MD2985G2 - Способ получения изотиоцианатохалконов - Google Patents
Способ получения изотиоцианатохалконов Download PDFInfo
- Publication number
- MD2985G2 MD2985G2 MDA20040244A MD20040244A MD2985G2 MD 2985 G2 MD2985 G2 MD 2985G2 MD A20040244 A MDA20040244 A MD A20040244A MD 20040244 A MD20040244 A MD 20040244A MD 2985 G2 MD2985 G2 MD 2985G2
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- isothiocyanatochalcone
- isothiocyanatochalcones
- dimethylthioureidochalcones
- deaminized
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- JWINEQDNKCFKFN-UHFFFAOYSA-N 3-(2-isothiocyanatophenyl)-1-phenylprop-2-en-1-one Chemical compound N(=C=S)C1=C(C=CC=C1)C=CC(=O)C1=CC=CC=C1 JWINEQDNKCFKFN-UHFFFAOYSA-N 0.000 title abstract 2
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- -1 4-acetylphenyl Chemical group 0.000 abstract 1
- DQFBYFPFKXHELB-UHFFFAOYSA-N Chalcone Natural products C=1C=CC=CC=1C(=O)C=CC1=CC=CC=C1 DQFBYFPFKXHELB-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000003934 aromatic aldehydes Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001789 chalcones Chemical class 0.000 abstract 1
- 235000005513 chalcones Nutrition 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 150000003585 thioureas Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Abstract
Изобретение относится к способам получения изотиоцианатохалконов, которые могут быть использованы в качестве предшественников для синтеза некоторых халконов медицинского или косметического назначения.Заявленный способ включает конденсацию 1,1-диметил-3-(3- или 4-ацетилфенил)тиомочевин с замещёнными ароматическими альдегидами, с получением N,N-диметилтиоуреидохалконов, которые дезаминируются в инертном растворителе при их нагревании с минеральными кислотами (H2SO4, HC1 в диоксане) или с уксусным ангидридом (в бензоле или толуоле), взятыми соответственно в эквимолярном соотношении.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20040244A MD2985G2 (ru) | 2004-10-04 | 2004-10-04 | Способ получения изотиоцианатохалконов |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20040244A MD2985G2 (ru) | 2004-10-04 | 2004-10-04 | Способ получения изотиоцианатохалконов |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD2985F1 MD2985F1 (en) | 2006-02-28 |
| MD2985G2 true MD2985G2 (ru) | 2006-10-31 |
Family
ID=36002229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20040244A MD2985G2 (ru) | 2004-10-04 | 2004-10-04 | Способ получения изотиоцианатохалконов |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD2985G2 (ru) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4077C1 (ru) * | 2010-01-18 | 2011-07-31 | Государственный Университет Молд0 | Способ получения N, N-диметилтиоуреидобензойных кислот |
-
2004
- 2004-10-04 MD MDA20040244A patent/MD2985G2/ru not_active IP Right Cessation
Non-Patent Citations (2)
| Title |
|---|
| M. Dzurilla, P. Kristian. Isothiocyanates and their syntetic producers. Collection of Czechoslovak Chemical Communications, 1969, V.35, N2, p. 145-151 * |
| W. Davey, J. R. Gwilt. Chalcones and related compounds. Journal of chemical society. Part 1. 1957, p. 73-78 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4077C1 (ru) * | 2010-01-18 | 2011-07-31 | Государственный Университет Молд0 | Способ получения N, N-диметилтиоуреидобензойных кислот |
Also Published As
| Publication number | Publication date |
|---|---|
| MD2985F1 (en) | 2006-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE50207584D1 (de) | Zusammensetzungen für die Herstellung von Formkörpern aus feinteiligen Materialien | |
| SE0301010D0 (sv) | Novel compounds | |
| SE0301009D0 (sv) | Novel compounds | |
| NL300933I2 (nl) | Letermovir | |
| CY1111757T1 (el) | Παραγωγα ξανθινης ως εκλεκτικοι αναστολεις ημ74α | |
| CL2003002683A1 (es) | Enantiomeros s de compuestos derivados del acido (2s)-3-4(-{2-amino-2-oxoetoxi}fenil)-2-etoxipropanoico; proceso de preparacion; compuestos intermediarios; composicion farmaceutica; y su uso para el tratamiento o prevencion de trastornos de lipidos, | |
| CY1109084T1 (el) | Προϊον ζαχαροπλαστικης με χαμηλα λιπαρα | |
| EP1578722A4 (en) | KINASEINHIBITOR SCAFFOLD AND METHOD FOR THE PRODUCTION THEREOF | |
| CY1110812T1 (el) | Παραγωγα διφαινυλοξυοξικου οξεος για τη θεραπεια αναπνευστικων διαταραχων | |
| MX277587B (es) | Poliesteres de alta funcionalidad, altamente ramificados o hiper-ramificados, la produccion de los mismos y el uso de los mismos. | |
| DE602006020327D1 (de) | 2-phenoxy-n-(1,3,4-thiadizol-2-yl)pyridin-3-aminder-hemmer zur behandlung thromboembolischer erkrankungen | |
| CL2007000789A1 (es) | Compuestos derivados de malonamida, inhibidores de la gamma-secretasa; proceso de preparacion; composicion farmaceutica; y su uso en el tratamiento de la enfermedad de alzheimer. | |
| NO20041886L (no) | Fremgangsmate for fremstilling av maursyreformiater | |
| DE60108042D1 (de) | Prozesse zur Herstellung von pulverförmigen Schlagzäh-Modifizierern | |
| TNSN07277A1 (en) | Pharmaceutical compounds | |
| ATE496036T1 (de) | Zwischenprodukte für die herstellung von pramipexol | |
| WO2008052173A8 (en) | Novel h5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use | |
| MY152928A (en) | Process for preparing at least one target product by partial oxidation and/or ammoxidation of propylene | |
| ATE347555T1 (de) | 6-aminomorphinanderivate, herstellungsverfahren dafür und deren verwendung | |
| BR0310115B1 (pt) | processo para preparaÇço de dinitrilas de Ácido fenilmalânico. | |
| DE602006011295D1 (de) | Verfahren zur herstellung von salzen von 4-ää5-ä(cyclopropylamino)carbonylü-2-methylphenylüaminoü-5-methyl-n-propylpyrroloä2,1-füä1,2,4ütriazin-6-carboxamid und damit hergestellte neue stabile formen | |
| NO20081988L (no) | Fremgangsmate for fremstilling av polymelkesyre | |
| GT200800066A (es) | Derivados de 9-cloro-15-deoxiprostaglandina, procedimiento para su preparacion y su uso como medicamento. | |
| MD2985G2 (ru) | Способ получения изотиоцианатохалконов | |
| DE602005008626D1 (de) | Verfahren zur herstellung aromatischer thiophenylketone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |