MD20160061A2 - Sistem de livrare a medicamentului compus din particule multiple - Google Patents

Sistem de livrare a medicamentului compus din particule multiple Download PDF

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Publication number
MD20160061A2
MD20160061A2 MDA20160061A MD20160061A MD20160061A2 MD 20160061 A2 MD20160061 A2 MD 20160061A2 MD A20160061 A MDA20160061 A MD A20160061A MD 20160061 A MD20160061 A MD 20160061A MD 20160061 A2 MD20160061 A2 MD 20160061A2
Authority
MD
Moldova
Prior art keywords
drug delivery
delivery system
particulate drug
microgel particles
disperse
Prior art date
Application number
MDA20160061A
Other languages
English (en)
Russian (ru)
Inventor
Гонсалес Роберто Карлос Браво
Фелипе Жозе Оливейра ВАРУМ
КРУИФ Жан Кендалл ДЕ
Мартин КУНЦ
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of MD20160061A2 publication Critical patent/MD20160061A2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Invenţia se referă la un sistem dispers de livrare a medicamentului, care include particule de microgel, ce conţin un ingredient farmaceutic activ. Particulele de microgel sunt dispersate într-o compoziţie neapoasă lichidă. De asemenea, se revendică un procedeu de obţinere a unui astfel de sistem dispers, particulele de microgel din care acesta constă şi capsule umplute cu un astfel de sistem.
MDA20160061A 2013-11-13 2014-11-13 Sistem de livrare a medicamentului compus din particule multiple MD20160061A2 (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13192657 2013-11-13
EP14157427 2014-03-03
PCT/EP2014/074501 WO2015071366A1 (en) 2013-11-13 2014-11-13 Multi-particulate drug delivery system

Publications (1)

Publication Number Publication Date
MD20160061A2 true MD20160061A2 (ro) 2016-10-31

Family

ID=51900424

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20160061A MD20160061A2 (ro) 2013-11-13 2014-11-13 Sistem de livrare a medicamentului compus din particule multiple

Country Status (19)

Country Link
US (1) US20160287521A1 (ro)
EP (1) EP3068381B1 (ro)
JP (2) JP2016537352A (ro)
KR (1) KR20160085269A (ro)
CN (1) CN105899197A (ro)
AU (1) AU2014350208B2 (ro)
CA (1) CA2930277A1 (ro)
CL (1) CL2016001148A1 (ro)
CR (1) CR20160263A (ro)
CU (1) CU20160069A7 (ro)
EA (1) EA201600387A1 (ro)
HK (1) HK1224219A1 (ro)
MD (1) MD20160061A2 (ro)
MX (1) MX2016006275A (ro)
NZ (1) NZ720512A (ro)
PE (1) PE20160850A1 (ro)
PH (1) PH12016500847A1 (ro)
TN (1) TN2016000160A1 (ro)
WO (1) WO2015071366A1 (ro)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11510877B2 (en) 2017-10-10 2022-11-29 Capsugel Belgium Nv Gelling multiparticulates
MX2020009824A (es) 2018-07-25 2021-01-15 Alteogen Inc Nuevas variantes de hialuronidasa y composicion farmaceutica que comprende la misma.
KR102154565B1 (ko) * 2018-11-13 2020-09-10 한국화학연구원 천연 오일을 함유하는 미세캡슐 및 이의 제조방법
KR102650991B1 (ko) 2019-03-25 2024-03-27 (주)알테오젠 인간 히알루로니다제 ph20의 변이체와 약물을 포함하는 피하투여용 약학 조성물
CN111388759B (zh) * 2020-04-28 2021-09-07 四川大学 一种骨水泥复合材料及其制备方法
US12221638B2 (en) 2020-08-07 2025-02-11 Alteogen Inc. Method for producing recombinant hyaluronidase
WO2024101250A1 (ja) * 2022-11-11 2024-05-16 公立大学法人名古屋市立大学 マイクロゲル製造方法、及び加飾性マイクロゲル集合体の製造方法
KR102847026B1 (ko) * 2023-08-25 2025-08-18 에바바이오 주식회사 프릴링 방법을 적용하여 제조한 다중소포성 리포좀의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0657653B2 (ja) * 1985-08-23 1994-08-03 藤沢薬品工業株式会社 油性懸濁型直腸注入剤
HK1002252A1 (en) * 1991-04-02 1998-08-07 Biotech Australia Pty. Limited Oral delivery systems for microparticles
US5879712A (en) * 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
FR2754177B1 (fr) * 1996-10-07 1999-08-06 Sanofi Sa Microspheres pharmaceutiques d'acide valproique pour administration orale
ES2246238T3 (es) * 1999-06-07 2006-02-16 Altana Pharma Ag Nueva preparacion y forma de administracion que comprende un inhibidor de las bombas de protones labil en medio acido.
FR2814380B1 (fr) * 2000-09-25 2002-11-08 Serobiologiques Lab Sa Poudre de microcapsules et procede d'obtention
JP4046313B2 (ja) * 2001-01-12 2008-02-13 株式会社資生堂 油中水型乳化組成物およびこれを用いた乳化化粧料
US7993749B2 (en) * 2005-12-16 2011-08-09 University Of Kansas Nanoparticles comprising a nanoparticle template and a polymer shell having an amide side chain, and method of making thereof
US7651770B2 (en) * 2005-12-16 2010-01-26 The University Of Kansas Nanoclusters for delivery of therapeutics
PT103476B (pt) 2006-05-10 2008-09-19 Univ De Coimbra Processo de produção e isolamento de micro- e nanopartículas poliméricas contendo macromoléculas de natureza hidrofílica e termolábil
KR101591820B1 (ko) * 2007-11-14 2016-02-05 더 유니버시티 오브 퀸스랜드 마이크로입자 제조장치 및 방법
EP2111854A1 (en) * 2008-04-22 2009-10-28 Lek Pharmaceuticals D.D. Self-microemulsifying systems incorporated into liquid core microcapsules

Also Published As

Publication number Publication date
EA201600387A1 (ru) 2016-08-31
PE20160850A1 (es) 2016-09-23
CN105899197A (zh) 2016-08-24
AU2014350208B2 (en) 2017-09-07
CA2930277A1 (en) 2015-05-21
JP2019112413A (ja) 2019-07-11
WO2015071366A1 (en) 2015-05-21
AU2014350208A1 (en) 2016-06-16
US20160287521A1 (en) 2016-10-06
MX2016006275A (es) 2017-01-05
EP3068381A1 (en) 2016-09-21
NZ720512A (en) 2018-01-26
CU20160069A7 (es) 2016-10-28
JP2016537352A (ja) 2016-12-01
PH12016500847A1 (en) 2016-06-20
KR20160085269A (ko) 2016-07-15
TN2016000160A1 (en) 2017-10-06
CL2016001148A1 (es) 2016-11-25
CR20160263A (es) 2017-04-05
HK1224219A1 (zh) 2017-08-18
EP3068381B1 (en) 2019-09-11

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FA9A Abandonment or withdrawal of application (patent for invention)