MD2985G2 - Process for isothiocyanatochalcone obtaining - Google Patents
Process for isothiocyanatochalcone obtaining Download PDFInfo
- Publication number
- MD2985G2 MD2985G2 MDA20040244A MD20040244A MD2985G2 MD 2985 G2 MD2985 G2 MD 2985G2 MD A20040244 A MDA20040244 A MD A20040244A MD 20040244 A MD20040244 A MD 20040244A MD 2985 G2 MD2985 G2 MD 2985G2
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- isothiocyanatochalcone
- isothiocyanatochalcones
- dimethylthioureidochalcones
- deaminized
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- JWINEQDNKCFKFN-UHFFFAOYSA-N 3-(2-isothiocyanatophenyl)-1-phenylprop-2-en-1-one Chemical compound N(=C=S)C1=C(C=CC=C1)C=CC(=O)C1=CC=CC=C1 JWINEQDNKCFKFN-UHFFFAOYSA-N 0.000 title abstract 2
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- -1 4-acetylphenyl Chemical group 0.000 abstract 1
- DQFBYFPFKXHELB-UHFFFAOYSA-N Chalcone Natural products C=1C=CC=CC=1C(=O)C=CC1=CC=CC=C1 DQFBYFPFKXHELB-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000003934 aromatic aldehydes Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001789 chalcones Chemical class 0.000 abstract 1
- 235000005513 chalcones Nutrition 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 150000003585 thioureas Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to processes for obtaining isothiocyanatochalcones which may be used as precursors for the synthesis of certain chalcones of medicinal and cosmetic use.The claimed process includes condensation of 1,1-dimethyl-3-(3- or 4-acetylphenyl)thioureas with substituted aromatic aldehydes, with obtaining of N,N-dimethylthioureidochalcones which are deaminized in an inert solution at their heating with mineral acids (H2SO4, HCl in dioxane) or with acetic anhydride (in benzene or toluole), taken respectively in equimolar ratio.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20040244A MD2985G2 (en) | 2004-10-04 | 2004-10-04 | Process for isothiocyanatochalcone obtaining |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20040244A MD2985G2 (en) | 2004-10-04 | 2004-10-04 | Process for isothiocyanatochalcone obtaining |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD2985F1 MD2985F1 (en) | 2006-02-28 |
| MD2985G2 true MD2985G2 (en) | 2006-10-31 |
Family
ID=36002229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20040244A MD2985G2 (en) | 2004-10-04 | 2004-10-04 | Process for isothiocyanatochalcone obtaining |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD2985G2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4077C1 (en) * | 2010-01-18 | 2011-07-31 | Государственный Университет Молд0 | Process for obtaining N, N-dimethylthioureidobenzoic acids |
-
2004
- 2004-10-04 MD MDA20040244A patent/MD2985G2/en not_active IP Right Cessation
Non-Patent Citations (2)
| Title |
|---|
| M. Dzurilla, P. Kristian. Isothiocyanates and their syntetic producers. Collection of Czechoslovak Chemical Communications, 1969, V.35, N2, p. 145-151 * |
| W. Davey, J. R. Gwilt. Chalcones and related compounds. Journal of chemical society. Part 1. 1957, p. 73-78 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4077C1 (en) * | 2010-01-18 | 2011-07-31 | Государственный Университет Молд0 | Process for obtaining N, N-dimethylthioureidobenzoic acids |
Also Published As
| Publication number | Publication date |
|---|---|
| MD2985F1 (en) | 2006-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |