MD20160061A2 - Sistem de livrare a medicamentului compus din particule multiple - Google Patents

Sistem de livrare a medicamentului compus din particule multiple Download PDF

Info

Publication number
MD20160061A2
MD20160061A2 MDA20160061A MD20160061A MD20160061A2 MD 20160061 A2 MD20160061 A2 MD 20160061A2 MD A20160061 A MDA20160061 A MD A20160061A MD 20160061 A MD20160061 A MD 20160061A MD 20160061 A2 MD20160061 A2 MD 20160061A2
Authority
MD
Moldova
Prior art keywords
drug delivery
delivery system
particulate drug
microgel particles
disperse
Prior art date
Application number
MDA20160061A
Other languages
English (en)
Russian (ru)
Inventor
Гонсалес Роберто Карлос Браво
Фелипе Жозе Оливейра ВАРУМ
КРУИФ Жан Кендалл ДЕ
Мартин КУНЦ
Original Assignee
Tillotts Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tillotts Pharma Ag filed Critical Tillotts Pharma Ag
Publication of MD20160061A2 publication Critical patent/MD20160061A2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Invenţia se referă la un sistem dispers de livrare a medicamentului, care include particule de microgel, ce conţin un ingredient farmaceutic activ. Particulele de microgel sunt dispersate într-o compoziţie neapoasă lichidă. De asemenea, se revendică un procedeu de obţinere a unui astfel de sistem dispers, particulele de microgel din care acesta constă şi capsule umplute cu un astfel de sistem.
MDA20160061A 2013-11-13 2014-11-13 Sistem de livrare a medicamentului compus din particule multiple MD20160061A2 (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13192657 2013-11-13
EP14157427 2014-03-03
PCT/EP2014/074501 WO2015071366A1 (en) 2013-11-13 2014-11-13 Multi-particulate drug delivery system

Publications (1)

Publication Number Publication Date
MD20160061A2 true MD20160061A2 (ro) 2016-10-31

Family

ID=51900424

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20160061A MD20160061A2 (ro) 2013-11-13 2014-11-13 Sistem de livrare a medicamentului compus din particule multiple

Country Status (19)

Country Link
US (1) US20160287521A1 (ro)
EP (1) EP3068381B1 (ro)
JP (2) JP2016537352A (ro)
KR (1) KR20160085269A (ro)
CN (1) CN105899197A (ro)
AU (1) AU2014350208B2 (ro)
CA (1) CA2930277A1 (ro)
CL (1) CL2016001148A1 (ro)
CR (1) CR20160263A (ro)
CU (1) CU20160069A7 (ro)
EA (1) EA201600387A1 (ro)
HK (1) HK1224219A1 (ro)
MD (1) MD20160061A2 (ro)
MX (1) MX2016006275A (ro)
NZ (1) NZ720512A (ro)
PE (1) PE20160850A1 (ro)
PH (1) PH12016500847A1 (ro)
TN (1) TN2016000160A1 (ro)
WO (1) WO2015071366A1 (ro)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019072877A1 (en) 2017-10-10 2019-04-18 Capsugel Belgium Nv GETTING MULTIPARTICULAR COMPOSITIONS
MX2020009824A (es) 2018-07-25 2021-01-15 Alteogen Inc Nuevas variantes de hialuronidasa y composicion farmaceutica que comprende la misma.
KR102154565B1 (ko) * 2018-11-13 2020-09-10 한국화학연구원 천연 오일을 함유하는 미세캡슐 및 이의 제조방법
CN112203642B (zh) 2019-03-25 2025-03-07 阿特根公司 用于皮下注射的包含人透明质酸酶ph20变体和药物的药物组合物
TW202615652A (zh) 2020-01-23 2026-04-16 南韓商阿特根公司 新穎的具有改善的穩定性的玻尿酸酶變異體及含有其的醫藥組合物
CN111388759B (zh) * 2020-04-28 2021-09-07 四川大学 一种骨水泥复合材料及其制备方法
WO2022031093A1 (ko) 2020-08-07 2022-02-10 (주)알테오젠 재조합 히알루로니다제의 생산 방법
JPWO2024101250A1 (ro) * 2022-11-11 2024-05-16
KR102847026B1 (ko) * 2023-08-25 2025-08-18 에바바이오 주식회사 프릴링 방법을 적용하여 제조한 다중소포성 리포좀의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0657653B2 (ja) * 1985-08-23 1994-08-03 藤沢薬品工業株式会社 油性懸濁型直腸注入剤
DK0531497T3 (da) * 1991-04-02 1998-03-23 Biotech Australia Pty Ltd Orale indgivelsessystemer til mikropartikler
US5879712A (en) * 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
FR2754177B1 (fr) * 1996-10-07 1999-08-06 Sanofi Sa Microspheres pharmaceutiques d'acide valproique pour administration orale
EE200100660A (et) * 1999-06-07 2003-04-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Ravimvorm happe suhtes labiilsete toimeainete jaoks, toimeaine üksus, selle valmistamismeetod ja mikrokerake
FR2814380B1 (fr) * 2000-09-25 2002-11-08 Serobiologiques Lab Sa Poudre de microcapsules et procede d'obtention
JP4046313B2 (ja) * 2001-01-12 2008-02-13 株式会社資生堂 油中水型乳化組成物およびこれを用いた乳化化粧料
US7993749B2 (en) * 2005-12-16 2011-08-09 University Of Kansas Nanoparticles comprising a nanoparticle template and a polymer shell having an amide side chain, and method of making thereof
MX2008007697A (es) * 2005-12-16 2008-09-26 Univ Kansas Nanocumulos para la distribucion de farmacos.
PT103476B (pt) * 2006-05-10 2008-09-19 Univ De Coimbra Processo de produção e isolamento de micro- e nanopartículas poliméricas contendo macromoléculas de natureza hidrofílica e termolábil
JP5526033B2 (ja) * 2007-11-14 2014-06-18 ザ ユニバーシティ オブ クィーンズランド 微粒子製造装置および微粒子製造方法
EP2111854A1 (en) 2008-04-22 2009-10-28 Lek Pharmaceuticals D.D. Self-microemulsifying systems incorporated into liquid core microcapsules

Also Published As

Publication number Publication date
MX2016006275A (es) 2017-01-05
HK1224219A1 (zh) 2017-08-18
CL2016001148A1 (es) 2016-11-25
WO2015071366A1 (en) 2015-05-21
EP3068381B1 (en) 2019-09-11
AU2014350208B2 (en) 2017-09-07
JP2016537352A (ja) 2016-12-01
CA2930277A1 (en) 2015-05-21
PE20160850A1 (es) 2016-09-23
JP2019112413A (ja) 2019-07-11
AU2014350208A1 (en) 2016-06-16
TN2016000160A1 (en) 2017-10-06
CU20160069A7 (es) 2016-10-28
PH12016500847A1 (en) 2016-06-20
CN105899197A (zh) 2016-08-24
US20160287521A1 (en) 2016-10-06
EA201600387A1 (ru) 2016-08-31
KR20160085269A (ko) 2016-07-15
EP3068381A1 (en) 2016-09-21
NZ720512A (en) 2018-01-26
CR20160263A (es) 2017-04-05

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FA9A Abandonment or withdrawal of application (patent for invention)