ME01056B - Upotreba estradiolvalerata i dienogesta za oralno liječenje disfunkcionalnog uterinog krvarenja u kontracepcijskom metodu - Google Patents
Upotreba estradiolvalerata i dienogesta za oralno liječenje disfunkcionalnog uterinog krvarenja u kontracepcijskom metoduInfo
- Publication number
- ME01056B ME01056B MEP-2009-171A MEP17109A ME01056B ME 01056 B ME01056 B ME 01056B ME P17109 A MEP17109 A ME P17109A ME 01056 B ME01056 B ME 01056B
- Authority
- ME
- Montenegro
- Prior art keywords
- daily dose
- dienogest
- units
- estradiol valerate
- estradiolvalerate
- Prior art date
Links
- RSEPBGGWRJCQGY-RBRWEJTLSA-N Estradiol valerate Chemical compound C1CC2=CC(O)=CC=C2[C@@H]2[C@@H]1[C@@H]1CC[C@H](OC(=O)CCCC)[C@@]1(C)CC2 RSEPBGGWRJCQGY-RBRWEJTLSA-N 0.000 title claims 6
- 229960004766 estradiol valerate Drugs 0.000 title claims 6
- AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 title claims 4
- 229960003309 dienogest Drugs 0.000 title claims 4
- 206010013908 Dysfunctional uterine bleeding Diseases 0.000 title claims 2
- 206010027514 Metrorrhagia Diseases 0.000 title claims 2
- 239000003433 contraceptive agent Substances 0.000 title 1
- 230000002254 contraceptive effect Effects 0.000 title 1
- 208000032843 Hemorrhage Diseases 0.000 claims 1
- 230000000740 bleeding effect Effects 0.000 claims 1
- 229940083544 estradiol 2 mg Drugs 0.000 claims 1
- 230000002175 menstrual effect Effects 0.000 claims 1
- 229940068196 placebo Drugs 0.000 claims 1
- 239000000902 placebo Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Claims (1)
1. Primena estradiolvalerata u kombinaciji sa 17α-cijanometil-17-β-hidroksiestra-4,9-dien-3- on (dienogest), naznačena time da sadržava prvu fazu sa 2 jedinice dnevne doze estradiolvalerata do 3 mg, drugu fazu sa 2 grupe jedinice dnevne doze, pri čemu prva grupa sadržava 5 jedinica dnevne doze kombinacije 2 mg estradiolvalerata i 2 mg dienogesta, i druga grupa sadržava 17 jedinica dnevne doze kombinacije 2 mg estradiolvalerata i 3 mg dienogesta, treću fazu sa 2 jedinice dnevne doze sa l mg estradiolvalerata i jednu dodatnu fazu sa 2 jedinice dnevne doze farmaceutski neškodljivog placeba za izradu višefaznog kombinovanog preparata sa ukupnim brojem od 28 jedinica dnevne doze za oralnu terapiju disfunkcionalnog uterinog krvarenja, gde se podrazumeva menstrualna krvarenje duže od 7 dana, zajedno sa oralnom kontracepcijom.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05022324A EP1787649B1 (de) | 2005-10-13 | 2005-10-13 | Verwendung von Estradiolvalerat in Kombination mit Dienogest zur oralen Therapie der dysfunktionellen uterinen Blutung in Einheit mit einer oralen Kontrazeption |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME01056B true ME01056B (me) | 2012-10-20 |
Family
ID=35811580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2009-171A ME01056B (me) | 2005-10-13 | 2005-10-13 | Upotreba estradiolvalerata i dienogesta za oralno liječenje disfunkcionalnog uterinog krvarenja u kontracepcijskom metodu |
Country Status (22)
| Country | Link |
|---|---|
| EP (2) | EP1787649B1 (me) |
| JP (2) | JP5735200B2 (me) |
| KR (2) | KR101218872B1 (me) |
| CN (1) | CN101312733A (me) |
| AR (1) | AR056694A1 (me) |
| AT (2) | ATE424828T1 (me) |
| CA (1) | CA2623024C (me) |
| CL (1) | CL2011000283A1 (me) |
| CY (2) | CY1110321T1 (me) |
| DE (2) | DE502005006837D1 (me) |
| DK (2) | DK1787649T3 (me) |
| DO (1) | DOP2006000221A (me) |
| ES (2) | ES2322479T3 (me) |
| HR (1) | HRP20090256T1 (me) |
| ME (1) | ME01056B (me) |
| PE (2) | PE20100090A1 (me) |
| PL (2) | PL1787649T3 (me) |
| PT (2) | PT1787649E (me) |
| SI (2) | SI1787649T1 (me) |
| TW (2) | TWI328453B (me) |
| UY (1) | UY29861A1 (me) |
