MD984B1 - Tabletă de ranitidină avînd acoperire şi procedeu de obţinere a acestei acoperiri - Google Patents

Tabletă de ranitidină avînd acoperire şi procedeu de obţinere a acestei acoperiri

Info

Publication number
MD984B1
MD984B1 MD97-0008A MD970008A MD984B1 MD 984 B1 MD984 B1 MD 984B1 MD 970008 A MD970008 A MD 970008A MD 984 B1 MD984 B1 MD 984B1
Authority
MD
Moldova
Prior art keywords
coating
tablet
ranitidine
obtaining
aqeous
Prior art date
Application number
MD97-0008A
Other languages
English (en)
Russian (ru)
Inventor
Bols PEDERSEN Soren
Erik GEBHARDT-HANSEN Knud
Helle Kann
Original Assignee
A/S Gea Farmaceutisk Fabrik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A/S Gea Farmaceutisk Fabrik filed Critical A/S Gea Farmaceutisk Fabrik
Publication of MD984B1 publication Critical patent/MD984B1/ro

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Invenţia se referă la farmacologie, în special la acoperirea unor tablete farmaceutice pentru administrarea orală şi la procedeele de obţinere a acestor acoperiri.Conform invenţiei acoperirea tabletei de ranitidină conţinând cel puţin 30% de hidroclorură de ranitidină include hi hidroclorură de ranitidină include hidroxipropilmetilceluloză şi etilceluloză, totodată raportul lor de masă este de la 10:1 până la 1:2.Acoperirea este depusă prin pulverizarea soluţiei care conţine componente dizolvate în 72,5...82,5% de soluţie apoasă de alcool în procesul trecerii tabletei prin curentul de aer uscat la temperatura evaporării soluţiei apoase de alcool.Rezultatul tehnic al invenţiei constă în prevenirea penetrării vaporilor apoşi şi a hidroclorurii de ranitidină prin acoperirea tabletei.
MD97-0008A 1994-04-22 1995-04-19 Tabletă de ranitidină avînd acoperire şi procedeu de obţinere a acestei acoperiri MD984B1 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK046894A DK171127B1 (da) 1994-04-22 1994-04-22 Ranitidintablet med et hydroxypropylmethylcelluloseholdigt overtræk samt fremgangsmåde til at tilvejebringe dette overtræk
PCT/DK1995/000163 WO1995028918A1 (en) 1994-04-22 1995-04-19 A ranitidine tablet having a hydroxypropylmethylcellulose containing coating and a method for producing said coating

Publications (1)

Publication Number Publication Date
MD984B1 true MD984B1 (ro) 1998-06-30

Family

ID=8093891

Family Applications (1)

Application Number Title Priority Date Filing Date
MD97-0008A MD984B1 (ro) 1994-04-22 1995-04-19 Tabletă de ranitidină avînd acoperire şi procedeu de obţinere a acestei acoperiri

Country Status (26)

Country Link
US (1) US5741507A (ro)
EP (1) EP0794768A1 (ro)
JP (1) JPH09512023A (ro)
KR (1) KR970702031A (ro)
CN (1) CN1146148A (ro)
AU (1) AU690680B2 (ro)
BG (1) BG100992A (ro)
BR (1) BR9507486A (ro)
CA (1) CA2187323A1 (ro)
CZ (1) CZ283645B6 (ro)
DE (1) DE794768T1 (ro)
DK (1) DK171127B1 (ro)
EE (1) EE03248B1 (ro)
ES (1) ES2106696T1 (ro)
FI (1) FI964238A7 (ro)
GR (1) GR970300040T1 (ro)
HU (1) HUT75962A (ro)
IS (1) IS4375A (ro)
LV (1) LV11591B (ro)
MD (1) MD984B1 (ro)
NO (1) NO964198L (ro)
NZ (1) NZ284792A (ro)
PL (1) PL316965A1 (ro)
RU (1) RU2117476C1 (ro)
SK (1) SK134896A3 (ro)
WO (1) WO1995028918A1 (ro)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW464502B (en) * 1996-03-12 2001-11-21 Shiseido Co Ltd W/O type emulsified composition and the method of making the same, and W/O type emulsified cosmetic
US6306164B1 (en) 1997-09-05 2001-10-23 C. R. Bard, Inc. Short body endoprosthesis
RU2154469C2 (ru) * 1998-08-10 2000-08-20 Открытое акционерное общество фармацевтическая фирма "ЗДОРОВЬЕ" Способ получения таблеток ранитидина
IT1311915B1 (it) * 1999-04-12 2002-03-20 Pharmexcel S R L Compressa anidra di cloridrato di ranitidina con rivestimento a doppiostrato e sua composizione.
SE9903879D0 (sv) * 1999-10-28 1999-10-28 Ethical Pharmaceuticals Sweden Multipor food protection
RU2155035C1 (ru) * 2000-02-03 2000-08-27 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая противоязвенной активностью, и способ ее получения
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
KR100459770B1 (ko) * 2002-01-29 2004-12-04 전자부품연구원 실리카 미립자가 증착된 웨이퍼의 고밀화 방법
US20050152932A1 (en) * 2003-06-12 2005-07-14 Valery Normand Non-crystalline perfume or flavor delivery system
US7641362B2 (en) * 2007-04-30 2010-01-05 Hewlett-Packard Development Company, L.P. Electronic device lighting system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90245A (en) * 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it
US4880636A (en) * 1988-05-13 1989-11-14 Franz Robert M Film coated tablet of ranitidine HCl
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
CA2146999A1 (en) * 1992-10-16 1994-04-28 Stephen John Douglas Taste-masking compositions of ranitidine

Also Published As

Publication number Publication date
NO964198D0 (no) 1996-10-03
HUT75962A (en) 1997-05-28
AU2343095A (en) 1995-11-16
LV11591B (en) 1997-04-20
CZ308696A3 (en) 1997-04-16
HU9602689D0 (en) 1996-11-28
US5741507A (en) 1998-04-21
RU2117476C1 (ru) 1998-08-20
CA2187323A1 (en) 1995-11-02
EE03248B1 (et) 2000-02-15
SK134896A3 (en) 1997-05-07
FI964238L (fi) 1996-10-21
EP0794768A1 (en) 1997-09-17
MX9604858A (es) 1998-05-31
DK171127B1 (da) 1996-06-24
BG100992A (en) 1997-08-29
NZ284792A (en) 1997-03-24
IS4375A (is) 1996-10-07
LV11591A (lv) 1996-12-20
AU690680B2 (en) 1998-04-30
FI964238A0 (fi) 1996-10-21
PL316965A1 (en) 1997-03-03
DK46894A (da) 1995-10-23
GR970300040T1 (en) 1997-11-28
NO964198L (no) 1996-10-03
BR9507486A (pt) 1997-08-12
CN1146148A (zh) 1997-03-26
JPH09512023A (ja) 1997-12-02
KR970702031A (ko) 1997-05-13
DE794768T1 (de) 1998-01-15
WO1995028918A1 (en) 1995-11-02
CZ283645B6 (cs) 1998-05-13
FI964238A7 (fi) 1996-10-21
ES2106696T1 (es) 1997-11-16

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