MX2020005448A - Sonda de recoleccion minimamente invasiva y metodos para el uso de esta. - Google Patents

Sonda de recoleccion minimamente invasiva y metodos para el uso de esta.

Info

Publication number
MX2020005448A
MX2020005448A MX2020005448A MX2020005448A MX2020005448A MX 2020005448 A MX2020005448 A MX 2020005448A MX 2020005448 A MX2020005448 A MX 2020005448A MX 2020005448 A MX2020005448 A MX 2020005448A MX 2020005448 A MX2020005448 A MX 2020005448A
Authority
MX
Mexico
Prior art keywords
minimally invasive
methods
invasive collection
collection probe
devices
Prior art date
Application number
MX2020005448A
Other languages
English (en)
Inventor
Livia Schiavinato Eberlin
Thomas Milner
Jialing Zhang
Nitesh Katta
Noah Giese
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of MX2020005448A publication Critical patent/MX2020005448A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4055—Concentrating samples by solubility techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/313—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
    • A61B1/3132—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes for laparoscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/04—Endoscopic instruments, e.g. catheter-type instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/30—Surgical robots
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404—Capillaries used for transferring samples or ions
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0459—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/28—Surgical forceps
    • A61B17/29—Forceps for use in minimally invasive surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A61B2090/395—Visible markers with marking agent for marking skin or other tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3983—Reference marker arrangements for use with image guided surgery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Plasma & Fusion (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Robotics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Endoscopes (AREA)

Abstract

Se proporcionan métodos y dispositivos para evaluar muestras de tejido de una pluralidad de sitios de tejido en un sujeto usando análisis molecular; en ciertos aspectos, los dispositivos de las formas de realización permiten la recolección mínimamente invasiva de muestras de tejido líquido y la administración de las muestras para análisis de espectrometría de masas.
MX2020005448A 2017-11-27 2018-11-27 Sonda de recoleccion minimamente invasiva y metodos para el uso de esta. MX2020005448A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762591179P 2017-11-27 2017-11-27
US201862640385P 2018-03-08 2018-03-08
PCT/US2018/062625 WO2019104328A1 (en) 2017-11-27 2018-11-27 Minimally invasive collection probe and methods for the use thereof

Publications (1)

Publication Number Publication Date
MX2020005448A true MX2020005448A (es) 2020-08-27

Family

ID=66630809

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020005448A MX2020005448A (es) 2017-11-27 2018-11-27 Sonda de recoleccion minimamente invasiva y metodos para el uso de esta.

Country Status (11)

Country Link
US (2) US20200305723A1 (es)
EP (1) EP3717901A4 (es)
JP (1) JP2021504703A (es)
CN (1) CN111566481A (es)
AU (1) AU2018373391A1 (es)
BR (1) BR112020010416A2 (es)
CA (1) CA3083260A1 (es)
IL (1) IL274759A (es)
MX (1) MX2020005448A (es)
SG (1) SG11202004568UA (es)
WO (1) WO2019104328A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4357784A3 (en) 2016-09-02 2024-07-31 Board of Regents, The University of Texas System Collection probe and methods for the use thereof
WO2018227079A1 (en) * 2017-06-08 2018-12-13 Board Of Regents, The University Of Texas System Systems and methods for microarray droplet ionization analysis
JP2021504703A (ja) 2017-11-27 2021-02-15 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 低侵襲性収集プローブおよびその使用方法
US11219393B2 (en) 2018-07-12 2022-01-11 Trace Matters Scientific Llc Mass spectrometry system and method for analyzing biological samples
US12089932B2 (en) 2018-06-05 2024-09-17 Trace Matters Scientific Llc Apparatus, system, and method for transferring ions
BR112021014553A2 (pt) * 2019-01-25 2021-10-05 Board Of Regents, The University Of Texas System Aparelho e métodos para limpeza e/ou troca de dispositivos médicos
WO2021222154A1 (en) * 2020-04-27 2021-11-04 Board Of Regents, The University Of Texas System Detecting chemical compounds for forensic analysis
WO2021222515A1 (en) * 2020-04-29 2021-11-04 Ms Pen Technologies, Inc. Collecting and analyzing swab samples
US12121216B2 (en) * 2021-02-13 2024-10-22 Board Of Regents, The University Of Texas System Miniature hyperspectral imaging
CN113842210B (zh) * 2021-08-02 2024-10-22 应葵 椎骨肿瘤微波消融手术仿真方法及装置
CN115513037B (zh) * 2022-10-08 2025-09-26 南开大学 一种激光感应场致液滴电离装置
CN120267949B (zh) * 2025-06-09 2025-09-23 上海交通大学医学院附属仁济医院 一种可用于零射线心肌活检的活检钳引导导管

Family Cites Families (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989000829A1 (en) * 1987-07-23 1989-02-09 Terumo Kabushiki Kaisha Catheter tube
US5711816A (en) * 1990-07-06 1998-01-27 Advanced Technolgy Materials, Inc. Source reagent liquid delivery apparatus, and chemical vapor deposition system comprising same
US5119827A (en) 1990-09-05 1992-06-09 Board Of Regents, The University Of Texas System Mechanisms of antiestrogen resistance in breast cancer
US5100402A (en) 1990-10-05 1992-03-31 Megadyne Medical Products, Inc. Electrosurgical laparoscopic cauterization electrode
US5241990A (en) * 1992-07-10 1993-09-07 Inlet Medical, Inc. Irrigation/aspiration valve and probe for laparoscopy
US5470308A (en) 1992-08-12 1995-11-28 Vidamed, Inc. Medical probe with biopsy stylet
US5746720A (en) * 1995-10-18 1998-05-05 Stouder, Jr.; Albert E. Method and apparatus for insertion of a cannula and trocar
US5742050A (en) 1996-09-30 1998-04-21 Aviv Amirav Method and apparatus for sample introduction into a mass spectrometer for improving a sample analysis
US6297499B1 (en) 1997-07-17 2001-10-02 John B Fenn Method and apparatus for electrospray ionization
US6786884B1 (en) * 1999-10-29 2004-09-07 Bard Access Systems, Inc. Bolus tip design for a multi-lumen catheter
ATE386335T1 (de) 1999-10-29 2008-03-15 Mds Inc Through Its Mds Sciex Atmosphärendruckphotoionisation : ein neues ionisationsverfahren für flüssigchromatographie- massenspekrometrie
WO2002042733A2 (en) 2000-11-16 2002-05-30 Ciphergen Biosystems, Inc. Method for analyzing mass spectra
US6784439B2 (en) 2001-07-19 2004-08-31 Ut Battelle, Llc Thin-channel electrospray emitter
US20040014227A1 (en) * 2002-01-04 2004-01-22 Frederick Erik D. Apparatus, method and computer program product for automated high-throughput sampling and data acquisition
US6803566B2 (en) 2002-04-16 2004-10-12 Ut-Battelle, Llc Sampling probe for microarray read out using electrospray mass spectrometry
JP4095349B2 (ja) 2002-06-03 2008-06-04 ペンタックス株式会社 蛍光測定装置
US6677593B1 (en) 2002-08-28 2004-01-13 Ut-Battelle, Llc Planar flow-by electrode capacitive electrospray ion source
CA2433205A1 (en) 2003-03-18 2004-09-18 James Alexander Keenan Drug delivery, bodily fluid drainage, and biopsy device with enhanced ultrasonic visibility
US7684934B2 (en) 2003-06-06 2010-03-23 The United States Of America As Represented By The Department Of Health And Human Services Pattern recognition of whole cell mass spectra
US7335897B2 (en) 2004-03-30 2008-02-26 Purdue Research Foundation Method and system for desorption electrospray ionization
US7445603B2 (en) 2004-05-12 2008-11-04 Zkz Science Corp. Apparatus for removable distal internal cassette for in situ fixation and specimen processing with serial collection and storage of biopsy specimens
TW200626892A (en) 2004-09-14 2006-08-01 Metara Inc In-process mass spectrometry with sample multiplexing
US7295026B2 (en) 2005-06-03 2007-11-13 Ut-Battelle, Llc Automated position control of a surface array relative to a liquid microjunction surface sampler
US20060292607A1 (en) 2005-06-08 2006-12-28 Vanderbilt University Analysis of tissue samples surrounding malignancies
DE102005044307B4 (de) 2005-09-16 2008-04-17 Bruker Daltonik Gmbh Ionisierung desorbierter Moleküle
US7714276B2 (en) 2005-09-30 2010-05-11 New York University Methods for direct biomolecule identification by matrix-assisted laser desorption ionization (MALDI) mass spectrometry
DK1960014T3 (en) * 2005-12-14 2017-01-09 Stryker Corp Medical / surgical waste collection and disposal system
US7544933B2 (en) 2006-01-17 2009-06-09 Purdue Research Foundation Method and system for desorption atmospheric pressure chemical ionization
US7777181B2 (en) 2006-05-26 2010-08-17 Ionsense, Inc. High resolution sampling system for use with surface ionization technology
HU226837B1 (hu) 2006-05-31 2009-12-28 Semmelweis Egyetem Folyadéksugárral mûködõ deszorpciós ionizációs eljárás és eszköz
US7800056B2 (en) 2006-10-26 2010-09-21 Smiths Detection Montreal Inc. Document sampler and method of sampling a document
US20100176287A1 (en) 2006-11-23 2010-07-15 Koninklijke Philips Electronics N.V. Device for separation and maldi analysis of an analyte in a sample
US7847244B2 (en) 2006-12-28 2010-12-07 Purdue Research Foundation Enclosed desorption electrospray ionization
WO2008097831A1 (en) 2007-02-02 2008-08-14 Waters Investments Limited Device and method for analyzing a sample
US20080243141A1 (en) 2007-04-02 2008-10-02 Salvatore Privitera Surgical instrument with separate tool head and method of use
US8803080B2 (en) 2007-06-02 2014-08-12 Cerno Bioscience Llc Self calibration approach for mass spectrometry
CN101932727A (zh) 2008-01-03 2010-12-29 得克萨斯大学体系董事会 通过极光激酶a的荧光原位杂交非侵入性检测膀胱癌
US9213030B2 (en) 2008-01-28 2015-12-15 National University Of Singapore Lipid tumour profile
EP2249737B1 (en) * 2008-03-03 2020-07-01 Koninklijke Philips N.V. Biopsy guidance by electromagnetic tracking and photonic needle
KR20110014983A (ko) 2008-04-10 2011-02-14 더 유니버시티 오브 브리티시 콜롬비아 심장 동종이식 만성 거부반응 진단방법
US8207494B2 (en) 2008-05-01 2012-06-26 Indiana University Research And Technology Corporation Laser ablation flowing atmospheric-pressure afterglow for ambient mass spectrometry
US8084735B2 (en) 2008-09-25 2011-12-27 Ut-Battelle, Llc Pulsed voltage electrospray ion source and method for preventing analyte electrolysis
WO2010039675A1 (en) 2008-09-30 2010-04-08 Prosolia, Inc. Method and apparatus for embedded heater for desorption and ionization of analytes
EP3805758A1 (en) 2008-12-19 2021-04-14 Medirista Biotechnologies AB Oxidized cardiolipin as a novel pro-inflammatory factor
US20100224013A1 (en) 2009-03-05 2010-09-09 Van Berkel Gary J Method and system for formation and withdrawal of a sample from a surface to be analyzed
WO2010114976A1 (en) 2009-04-01 2010-10-07 Prosolia, Inc. Method and system for surface sampling
US9500572B2 (en) 2009-04-30 2016-11-22 Purdue Research Foundation Sample dispenser including an internal standard and methods of use thereof
EP3633710B1 (en) 2009-04-30 2022-12-07 Purdue Research Foundation Ion generation using wetted porous material
US8704167B2 (en) 2009-04-30 2014-04-22 Purdue Research Foundation Mass spectrometry analysis of microorganisms in samples
CN110226948A (zh) * 2009-05-27 2019-09-13 英国质谱有限公司 用于鉴定生物组织的系统和方法
US9202680B2 (en) 2009-06-03 2015-12-01 Wayne State University Mass spectometry using laserspray ionization
US8598521B2 (en) * 2009-08-17 2013-12-03 Temple University Of The Commonwealth System Of Higher Education Vaporization device and method for imaging mass spectrometry
US8546752B2 (en) 2009-12-07 2013-10-01 Advion Inc. Solid-phase extraction (SPE) tips and methods of use
AU2011214344A1 (en) 2010-02-11 2012-08-16 KATHOLIEKE UNIVERSITEIT LEUVEN, KULeuven R&D Phospholipid profiling and cancer
WO2011127091A1 (en) 2010-04-05 2011-10-13 Indiana University Research And Technology Corporation Method for enhancement of mass resolution over a limited mass range for time-of-flight spectrometry
JP5596402B2 (ja) 2010-04-19 2014-09-24 株式会社日立ハイテクノロジーズ 分析装置、イオン化装置及び分析方法
EP2567395B1 (en) 2010-05-07 2019-12-18 UT-Battelle, LLC System and method for extracting a sample from a surface
CN201811941U (zh) 2010-05-26 2011-04-27 中国石油化工股份有限公司 液体样品解析电喷雾质谱desi-ms电离装置
EP3206034B1 (en) 2010-06-23 2020-05-27 University of Louisville Research Foundation, Inc. Use of fatty acids in methods for detecting cancer
CA2805249A1 (en) 2010-07-14 2012-01-19 The Regents Of The University Of Colorado, A Body Corporate Methods and systems for in vivo clinical data measurement of analytes
US9153425B2 (en) 2010-09-01 2015-10-06 Ut-Battelle, Llc Device for high spatial resolution chemical analysis of a sample and method of high spatial resolution chemical analysis
US9552973B2 (en) 2010-09-02 2017-01-24 University Of The Sciences In Philadelphia System and method for ionization of molecules for mass spectrometry and ion mobility spectrometry
US8486703B2 (en) 2010-09-30 2013-07-16 Ut-Battelle, Llc Surface sampling concentration and reaction probe
AU2011320358B2 (en) 2010-10-29 2015-09-03 Thermo Fisher Scientific Oy Automated system for sample preparation and analysis
CN102221614B (zh) 2011-03-28 2013-07-17 山东大学 一种利用金纳米探针来鉴别小分子化合物作用靶点的分析方法
US9546979B2 (en) 2011-05-18 2017-01-17 Purdue Research Foundation Analyzing a metabolite level in a tissue sample using DESI
US9157921B2 (en) 2011-05-18 2015-10-13 Purdue Research Foundation Method for diagnosing abnormality in tissue samples by combination of mass spectral and optical imaging
US9024254B2 (en) 2011-06-03 2015-05-05 Purdue Research Foundation Enclosed desorption electrospray ionization probes and method of use thereof
JP6346567B2 (ja) * 2011-12-28 2018-06-20 マイクロマス・ユーケー・リミテッド 液相試料の急速蒸発イオン化を行うためのシステムおよび方法
US20150008314A1 (en) 2012-01-26 2015-01-08 The Cleveland Clinic Foundation Diagnostic and prognostic biomarkers for cancer
WO2013112680A1 (en) 2012-01-26 2013-08-01 University Of The Sciences In Philadelphia Ionization at intermediate pressure for atmospheric pressure ionization mass spectrometers
US9105458B2 (en) 2012-05-21 2015-08-11 Sarah Trimpin System and methods for ionizing compounds using matrix-assistance for mass spectrometry and ion mobility spectrometry
CN104603289A (zh) 2012-06-15 2015-05-06 哈里·斯泰利 检测疾病或病状的方法
WO2014045087A1 (en) 2012-09-20 2014-03-27 Oslo Universitetssykehus Hf Prostate cancer markers and uses thereof
MX367366B (es) 2012-11-27 2019-08-16 Univ Pontificia Catolica Chile Composiciones y metodos para diagnosticar tumores de tiroides.
WO2014106165A1 (en) 2012-12-30 2014-07-03 Brigham And Women's Hospital, Inc. System and method for analysis of bio-metabolites for-use in image-guided surgery
US10983126B2 (en) 2013-05-31 2021-04-20 The Brigham And Women's Hospital System and method for analyzing tissue for the presence of cancer using bio-marker profiles
WO2014209905A2 (en) 2013-06-26 2014-12-31 Stealth Peptides International, Inc. Methods and compositions for detecting and diagnosing diseases and conditions
FR3007634B1 (fr) * 2013-06-28 2016-09-02 Commissariat Energie Atomique Dispositif de prelevement in vivo d'especes biologiques et procede automatise d'analyse d'especes biologiques capturees au moyen d'un tel dispositif
WO2015009478A1 (en) * 2013-07-19 2015-01-22 Smiths Detection - Watford Limited Mass spectrometer inlet with reduced average flow
JP6323922B2 (ja) * 2013-08-07 2018-05-16 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 質量分析計供給源中への液体流れからの気泡除去
US9245722B2 (en) 2013-09-16 2016-01-26 Georgia Tech Research Corporation SMS probe and SEM imaging system and methods of use
US20160341712A1 (en) * 2013-10-23 2016-11-24 Brigham And Women's Hospital, Inc. System and method for analyzing tissue intra-operatively using mass spectrometry
WO2015100221A2 (en) 2013-12-28 2015-07-02 Purdue Research Foundation Mass spectrometry probes and systems for ionizing a sample
US20150202005A1 (en) * 2014-01-20 2015-07-23 Omniguide, Inc. System and Method To Control Surgical Energy Devices
JP2015171467A (ja) 2014-03-12 2015-10-01 セイコーエプソン株式会社 液体噴射装置および手術機器
US9297828B2 (en) 2014-03-27 2016-03-29 Ut-Battelle, Llc High heating rate thermal desorption for molecular surface sampling
US9595428B2 (en) 2014-06-17 2017-03-14 The Board Of Regents Of The University Oklahoma Cellular probe device, system and analysis method
US10000789B2 (en) 2014-06-17 2018-06-19 The Board Of Regents Of The University Of Oklahoma Cellular probe device, system and analysis method
US20160041138A1 (en) * 2014-08-11 2016-02-11 Arizona Board Of Regents On Behalf Of Arizona State University Methods for Monitoring Airborne Contaminants and Agents using Atmospheric Condensate
US10777397B2 (en) * 2015-03-06 2020-09-15 Micromass Uk Limited Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry (“REIMS”) device
GB2556436B (en) 2015-03-06 2022-01-26 Micromass Ltd Cell population analysis
US11342170B2 (en) 2015-03-06 2022-05-24 Micromass Uk Limited Collision surface for improved ionisation
CA2978048A1 (en) * 2015-03-06 2016-09-15 Micromass Uk Limited Liquid trap or separator for electrosurgical applications
GB2552602B (en) 2015-03-06 2020-12-30 Micromass Ltd Desorption electrospray ionisation mass spectrometry ("DESI-MS") analysis of swabs
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
US9632066B2 (en) 2015-04-09 2017-04-25 Ut-Battelle, Llc Open port sampling interface
US10060838B2 (en) 2015-04-09 2018-08-28 Ut-Battelle, Llc Capture probe
CN107923826B (zh) 2015-05-29 2022-03-08 普度研究基金会 用于分析组织样品的方法
GB201509402D0 (en) 2015-06-01 2015-07-15 Micromass Ltd Lock mass library for internal correction
US11266383B2 (en) 2015-09-22 2022-03-08 University Health Network System and method for optimized mass spectrometry analysis
US20170097355A1 (en) 2015-10-06 2017-04-06 University Of Washington Biomarkers and methods to distinguish ovarian cancer from benign tumors
GB2548596A (en) 2016-03-22 2017-09-27 Micromass Ltd An interface probe
WO2018013678A2 (en) 2016-07-13 2018-01-18 Board Of Regents, The University Of Texas System Molecular markers and methods for sample analysis via mass spectrometry
WO2018045208A1 (en) 2016-09-02 2018-03-08 Board Of Regents, The University Of Texas System Collection probe and methods for the use thereof
EP4357784A3 (en) * 2016-09-02 2024-07-31 Board of Regents, The University of Texas System Collection probe and methods for the use thereof
US10492801B2 (en) * 2016-09-20 2019-12-03 Osteomed Llc Power driven surgical tool
JP2021504703A (ja) 2017-11-27 2021-02-15 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 低侵襲性収集プローブおよびその使用方法
WO2019165351A1 (en) 2018-02-23 2019-08-29 Board Of Regents, The University Of Texas System Tissue analysis by mass spectrometry

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CA3083260A1 (en) 2019-05-31
US20200305723A1 (en) 2020-10-01
US20220296102A1 (en) 2022-09-22
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EP3717901A1 (en) 2020-10-07
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