MX2022008062A - Uso del agonista fxr para el tratamiento de una infeccion por el virus de la hepatitis d. - Google Patents

Uso del agonista fxr para el tratamiento de una infeccion por el virus de la hepatitis d.

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Publication number
MX2022008062A
MX2022008062A MX2022008062A MX2022008062A MX2022008062A MX 2022008062 A MX2022008062 A MX 2022008062A MX 2022008062 A MX2022008062 A MX 2022008062A MX 2022008062 A MX2022008062 A MX 2022008062A MX 2022008062 A MX2022008062 A MX 2022008062A
Authority
MX
Mexico
Prior art keywords
hepatitis
treatment
virus infection
fxr agonist
fxr
Prior art date
Application number
MX2022008062A
Other languages
English (en)
Inventor
Patrice Andre
Vincent Lotteau
Raphaël Darteil
Julie Lucifora
David Durantel
Christophe Ramiere
Benoît Lacombe
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of MX2022008062A publication Critical patent/MX2022008062A/es

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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
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    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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Abstract

La presente invención se refiere al uso de un agonista de FXR para el tratamiento de la infección por hepatitis D.
MX2022008062A 2020-01-15 2021-01-14 Uso del agonista fxr para el tratamiento de una infeccion por el virus de la hepatitis d. MX2022008062A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20305024 2020-01-15
PCT/EP2021/050625 WO2021144330A1 (en) 2020-01-15 2021-01-14 Use of fxr agonists for treating an infection by hepatitis d virus

Publications (1)

Publication Number Publication Date
MX2022008062A true MX2022008062A (es) 2022-07-27

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MX2022008062A MX2022008062A (es) 2020-01-15 2021-01-14 Uso del agonista fxr para el tratamiento de una infeccion por el virus de la hepatitis d.

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US (1) US20230060715A1 (es)
EP (1) EP4090327B1 (es)
JP (1) JP2023510274A (es)
KR (1) KR20220128402A (es)
CN (1) CN114945361A (es)
AU (1) AU2021207253A1 (es)
CA (1) CA3159163A1 (es)
ES (1) ES3014367T3 (es)
IL (1) IL293892A (es)
MX (1) MX2022008062A (es)
WO (1) WO2021144330A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117320722A (zh) * 2021-04-28 2023-12-29 埃尼奥制药公司 使用fxr激动剂作为联合治疗强烈增强tlr3激动剂的作用
WO2024184345A1 (en) 2023-03-06 2024-09-12 Enyo Pharma Synergistic effect of an fxr agonist and ifn for the treatment of chronic hdv infection

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ES2326850T3 (es) 1998-12-23 2009-10-20 Glaxo Group Limited Ensayos para ligandos de receptores nucleares.
AU2409600A (en) 1999-01-07 2000-07-24 Tularik Inc. Fxr receptor-mediated modulation of cholesterol metabolism
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CN1368884A (zh) 1999-06-11 2002-09-11 阿勒根销售公司 用于调节fxr受体活性的方法
ATE303399T1 (de) 2001-03-12 2005-09-15 Intercept Pharmaceuticals Inc Steroide als agonisten für fxr
EP1423113A4 (en) 2001-08-13 2007-04-18 Phenex Pharmaceuticals Ag NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS
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