MX3022E - Mejoras en procedimiento para la obtencion de uroquinasa - Google Patents
Mejoras en procedimiento para la obtencion de uroquinasaInfo
- Publication number
- MX3022E MX3022E MX006395U MX639575U MX3022E MX 3022 E MX3022 E MX 3022E MX 006395 U MX006395 U MX 006395U MX 639575 U MX639575 U MX 639575U MX 3022 E MX3022 E MX 3022E
- Authority
- MX
- Mexico
- Prior art keywords
- procedure
- parts
- nutrient medium
- aqueous nutrient
- urokinase
- Prior art date
Links
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 title abstract 2
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229960005356 urokinase Drugs 0.000 title abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 235000015097 nutrients Nutrition 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 210000003292 kidney cell Anatomy 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 230000000050 nutritive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La presente invención se refiere a mejoras en procedimiento para la obtención de uroquinasa a partir de un cultivo contiguo de células de riñón vivas en un medio nutritivo acuoso, caracterizadas porque el medio nutritivo acuoso contiene, además de los aditivos de mantenimiento del cultivo de células usuales, entre 0.3 y 1.2 partes por peso de glicina por 100 partes por volumen del nutritivo mencionado; de preferencia, el cultivo se realiza a 37+-0.5°C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/564,966 US3930945A (en) | 1975-03-31 | 1975-03-31 | Urokinase production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX3022E true MX3022E (es) | 1980-02-13 |
Family
ID=24256647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX006395U MX3022E (es) | 1975-03-31 | 1975-10-02 | Mejoras en procedimiento para la obtencion de uroquinasa |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3930945A (es) |
| JP (1) | JPS51128490A (es) |
| AR (1) | AR208001A1 (es) |
| BE (1) | BE835023A (es) |
| CA (1) | CA1054085A (es) |
| CH (1) | CH601477A5 (es) |
| DE (1) | DE2551017C3 (es) |
| DK (1) | DK140561B (es) |
| FR (1) | FR2306263A1 (es) |
| GB (1) | GB1491816A (es) |
| MX (1) | MX3022E (es) |
| NL (1) | NL164898C (es) |
| PH (1) | PH11173A (es) |
| SE (1) | SE415035B (es) |
| ZA (1) | ZA756194B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190708A (en) * | 1978-05-24 | 1980-02-26 | Monsanto Company | Production of urokinase |
| JPS5571496A (en) * | 1978-11-24 | 1980-05-29 | Asahi Chem Ind Co Ltd | Preparation of living substance |
| US4232124A (en) * | 1979-04-23 | 1980-11-04 | Mann George F | Method of producing plasminogen activator |
| DE3015699C2 (de) * | 1979-04-26 | 1982-07-15 | Asahi Kasei Kogyo K.K., Osaka | Herstellung eines Plasminogen-Aktivators |
| JPS5852634B2 (ja) * | 1980-12-05 | 1983-11-24 | 株式会社林原生物化学研究所 | ウロキナ−ゼの製造法 |
| DE3584902D1 (de) * | 1984-02-29 | 1992-01-30 | Asahi Chemical Ind | Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren. |
| US4661453A (en) * | 1984-06-19 | 1987-04-28 | American Biogenetic Sciences, Inc. | Production of tissue plasminogen activator factor |
| JPS61207335A (ja) * | 1985-03-12 | 1986-09-13 | Kouchi Ika Univ | 悪性リンパ腫細胞株ｒｃ−ｋ８の産生するプラスミノゲン・アクチベ−タ− |
| US4920051A (en) * | 1988-02-03 | 1990-04-24 | Damon Biotech, Inc. | Recovery of urokinase compounds |
-
1975
- 1975-01-01 AR AR261024A patent/AR208001A1/es active
- 1975-03-31 US US05/564,966 patent/US3930945A/en not_active Expired - Lifetime
- 1975-09-30 ZA ZA00756194A patent/ZA756194B/xx unknown
- 1975-10-01 CA CA236,800A patent/CA1054085A/en not_active Expired
- 1975-10-02 MX MX006395U patent/MX3022E/es unknown
- 1975-10-06 GB GB40878/75A patent/GB1491816A/en not_active Expired
- 1975-10-09 NL NL7511872.A patent/NL164898C/xx not_active IP Right Cessation
- 1975-10-30 BE BE2054638A patent/BE835023A/xx not_active IP Right Cessation
- 1975-10-31 JP JP50130577A patent/JPS51128490A/ja active Granted
- 1975-11-10 FR FR7534342A patent/FR2306263A1/fr active Granted
- 1975-11-10 CH CH1451175A patent/CH601477A5/xx not_active IP Right Cessation
- 1975-11-11 PH PH17759A patent/PH11173A/en unknown
- 1975-11-13 SE SE7512782A patent/SE415035B/xx unknown
- 1975-11-13 DE DE2551017A patent/DE2551017C3/de not_active Expired
- 1975-11-14 DK DK515375AA patent/DK140561B/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU8545175A (en) | 1977-04-07 |
| JPS5414190B2 (es) | 1979-06-05 |
| GB1491816A (en) | 1977-11-16 |
| CH601477A5 (es) | 1978-07-14 |
| DK515375A (es) | 1976-10-01 |
| NL7511872A (nl) | 1976-10-04 |
| NL164898B (nl) | 1980-09-15 |
| US3930945A (en) | 1976-01-06 |
| BE835023A (fr) | 1976-04-30 |
| FR2306263B1 (es) | 1979-06-01 |
| JPS51128490A (en) | 1976-11-09 |
| SE415035B (sv) | 1980-09-01 |
| PH11173A (en) | 1977-10-28 |
| DE2551017B2 (de) | 1978-01-19 |
| SE7512782L (sv) | 1976-10-01 |
| DK140561B (da) | 1979-10-01 |
| DK140561C (es) | 1980-03-17 |
| FR2306263A1 (fr) | 1976-10-29 |
| CA1054085A (en) | 1979-05-08 |
| DE2551017A1 (de) | 1976-10-07 |
| NL164898C (nl) | 1981-02-16 |
| DE2551017C3 (de) | 1978-09-21 |
| ZA756194B (en) | 1976-09-29 |
| AR208001A1 (es) | 1976-11-22 |
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