MD4014C2 - Полиоксометаллатные комплексы обладающие противоопухолевой активностью - Google Patents

Полиоксометаллатные комплексы обладающие противоопухолевой активностью Download PDF

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Publication number
MD4014C2
MD4014C2 MDA20090046A MD20090046A MD4014C2 MD 4014 C2 MD4014 C2 MD 4014C2 MD A20090046 A MDA20090046 A MD A20090046A MD 20090046 A MD20090046 A MD 20090046A MD 4014 C2 MD4014 C2 MD 4014C2
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MD
Moldova
Prior art keywords
antitumor activity
synthesis
complex compounds
polyoxometalate
polyoxometalate complex
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Application number
MDA20090046A
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English (en)
Romanian (ro)
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MD4014B1 (en
Inventor
Татьяна ГУЦУЛ
Анатол ДИМОГЛО
Максим СОКОЛОВ
Севал КОРКМАЗ
Original Assignee
Татьяна ГУЦУЛ
Димогло Анатолий
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Application filed by Татьяна ГУЦУЛ, Димогло Анатолий filed Critical Татьяна ГУЦУЛ
Priority to MDA20090046A priority Critical patent/MD4014C2/ru
Publication of MD4014B1 publication Critical patent/MD4014B1/xx
Publication of MD4014C2 publication Critical patent/MD4014C2/ru

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Abstract

Изобретение относится к синтезу полиоксометаллатных комплексных соединений обладающих противоопухолевой активностью.Сущность изобретения заключается в синтезе полиоксометаллатных комплексных соединений, формулы:[N(CH3)4]5+n[Se2W19-nV3+nO71]·mH2O, где n = 0 или 2, m = 12 или 17, где атомы селена (IV) являются центральными.Результат изобретения состоит в синтезе полиоксометаллатных комплексных соединений обладающих 85…92% ингибирующим эффектом опухолевых клеток при концентрации 10…100 µМ.
MDA20090046A 2009-04-23 2009-04-23 Полиоксометаллатные комплексы обладающие противоопухолевой активностью MD4014C2 (ru)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20090046A MD4014C2 (ru) 2009-04-23 2009-04-23 Полиоксометаллатные комплексы обладающие противоопухолевой активностью

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20090046A MD4014C2 (ru) 2009-04-23 2009-04-23 Полиоксометаллатные комплексы обладающие противоопухолевой активностью

Publications (2)

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MD4014B1 MD4014B1 (en) 2010-02-26
MD4014C2 true MD4014C2 (ru) 2010-09-30

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MDA20090046A MD4014C2 (ru) 2009-04-23 2009-04-23 Полиоксометаллатные комплексы обладающие противоопухолевой активностью

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4282C1 (ru) * 2012-12-11 2014-11-30 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Использование полиоксометаллатных комплексов с центральными атомами селена в качестве соединений обладающих противоопухолевой активностью
EP3247210A1 (de) 2015-01-21 2017-11-29 Smartmaterialprinting B.V. Biozide ausrüstung von gegenständen und wasserhaltigen reinigungs- und körperpflegemitteln mit polyoxometallat-mikro und/oder - nanopartikeln
DE102015000813A1 (de) 2015-01-21 2016-07-21 Smart Material Printing B.V. Verfahren zur Vernichtung von Medikamenten und Giftstoffen und ihren Metaboliten mithilfe von Polyoxometallat-Mikro-und/oder -Nanopartikeln
DE102015000814A1 (de) 2015-01-21 2016-07-21 Smart Material Printing B.V. Biozide Ausrüstung von Gegenständen mit Polyoxometallat-Mikro- und/oder -Nanopartikeln
DE102015000812A1 (de) 2015-01-21 2016-07-21 Smart Material Printing B.V. Wasserhaltige Reinigungs- und Körperpflegemittel mit biozider Wirkung
DE102018003906A1 (de) 2018-05-07 2019-11-07 Smart Material Printing Verwendung von Polyoxometallaten gegen den Befall von Eukaryotenkulturen, Virenkulturen und Mikroorganismenpopulationen durch Mollicuten sowie mollicutenhemmende und -abtötende polyoxometallathaltige Stoffe und Verfahren

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* Cited by examiner, † Cited by third party
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JPS61267514A (ja) * 1984-11-20 1986-11-27 Nippon Kayaku Co Ltd 抗腫瘍剤
JPS63107959A (ja) * 1985-11-15 1988-05-12 Nippon Kayaku Co Ltd 新規セレン化合物
JPH01102023A (ja) * 1987-10-16 1989-04-19 Nippon Kayaku Co Ltd 抗腫瘍剤
JPH0228190A (ja) * 1988-07-15 1990-01-30 Tsumura & Co 新規な亜セレン酸白金錯体および該錯体を有効成分とする抗腫瘍剤
US6911470B1 (en) * 1988-09-22 2005-06-28 Raymond F. Schinazi Polyoxometalate compounds as antiviral agents
JPH02134362A (ja) * 1988-11-16 1990-05-23 Nippon Kayaku Co Ltd 新規セレン化合物
WO1994005849A1 (en) * 1992-08-28 1994-03-17 THE UNITED STATES OF AMERICA as represented by THE SECRETARY, U.S. DEPARTMENT OF AGRICULTURE Oxidative bleaching of wood pulp by vanadium-substituted polyoxometalates
JPH11140067A (ja) * 1997-10-20 1999-05-25 Oxis Isle Of Man Ltd 新規有機セレン化合物のプロ酸化剤としての使用、並びにそれらの製造法、医薬組成物及びその応用
DE19751637A1 (de) * 1997-10-30 1999-05-06 Alexander Dr Manhart Arzneimittel zur Tumortherapie
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GB2417685A (en) * 2003-05-13 2006-03-08 Health Research Inc Method for augmenting the antitumor activity of anti-cancer agents
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