MD940244A - Derivaţi noi ai tetrazolului, procedeu de obţinere a lor şi compoziţie farmaceutică pe baza lor - Google Patents
Derivaţi noi ai tetrazolului, procedeu de obţinere a lor şi compoziţie farmaceutică pe baza lorInfo
- Publication number
- MD940244A MD940244A MD94-0244A MD940244A MD940244A MD 940244 A MD940244 A MD 940244A MD 940244 A MD940244 A MD 940244A MD 940244 A MD940244 A MD 940244A
- Authority
- MD
- Moldova
- Prior art keywords
- obtaining
- new
- tetrazole
- base
- pharmaceutical composition
- Prior art date
Links
- 150000003536 tetrazoles Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 206010020772 Hypertension Diseases 0.000 abstract 2
- 230000002860 competitive effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- JYPVVOOBQVVUQV-CGHBYZBKSA-N angiotensinamide Chemical compound C([C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(N)=O)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=C(O)C=C1 JYPVVOOBQVVUQV-CGHBYZBKSA-N 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052949 galena Inorganic materials 0.000 abstract 1
- XCAUINMIESBTBL-UHFFFAOYSA-N lead(ii) sulfide Chemical compound [Pb]=S XCAUINMIESBTBL-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Invenţia se referă la la derivaţii noi, terapeutic valoroşi, ai tetrazolului, care pot fi folosiţi pentru tratarea hipertensiunii arteriale, provocate de angiotenzină II.Scopul invenţiei constă în crearea antagoniştilor pur competitivi, care nu formează nici un fel de metaboliţi competitivi.Obiectul invenţiei sunt derivaţii noi ai tetrazolului cu formula:precum şi sărurile lor farmaceutice utilizabile.Se descrie procedeul de obţinere a compuşilor indicaţi. Comuşii noi, solitar sau amestic cu alte substanţe active în formă de compoziţii galenice obişnuite, îşi pot găsi aplicare în calitate de remedii medicinale pentru tratarea hipertensiunii arteriale şi a altor boli cardiovasculare.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MD94-0244A MD940244A (ro) | 1994-07-12 | 1994-07-12 | Derivaţi noi ai tetrazolului, procedeu de obţinere a lor şi compoziţie farmaceutică pe baza lor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MD94-0244A MD940244A (ro) | 1994-07-12 | 1994-07-12 | Derivaţi noi ai tetrazolului, procedeu de obţinere a lor şi compoziţie farmaceutică pe baza lor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD940244A true MD940244A (ro) | 1996-01-31 |
Family
ID=62142652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0244A MD940244A (ro) | 1994-07-12 | 1994-07-12 | Derivaţi noi ai tetrazolului, procedeu de obţinere a lor şi compoziţie farmaceutică pe baza lor |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD940244A (ro) |
-
1994
- 1994-07-12 MD MD94-0244A patent/MD940244A/ro unknown
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