| WO (1) | WO2007042296A1 (me) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004019743B4 (de) | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| DE502005006837D1 (de) * | 2005-10-13 | 2009-04-23 | Bayer Schering Pharma Ag | Verwendung von Estradiolvalerat in Kombination mit Dienogest zur oralen Therapie der dysfunktionellen uterinen Blutung in Einheit mit einer oralen Kontrazeption |
| US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4429374C1 (de) * | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| DE19540253C2 (de) * | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
| AU4043597A (en) * | 1996-07-26 | 1998-02-20 | American Home Products Corporation | Biphasic contraceptive method and kit comprising a combination of a progestin and estrogen |
| US6251956B1 (en) | 1998-08-20 | 2001-06-26 | Ortho Pharmaceutical Corporation | Combination progestin oral contraceptive regimen |
| EP1462106A1 (en) * | 2003-03-28 | 2004-09-29 | Pantarhei Bioscience B.V. | Pharmaceutical compositions and kits comprising 17-beta-estradiol and a progesteron for the treatment of gynecological disorders |
| DE102004019743B4 (de) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| DE502005006837D1 (de) * | 2005-10-13 | 2009-04-23 | Bayer Schering Pharma Ag | Verwendung von Estradiolvalerat in Kombination mit Dienogest zur oralen Therapie der dysfunktionellen uterinen Blutung in Einheit mit einer oralen Kontrazeption |
-
2005
- 2005-10-13 DE DE502005006837T patent/DE502005006837D1/de not_active Expired - Lifetime
- 2005-10-13 ES ES05022324T patent/ES2322479T3/es not_active Expired - Lifetime
- 2005-10-13 ME MEP-2009-171A patent/ME01056B/me unknown
- 2005-10-13 SI SI200530672T patent/SI1787649T1/sl unknown
- 2005-10-13 PT PT05022324T patent/PT1787649E/pt unknown
- 2005-10-13 AT AT05022324T patent/ATE424828T1/de active
- 2005-10-13 PL PL05022324T patent/PL1787649T3/pl unknown
- 2005-10-13 EP EP05022324A patent/EP1787649B1/de not_active Revoked
- 2005-10-13 DK DK05022324T patent/DK1787649T3/da active
-
2006
- 2006-10-12 EP EP06806225A patent/EP1933843B1/de active Active
- 2006-10-12 CN CNA2006800381810A patent/CN101312733A/zh active Pending
- 2006-10-12 PL PL06806225T patent/PL1933843T3/pl unknown
- 2006-10-12 DE DE502006008853T patent/DE502006008853D1/de active Active
- 2006-10-12 JP JP2008534936A patent/JP5735200B2/ja active Active
- 2006-10-12 KR KR1020107014574A patent/KR101218872B1/ko active Active
- 2006-10-12 PE PE2009001256A patent/PE20100090A1/es not_active Application Discontinuation
- 2006-10-12 DK DK06806225.6T patent/DK1933843T3/da active
- 2006-10-12 PE PE2006001241A patent/PE20070555A1/es not_active Application Discontinuation
- 2006-10-12 SI SI200630991T patent/SI1933843T1/sl unknown
- 2006-10-12 ES ES06806225T patent/ES2360302T3/es active Active
- 2006-10-12 TW TW095137564A patent/TWI328453B/zh active
- 2006-10-12 AT AT06806225T patent/ATE497387T1/de active
- 2006-10-12 WO PCT/EP2006/009867 patent/WO2007042296A1/de not_active Ceased
- 2006-10-12 PT PT06806225T patent/PT1933843E/pt unknown
- 2006-10-12 KR KR1020087011203A patent/KR20080065651A/ko not_active Ceased
- 2006-10-12 CA CA2623024A patent/CA2623024C/en active Active
- 2006-10-13 AR ARP060104489A patent/AR056694A1/es not_active Application Discontinuation
- 2006-10-13 UY UY29861A patent/UY29861A1/es not_active Application Discontinuation
- 2006-10-13 DO DO2006000221A patent/DOP2006000221A/es unknown
-
2007
- 2007-01-09 TW TW096100872A patent/TW200829255A/zh unknown
-
2009
- 2009-05-05 HR HR20090256T patent/HRP20090256T1/xx unknown
- 2009-06-11 CY CY20091100621T patent/CY1110321T1/el unknown
-
2011
- 2011-02-10 CL CL2011000283A patent/CL2011000283A1/es unknown
- 2011-05-02 CY CY20111100422T patent/CY1111406T1/el unknown
-
2012
- 2012-11-19 JP JP2012253067A patent/JP2013047269A/ja active Pending
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