mcmillan Stacy L. | Portable high-hat device |
| DE602004012269T2 (de) | 2003-07-11 | 2009-04-30 | Theravance, Inc., South San Francisco | Quervernetzte glycopeptid-cephalosporin-antibiotika |
| TWI342312B (en) * | 2003-10-22 | 2011-05-21 | Theravance Inc | Hydrochloride salts of a glycopeptide phosphonate derivative |
| EP1656930A1 (en) | 2004-11-10 | 2006-05-17 | Basilea Pharmaceutica AG | Stabilized freeze-dried formulation for cephalosporin derivatives |
| US20080103121A1 (en) | 2006-10-30 | 2008-05-01 | Gole Dilip J | Cephalosporin derivative formulation |
| FR2932177B1 (fr) | 2008-06-06 | 2012-11-30 | Inst Francais Du Petrole | Procede d'hydrogenation selective sur un catalyseur contenant de l'or. |
| JP2010105965A (ja) | 2008-10-30 | 2010-05-13 | Taiyo Yakuhin Kogyo Kk | バンコマイシン製剤 |
| WO2011035108A1 (en) | 2009-09-17 | 2011-03-24 | Eagle Pharmaceuticals, Inc. | Formulations of daptomycin |
| WO2011062676A1 (en) | 2009-11-23 | 2011-05-26 | Eagle Pharmaceuticals, Inc. | Formulations of daptomycin |
-
2014
- 2014-03-06 LT LTEP14717248.0T patent/LT2968446T/lt unknown
- 2014-03-06 GE GEAP201413957A patent/GEP20186874B/en unknown
- 2014-03-06 HR HRP20171188TT patent/HRP20171188T1/hr unknown
- 2014-03-06 ES ES14717248.0T patent/ES2633964T3/es active Active
- 2014-03-06 SM SM20170369T patent/SMT201700369T1/it unknown
- 2014-03-06 EA EA201591697A patent/EA027282B1/ru unknown
- 2014-03-06 RS RS20170621A patent/RS56141B1/sr unknown
- 2014-03-06 KR KR1020157027597A patent/KR20150126659A/ko not_active Withdrawn
- 2014-03-06 US US14/198,956 patent/US9161990B2/en active Active
- 2014-03-06 BR BR112015022716A patent/BR112015022716A2/pt not_active Application Discontinuation
- 2014-03-06 MD MDA20150101A patent/MD4599C1/ro active IP Right Grant
- 2014-03-06 SI SI201430302T patent/SI2968446T1/sl unknown
- 2014-03-06 PL PL14717248T patent/PL2968446T3/pl unknown
- 2014-03-06 SG SG11201507235YA patent/SG11201507235YA/en unknown
- 2014-03-06 TW TW103107730A patent/TWI608845B/zh not_active IP Right Cessation
- 2014-03-06 EP EP14717248.0A patent/EP2968446B1/en active Active
- 2014-03-06 AU AU2014241481A patent/AU2014241481B9/en not_active Ceased
- 2014-03-06 JP JP2016500713A patent/JP6482523B2/ja active Active
- 2014-03-06 CN CN201480013969.0A patent/CN105120883B/zh active Active
- 2014-03-06 DK DK14717248.0T patent/DK2968446T3/en active
- 2014-03-06 CA CA2902720A patent/CA2902720A1/en not_active Abandoned
- 2014-03-06 WO PCT/US2014/021064 patent/WO2014158952A1/en not_active Ceased
- 2014-03-06 HU HUE14717248A patent/HUE033738T2/hu unknown
- 2014-03-06 MX MX2015012170A patent/MX361984B/es active IP Right Grant
- 2014-03-06 PT PT147172480T patent/PT2968446T/pt unknown
- 2014-03-06 GE GEAP201813957A patent/GEAP201813957A/en unknown
- 2014-03-06 UA UAA201509921A patent/UA115086C2/uk unknown
- 2014-03-06 ME MEP-2017-133A patent/ME02854B/me unknown
- 2014-03-07 AR ARP140100742A patent/AR095044A1/es unknown
-
2015
- 2015-08-18 IL IL240663A patent/IL240663A0/en not_active IP Right Cessation
- 2015-09-11 ZA ZA2015/06748A patent/ZA201506748B/en unknown
- 2015-09-11 PH PH12015502060A patent/PH12015502060A1/en unknown
-
2017
- 2017-02-17 JP JP2017028372A patent/JP2017082016A/ja not_active Withdrawn
- 2017-07-28 CY CY20171100810T patent/CY1119316T1/el unknown
-
2018
- 2018-08-17 JP JP2018153560A patent/JP2018177817A/ja not_active Withdrawn
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued |