MD4014B1 - Complecsi polioxometalati cu activitate antitumorala - Google Patents
Complecsi polioxometalati cu activitate antitumorala Download PDFInfo
- Publication number
- MD4014B1 MD4014B1 MDA20090046A MD20090046A MD4014B1 MD 4014 B1 MD4014 B1 MD 4014B1 MD A20090046 A MDA20090046 A MD A20090046A MD 20090046 A MD20090046 A MD 20090046A MD 4014 B1 MD4014 B1 MD 4014B1
- Authority
- MD
- Moldova
- Prior art keywords
- antitumor activity
- synthesis
- complex compounds
- polyoxometalate
- polyoxometalate complex
- Prior art date
Links
- 239000013460 polyoxometalate Substances 0.000 title abstract 4
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000003786 synthesis reaction Methods 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000003748 selenium group Chemical group *[Se]* 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Inventia se refera la sinteza compusilor complecsi polioxometalati cu activitate antitumorala. Esenta inventiei consta in sinteza compusilor complecsi polioxometalati cu formula:Rezultatul inventiei consta in sinteza unor compusi complecsi polioxometalati cu un efect de inhibare a celulelor tumorale de 85…92% la o concentratie de 10…100 MyM.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20090046A MD4014C2 (ro) | 2009-04-23 | 2009-04-23 | Complecşi polioxometalaţi cu activitate antitumorală |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20090046A MD4014C2 (ro) | 2009-04-23 | 2009-04-23 | Complecşi polioxometalaţi cu activitate antitumorală |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD4014B1 true MD4014B1 (ro) | 2010-02-26 |
| MD4014C2 MD4014C2 (ro) | 2010-09-30 |
Family
ID=43568899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20090046A MD4014C2 (ro) | 2009-04-23 | 2009-04-23 | Complecşi polioxometalaţi cu activitate antitumorală |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD4014C2 (ro) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4282C1 (ro) * | 2012-12-11 | 2014-11-30 | ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ | Utilizarea complecşilor polioxometalaţi cu atomi de seleniu centrali în calitate de compuşi cu activitate antitumorală |
| DE102015000814A1 (de) | 2015-01-21 | 2016-07-21 | Smart Material Printing B.V. | Biozide Ausrüstung von Gegenständen mit Polyoxometallat-Mikro- und/oder -Nanopartikeln |
| DE102015000812A1 (de) | 2015-01-21 | 2016-07-21 | Smart Material Printing B.V. | Wasserhaltige Reinigungs- und Körperpflegemittel mit biozider Wirkung |
| DE102015000813A1 (de) | 2015-01-21 | 2016-07-21 | Smart Material Printing B.V. | Verfahren zur Vernichtung von Medikamenten und Giftstoffen und ihren Metaboliten mithilfe von Polyoxometallat-Mikro-und/oder -Nanopartikeln |
| WO2016116259A1 (de) | 2015-01-21 | 2016-07-28 | Smartmaterialprinting B.V. | Biozide ausrüstung von gegenständen und wasserhaltigen reinigungs- und körperpflegemitteln mit polyoxometallat-mikro und/oder - nanopartikeln |
| WO2019214841A1 (de) | 2018-05-07 | 2019-11-14 | Smart Material Printing B.V. | Selektive verwendung von polyoxometallaten gegen den befall von eukaryotenkulturen, virenkulturen und mikroorganismenpopulationen durch mollicuten sowie selektiv mollicutenhemmende und -abtötende polyoxometallathaltige stoffe und verfahren |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0182317A2 (en) * | 1984-11-20 | 1986-05-28 | Nippon Kayaku Kabushiki Kaisha | Antineoplastic agent |
| JPS63107959A (ja) * | 1985-11-15 | 1988-05-12 | Nippon Kayaku Co Ltd | 新規セレン化合物 |
| JPH01102023A (ja) * | 1987-10-16 | 1989-04-19 | Nippon Kayaku Co Ltd | 抗腫瘍剤 |
| JPH0228190A (ja) * | 1988-07-15 | 1990-01-30 | Tsumura & Co | 新規な亜セレン酸白金錯体および該錯体を有効成分とする抗腫瘍剤 |
| US6911470B1 (en) * | 1988-09-22 | 2005-06-28 | Raymond F. Schinazi | Polyoxometalate compounds as antiviral agents |
| JPH02134362A (ja) * | 1988-11-16 | 1990-05-23 | Nippon Kayaku Co Ltd | 新規セレン化合物 |
| US5302248A (en) * | 1992-08-28 | 1994-04-12 | The United States Of America As Represented By The Secretary Of Agriculture | Delignification of wood pulp by vanadium-substituted polyoxometalates |
| JPH11140067A (ja) * | 1997-10-20 | 1999-05-25 | Oxis Isle Of Man Ltd | 新規有機セレン化合物のプロ酸化剤としての使用、並びにそれらの製造法、医薬組成物及びその応用 |
| DE19751637A1 (de) * | 1997-10-30 | 1999-05-06 | Alexander Dr Manhart | Arzneimittel zur Tumortherapie |
| DE19825746A1 (de) * | 1998-06-09 | 1999-12-16 | Biosyn Arzneimittel Gmbh | Kombination von Selen-haltigen Verbindungen mit Zytostatika |
| CN1166651C (zh) * | 2001-06-08 | 2004-09-15 | 北京大学药学院 | 具有抗炎和抗肿瘤作用r-双或糖苯丙异硒唑取代化合物 |
| RU2185819C1 (ru) * | 2001-10-18 | 2002-07-27 | Дорофеенко Алла Ивановна | Средство, обладающее противоопухолевым действием |
| WO2004014832A2 (en) * | 2002-08-02 | 2004-02-19 | Vanetta S.P.A. | Redox process particularly for the production of menadione and use of polyoxometalates |
| US20060258697A1 (en) * | 2003-05-13 | 2006-11-16 | Rustum Youcef M | Method of augmenting the antitumor activity of anticancer agents |
| WO2004103355A1 (en) * | 2003-05-13 | 2004-12-02 | Health Research Inc. | Method for augmenting the antitumor activity of anti-cancer agents |
| US20050197399A1 (en) * | 2003-05-13 | 2005-09-08 | Marwan Fakih | Method of augmenting the antitumor activity of anticancer agents |
| CN101148445A (zh) * | 2007-01-26 | 2008-03-26 | 温州医学院 | 邻-二羟基黄酮-硒配合物制备方法及医学用途 |
-
2009
- 2009-04-23 MD MDA20090046A patent/MD4014C2/ro not_active IP Right Cessation
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4282C1 (ro) * | 2012-12-11 | 2014-11-30 | ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ | Utilizarea complecşilor polioxometalaţi cu atomi de seleniu centrali în calitate de compuşi cu activitate antitumorală |
| DE102015000814A1 (de) | 2015-01-21 | 2016-07-21 | Smart Material Printing B.V. | Biozide Ausrüstung von Gegenständen mit Polyoxometallat-Mikro- und/oder -Nanopartikeln |
| DE102015000812A1 (de) | 2015-01-21 | 2016-07-21 | Smart Material Printing B.V. | Wasserhaltige Reinigungs- und Körperpflegemittel mit biozider Wirkung |
| DE102015000813A1 (de) | 2015-01-21 | 2016-07-21 | Smart Material Printing B.V. | Verfahren zur Vernichtung von Medikamenten und Giftstoffen und ihren Metaboliten mithilfe von Polyoxometallat-Mikro-und/oder -Nanopartikeln |
| WO2016116259A1 (de) | 2015-01-21 | 2016-07-28 | Smartmaterialprinting B.V. | Biozide ausrüstung von gegenständen und wasserhaltigen reinigungs- und körperpflegemitteln mit polyoxometallat-mikro und/oder - nanopartikeln |
| WO2019214841A1 (de) | 2018-05-07 | 2019-11-14 | Smart Material Printing B.V. | Selektive verwendung von polyoxometallaten gegen den befall von eukaryotenkulturen, virenkulturen und mikroorganismenpopulationen durch mollicuten sowie selektiv mollicutenhemmende und -abtötende polyoxometallathaltige stoffe und verfahren |
Also Published As
| Publication number | Publication date |
|---|---|
| MD4014C2 (ro) | 2010-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |