MD3032F1 - Copper (II) naphthalidyosemicarbazides containing sulfanylamides - Google Patents

Copper (II) naphthalidyosemicarbazides containing sulfanylamides Download PDF

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Publication number
MD3032F1
MD3032F1 MDA20050322A MD20050322A MD3032F1 MD 3032 F1 MD3032 F1 MD 3032F1 MD A20050322 A MDA20050322 A MD A20050322A MD 20050322 A MD20050322 A MD 20050322A MD 3032 F1 MD3032 F1 MD 3032F1
Authority
MD
Moldova
Prior art keywords
copper
compounds
invention consists
exhibits
naphthalidyosemicarbazides
Prior art date
Application number
MDA20050322A
Other languages
Romanian (ro)
Other versions
MD3032G2 (en
Inventor
Aurelian Gulea
Viorel Prisacari
Victor Tapcov
Svetlana Buraciova
Stela SPINU
Natalia Bejenari
Original Assignee
Universitatea De Stat Din Moldova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitatea De Stat Din Moldova filed Critical Universitatea De Stat Din Moldova
Priority to MDA20050322A priority Critical patent/MD3032G2/en
Publication of MD3032F1 publication Critical patent/MD3032F1/en
Publication of MD3032G2 publication Critical patent/MD3032G2/en

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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/20—Fertilizers of biological origin, e.g. guano or fertilizers made from animal corpses

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Inventia se refera la chimie si medicina, si anume la un sir de compusi interni de cupru biologic activi din clasa tiosemicarbazidatilor metalelor de tranzitie care pot gasi aplicare in practica medicala si medicina veterinara in calitate de preparate antimicrobiene. Esenta inventiei consta in obtinerea naftalidentiosemicarbazidatilor de cupru(II) care contin sulfanilamide cu formula: I - XIunde R = H (I - V), C6H5 (VI - IX);Compusii I-IX manifesta activitate antimicrobiana.Rezultatul inventiei consta in sinteza compusilor I-IX, care au toxicitate joasa, manifesta activitate antimicrobiana fata de majoritatea microorganismelor, iar in cazul tulpinilor gram-pozitive ale culturilor testate manifesta activitate bacteriostatica si bactericida de 16...160 ori mai inalta. The invention relates to chemistry and medicine, namely to a number of biologically active internal copper compounds in the thiosemicarbazidate class of transition metals that can find application in medical practice and veterinary medicine as antimicrobial preparations. The essence of the invention consists in obtaining the naphthalidentesemicarbazidates of copper (II) containing sulphanilamides of the formula: I - XIunde R = H (I - V), C6H5 (VI - IX); Compounds I-IX show antimicrobial activity. The result of the invention consists in the synthesis of compounds. I-IX, which have low toxicity, exhibits antimicrobial activity against most microorganisms, and in the case of the gram-positive strains of the cultures tested, it exhibits bacteriostatic and bactericidal activity of 16 ... 160 times higher.

MDA20050322A 2005-10-31 2005-10-31 Sulfanilamide-containing naphthalidenethiosemicarbazidates of copper(II) MD3032G2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20050322A MD3032G2 (en) 2005-10-31 2005-10-31 Sulfanilamide-containing naphthalidenethiosemicarbazidates of copper(II)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20050322A MD3032G2 (en) 2005-10-31 2005-10-31 Sulfanilamide-containing naphthalidenethiosemicarbazidates of copper(II)

Publications (2)

Publication Number Publication Date
MD3032F1 true MD3032F1 (en) 2006-04-30
MD3032G2 MD3032G2 (en) 2006-11-30

Family

ID=36202596

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20050322A MD3032G2 (en) 2005-10-31 2005-10-31 Sulfanilamide-containing naphthalidenethiosemicarbazidates of copper(II)

Country Status (1)

Country Link
MD (1) MD3032G2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4133C1 (en) * 2010-07-19 2012-05-31 Государственный Университет Молд0 [(2-Carbamotioylhydrazone)propionato(2-)]-(4-aminobenzenesulfonamide)copper, manifesting antimicrobial activity against bacteria of the genus Bacillus cereus
MD4179C1 (en) * 2011-05-23 2013-02-28 Государственный Университет Молд0 Coordinative compounds of copper(II), containing 4-phenylthiosemicarbazone 2-formylpyridine and sulfonylamides, exhibiting antimicrobial activity against bacteria of Bacillus cereus species
MD4252C1 (en) * 2012-05-31 2014-05-31 Государственный Университет Молд0 Catena-(µ-nitrato)[µ-(2-hydroxybenzylidene)-4-prop-2-en-1-ylthiocarbazone-S]silver with antimicrobial activity against bacteria Salmonella abony

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4112C1 (en) * 2010-05-17 2011-12-31 Государственный Университет Молд0 Coordinative compounds of copper with 4-(dimethylphenyl)-thiosemicarbazones of 2-formylpyridine
MD4127C1 (en) * 2010-10-06 2012-04-30 Государственный Университет Молд0 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD2942C2 (en) * 2004-04-27 2006-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Di(µ-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4133C1 (en) * 2010-07-19 2012-05-31 Государственный Университет Молд0 [(2-Carbamotioylhydrazone)propionato(2-)]-(4-aminobenzenesulfonamide)copper, manifesting antimicrobial activity against bacteria of the genus Bacillus cereus
MD4179C1 (en) * 2011-05-23 2013-02-28 Государственный Университет Молд0 Coordinative compounds of copper(II), containing 4-phenylthiosemicarbazone 2-formylpyridine and sulfonylamides, exhibiting antimicrobial activity against bacteria of Bacillus cereus species
MD4252C1 (en) * 2012-05-31 2014-05-31 Государственный Университет Молд0 Catena-(µ-nitrato)[µ-(2-hydroxybenzylidene)-4-prop-2-en-1-ylthiocarbazone-S]silver with antimicrobial activity against bacteria Salmonella abony

Also Published As

Publication number Publication date
MD3032G2 (en) 2006-11-30

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees