MX2013013256A - Proceso para la preparacion de beta-santalol. - Google Patents

Proceso para la preparacion de beta-santalol.

Info

Publication number
MX2013013256A
MX2013013256A MX2013013256A MX2013013256A MX2013013256A MX 2013013256 A MX2013013256 A MX 2013013256A MX 2013013256 A MX2013013256 A MX 2013013256A MX 2013013256 A MX2013013256 A MX 2013013256A MX 2013013256 A MX2013013256 A MX 2013013256A
Authority
MX
Mexico
Prior art keywords
santalol
preparation
alkyl
compound
beta
Prior art date
Application number
MX2013013256A
Other languages
English (en)
Inventor
Anthony A Birkbeck
Original Assignee
Firmenich & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie filed Critical Firmenich & Cie
Publication of MX2013013256A publication Critical patent/MX2013013256A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/26—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/297—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/095—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of organic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/283—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/14—Acetic acid esters of monohydroxylic compounds
    • C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/24—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Fats And Perfumes (AREA)

Abstract

La presente invención se relaciona con un proceso para la preparación de un compuesto de la fórmula (I) en la forma de cualquiera de sus estereoisómeros o mezclas de los mismos, y en donde R representa un grupo C2-C10 de la fórmula CORa, en donde Ra es un grupo alquilo o alquenilo que comprende opcionalmente uno o dos grupos funcionales o es un grupo fenilo o bencilo opcionalmente sustituido por uno a tres grupos alquilo, alcoxilo, carboxilo, acilo, amino o nitro o átomos de halógeno. La invención también se relaciona con el uso del compuesto (I) para la síntesis de ß-santalol o de sus derivados.
MX2013013256A 2011-06-30 2012-06-28 Proceso para la preparacion de beta-santalol. MX2013013256A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161503224P 2011-06-30 2011-06-30
EP11172037 2011-06-30
PCT/EP2012/062614 WO2013001026A1 (en) 2011-06-30 2012-06-28 Process for the preparation of beta-santalol

Publications (1)

Publication Number Publication Date
MX2013013256A true MX2013013256A (es) 2013-12-16

Family

ID=44584802

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013013256A MX2013013256A (es) 2011-06-30 2012-06-28 Proceso para la preparacion de beta-santalol.

Country Status (9)

Country Link
US (1) US9056826B2 (es)
EP (1) EP2726447B1 (es)
JP (1) JP5901757B2 (es)
CN (1) CN103596910B (es)
BR (1) BR112013029840A2 (es)
ES (1) ES2547922T3 (es)
IL (1) IL230125A (es)
MX (1) MX2013013256A (es)
WO (1) WO2013001026A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6921127B2 (ja) * 2016-06-03 2021-08-18 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ ポリサントール型化合物の製造方法
CN108707073A (zh) * 2018-04-18 2018-10-26 帕潘纳(北京)科技有限公司 一种亚丙烯双乙酯的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679756A (en) 1969-05-21 1972-07-25 Procter & Gamble Process for preparing {62 -santalol from 3-methylnorcamphor
US3662008A (en) 1969-05-21 1972-05-09 Procter & Gamble Process for preparing beta-santalol from 3-methylnorcamphor
US4223167A (en) * 1978-02-14 1980-09-16 Fritzsche Dodge & Olcott Inc. Processes for preparing β-santalol, β-santalene dihydro-β-santalol and related compounds
DE2843838A1 (de) 1978-10-07 1980-04-24 Basf Ag Bicyclische verbindungen, verfahren zu deren herstellung und deren verwendung
JPS5738730A (en) * 1980-08-14 1982-03-03 Kuraray Co Ltd Cis-pentene derivative and its preparation
DE10348062A1 (de) 2003-10-16 2005-05-19 Symrise Gmbh & Co. Kg Kurzkettige Enolester als Riechstoff-Prekursoren
JP5376939B2 (ja) * 2005-05-11 2013-12-25 フイルメニツヒ ソシエテ アノニム 触媒スクリャービン反応
ES2399484T3 (es) 2007-03-07 2013-04-01 Ube Industries, Ltd. Procedimiento de mantenimiento de la calidad de 2-metil-3-(3,4-metilendioxifenil)propanal y procedimiento para producir el mismo
US8003838B2 (en) 2007-04-03 2011-08-23 Firmenich Sa 1,4-hydrogenation of dienes with Ru complexes
ES2401986T3 (es) 2008-05-20 2013-04-26 Firmenich Sa Intermedios de preparación de beta-santalol y derivados del mismo

Also Published As

Publication number Publication date
JP5901757B2 (ja) 2016-04-13
EP2726447B1 (en) 2015-08-12
EP2726447A1 (en) 2014-05-07
US20140213818A1 (en) 2014-07-31
ES2547922T3 (es) 2015-10-09
IL230125A (en) 2016-06-30
CN103596910B (zh) 2015-11-25
US9056826B2 (en) 2015-06-16
JP2014522825A (ja) 2014-09-08
CN103596910A (zh) 2014-02-19
WO2013001026A1 (en) 2013-01-03
BR112013029840A2 (pt) 2016-12-06

Similar Documents

Publication Publication Date Title
MX377552B (es) Proceso para preparar un compuesto antiviral de formula i.
EA201391239A1 (ru) Пирроло[2,3-d]пиримидиновые производные в качестве ингибиторов тропомиозин-связанных киназ
IN2014CN04530A (es)
EA201291409A1 (ru) Производные индолизина, способ их получения и их терапевтическое применение
MY172924A (en) Neprilysin inhibitors
BR112013031405A2 (pt) piridopirazinas substituídas como novos inibidores de syk
DOP2014000036A (es) Compuestos de piridazinona y su uso como inhibidores daao
CR20140294A (es) Derivados de dihidro-benzo-oxazina y dihidro-pirido-oxazina
BR112015012425A2 (pt) composto, composição farmacêutica, método e medicamento para o tratamento de doenças medicadas pela proteína parp-1 e uso do composto
AU2012213775A8 (en) 7-azaindole derivatives
BR112015004529A2 (pt) alcóxi pirazóis como ativadores de guanilato ciclase solúvel
MX2013015436A (es) Compuestos de eter amido-piridilico y composiciones y su uso contra parasitos.
MX364207B (es) Inhibidores de agrecanasa.
CO6751286A2 (es) Síntesis de derivados de 2-carboxamida-cicloamino-urea
JO3196B1 (ar) عملية تحضير ملح ل – ارجينين البيريندوبريل
ECSP13012548A (es) Inhibidores de oxadiazol de la producción de leucotrienos.
IN2014MN00850A (es)
MX2012007253A (es) Derivados triciclicos y sus usos y composiciones farmaceuticas.
CY1115983T1 (el) Συνθεση toy aliskiren
CY1117011T1 (el) Παραγωγα αζολιου
MX2013013256A (es) Proceso para la preparacion de beta-santalol.
IN2012DN02698A (es)
CR20150160A (es) Derivados de macrólidos, su preparación y su uso terapéutico
CR20120109A (es) Nuevos derivados dihidro-oxazolobenzodiazepinonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen
MX2013013266A (es) Proceso para la preparacion de beta-santalol.

Legal Events

Date Code Title Description
FG Grant or registration